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Search Results: 1 - 10 of 1203 matches for " Owen Pyeko Menach "
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Demography and Histologic Pattern of Laryngeal Squamous Cell Carcinoma in Kenya
Owen Pyeko Menach,Asmeeta Patel,Herbert Ouma Oburra
International Journal of Otolaryngology , 2014, DOI: 10.1155/2014/507189
Abstract: Background. Laryngeal squamous cell carcinoma is a common head and neck cancer worldwide. Objective. To determine the demographic characteristics of patients with laryngeal cancer, establish their tumor characteristics and relate it to their smoking and alcohol ingestion habits. Methods. Fifty cases and fifty controls were recruited of matching age, sex, and region of residence. History and pattern of cigarette smoking and alcohol ingestion was taken and analyzed. Results. 33 (66%) of the cases and 3 (6%) among controls were current cigarette smokers. 74% had smoked for more than 30 years, OR 21.3 (95% CI: 2.6–176.1). There was a male predominance (96%) and most cases (62%) were from the ethnic communities in the highland areas of Kenya predominantly in Central and Eastern provinces. Very heavy drinkers had increased risk of OR, 6.0 (95% CI: 1.957–18.398) and those who smoked cigarettes and drank alcohol had poorly differentiated tumors G3, , OR 11.652 (95% CI 2.305–58.895), and G4, OR 7.286 (95% CI 0.726–73.075). They also presented with advanced disease (73.6%). Conclusion. Cigarette smoking and alcohol ingestion are strong risk factors for development of late stage and poorly differentiated laryngeal squamous cell carcinoma in Kenya. 1. Background The commonest causes of death in Kenya are infectious diseases followed closely by cardiovascular illnesses and cancer in that order [1]. Cancer cases in Kenya have however been steadily rising due to the increasing prevalence of cigarette smoking which is a known cause of various neoplasias, more so the upper aerodigestive tract and lung tumors [1, 2]. This rise has been documented and published by the Nairobi Cancer Registry [3], but it is not thought to depict the accurate situation on the ground because cancer diagnosis and notification from health institutions are not as meticulous as desirable. This increase has not been captured in local studies especially with regard to head and neck cancer in general and laryngeal carcinoma in particular. From previous published work, cigarette smoking and alcohol ingestion have been shown to be major risk factors for laryngeal squamous cell carcinoma in this locality as seen in other populations [4]. The incidence of this cancer may increase considering the rising prevalence of smoking in Kenya especially among men in the 45–49 years of age bracket [1, 2]. Moreover, it is also quite worrying that 13% of schooling children smoke cigarettes and, just like in adults, males smoke more than females [5, 6]. If not checked, there is likelihood of increased cancer burden
Cigarette Smoking and Alcohol Ingestion as Risk Factors for Laryngeal Squamous Cell Carcinoma at Kenyatta National Hospital, Kenya
Pyeko Menach, Herbert O. Oburra and Asmeeta Patel
Clinical Medicine Insights: Ear, Nose and Throat , 2012, DOI: 10.4137/CMENT.S8610
Abstract: Laryngeal squamous cell carcinoma (SCC) is strongly linked to cigarette smoking. It is estimated to account for more than 70% of laryngeal SCCs and up to 89% in combination with alcohol. We wished to determine the prevalence of cigarette smoking and alcohol ingestion among patients with laryngeal squamous cell carcinoma and estimate risk attributed to cigarette smoking and alcohol ingestion. Fifty experimental group patients and fifty controls were recruited of matching age, sex and region of residence. History of smoking and alcohol intake was taken and analyzed to estimate the relative strengths of these exposures. Cessation of smoking was associated with reduced risk of SCC. Smokers had increased risk compared to controls. Those who smoked only had a higher glottic cancer risk. Those who smoked and drank alcohol had a higher supraglottic cancer risk. Being a current smoker and long duration of smoking were independent risk factors of laryngeal SCC.
