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Search Results: 1 - 10 of 111841 matches for " Onakpoya O "
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Perception and attitude of people toward onchocerciasis (river blindness) in south western Nigeria
Adeoye A,Ashaye A,Onakpoya O
Middle East African Journal of Ophthalmology , 2010,
Abstract: Background: Onchocerciasis (river blindness) is a major cause of bilateral blindness with devastating socioeconomic consequences. Since Nigeria is the most heavily onchocerciasis endemic country in the world, the information on people′s knowledge about this disease is significant. This could influence their response to current preventive measures of the African Programme for Onchocerciasis Control. Aim: This study was designed to estimate the level of knowledge and attitudes of rural/semi-urban communities in Ife North Local Government Area of Osun State toward onchocerciasis. Materials and Methods: Cluster random sampling was used to select 500 adults for the study. Semi-structured questionnaires were administered to subjects. Data on knowledge of the local name, cause, mode of transmission, manifestation, severity, treatment, and prevention of onchocerciasis were collected and analysed. Statistical analysis included frequency distribution of the responses and a Chi-square test for comparison of variables with the P value for statistical significance set at 0.05. Results: Onchocerciasis was well known by its local name among 458 (91.6%) of the respondents. Only seven (1.4%) knew that it affects both the eyes and skin. The cause was commonly attributed to impure blood by 114 (22.8%), whereas transmission was thought to be through fomites by 161 (32.2%). Only 12 (2.4%) respondents attributed the disease to blackfly bites. The level of education and the association of onchocerciasis with a river were significantly associated (P = 0.001). Subcutaneous nodules were felt to contain water (85.4%), baby worms (3.2%), and fat (0.6%). There was a negative attitude toward sufferers of the disease. Conclusion: Adequate information transfer in simple local dialect by trained personnel to the communities at risk of onchocerciasis is essential for better uptake of all aspects of the onchocerciasis control programme.
The Relationship between Central Retinal Artery Resistive Index and Measures of Renal Function in Type 2 Diabetes  [PDF]
O. O. Ayoola, D. O. Soyoye, S. D. Dawha, R. T. Ikem, O. H. Onakpoya, T. A. Adedeji, F. A. Arogundade
Journal of Diabetes Mellitus (JDM) , 2016, DOI: 10.4236/jdm.2016.62015
Abstract: Background: Renal and ocular vessels are some of the major vessels affected in patients with diabetes, and the involvement of these vessels is independent risk factors for other complications. Hemodynamic flow in arteries may be assessed by using measures such as resistive index, which is a non-invasive measure of the resistance in vessels. The association between retinopathy and nephropathy has been conflicting. This study assessed the relationship between resistive index of the central retinal artery and indices of nephropathy in type 2 diabetes. Method: This cross-sectional study examined 74 Nigerian diabetics who were selected consecutively from the out-patient diabetic clinic of a tertiary hospital in South-West Nigeria. Doppler ultrasound was used to determine the resistive index of the central retinal artery along with the right renal artery. The urinary and serum biochemical parameters were also done to determine the urinary albumin excretion and the glomerular filtration rate. Results: The mean age of participants was 59.62 ± 9.55 years. The mean central retinal artery resistive index (CRARI) was 0.77 ± 0.06, with 65 (87.8%) of the participants having elevated CRARI. There was no statistical difference between patients with normal CRARI and elevated CRARI in respect of their urinary albumin excretion (p = 0.796). There was no significant correlation between CRARI and estimated glomerular filtration rate (r = 0.120; p = 0.309) and right renal artery resistive index (r = 0.068; p = 0.564). Conclusion: This study demonstrates that central retinal artery resistive index (CRARI) may not be a predictor of renal function in diabetics.
Case Report: Fournier\'s gangrene complicating ruptured Richter\'s inguinal hernia
U U Onakpoya, O O Lawal, O D Onovo, F O Oribabor, F O Oribabor
West African Journal of Medicine , 2007,
Abstract:
The prospect of anatomy as a career choice among clinical year medical students in Nigeria
OH Onakpoya, UU Onakpoya, GE Adereti
Annals of African Medicine , 2009,
Abstract: Background : Medical doctors are potential important source of anatomy teachers. The aim of this study was to determine the choice of anatomy as a career option among medical students in a Nigerian medical school Method : Descriptive survey of second- and third-year medical students using a self-administered questionnaire to asses age, sex, perception of anatomy as a subject, anatomy training experience and choice of anatomy as a career among respondents. Analysis was conducted using the SPSS and statistical significance inferred at P<0.05. Results : Three hundred and fifty three (85.3% response rate) who completely filled questionnaire were returned and analyzed of which 195 (55.2%) were males and 158(44.8%) were females. Their ages ranged between 18 and 37 years with a mean of 22.4 9.9 years. Although most students agreed that anatomy was an important subject in medical sciences 346 (98%), they had benefited from anatomy training in their clinical classes 320 (90.7%), and the knowledge of anatomy is useful in investigating patients with certain diseases 251 (71.1%), only 22 (6.2%) would choose anatomy as a career. Male students were more likely to choose anatomy as a career (P=0.026). Textbooks were the most common 334 (94.5%), while radiological means were the least 23 (6.5%) method employed in learning anatomy. Conclusion : Anatomy as a subject is perceived positively by clinical medical students, but the choice as a career option is low; attempt at increasing career interest is needful.
