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Search Results: 1 - 10 of 368 matches for " Oberai Chetan "
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Kawasaki disease
Kura Mahendra,Oberai Chetan
Indian Journal of Dermatology, Venereology and Leprology , 2000,
Abstract: Mucocutaneous lymph node syndrome has been rarely seen or reported in India because of its rare occurrence and probably because of its close resemblance to many exanthematous conditions. It is a characteristic disease with a unique clinical presentation. Knowledge about this established disease is essential as it can involve the coronary and other medium and small sized arteries causing vasculitis in about 20% of cases. This probably accounts for a significant number of ischemic heart diseases and sudden deaths in the young, i.e. in the second and third decades, later in life for which no other cause is found then. It is a condition diagnosed entirely on clinical basis and hence the need to be aware of its characteristic features.
Multicenter, open-label, non-comparative study of a combination of polytar and zinc pyrithione shampoo in the management of dandruff
Sawleshwarkar Shailendra,Salgaonkar Viraj,Oberai Chetan
Indian Journal of Dermatology, Venereology and Leprology , 2004,
Abstract: Background: Dandruff is a common condition in clinical practice. We undertook a study to evaluate the efficacy and safety of a combination of zinc pyrithione and polytar in a shampoo base for the treatment of dandruff. Methods: A combination of polytar (1%) and zinc pyrithione (1%) was used for 4 weeks to treat 954 patients suffering from mild to severe dandruff. Scoring of dandruff was done on a 0-10 scale for each of the 6 regions of scalp at weeks 0, 2, 4 and 6. Follow up was for 2 weeks. Results: There was consistent improvement in dandruff scores over the treatment and the follow up period. There was significant improvement in signs and symptoms such as erythema and itching, with a negligible adverse event profile. The global assessment by investigators showed good-excellent results in the majority of patients and there was high acceptability for the treatment among the patients. Conclusion: A combination shampoo of polytar (1%) and zinc pyrithione (1%) offers a safe and effective option in the treatment of dandruff and its associated symptoms.
Natural history of herpes zoster in the era of AIDS
Dandavate Varsha,Hira Subhash,Oberai Chetan
Indian Journal of Dermatology, Venereology and Leprology , 1998,
Abstract: Seventy-four consecutive patients with herpes zoster (HZ) in Mumbai were recruited into the study to determine its natural history. Thirty-five (47.3%) with HZ were infected with HIV-1/2. HZ+HIV+ and HZ+HIV- were demographically similar but HZ+HIV+ were clinically different; the latter were characterised by multidermatomal involvement of thoracic dermatomes below T6 or that of trigeminal nerve, recurrent episodes, bullous lesions and 17/35 had associated illnesses such as severe weight loss, recurrent fever, chronic cough, active tuberculosis and oral candidiasis. Significant differences in the course of healing, incidence of secondary bacterial infection and scaring emerged between the two groups after day-10. HZ+HIV+ individuals had vesicles and ulcers persisting for significantly longer time with frequent sequelae of post inflammatory pigmentation and post herpetic neuralgia. In areas where resources are limited for health information, such clinical differences between HZ+HIV+ and HZ+HIV- will serve to identify individuals with HIV infection in dermatologic clinic. These findings will also be helpful for early diagnosis of HIV infection, associated opportunistic infections and prevent their secondary transmission through appropriate interventions.
A clinical and mycological study of onychomycosis in HIV infection
Surjushe Amar,Kamath Ratnakar,Oberai Chetan,Saple Dattatray
Indian Journal of Dermatology, Venereology and Leprology , 2007,
Abstract: Background: Onychomycosis is one of the early manifestations of HIV infection with a prevalence of 15-40%. Multiple nail involvement, isolation of both common and rare species, and resistance to treatment are the characteristics of onychomycosis in HIV. Aim: To study the epidemiology, clinical manifestations of onychomycosis in HIV-infected individuals and to identify the various causative fungi microbiologically. Methods: A total of 250 HIV infected patients, diagnosed by ELISA, were screened for nail involvement; of which 60 patients i.e., 40 males and 20 females, who had clinically suspected untreated fungal infection were included in this study. Results: Of the 60 respondents, 34 (56.66%) were from the 31-40 years age group. Amongst the 40 males, there were 20 manual laborers and 14 farmers; while 18 of 20 females were housewives. Toenail involvement was seen in 38 patients (63.33%), fingernail in 12 patients (20%) while 10 (16.66%) patients had involvement of both. Twenty eight (46.66%) patients gave history of some trauma, 6 (10%) had diabetes mellitus, and only 1 patient (1.66%) had history of peripheral vascular disease. Nineteen (31.66%) patients had associated tinea pedis, 5 (8.33%) had tinea manuum, 10 (16.66%) had tinea corporis and 7 (11.66%) had tinea cruris. Twenty one (35%) respondents had distal and lateral superficial onychomycosis (DLSO), 5 (8.33%) had proximal subungual onychomycosis (PSO), 1 (1.66%) had superficial white onychomycosis (SWO), while 33 (55%) had total dystrophic onychomycosis (TDO). Fungal elements were demonstrated by KOH mount in 49 patients (81.66%) and growth was seen in 32 (53.33%) cultures. Dermatophytes were isolated in 13 (21.66%) and nondermatophytic molds (NDM) in 19 (31.66%). Out of the 13 positive dermatophyte cultures, Trichophyton rubrum was isolated on 11 and Trichophyton mentagrophytes on 2 cultures. Of the 19 non-dermatophytic cultures, Aspergillus niger was isolated on 3 and Candida spp. on 12 while Cladosporium spp., Scytalidium hyalinum, Penicillium spp., and Gymnoascus dankaliensis on 1 each. Conclusions: Total dystrophic onychomycosis was the most common clinical type and NDM were the predominant causative organisms.
