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Search Results: 1 - 10 of 325311 matches for " Okumus S "
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Botulinum toxin injections for blepharospasm prior to ocular surgeries
Okumus S,Coskun E,Erbagci ?,Tatar MG
Clinical Ophthalmology , 2012,
Abstract: Seydi Okumus1, Erol Coskun1, brahim Erbagci1, M Gürkan Tatar2, Aysegul Comez1, Erdal Kaydu1, Ramazan Yayuspayi1, Bulent Gurler11Department of Ophthalmology, University of Gaziantep, 2Ophthalmology Clinic, Nizip State Hospital, Nizip, Gaziantep, TurkeyPurpose: The aim of this study was to show the efficiency of preoperative botulinum toxin A (Botox A) in patients with benign essential blepharospasm who were to undergo ocular surgery with local anesthesia.Materials and methods: Twenty-eight benign essential blepharospasm patients who were administered unilateral Botox A prior to ocular surgery between January 2004 and May 2011 were included in this study. Eleven cases had pterygiums, ten had cataracts, and four had glaucomas, while the remaining three had aphakia. All cases’ severity of spasm (stage 0–4) and eyelid closing forces (stage 1–4) were evaluated according to the Jankovic scale prior to the injection, at 3 days, 14 days, 1 month, and 3 months after Botox A injection.Results: Of the patients enrolled in the study, 16 were female and 12 were male, with an average age of 55.52 ± 1.53 years (52–65). Average onset of the Botox injection's effect was 2.8 ± 0.9 (2–5) days. Its effect lingered for about 11.5 ± 3.6 (8–22) weeks. The severity of spasm and eyelid closing forces of all the patients enrolled were compared prior to the injection at 3 and 14 days and the first and third months after the injection. There were statistically significant differences between prior to the injection and 3 days (P = 0.001), 14 days (P < 0.001) and 1 month after the injection (P <0.001). There was no statistically significant difference between prior to the injection and 3 months after the injection (P = 0.513). Fourteen days following the injection, the surgeries were successfully performed.Conclusion: Botox A administered prior to ocular surgery will control both blepharospasm and lower the risks that can be encountered before and during surgery, thus increasing the comfort of the patient and the surgeon.Keywords: botulinum toxin A, blepharospasm, ocular surgery
Colchicine Induced Heritable Modifications in Leaf Mesophyll Cells of Wheat, (Triticum aestivum L.)
L. Hassan,S.D. Ahmad,A. Okumus,M. Wazuddin
Pakistan Journal of Biological Sciences , 2001,
Abstract: A 3 hr. period treatment with a 0.2% aqueous solution of colchicine was given to one week old seedlings of seven inbred lines of wheat (Triticum aestivum L) plants. Comparisons were made in the CT1 generation between the untreated controls (2x) and colchicine treated plants (C2x) for variation of leaf mesophyll cell size and chloroplast number. Differences were found in that the cell section area and the number of chloroplasts per cell in all the seven lines investigated were significantly greater in the C2x selection compared with the 2x controls using coded determination. Heritable differences were found such that the cell selection areas and the numbers of chloroplasts per cell were significantly greater in the C2x treatment in all the lines. In each case there was an enhancement of chloroplast number independent of the variation in cell size.
Thermal Expansion and Thermal Conductivity Behaviors of Al-Si/SiC/graphite Hybrid Metal Matrix Composites (MMCs)
S. Cem OKUMUS,Serdar ASLAN,Ramazan KARSLIOGLU,Deniz GULTEKIN
Materials Science , 2012, DOI: 10.5755/j01.ms.18.4.3093
Abstract: Aluminum-silicon based hybrid composites reinforced with silicon carbide and graphite particles were prepared by liquid phase particle mixing (melt stirring) and squeeze casting. The thermal expansion and thermal conductivity behaviors of hybrid composites with various graphite contents (5.0; 7.5; 10 wt.%) and different silicon carbide particle sizes (45 μm and 53 μm) were investigated. Results indicated that increasing the graphite content improved the dimensional stability, and there was no obvious variation between the thermal expansion behaviors of the 45 μm and the 53 μm silicon carbide reinforced composites. The thermal conductivity of hybrid composites was reduced due to the enrichment of the graphite component. DOI: http://dx.doi.org/10.5755/j01.ms.18.4.3093
The Direct Regeneration of Maize Haploids Through Anther Culture
L. Hassan,S.D. Ahmad,A. Okumus
Journal of Biological Sciences , 2001,
Abstract: The genetics of plants regenerated from anther-derived callus was investigated using single crosses & inbreds of maize. Anther culture in maize (Zea mays L.) usually follows an indirect procedure involving callus induction and differentiation on at least two different media. Alternatively, development of a direct procedure by which plantlets can be regenerated directly on one medium seems desirable, if acceptable frequency of plant regeneration could be obtained and an effective procedure of chromosome doubling of regenerated plantlets is available. Yupie (YP) and N6 were used as basal media and 10 growth regulators (2,4-D, kinetin, NAA, IAA, IBA, dicamba, pCPA, 6-BA, 2ip and hypoxanthine) were tested to evaluate the feasibility of direct regeneration of haploid plantlets of eight single cross hybrids and four inbred lines. The results indicated that the direct generation of plantlets is feasible through anther culture, though it is genotype and medium dependent. Ten plantlets were regenerated directly from single cross hybrid M60 X M96. The more effective medium was N6 basal medium plus 2,4-D (2.0 mg l-1) and kinetin (1.5 mg l-1). Regeneration frequency (percent of anthers producing plantlets) ranged from 1 to 4%.
