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Search Results: 1 - 10 of 599 matches for " Onur Yalcin "
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Annular Pancreas in Children: A Decade of Experience
Murat Yigiter,Abdullah Yildiz,Binali Firinci,Onur Yalcin
Eurasian Journal of Medicine , 2010,
Abstract: Objective: Annular pancreas is an uncommon cause of duodenal obstruction in children. In this study, the clinical, radiological, and prognostic findings related to this disorder over a 12-year review period were analyzed.Materials and Methods: A retrospective review of 22 patients with annular pancreas who were treated with surgical repair between April 1998 and February 2010 was performed at two different pediatric surgical units. Presenting symptoms, associated anomalies, radiological findings, the type of surgery performed, postoperative outcomes, and complications were analyzed.Results: Twenty-two patients were identified. Thirteen of the 22 patients (59.1%) were born prematurely, 11 patients (50%) had low birth weight, 2 patients (9.1%) had very low birth weight and 1 patient (4.5%) had extremely low birth weight. The mean birth weight was 2285.23±675.12 g. (970-3300). All patients presented with vomiting, which was bilious in nine (40.9%). Nine patients (40.9%) had chromosomal anomalies. Corrective surgery consisted of duodenoduodenostomy in 9 patients (40.9 %), duodenojejunostomy in 9 patients (40.9%), and gastrojejunostomy in 4 patients (18.1%). Fourteen of the 22 patients have survived (63.6%). The causes of death were combinations of sepsis, pneumonia, brain hemorrhage, and cardiac anomaly. Conclusion: Infants with annular pancreas associated with duodenal obstruction were often born prematurely and/or had low birth weights; many had cardiovascular anomalies. Annular pancreas associated with duodenal obstruction correlated strongly with the trisomy 21 karyotype among the chromosomal anomalies, as did duodenal atresia. The oral feeding tolerance time was nearly the same for all patients regardless of the surgical procedure used.
Investigation of the Effects of Zebularine on Caspase-3 and Caspase-9 Involved in Anticancer and Apoptotic Mechanisms in SKBR3 Breast Cancer Cell Line  [PDF]
Onur Eroglu, Merve Celen
Journal of Cancer Therapy (JCT) , 2019, DOI: 10.4236/jct.2019.103019
Abstract: The aim of this study is to investigate the anti-proliferative effects of Zebularine on caspase-3 and 9 genes by methylation and protein expression on SKBR3 cells. The SKBR3 cells were treated with Zebularine at different concentrations (0 - 140 μM) for 24 - 96 hours and the effects on the cell viability were shown. The effects on the cell migration and cell transformation were also demonstrated at the specified dose (IC50 = 40 μM). At the same time, the HRM method and western-blot analysis were used to understand the effects in the apoptotic mechanism. According to the obtained results, it was observed that Zebularine significantly decreased the cell proliferation, cell migration and the cell growth (p < 0.001). As a result of the methylation analyzes performed on SKBR-3 cells at the applied dose, it was observed that Zebularine caused a decrease in both caspase-3 and 9 methylation rates at the 72nd hour. However, both reductions in the methylation levels didn’t cause a significant change (p > 0.05). At the same time, it was detected by the western-blot analyses that there was a time dependent increase in caspase-3 genes while a decrease was detected in the caspase-9 gene in progress of time. The obtained results showed that the methylation changes occurring in the caspase genes weren’t related to the protein levels. According to these results, supportive results are obtained showing that the Zebularine c
Scattering from Perfectly Magnetic Conducting Surfaces: the Extended Theory of Boundary Diffraction Wave Approach
Ugur Yalcin
PIER M , 2009, DOI: 10.2528/PIERM09042210
Abstract: In this paper, the uniform scattered fields from a perfectly magnetic conducting (PMC) surface are studied with the theory of boundary diffraction wave (TBDW). The vector potential is described by considering the TBDW for the PMC surfaces. The TBDW is then applied to the problem of scattering from the PMC half plane. The total scattered fields are obtained and compared numerically with the exact solution for the same problem. The numerical results show that the solution of the TBDW is very the exact solution.
Uniform Scattered Fields of the Extended Theory of Boundary Diffraction Wave for PEC Surfaces
Ugur Yalcin
PIER M , 2009, DOI: 10.2528/PIERM09031201
Abstract: In this paper, the uniform scattered fields from a perfectly conducting (PEC) half plane are studied with the extended theory of the boundary diffraction wave. A new vector potential of the boundary diffraction wave is found by considering the Fermat principle for the PEC surfaces. This vector potential is applied to the Helmholtz-Kirchhoff integral, and the theory of the boundary diffraction wave is extended to the PEC surfaces. The extended theory of the boundary diffraction wave is then applied to the scattering problem for the PEC half plane. The total scattered fields are compared numerically with the exact solution for the same problem. The numerical comparisons given in the paper show that the solution of the extended theory of the boundary diffraction wave is very close to the exact solution.
