oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2016 ( 2 )

2015 ( 18 )

2014 ( 19 )

2013 ( 24 )

Custom range...

Search Results: 1 - 10 of 225 matches for " Orestis Ioannidis "
All listed articles are free for downloading (OA Articles)
Page 1 /225
Display every page Item
Concordance of Sleep and Pain Outcomes of Diverse Interventions: An Umbrella Review
Anthony G. Doufas, Orestis A. Panagiotou, John P. A. Ioannidis
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040891
Abstract: Background/Objective Pain influences sleep and vice versa. We performed an umbrella review of meta-analyses on treatments for diverse conditions in order to examine whether diverse medical treatments for different conditions have similar or divergent effects on pain and sleep. Methods We searched published systematic reviews with meta-analyses in the Cochrane Database of Systematic Reviews until October 20, 2011. We identified randomized trials (or meta-analyses thereof, when >1 trial was available) where both pain and sleep outcomes were examined. Pain outcomes were categorized as headache, musculoskeletal, abdominal, pelvic, generic or other pain. Sleep outcomes included insomnia, sleep disruption, and sleep disturbance. We estimated odds ratios for all outcomes and evaluated the concordance in the direction of effects between sleep and various types of pain and the correlation of treatment effects between sleep and pain outcomes. Results 151 comparisons with 385 different trials met our eligibility criteria. 96 comparisons had concordant direction of effects between each pain outcome and sleep, while in 55 the effect estimates were in opposite directions (P<0.0001). In the 20 comparisons with largest amount of evidence, the experimental drug always had worse sleep outcomes and tended to have worse pain outcomes in 17/20 cases. For headache and musculoskeletal pain, 69 comparisons showed concordant direction of effects with sleep outcomes and 36 showed discordant direction (P<0.0001). For the other 4 pain types there were overall 27 vs. 19 pairs with concordant vs. discordant direction of effects (P = 0.095). There was a weak correlation of the treatment effect sizes for sleep vs. headache/musculoskeletal pain (r = 0.17, P = 0.092). Conclusions Medical interventions tend to have effects in the same direction for pain and sleep outcomes, but exceptions occur. Concordance is primarily seen for sleep and headache or musculoskeletal pain where many drugs may both disturb sleep and cause pain.
Recurrent small intestine intussusception in a patient with Peutz-Jeghers syndrome Invaginación recurrente del intestino delgado en un paciente con síndrome de Pentz-Jeghers
Orestis Ioannidis,Styliani Papaemmanouil,George Paraskevas,Anastasios Kotronis
Revista Espa?ola de Enfermedades Digestivas , 2012,
Abstract: Peutz-Jeghers syndrome is a rare hereditary autosomal dominant disease caused by a mutation of the tumor suppressor gene serine/threonine kinase 11 located in chromosome 19p13.3. It is characterized by the presence of extensive mucocutaneous pigmentation, especially of the lips and the occurrence of hamartomatous polyps throughout the gastrointestinal tract. Gastrointestinal hamartomas occur predominantly in the small intestine and can become symptomatic leading usually to intestinal obstruction and abdominal pain. We present a case of recurrent intestinal obstruction caused by small bowel intussusception treated by reduction, enterotomy and polypectomy and followed by intraoperative enteroscopy and endoscopic polypectomy.
Omega 3 fatty acids supplementation has an ameliorative effect in experimental ulcerative colitis despite increased colonic neutrophil infiltration Los suplementos de ácidos grasos omega 3 tienen efectos beneficiosos en colitis ulcerosa a pesar del aumento de la infiltracción por neutrófilos del colon
Ioannis Varnalidis,Orestis Ioannidis,Elisavet Karamanavi,Zafeiris Ampas
Revista Espa?ola de Enfermedades Digestivas , 2011,
Abstract: Purpose: omega 3 polyunsaturated fatty acids have anti-inflammatory properties and can be beneficial in the treatment of inflammatory diseases, such as ulcerative colitis. Dextran sodium sulphate (DSS) colitis in rats appears to mimic nearly all of the morphological characteristics and lesion distributions of ulcerative colitis. The purpose of the current study was to investigate the efficacy of omega 3 fatty acids in the treatment of experimental ulcerative colitis. Methods: thirty-six Wistar rats were randomly assigned to group A or group B receiving 5% dextran sulfate sodium (DSS) in their drinking water for eight days. For the next eight days post-DSS, group A animals received tap-water, and group B animals were fed a nutritional solution containing high levels of omega 3 polyunsaturated fatty acids (ProSure , Abbott Laboratories, Zwolle, Netherlands) once per day, administrated with a orogastric feeding