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Search Results: 1 - 10 of 79 matches for " OW Oladejo "
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Sources of cadaver used for dissection at the Ibadan medical school, Nigeria - Analysis of a three-year data
FC Osuagwu, IO Imosemi, OW Oladejo
African Journal of Biomedical Research , 2004,
Abstract: Our experience with cadaver collection at the Department of Anatomy, University of Ibadan, Nigeria between 9th of February 1998 and 11th of October 2001 is presented. A total of twenty-eight bodies were collected from the State Hospital, Ring Road during this period viz: twenty-six were males (92.9%) and two females (7.1%). Twenty-two (78.6%) were suspected bandits who died during gun duel with law enforcement agents while six (21.4%) were bodies that were accident victims and unclaimed bodies. Four of the unclaimed bodies were males (66.7%) while females were two (33.3%). The majority of bodies that were those of suspected bandits were males and they were twenty-two (100%) while no female (0%) was recorded. No record of voluntary donation of cadavers for anatomy dissection was documented. Adequate documentation is advocated for the giving hospital and the receiving medical school. It is suggested that anatomists embark on a more aggressive enlightenment campaign to the society to encourage those that might be willing to voluntarily will their body after dying to further the quest of knowledge to do so.
Enhanced wound contraction in fresh wounds dressed with honey in wistar rats (Rattus novergicus)
FC Osuagwu, OW Oladejo, IO Imosemi, A Aiku, OE Ekpo, AA Salami, OO Oyedele, EU Akang
West African Journal of Medicine , 2004,
Abstract: Background: Due to reports that honey accelerates wound healing, an investigation on its role in wound contraction in fresh wounds inflicted on wistar rats was carried out. Method: Twenty adult male wistar rats had 2cm by 2cm square wound inflicted on their right dorsolateral trunk. They were divided into two groups. The experimental group had their wounds dressed with honey while the control group had normal saline dressing. Wound dressing was done every five days and measurements taken at each dressing. Wound morphology was also assessed. Results: Dressing with honey significantly enhanced percentage wound contraction on day 10 with value of 79.20 ± 2.94 compared to control value of 53.50 ±4.32. p=0.0. The mean wound measurement on day 10 reduced significantly in honey group, 1.15±0.18 compared to control group 2.38 ± 0.28. p=0.002. However, there was no significant difference in fibroblast count per high power field in honey group 68.0 ±2.59 compared to control 90.2 ± 17.40, p=0.242. Honey dressing increased mean blood vessel count per high power field, 18.8±3.77 albeit non significantly when compared to control value of 13.4±2.44, p=0.264. Also honey dressing caused increased granulation tissue formation in wounds dressed with honey compared to control group. Conclusion: Our study suggests that honey dressing enhances wound contraction in fresh wounds which is one of the key features of wound healing. Key Words: Wound contraction, Honey, Healing. Résumé Introduction: D\'après des rapports que la consommation du miel accélere la cicatrisation de blessure, une enquête sur son effet en matiére du reserrement en ce qui concerne une plaie récente fait aux wister rats a été effectuée. Méthode: On a fait une plaie de 2cm par 2cm carré dans le c té droit du trompe des vingt wistar rats du sexe masculin adultes. On a divisé ces rats en groupe de deux, et on a soigné le groupe d\'experimentation avec le miel tandis que le groupe du contr le était traité normalement avec le goutte-à-goutte de solution saline . On fait un pansement tous les cinq jours et on prend les mesures pendant chaque pansement. On a également évalué la morphologie de la blessure. Resultats: Le pansement avec le miel a remarquablement amélioré le pourcentage du resserrement de la plaie pendant le dixième jour avec la valeur 79,20 ±2.94 par rapport à la valeur du groupe du contr le de 53,50 ± 4.32 P =0,0 Le moyen de la mesure de la plaie dans le dixième jour était remarquablement en basse dans le groupe du miel, 1,15±0.18 par rapport au groupe du contr le 2,38 ± 0.28, P=0,002. Toutefois, il y a aucune difference importante en matière du compte fibroblast par high power field dans le groupe du miel 68,0 ± 2,59 par rapport au groupe du contr le 90,2 ± 17,40, P= 0.242. Le pansement avec du miel a augmenté le moyen du compte du vaisseau sanguin par power field élevé dans le groupe du miel 18,8±3,77 albeit non important par rapport à la valeur du contr le de 13,4 ± 2.44 P = 0,264. En plus
Histomorphometric studies on the effect of cyanide consumption of the developing cerebellum of wistar rat (Rattus novergicus)
AO Malomo, IO Imosemi, FC Osuagwu, OW Oladejo, EEU Akang, MT Shokunbi
West African Journal of Medicine , 2004,
Abstract: Objective: To investigate the microscopic effect of maternal cyanide consumption on the developing cerebellum of Wistar rats. Materials and methods: Twenty pregnant female rats weighing between 160 g and 180 g were used in this study. The rats were separated into two groups comprising ten control and ten experimental animals. The control animals were fed a standard diet of mice cubes, while the experimental animals were fed 500 ppm potassium cyanide, mixed with the standard diet. The diets were fed to the animals and their litters in separate cages and water provided ad libitum during pre and postnatal life. After birth, the offspring (five per group) of days 1,9, 14, 21, 28 and 50 were weighed and killed by cervical dislocation. The cerebellar tissues were processed and microscopic parameters studied. Results: A thicker external granular layer (EGL) was seen in the control group on day 1(39±9.2mm) compared with the experimental group (29±5.8mm) and on day 9(83± 7.1mm) compared with the experimental group (78± 13mm). However, these were not significantly different statistically. A thicker and persistent EGL was observed in the experimental group on days 14 and 21. A significant (P<0.05) reduction in the thickness of molecular layer (ML) was