Cigarette Smoking and Alcohol Ingestion as Risk Factors for Laryngeal Squamous Cell Carcinoma at Kenyatta National Hospital, Kenya
Pyeko Menach,Herbert O. Oburra,Asmeeta Patel
Clinical Medicine Insights: Ear, Nose and Throat , 2012,
The unexpected importance of mosquito oviposition behaviour for malaria: non-productive larval habitats can be sources for malaria transmission
Arnaud Menach, F Ellis McKenzie, Antoine Flahault, David L Smith
Malaria Journal , 2005, DOI: 10.1186/1475-2875-4-23
Abstract: Biting and host seeking, not oviposition, have been the focus of most previous studies of mosquitoes and malaria transmission. This study presents a mathematical model that incorporates mosquito oviposition behaviour.The model demonstrates that oviposition is one potential factor explaining heterogeneous biting and vector distribution in a landscape with a heterogeneous distribution of larval habitat. Adult female mosquitoes tend to aggregate around places where they oviposit, thereby increasing the risk of malaria, regardless of the suitability of the habitat for larval development. Thus, a water body may be unsuitable for adult mosquito emergence, but simultaneously, be a source for human malaria.Larval density may be a misleading indicator of a habitat's importance for malaria control. Even if mosquitoes could be lured to oviposit in sprayed larval habitats, this would not necessarily mitigate – and might aggravate – the risk of malaria transmission. Forcing mosquitoes to fly away from humans in search of larval habitat may be a more efficient way to reduce the risk of malaria than killing larvae. Thus, draining, fouling, or filling standing water where mosquitoes oviposit can be more effective than applying larvicide.Malaria is responsible for 700,000 to 2.3 million deaths each year, mainly among children [1]. It is caused by four species of Plasmodium, protozoan parasites that are most common in the tropics, especially Africa, and are transmitted between humans by the bites of female Anopheles mosquitoes. Thus, the distribution of Anopheles mosquitoes is an important factor in determining the prevalence of Plasmodium infections in humans. At large spatial scales (i.e. 100–1,000 kilometers), the distribution of malaria is best described by climate: warm, humid places with standing water support large mosquito populations and high malaria prevalence. At local scales (i.e. 100 metres to one kilometre), the risk of malaria is determined by mosquito behaviour and ec
Corporate Character Formation and CSR: The Function of Habit and Practice in the Mining Industry  [PDF]
John R. Owen, Deanna Kemp
American Journal of Industrial and Business Management (AJIBM) , 2014, DOI: 10.4236/ajibm.2014.45030

The mining industry provides a rich context through which to engage the practical and ethical limits of Corporate Social Responsibility (CSR). Recent debates in organizational ethics have drawn attention to institutional constraints which inhibit awareness raising and ethical practice within corporate settings. During the last decade, the mining industry has come under increasing pressure to improve its environmental, social and ethical performance. In an effort to respond to these more ethically-orientated external expectations, the mining industry has developed a range of internal regulatory mechanisms and process, which can be applied individually or in conjunction with other companies and organizations. This combination of internal and external drivers indicates a growing imperative for mining companies to ground CSR principles in their day-to-day operating practices. The challenge is to avoid organizational rules and procedures for CSR that lack depth and meaning and which fail to result in the wise and courageous use of personal agency. Instead mining companies must work to establish appropriate mechanisms that will see ethical norms adopted as organizational principles that guide, and result in, improved corporate conduct. Using the Aristotelean notion of “character formation”, the authors offer practical considerations for how this might occur in the mining industry.

Selection for prolificacy in the Cambridge sheep
JB Owen
Genetics Selection Evolution , 1982, DOI: 10.1186/1297-9686-14-4-579c
The development of a prolific breed of sheep
JB Owen
Genetics Selection Evolution , 1977, DOI: 10.1186/1297-9686-9-1-128b
Apendicitis aguda sin dolor o "El paraíso de los tontos": Caso clínico
Revista médica de Chile , 2008, DOI: 10.4067/S0034-98872008001200008
Abstract: the diagnosis of acute appendicitis has been based on the presence of ríght lower quadrant pain and guarding. occasionally, the pain disappears, even in the presence of a continuing appendicular process. this phenomenon is called "the fools' paradise". we report two male patients aged 19 and 17 years with an acute appendicitis confirmed by an abdominal ultrasound in one and an abdominal cat sean in the other, in whom the abdominal pain disappeared during the evolution. despite of the absence of pain, both were operated, based on imaging and laboratory studies, confirming the presence of an inflamed appendix.
The Internet and Healthcare in Somalia: Knowledge is Power
Owen Marriott
Global Media Journal : African Edition , 2011, DOI: 10.5789/2-1-39
Abstract: The introduction of the eight Millennium Development Goals (MDG’s) by the UN has highlighted the need to improve healthcare conditions across the globe. These goals are particularly pertinent in Somalia, one of the least developed countries in the world. This paper intends to look at the way the burgeoning telecommunications network in Somalia can benefit healthcare professionals by providing access to the internet which in turn provides access to information that can improve healthcare. The paper will argue that although the development of healthcare is commonly associated with the modernization paradigm, the internet can offer a more participatory approach to benefit healthcare professionals in Somalia.
A Case in Favour of Radicalisation: a Commentary on Issues Surrounding the Caldicott Report
Matthew Owen
Opticon1826 , 2010, DOI: 10.5334/opt.091008
Abstract: The premise of this commentary is that the terms ‘radical’ and ‘radicalisation’ need to be defended. These terms are being unfairly bracketed with ‘violent extremism’. Extremist atrocities, whether implemented by terrorist groups (e.g. destruction of the Twin Towers) or governments (e.g. Hitler’s final solution), are just those: atrocities to be condemned. Radicalism, however, is a desire to bring about substantive change, and in its simplest form this term is divorced from any moral or ethical connotation. I will contextualize this debate using the example of Umar Farouk Abdulmutallab, the former University College London (UCL) student charged with attempting to blow up a US airliner. A discussion of what is meant by radicalisation will follow, after which some examples of well-known radicals will be presented. Finally, I shall argue that contemporary society is ‘bust’ and that we need radical ideas and radical people in order to ‘fix’ our future society. As such, we need radicalisation within society in general and universities in particular.
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