tube. Results: animals fed an omega 3 rich diet exhibited a statistically significant increase in hematocrit and hemoglobin levels, compared to animals drinking tap water, and a trend towards histopathological and clinical improvement, with the administration of omega 3 fatty acids ameliorating epithelial erosion by day 8 post-DSS, but no statistically significant difference was observed between group A and group B animals at 4 or 8 days post-DSS. Also, a statistically significant increase in neutrophil infiltration was observed, as depicted by myelohyperoxidase activity. Conclusion: our findings support a positive role of omega 3 polyunsaturated fatty acids supplementation in an experimental model of ulcerative colitis despite the increased colonic neutrophil infiltration. Further studies are needed in order to investigate the role of increased neutrophils in colonic mucosa.
Multiple desmoid tumors in a patient with familial adenomatous polyposis caused by the novel W421X mutation Tumor desmoide múltiple en un paciente con poliposis adenomatosa familiar originada por la nueva mutación W421X
Orestis Ioannidis,George Paraskevas,Stavros Chatzopoulos,Anastasios Kotronis
Revista Espa?ola de Enfermedades Digestivas , 2012,
Abstract: Familial adenomatous polyposis (FAP) is a rare syndrome characterized by the presence of hundreds to thousands of colorectal adenomas and is responsible for less than 1% of all colorectal cancers. The syndrome is also characterized by extra-colorectal features including amongst others upper gastrointestinal tract polyps and desmoid tumors. The syndrome is inherited by an autosomal dominant gene, the adenomatous polyposis coli (APC) gene. We present the physical history, clinical presentation, diagnosis and treatment of a patient with a novel germline APC mutation, the W421X mutation, which resulted in FAP presenting with about a hundred colorectal polyps, gastric hyperplastic polyps and multiple aggressive intra-abdominal and extra-abdominal desmoid tumors.
Pseudomyxoma retroperitonei: report of 2 cases and review of the literature Pseudomixoma retroperitonal: informe de 2 casos y revisión de la literatura
Orestis Ioannidis,Angeliki Cheva,George Paraskevas,Nikolaos Papadimitriou
Revista Espa?ola de Enfermedades Digestivas , 2012,
Abstract: Pseudomyxoma peritonei is a rare clinical condition that is characterized by the presence of mucinous ascitis. It is believed to originate predominately from a mucinous neoplasm of the appendix including a heterogeneous group of tumours ranging from indolent to malignant. It was first described in the late 19th century. Pseudomyxoma retroperitonei is extremely rare with only 33 cases having been reported since the first description in the middle of the 20th century. We report two additional cases of pseudomyxoma retroperitonei and present a review of the literature.
High origin of a testicular artery: a case report and review of the literature
George K Paraskevas, Orestis Ioannidis, Athanasios Raikos, Basileios Papaziogas, Konstantinos Natsis, Ioannis Spyridakis, Panagiotis Kitsoulis
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-75
Abstract: We report a very rare case of high origin of the left testicular artery in a 68-year-old Caucasian male cadaver. The artery originated from the anterolateral aspect of the abdominal aorta, 2 cm cranially to the ipsilateral renal artery. Approximately 1 cm after its origin, it branched off into the inferior suprarenal artery. During its course, the artery crossed anterior to the left renal artery.A knowledge of the variant origin of the testicular artery is important during renal and testicular surgery. The origin and course must be carefully identified in order to preserve normal blood circulation and prevent testicular atrophy. A reduction in gonadal blood flow may lead to varicocele under circumstances. A knowledge of this variant anatomy may be of interest to radiologists and helpful in avoiding diagnostic errors.The testis mainly receives its blood supply from the testicular artery (TA) and drains into the testicular vein [1]. Testicular vessels have an important role in testis thermoregulation [2]. Variations of these arteries and veins have been extensively studied due to their importance in testicular physiology. Moreover, this knowledge has a practical implication during renal and testicular surgery.Anomalies in the origin, course, and number of TAs were observed in 4.7 percent of cases in a study of 150 cadavers [2]. A high origin of the TA from the abdominal aorta, as in our case report, has been noted in only a few instances in the literature [3-6]. We report on such a case and review the relative literature about the macroscopic anatomy, embryology and likely physiological and surgical implications of this variant.We identified a variation in the origin of the TA in a 68-year-old Caucasian male formalin-embalmed cadaver used for educational and research purposes. His cause of death was cardiovascular ischemic disease. Following dissection of the retro-peritoneum and preparation of the abdominal aorta and its branches, an unusual high origin of the left T
