OALib Journal期刊

ISSN: 2333-9721



匹配条件: “OMOYA” ,找到相关结果约5条。
Antifungal Activities of a Pasture Honey and Ginger (Ziginber Officinale) Extracts on Some Pathogenic Fungi
FO Omoya
Journal of Science and Technology (Ghana) , 2012,
Abstract: Methanol, ethanol, ginger extracts and a pasture honey were tested on Aspergillus flavus, Aspergillus fumigatus, Trichoderma viride and Candida albicans using the well-in-agar method. The antifungal sensitivity assay indicated that the chemical solvent extracts of ginger, pasture honey and mixtures of honey and ginger extracts exerted inhibitory zones on the test fungi species except A. Fumigatus. However, the pasture honey displayed higher inhibitory values of 45 mm than the mixtures of honey and ethanol extract of ginger and honey and methanol extract of ginger with 40 mm and 30 mm inhibitory zones respectively. The phytochemicals present in honey were saponin and cardiac glycoside, while in the ginger sample, saponin, phlobatannin, alkaloids, flavonoids and cardiac glycoside were present. Summarily, honey and ginger extracts displayed the highest inhibitory activity on all the tested fungal isolates compared to the employed positive control antifungal (Griseofulvin and Ketoconazole).
Mixture of honey and ginger extract for antibacterial assessment on some clinical isolates.
International Journal of Pharmaceutical and Biological Research , 2011,
Abstract: The antibacterial activity of honey, methanol and ethanol extracts of ginger (Zingiber officinale) were investigated against some selected bacteria using the agar diffusion technique. Two Gram positive and four Gram negative bacteria were assessed for possible inhibition by the extract samples. The inhibitory potency of the extracts on the test organisms varied in the halos as inhibition effects. Though all the test organisms were susceptible to the antibacterial samples with inhibition measure between 6-3mm, E. coli was the most inhibited where an inhibitory measure of 20mm was recorded with honey, 18mm with ginger ethanol extract and 32mm with the mixture of honey and ginger ethanol extract. The pasture honey, the ethanol and methanol extracts of ginger were both positive for saponin and cardiac glycosides among the phytochemicals identified. While some of the commercial antibiotics (positive control) were not effective on the test organisms, gentamycin and streptomycin were effective with inhibitory halos ranging between 8-25mm. However, the antibacterial test samples were higher in inhibition values than the reference drugs (positive control).
Synergistic Effect of Combined Antibiotics against Some Selected Multidrug Resistant Human Pathogenic Bacteria Isolated from Poultry Droppings in Akure, Nigeria  [PDF]
Funmilola Oluyemi Omoya, Kehinde Oluyemi Ajayi
Advances in Microbiology (AiM) , 2016, DOI: 10.4236/aim.2016.614100
Antibiotic resistant bacteria pass between humans, between animals and between humans and animals in both directions, the use of antibiotics in poultry has contributed to multiple antibiotic resistant in pathogenic bacteria and use of two antibiotics might prevent the emergence of resistance to either. In this study, synergistic effect of combined antibiotics against multidrug resistant human pathogenic bacterial isolates from poultry droppings in Akure, Nigeria was examined. Collection of samples, isolation and identification of bacteria were carried out using standard microbiological method, antibiotic sensitivity test was performed by disc diffusion method and zone of inhibition was used to interpret the sensitivity test as resistant, susceptible or intermediate while combined effects of two antibiotics were investigated by macrobroth dilution and checkerboard assay methods while the synergetic effects of combined antibiotics were calculated using Fractional Inhibitory Concentration (FIC) and percentage synergistic interaction was calculated. All the ten (10) species of bacterial isolates were multidrug resistant and are less resistant to ofloxacin. The highest percentage synergistic interactions observed were Ofloxacin + Amoxicillin (90%), Ciprofloxacin + Amoxicillin (90%), Tetracycline + Amoxicillin (70%), Tetracycline + Augmentin (80%), Cotrimoxazol + Amoxicillin (50%), Cotrimoxazol + Augmentin (70%), Chloramphenicol + Amoxicillin (70%) and Chloramphenicol + Augmentin (80%). Poultry droppings is a potential source of human pathogenic bacteria, high frequency of multiple antibiotic resistance bacteria observed in this study is of great treat to man as this may cause the treatment of infection caused by these bacteria to be difficult. Combination of beta-lactam antibiotic with fluoroqunolones, tetracycline, Chloramphenicol and Cotrimoxazole was synergetic and this will reduce dose related toxicity and prevent resistance to single antibiotic.
2. Evaluation of larvicidal potency of some entomopathogenic bacteria isolated from insect cadavars on Anopheles arabiensis larvae in Nigeria
F.O. Omoya,F.A. Akinyosoye
International Journal of Pharmaceutical and Biomedical Research (IJPBR) , 2011,
Abstract: The laboratory evaluation of larvicidal activities of some bacteria namely; Pseudomonas aeruginosa, Bacillus polymyxa and Bacillus subtilis was assessed against the second and fourth instar of Anopheles arabiensis collected from South West Nigeria. Concentrations ranging from 1.3 X107cfu/mL to 6.5 X 107cfu/mL were tested on the larvae for a period of 48 h. The disparity in the activities was monitored with Bacillus subtilis displaying the highest activity in both the second and fourth instar with LC50 of 0.865 and 2.361 mg/mL respectively. Pseudomonas aeruginosa showed LC50 of 1.931 and 4.205 mg/mL while the least activity was recorded in Bacillus polymyxa with LC50 of 5.776 and 7.403 mg/mL. There were significant differences in the LC50 value of the bacteria on tested instars. Values obtained from the fourth instar group were significantly different from those obtained from the second instar group in all the treatments. Finding from this study showed that B. Subtilis may be a potential biocontrol agent of Anopheles arabiensis, the main malaria vector in Nigeria.
Mosquito-Degradative-Potential of Cockroach and Mosquito Borne Bacteria
F.O. Omoya,B.E. Boboye,F.A. Akinyosoye
Journal of Medical Sciences , 2009,
Abstract: The type of bacteria present on two insects (cockroach and mosquito) were investigated. These microorganisms were screened for microbial control of mosquito employing their degradative ability at various microbial cell loads. The degradation of the mosquito was observed spectrophotometrically for an incubation period of 5 to 7 days. Six bacterial species (Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, Serratia marcescens, Staphylococcus aureus and Aerobacter aerogenes) were isolated from cockroach. Mosquito borne E. coli, P. aeruginosa, B. cereus and Staph. aureus. All the bacteria digested the mosquito with activity ranging from 0.02 to 1.27. Microorganisms associated with cockroach showed higher degradation activity (0.02-1.27) during the incubation than those obtained from mosquito (0.02-1.00).

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