The prospect of anatomy as a career choice among clinical year medical students in Nigeria
Onakpoya Oluwatoyin,Onakpoya Uvie,Adereti Grace
Annals of African Medicine , 2009,
Abstract: Background : Medical doctors are potential important source of anatomy teachers. The aim of this study was to determine the choice of anatomy as a career option among medical students in a Nigerian medical school Method : Descriptive survey of second- and third-year medical students using a self-administered questionnaire to asses age, sex, perception of anatomy as a subject, anatomy training experience and choice of anatomy as a career among respondents. Analysis was conducted using the SPSS and statistical significance inferred at P< 0.05. Results : Three hundred and fifty three (85.3% response rate) who completely filled questionnaire were returned and analyzed of which 195 (55.2%) were males and 158(44.8%) were females. Their ages ranged between 18 and 37 years with a mean of 22.4 9.9 years. Although most students agreed that anatomy was an important subject in medical sciences 346 (98%), they had benefited from anatomy training in their clinical classes 320 (90.7%), and the knowledge of anatomy is useful in investigating patients with certain diseases 251 (71.1%), only 22 (6.2%) would choose anatomy as a career. Male students were more likely to choose anatomy as a career (P=0.026). Textbooks were the most common 334 (94.5%), while radiological means were the least 23 (6.5%) method employed in learning anatomy. Conclusion : Anatomy as a subject is perceived positively by clinical medical students, but the choice as a career option is low; attempt at increasing career interest is needful.
Ophthalmic manifestations in patients with intracranial tumours
O Onakpoya, E Komolafe, F Akintomide, K Ajite, M Komolafe, A Adeolu, S Olateju, A Adeoye, B Adegbehingbe
African Journal of Neurological Sciences , 2009,
Abstract: Introduction L’étude a pour but d’apprécier les manifestations ophtalmologiques des patients présentant des tumeurs cérébrales au Nigéria dans un h pital tertiaire. Méthode Il s’agit d’une étude rétrospective avec une revue des tumeurs cérébrales dans le Neurosurgical Unit of Obafemi Awolowo University Teaching Hospitals Complex, Ile- Ife de janvier 2003 à décembre 2007. L’analyse des données, diagnostique, acuité visuelle, et prise en charge, ont été analysées selon la fréquence en utilisant avec la version 1 11 SPCS . L’acuité visuelle a été classifiée selon celle de l’OMS. Résultat Sur un total de 94 patients, 88 patients ont été revus. Il s’agissait de 53 patients de sexe masculin et 35 de sexe féminin. La moyenne d’age était de 36.2 plus ou moins 20 ans. 14 patients ont été pris en charge par les ophtalmologistes. La répartition des tumeurs était la suivante: méningiomes, 36,4 %, craniopharyngiomes, 13,6 % et gliomes, 9,1 %. 67,9 % des patients se plaignaient de troubles visuels à l’admission dont 46,6 % avec une baisse importante et 12,5 % une vision double. Il a été objectivé une artrophie optique dans 23,9 % . 46 malades (52 %) étaient aveugles et 14 (16 %) avaient un trouble visuel important. Conclusion Les troubles visuels sont des manifestations cliniques fréquentes de présentation des tumeurs cérébrales. Une information médicale précoce est requise.
The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials
Igho Onakpoya,Rohini Terry,Edzard Ernst
Gastroenterology Research and Practice , 2011, DOI: 10.1155/2011/382852
Abstract: The purpose of this paper is to assess the efficacy of green coffee extract (GCE) as a weight loss supplement, using data from human clinical trials. Electronic and nonelectronic searches were conducted to identify relevant articles, with no restrictions in time or language. Two independent reviewers extracted the data and assessed the methodological quality of included studies. Five eligible trials were identified, and three of these were included. All studies were associated with a high risk of bias. The meta-analytic result reveals a significant difference in body weight in GCE compared with placebo (mean difference: kg; 95%CI: , ). The magnitude of the effect is moderate, and there is significant heterogeneity amongst the studies. It is concluded that the results from these trials are promising, but the studies are all of poor methodological quality. More rigorous trials are needed to assess the usefulness of GCE as a weight loss tool. 1. Introduction Overweight and obesity have become a serious health concern [1]. Different weight management strategies are presently utilised, and a variety of weight loss supplements sold as “slimming aids” are readily available. However, the efficacy of some of these food supplements remains uncertain. One such supplement is the green coffee extract (GCE). GCE is present in green or raw coffee [2]. It is also present in roasted coffee, but much of the GCE is destroyed during the roasting process. Some GCE constituents, such as chlorogenic acid (CGA) can also be found in a variety of fruits and vegetables [3]. The daily intake of CGA in persons drinking coffee varies from 0.5 to 1?g [4]. The traditional method of extraction of GCE from green coffee bean, Coffea canephora robusta, involves the use of alcohol as a solvent [5]. Extracted GCE is marketed as a weight loss supplement under a variety of brand names as a weight loss supplement such as “Coffee Slender”, and “Svetol”. Evidence is accumulating from animal studies regarding the use of GCE as a weight loss supplement [6, 7]. In human subjects, coffee intake has been reported to be inversely associated with weight gain [8]. Consumption of coffee has also been shown to produce changes in several glycaemic markers in older adults [9]. Similarly, other research has indicated that the consumption of caffeinated coffee can lead to some reductions in long-term weight gain, an effect which is likely to be due to the known thermogenic effects of caffeine intake as well as effects of GCE and other pharmacologically active substances present in coffee [10]. GCE has also