Abnormal origin of internal thoracic artery from the thyrocervical trunk: surgical considerations
George K Paraskevas, Konstantinos Natsis, Maria Tzika, Orestis Ioannidis, Panagiotis Kitsoulis
Journal of Cardiothoracic Surgery , 2012, DOI: 10.1186/1749-8090-7-63
Abstract:
Omega 3 fatty acids supplementation has an ameliorative effect in experimental ulcerative colitis despite increased colonic neutrophil infiltration
Varnalidis,Ioannis; Ioannidis,Orestis; Karamanavi,Elisavet; Ampas,Zafeiris; Poutahidis,Theofilos; Taitzoglou,Ioannis; Paraskevas,George; Botsios,Dimitrios;
Revista Espa?ola de Enfermedades Digestivas , 2011, DOI: 10.4321/S1130-01082011001000003
Abstract: purpose: omega 3 polyunsaturated fatty acids have anti-inflammatory properties and can be beneficial in the treatment of inflammatory diseases, such as ulcerative colitis. dextran sodium sulphate (dss) colitis in rats appears to mimic nearly all of the morphological characteristics and lesion distributions of ulcerative colitis. the purpose of the current study was to investigate the efficacy of omega 3 fatty acids in the treatment of experimental ulcerative colitis. methods: thirty-six wistar rats were randomly assigned to group a or group b receiving 5% dextran sulfate sodium (dss) in their drinking water for eight days. for the next eight days post-dss, group a animals received tap-water, and group b animals were fed a nutritional solution containing high levels of omega 3 polyunsaturated fatty acids (prosure?, abbott laboratories, zwolle, netherlands) once per day, administrated with a orogastric feeding tube. results: animals fed an omega 3 rich diet exhibited a statistically significant increase in hematocrit and hemoglobin levels, compared to animals drinking tap water, and a trend towards histopathological and clinical improvement, with the administration of omega 3 fatty acids ameliorating epithelial erosion by day 8 post-dss, but no statistically significant difference was observed between group a and group b animals at 4 or 8 days post-dss. also, a statistically significant increase in neutrophil infiltration was observed, as depicted by myelohyperoxidase activity. conclusion: our findings support a positive role of omega 3 polyunsaturated fatty acids supplementation in an experimental model of ulcerative colitis despite the increased colonic neutrophil infiltration. further studies are needed in order to investigate the role of increased neutrophils in colonic mucosa.
Multiple desmoid tumors in a patient with familial adenomatous polyposis caused by the novel W421X mutation
Ioannidis,Orestis; Paraskevas,George; Chatzopoulos,Stavros; Kotronis,Anastasios; Papadimitriou,Nikolaos; Konstantara,Athina; Makrantonakis,Apostolos; Kakoutis,Emmanouil;
Revista Espa?ola de Enfermedades Digestivas , 2012, DOI: 10.4321/S1130-01082012000300009
Abstract: familial adenomatous polyposis (fap) is a rare syndrome characterized by the presence of hundreds to thousands of colorectal adenomas and is responsible for less than 1% of all colorectal cancers. the syndrome is also characterized by extra-colorectal features including amongst others upper gastrointestinal tract polyps and desmoid tumors. the syndrome is inherited by an autosomal dominant gene, the adenomatous polyposis coli (apc) gene. we present the physical history, clinical presentation, diagnosis and treatment of a patient with a novel germline apc mutation, the w421x mutation, which resulted in fap presenting with about a hundred colorectal polyps, gastric hyperplastic polyps and multiple aggressive intra-abdominal and extra-abdominal desmoid tumors.
Acute respiratory failure caused by neglected giant substernal nontoxic goiter
Ioannidis, Orestis;Dalampini, Eleftheria;Chatzopoulos, Stavros;Kotronis, Anastasios;Paraskevas, George;Konstantara, Athina;Papadimitriou, Nikolaos;Makrantonakis, Apostolos;Kakoutis, Emmanouil;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2011, DOI: 10.1590/S0004-27302011000300009
Abstract: substernal goiter is usually defined as a goiter in which the thyroid mass has descended the plane of the thoracic inlet or if more than 50% of the thyroid mass is located below the thoracic inlet. substernal goiters may be asymptomatic or may present with symptoms caused by compression of adjacent organs. acute respiratory failure is rare in cases of substernal goiter. in cases of symptomatic substernal goiter the treatment is surgical by thyroidectomy. we present a rare case of a giant substernal nontoxic goiter which caused acute respiratory failure which was treated by urgent thyroidectomy through a t-incision.
Page 1 /225
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.