observed on days 28 and 50 in the experimental group. The density and size of the Purkinje cells were the same in both the control and experimental groups (P>0.05). Conclusion: Maternal consumption of 500 ppm cyanide in rats does not significantly affect light microscopic prenatal cerebellar development, but causes mild changes in the post-natal life. Maternal cyanide consumption causes delayed maturation of the cerebellum, as evidenced by the thicker EGL, and reduction in the ML in the experimental group which become noticeable only at about 28th day of postnatal life. Key Words: Cyanide, Diet, Development and Cerebellum Résumé Objectif: Etudier les effet microscopiques de la consommation cyanure maternelle sur le developpement du cervelet des rats Wistar Matériels et Méthodes: Vingt rats sexe féminin pleine pesant entre 160g et 180g ont été utilisés dans cette étude. Les rats ont été séparés en deux groupes comprend dix controle et dix animaux experimentaux. Les animaux du controle ont été nourri avec des alimentations complètes composées de morceau de viande des souris, tandis que les animaux expérimentaux ont été nourri de 500 ppm de cyanure de potassium, melangé avec une alimentation complète. Les alimentations ont été données aux animaux et leur litières dans des cages séparées, de l\'eau a été fourni ad libitum pendant la vie pré et postnatale. Après naissance; des descendants (cinq par groupe) des jours 1,9,14,21,28,et 50 ont été pésés et tués à travers la dislocation cervicale. On avait examiné les tissu nerveux et on avait également étudié les paramétres microscopiques. Resultats: La couche extérieure granulaire épaisse (CEG) était vue chez le groupe de controle pendant le premier jour (39± 9,2 Um) p
Enhancement of cutaneous wound healing by methanolic extracts of ageratum conyxoides in the wistar rat
OW Oladejo, IO Imosemi, FC Osuagwu, OO Oluwadara, A Aiku, O Adewoyin, OE Ekpo, OO Oyedele, EEU Akang
African Journal of Biomedical Research , 2003,
Abstract: In a bid to test the wound healing effect of a crude methanolic extract of Ageratum conyzoides (Linn.), 20 animals were divided into two groups of ten animals each representing control and experimental groups. Each animal had a 2cm x 2cm area of skin on the right dorsolateral flank area marked and excised. The resulting area of skin wound in the experimental group was dressed with crude methanolic extract of Ageratum conyzoides at a five daily interval while the animals in the control group were dressed with normal saline at the same interval. The wound area was measured at the tenth post-operative day for animals in both groups and the percentage wound contraction calculated. Sample of granulation tissues and end scar obtained from these animals and prepared by routine paraffin wax method. Fibroblast and blood vessel counts were determined in both groups. The result showed a significant increase in the percentage wound contraction at day 10 in the experimental group compared with the control (82.3 ± 1.6 % vs 55.0 ± 4.2 %), P < 0.05. The wound of animals in both groups showed excellent granulation tissue formation and minimal signs of wound infection. There was a significant reduction in the mean fibroblast count in the experimental group compared with the control (44.2 ± 5.8/ high power field vs 90.2 ± 17. 4 / high power field),P < 0.05. The exact significance of this cannot however be determined. There was no significance difference in the vessel count. It was concluded that extract of Ageratum conyzoides has a better wound healing enhancing action compared with normal saline treated controls. This effect may be due to the antimicrobial properties of Ageratum conyzoides
Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) - approach to diagnosis and managment
AO Oladejo
Annals of Ibadan Postgraduate Medicine , 2009,
Abstract: No abstract
Overview of the Metabolic Syndrome; An Emerging Pandemic of Public Health Significance
AO Oladejo
Annals of Ibadan Postgraduate Medicine , 2011,
Abstract: A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together have become known as the metabolic syndrome. Over the years various diagnostic criteria have been proposed by different organizations and most recently efforts have been made to unify the diagnostic criteria. This article is aimed at providing an overview of the metabolic syndrome and a rational approach to the management of this very important clinical syndrome.
Problems in estimating material effects
OW Robinson
Genetics Selection Evolution , 1980, DOI: 10.1186/1297-9686-12-1-115b
Problems in estimating material effects
Robinson OW
Genetics Selection Evolution , 1980,
L sst sich die lukrative Therapie des lokalisierten Prostatakarzinoms verbessern?
Hakenberg OW
Journal für Urologie und Urogyn?kologie , 2008,
Review: Current Trends in the Diagnosis and Management of Globus Pharyngeus  [PDF]
Scott Mitchell, Oladejo Olaleye, Matthew Weller
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2012, DOI: 10.4236/ijohns.2012.13013
Abstract: Aim: To review recent literature on the diagnosis and management options for globus pharyngeus. Recent Findings: Strong evidence for the cause of globus pharyngeus is lacking however there is some research to suggest a possible link between laryngopharyngeal reflux (LPR) and globus pharyngeus. Radiological investigations used to find the cause of globus pharyngeus are often normal with little evidence to support their routine use. There are no long term controlled studies investigating the effectiveness of proton pump inhibitors (PPI’s) for the treatment of globus pharyngeus however, these are commonly used. A recent nonplacebo-controlled study has shown promising results using liquid alginate suspension to treat laryngopharyngeal reflux symptoms. Other treatment modalities used, such as speech and language therapy, have shown some improvement in symptoms but these are often small trials. Summary: Globus pharyngeus is a clinical diagnosis. Investigations should be reserved for those with atypical symptoms. Thorough clinical evaluation and examination, including fibreoptic laryngoscopy, are key points in management.
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