Healthy Environments or High Prices? Residents’ Perspective to the Urban Regeneration Projects in Atasehir, Istanbul  [PDF]
Deniz Erdem Okumus, Engin E. Eyuboglu
Current Urban Studies (CUS) , 2017, DOI: 10.4236/cus.2017.54025
Abstract:
Regeneration movement is an irreplaceable necessity for Istanbul not only to prevent the destructions of earthquake and improve physical quality, but also to enhance the quality of life, reduce social vulnerability and maintain both social and physical sustainability. In Turkey, the term of urban regeneration has had different descriptions according to various agencies and stakeholders since 1980s. While academicians evaluate the regeneration projects as planning tools for having sustainable and high quality urban environments from social, ecological and economic approaches, investors for instance justify that they need more development rights and need to make more money to build good condition buildings for having that kind of neighborhoods. Residents, however, are the most important stakeholders to decide the future of the neighborhood. This research aims to evaluate what the residents’ satisfaction level, perceptions and expectations are about the conditions and the possible urban regeneration movements in the neighborhood. 5 main headings are specified as main indicators for the research and conducted by surveys and interviews with current residents in the case of Atasehir, Barbaros Neighborhood which is a new developing and attractive area for real estate investments and urban regeneration projects in Istanbul. At the end of this research, it is stated that residents are very aware of the content of urban regeneration at practice level, and they believe in their neighborhood needs to regenerate for several reasons. They, however, discredit the term about having environment which is healthy and has high quality of life. They are just interested in the economic returns of the projects, and they expect to be built high level income housing to sell the prices out of the market.
Botulinum toxin injections for blepharospasm prior to ocular surgeries
Okumus S, Coskun E, Erbagci , Tatar MG, Comez A, Kaydu E, Yayuspayi R, Gurler B
Clinical Ophthalmology , 2012, DOI: http://dx.doi.org/10.2147/OPTH.S30277
Abstract: otulinum toxin injections for blepharospasm prior to ocular surgeries Original Research (2387) Total Article Views Authors: Okumus S, Coskun E, Erbagci , Tatar MG, Comez A, Kaydu E, Yayuspayi R, Gurler B Published Date May 2012 Volume 2012:6 Pages 579 - 583 DOI: http://dx.doi.org/10.2147/OPTH.S30277 Received: 27 January 2012 Accepted: 12 March 2012 Published: 03 May 2012 Seydi Okumus1, Erol Coskun1, brahim Erbagci1, M Gürkan Tatar2, Aysegul Comez1, Erdal Kaydu1, Ramazan Yayuspayi1, Bulent Gurler1 1Department of Ophthalmology, University of Gaziantep, 2Ophthalmology Clinic, Nizip State Hospital, Nizip, Gaziantep, Turkey Purpose: The aim of this study was to show the efficiency of preoperative botulinum toxin A (Botox A) in patients with benign essential blepharospasm who were to undergo ocular surgery with local anesthesia. Materials and methods: Twenty-eight benign essential blepharospasm patients who were administered unilateral Botox A prior to ocular surgery between January 2004 and May 2011 were included in this study. Eleven cases had pterygiums, ten had cataracts, and four had glaucomas, while the remaining three had aphakia. All cases’ severity of spasm (stage 0–4) and eyelid closing forces (stage 1–4) were evaluated according to the Jankovic scale prior to the injection, at 3 days, 14 days, 1 month, and 3 months after Botox A injection. Results: Of the patients enrolled in the study, 16 were female and 12 were male, with an average age of 55.52 ± 1.53 years (52–65). Average onset of the Botox injection's effect was 2.8 ± 0.9 (2–5) days. Its effect lingered for about 11.5 ± 3.6 (8–22) weeks. The severity of spasm and eyelid closing forces of all the patients enrolled were compared prior to the injection at 3 and 14 days and the first and third months after the injection. There were statistically significant differences between prior to the injection and 3 days (P = 0.001), 14 days (P < 0.001) and 1 month after the injection (P <0.001). There was no statistically significant difference between prior to the injection and 3 months after the injection (P = 0.513). Fourteen days following the injection, the surgeries were successfully performed. Conclusion: Botox A administered prior to ocular surgery will control both blepharospasm and lower the risks that can be encountered before and during surgery, thus increasing the comfort of the patient and the surgeon.