A comparative clinical study of sisomicin cream versus mupirocin ointment in pyodermas
Oberai Chetan,Shailendra S,Dalal Darchan,Patil D
Indian Journal of Dermatology, Venereology and Leprology , 2002,
Abstract: This study was designed to compare the efficacy and safety of sisomicin cream (0.1%) or mupirocin ointment (2%) in the treatment of primary or secondary pyodermas requiring topical antibiotic therapy alone. In the evaluable patients (n=290), impetigo was the commonest clinical condition reported. Staphylococcus aureus was the commonest pathogen isolated from the lesons. Both sisomicin and mupirocin treatments produced a steady improvement in the scores of erythema, oedema, vesiculation, pustulation, crusting and scaling but the improvement produced by sisomicin was quicker and more pronounced. The percentage of patients with complete clearing of all lesions was also higher with sisomicin than with mupirocin on days 4, 8 and 14. Patients subjectively rated the sisomicin formulation as excellent in 75% of cases as against 59% with mupirocin. Sisomicin and mupirocin are effective and safe in the management of pyodermas; however sisomicin therapy resulted in faster and greater relief of signs and symptoms.
A Numerical Approach on Reduction of Young’s Modulus During Deformation of Sheet Metals  [PDF]
Chetan Nikhare
Modeling and Numerical Simulation of Material Science (MNSMS) , 2012, DOI: 10.4236/mnsms.2012.21001
Abstract: The paper investigates the elastic behavior of the metal after unloading. For this purpose the strip of metal with tensile gauge length was simulated with high and low strength material. Further the channel forming was modeled for combination of materials to predict the spring-back and compared the results. It is observed that the Young’s modulus (E-value) decreases with the increase in plastic strain. The strength of the material has no effect on the decrease in the E-value after unloading during tension test. However in channel forming the E-value after unloading depends on the starting E-value, spring-back angle and maximum strain achieved in the channel. The proposed mathematical equations to determine the E-value after unloading from the tension test and channel forming test gives very good prediction with each other. It is also found that the lowest spring-back occurred in the channel with the composite Hard-Soft material.
Pressurization System in Low Pressure Tube Hydroforming  [PDF]
Chetan Nikhare
Modeling and Numerical Simulation of Material Science (MNSMS) , 2013, DOI: 10.4236/mnsms.2013.33009
Abstract: Advanced high strength steels are the group of material with high strength and good formability, because high strength lesser gauge thickness can be used without compromising the function of component. In terms of economic forming process, hydroforming is the manufacturing option which uses a fluid medium to form a component by using high internal pressure. This process gained steep interest in the automotive and aerospace industries because of its many advantages such as part consolidation, good quality of the formed part etc. The main advantage is that the uniform pressure can be transferred to whole projected part at the same time. Low pressure tube hydroforming considered an inexpensive option for forming these advanced high strength steel. This paper investigates the pressurization system used during the low pressure tube hydroforming cycle. It is observed that the usage of ramp pressure cycle during forming the part from low pressure tube hydroforming results in lesser die holding force. Also, the stress, strain and thickness distribution of the part during low pressure tube hydroforming are critically analysed.
Parallel Deformation of the Metals  [PDF]
Chetan Nikhare
Modeling and Numerical Simulation of Material Science (MNSMS) , 2013, DOI: 10.4236/mnsms.2013.33010
Abstract: The metal goes into the plastic deformation after the application of external load. Most of the metal forming industries work on this principle of plastic deformation. Thus the understanding of plastic deformation in the metal forming industry is important. The research on the single material plastic deformation has been carried out from many centuries before the era of Tresca. In this study the two metals 0.05% C steel annealed (soft metal) and 0.6% C steel quenched and tempered (hard metal) were deformed plastically in the parallel combination in the composite form. This study has been carried out with simple mathematical theory and simulated numerical model. The comparison shows the exact match between the mathematical and numerical results. It is also observed that the individual metal thickness affects the deformation flow curve.
Multicenter study to evaluate efficacy and irritation potential of benzoyl peroxide 4% cream in hydrophase base (Brevoxyl) in acne vulgaris
Sawleshwarkar S,Salgaonkar V,Oberai C
Indian Journal of Dermatology, Venereology and Leprology , 2003,
Abstract: In this multicenter, open, non-comparative study, the efficacy and irritation potential of 4% benzoyl peroxide cream in hydrophase base (Brevoxyl) was evaluated for the treatment of acne vulgaris. All evaluable patients (n=567) received treatment with 4% benzoyl peroxide cream in hydrophase base for six weeks. The investigators evaluated the patients at baseline and at 1,2,4 & 6 weeks. Patients also rated their improvement and adverse effects. Doctor′s assessment showed that at the end of 6′h week 85.6% had good to very good effect of the treatment. The profile of side effects observed by doctors revealed that 53.8% of total patients did not have any irritation whereas only 11.6% had moderate to severe irritation. 53.8% of patients did not report any irritation: 41.4% had some irritation whereas only 4.8% patients reported troublesome irritation. A satisfactory response was reported as ear;y as two weeks and most of the patients had a very satisfactory response after six weeks and were willing to continue the treatment. This supports the theory that the hydrophase formulation in ′Brevoxyl helped to enhance efficacy and decrease the irritation associated with use of benzoyl peroxide.
Power Reduction in VLSI chips by Optimizing Switching Activity at Test Process, Architecture & Gate Level
Chetan Sharma
International Journal of Engineering Science and Technology , 2011,
Abstract: Due to increasing the demand of low power VLSI test process, it is necessary to consider all small factors which affect on total power dissipation. This paper gives the reduction of power by advancement in test pattern generation methods and gives the complete flow of data using switching suppression blocks at architecture and gate level.
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