Childhood eye diseases in southwestern Nigeria: a tertiary hospital study
Onakpoya, Oluwatoyin Helen;Adeoye, Adenike Odunmorayo;
Clinics , 2009, DOI: 10.1590/S1807-59322009001000003
Abstract: background: eye diseases are important cause of medical consultation in children, with the spectrum varying in different localities. this study aimed to determine the spectrum of childhood eye diseases in a tertiary hospital serving rural and semi-rural communities. methods: we conducted a retrospective review of all patients less than 15 years old who presented to the eye clinic of wesley guild hospital ilesa, nigeria between january 2001 and december 2006. data on age at presentation, age at onset of disease, sex and diagnosis were collected and analyzed using spss. a p value less than 0.05 was considered statistically significant. results: we evaluated the reports of 286 children, with a male:female ratio of 1:1.1. children aged 11-15 years made up the largest group (p=0.013). ocular trauma (21.7%), allergic conjunctivitis (17.8%), infections of the eye and its adnexa (15.4%) and refractive errors (14.3%) were the most common conditions. ocular injury was more common in males (p=0.002) and children aged 6-10 years, and 87.1% of these cases were a closed globe injury. infections were seen more commonly among females and children aged 0-5 years, with keratitis representing 40.9% of these cases. congenital eye disease represented 13.3% of childhood eye diseases. conclusion: the prevalent childhood eye diseases recorded here can lead to absenteeism from school and are potentially blinding. health education aimed at the prevention of ocular trauma and prompt presentation for the management of other eye diseases should be encouraged.
The impact of psychological illness on outcome of corrosive esophageal injury
AB Ogunrombi, KS Mosaku, UU Onakpoya
Nigerian Journal of Clinical Practice , 2013,
Abstract: Purpose of Study: Esophageal stricture is a debilitating condition with significant morbidity and mortality, occurring often as a complication of the ingestion of corrosives. In the adult, majority of cases are intentional whilst being accidental in the pediatric population. We therefore sought to describe the circumstances of intentional corrosive ingestion and determine the presence and impact of psychiatric illness on the outcome of management. Materials and Methods: A retrospective analysis of case folders of patients managed with this condition over a ten.year period (2000.2009) was done by comparing sociodemographics and outcome of management in patients with and without psychiatric disorders. Results: Twenty seven cases were reviewed. Mean age was 30.7 (SD =16.01), with a M:F ratio of 1.25:1.86.2% had a diagnosable psychiatric condition, the most common being depression in 55.6% of the patients. Caustic soda (55.6%) was the most common corrosive ingested. There was a significant difference in mean duration before presentation in patients with (1.7 days) and without (6.6 days) previous psychiatric illness (P = 0.01). A significant positive association was also found between surgical outcome and previous history of psychiatric disorder (P = 0.02). Conclusion: Early recognition of psychosocial distress is important to prevent deliberate self.harm. Counter.intuitively, a previous history of psychopathology limits esophageal injury by early presentation and therefore improve chances of a good surgical outcome.
Cataract surgical outcomes in diabetic patients: Case control study
Onakpoya Oluwatoyin,Bekibele Charles,Adegbehingbe Stella
Middle East African Journal of Ophthalmology , 2009,
Abstract: Purpose: To determine the visual outcome of cataract surgery in diabetes mellitus with advanced cataract in a tertiary institution in Nigeria. Design: A retrospective case control study conducted at the University College Hospital, Ibadan Nigeria. Subjects: Twenty three consecutive patients with diabetes and 23 age and sex matched non-diabetic control patients who had extracapsular cataract extraction for advanced cataract between 2002-2005. Main outcome: Mean post operative visual acuity and surgical complications. Results: Twenty three patients with diabetes mellitus and 23 non diabetic controls were studied; mean duration of diabetes was 8.1 ± 7.2 years. The mean post operative visual acuity in diabetics was 0.11±0.38, 0.33±0.57 and 0.38±0.49 at one week, two months and six months compared with 0.23±0.19, 0.46±0.37 and 0.48±0.31 in non diabetics. (p=0.207, 0.403 and 0.465 respectively). Improvement in preoperative visual acuity was noted in 84.2% and 90% in diabetics and non-diabetics respectively. Poor visual outcome in diabetics was mainly due to diabetic retinopathy, maculopathy or diabetes related surgical complications. Conclusion: Visual improvement was seen following surgery for advanced cataract in diabetics in this study population. Post operative monitoring for treatment of diabetic retinopathy may enhance visual outcome.
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