Genetic Variation at Karayaka Sheep Herds Based on Random Amplified Polymorphic DNA Markers
Ahmet Okumus,Levent Mercan
Biotechnology , 2007,
Abstract: Turkish Karayaka sheep breed that is one of the important native breed at Black Sea Region in Turkey was genotyped for 13 RAPD primers. Genotypes of 100 were collected from five different herds (BA, BF, LA, LD and KP herds) localized in the Samsun territory. The genetic similarity was obtained on the dendrograms individuals and herd. Within herds, individuals showed a similarity index between 0.857 to 0.420. The similarity index between populations ranged from 0.520 to 0.710. The binary results also were utilised by principal component analysis for comparison of herds and individuals. The genetic relationship of animals shows a difference among herds in terms of number of RAPD bands. These results show that some herds are effected possibly from other sheep breeds or reared purely such as KP.
Chiasma Frequency and Chromosome Pairing at Tobacco Genotypes (Nicotiana tabacum) in the Middle Black Sea Region
Ahmet Okumus,A. Gulumser
Journal of Biological Sciences , 2001,
Abstract: The study covers the relationship between tobacco genotypes in terms of chromosome homology by pairing configurations and chiasma frequency growing at different areas of the middle black sea region. For this purpose, three genotypes (Samsun, Bafra and Merzifon) and their crosses were studied by acetocarmine stain technique at the stage of metaphase I of meiosis. Consequently, parents and their hybrids showed that bivalent type of chromosome pairing (0.6-1.1 rod type and 22.0-23.4 ring type) and chiasma frequency between 46.90-47.40 %. This type of pairing is considered to be from the close similarity of the chromosomes of genotypes
Genetic Similarity by RAPD Between Pure Lines of Chickens
A. Okumus,M. Kaya
Journal of Biological Sciences , 2005,
Abstract: Twelve primers were used to characterize the genetic similarity among ten chickens which named RIR I, RIR II, Barred I, Barred II, Colombian Rock, Line-54, Blue Line, Maroon Line, Black Line and Brown Line provided by Ankara Poultry Research Institute-Turkey. The objective of this study were to determine PCR-based genetic similarity between lines. Totally, 35 bands were scored for the dendogram prepared on the bases of a similarity matrix using the UPGMA algorithma. The highest and lowest genetic similarities were found to be 0.3773 between Bar I and Maroon and 0.0899 between Col and Bar II, respectively.
The Frequency of Fibromyalgia Syndrome and the Quality of Life in Patients with Peritoneal Dialysis  [PDF]
Muyesser Okumus, Hulya Parpucu, Seher Kocaoglu, Esma Ceceli, Murat Duranay, P?nar Borman
Open Journal of Rheumatology and Autoimmune Diseases (OJRA) , 2012, DOI: 10.4236/ojra.2012.24017
Abstract: ,b>Objective: The aim of this study was to determine the frequency of fibromyalgia (FM) in patients on Peritoneal Dialysis (PD) and to investigate its impact on the quality of life of that population. Methods: A hundred and twenty four patients with end stage renal disease who had undergone PD, and a control group of 54 age and sex-matched healthy volunteers were included to the study. Demographic characteristics including age, sex, disease and dialysis duration were recorded. Fibromyalgia Impact Questionnaire (FIQ) and Nottingham Health Profile (NHP) were also measured. Results: The mean age of the patients (68 female, 56 male) and control subjects (36 female, 18 male) were 43.5 ± 13.4 and 41.2 ± 9.2 years respectively. The prevalence of FM in the PD patients and controls were determined as 9.7% (12 patients) and 11.1% (6 controls) respectively and were found to be similar (p = 0.983). The mean score of sub- groups of NHP except pain and emotion subgroups, were significantly higher in PD patients than in the control group. The mean FIQ levels, the scores of all the subgroups of NHP except the social subgroup were significantly higher in PD patients with FM than in those without FM. Conclusion: In conclusion although the prevalence of FM appears to be similar in PD patients and control subjects, the functional disability is common and quality of life is worse in PD patients with FM than in patients without FM. Detection and treatment of FM may lead to improvement in the quality of life of PD patients with this syndrome.
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