Socioeconomic burden of nosocomial infections.
Yalcin Ata
Indian Journal of Medical Sciences , 2003,
Abstract: Nosocomial infection represents an important public health problem in developing countries as in developed ones. Economic concerns have taken on increasing importance in infection control since the mid 1970s in the USA, however there are few papers on the economics of NI in other countries. Studies on the costs of NI have used different methods, definitions and degrees of stringency when calculating indirect costs and there is therefore still uncertainty over their true economic impact on the community and on the workplace economy. Drug and especially antibiotic acquisition in addition to increased length of stay are the widely and well described parameters. Extra cost of NI include; bed, intensive care unit stay, hematological, biochemical, microbiological and radiological tests, antibiotics, other drugs, extra surgical procedures and working hours. In addition to high morbidity and mortality one of the well described parameters is the extra length of stay in the hospital. High mortality rates and economic expense which NI represents emphasizes the justification for measures of control of this entity. To estimate better the current personnel and financial resources necessary to support infection control activities and to prevent NI, it is imperative that those conducting studies of hospital epidemiology and healthcare outcomes research determine these current costs.
Refining of Polysulfide Pulps
Yalcin Copur
Journal of Applied Sciences , 2007,
Abstract: This study compares the modified kraft process, polysulfide pulping, one of the methods to obtain higher pulp yield, with conventional kraft method. More specifically, the study focuses on the refining effects of polysulfide pulp, which is an area with limited literature. Physical, mechanical and chemical properties of kraft and polysulfide pulps (4% elemental sulfur addition to cooking digester) cooked under the same conditions were studied as regards to their behavior under various PFI refining (0, 3000, 6000, 9000 revs.). Polysulfide (PS) pulping, compared to the kraft method, resulted in higher pulp yield and higher pulp kappa number. Polysulfide also gave pulp having higher tensile and burst index. However, the strength of polysulfide pulp, tear index at a constant tensile index, was found to be 15% lower as compared to the kraft pulp. Refining studies showed that moisture holding ability of chemical pulps mostly depends on the chemical nature of the pulp. Refining effects such as fibrillation and fine content did not have a significant effect on the hygroscopic behavior of chemical pulp.
Poliovirus Vaccines
Isik Yalcin
Cocuk Enfeksiyon Dergisi , 2008,
Abstract: The two types of poliovirus vaccines are inactivated vaccine, given parenterally, and live virus vaccine, given orally. Oral poliovirus is the vaccine of choice for global eradication. Either inactivated vaccine or oral vaccine may be given concurrently with other routinely recommended childhood vaccines. No serious adverse events have been associated with the vaccine. Oral poliovirus vaccine can cause vaccine associated paralytic poliomyelitis.
General Conceptual View on Resource Advantage Theory
Bilal Yalcin
Business and Economics Research Journal , 2010,
Abstract: In order to continue for an organization to exist it needs to finance itself for its own resource on the other hand service with considering consumers need and expectations by present them lowest price and highest quality also. Under these conditions these kind of organizations need to analyze the behaviour (nature) of the rival organizations and position themselves accordingly in order to get advantage on the rival organizations. In this study, a general conceptual view on resource advantage theory is developed. Theory explains having the lowest cost resources than rival organisations geting advantage with organisation resources, market position, financial performance and evironmental factors. Theory is able to achieve efficiency and effectiveness in the organisations and use to have strategic marketing decisions.
Productive elements in group cohomology
Ergun Yalcin
Mathematics , 2011,
Abstract: Let $G$ be a finite group and $k$ be a field of characteristic $p>0$. A cohomology class $\zeta \in H^n(G,k)$ is called productive if it annihilates $\Ext^*_{kG}(L_{\zeta},L_{\zeta})$. We consider the chain complex $\bPz$ of projective $kG$-modules which has the homology of an $(n-1)$-sphere and whose $k$-invariant is $\zeta$ under a certain polarization. We show that $\zeta$ is productive if and only if there is a chain map $\Delta: \bPz \to \bPz \otimes \bPz$ such that $(\id \otimes \epsilon)\Delta\simeq \id$ and $(\epsilon \otimes \id)\Delta \simeq \id$. Using the Postnikov decomposition of $\bPz \otimes \bPz$, we prove that there is a unique obstruction for constructing a chain map $\Delta$ satisfying these properties. Studying this obstruction more closely, we obtain theorems of Carlson and Langer on productive elements.
Rank Three $p$-Group Actions on Products of Spheres
Ergun Yalcin
Mathematics , 2014,
Abstract: Let $p$ be an odd prime. We prove that every rank three $p$-group acts freely and smoothly on a product of three spheres. To construct this action, we first prove a generalization of a theorem of L\" uck and Oliver on constructions of $G$-equivariant vector bundles. We also give some other applications of this generalization.
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