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Search Results: 1 - 10 of 573 matches for " OA Ashaye "
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Effect of gamma irradiation on moisture sorption isotherms of cowpeas
OA Ashaye
African Journal of Biotechnology , 2006,
Abstract: The effect of gamma irradiation on moisture sorption isotherms of cowpeas was investigated The nonirradiated and irradiated cowpeas exhibited the typical three stage sigmoidal curve found in most foods. There was also a concomitant increase in the equilibrium moisture content (EMC) as relative humidity increased for non- and irradiated cowpeas. Drum cowpea (15 Gy) had the highest rate of water absorption. Generally, the amount of water absorbed by irradiated cowpeas is generally higher than non-irradiated cowpeas.
Modified Bare Sclera method for the treatment of primary pterygium: A preliminary report
AO Ashaye
West African Journal of Medicine , 2005,
Abstract: Introduction: The bare sclera technique is still in use by many surgeons worldwide in spite of the attendant high recurrence rate. Any modification of this well known procedure may be more widely acceptable if associated with lower recurrence. Method: The bare sclera technique was modified by performing a partial thickness sclerectomy from the pterygium bed. This modified technique was applied to 23 eyes of 17 patients with primary pterygium. The subjects were followed up for varying periods between 8 to 31months to determine the recurrence rate of pterygium after surgical excision and other complications. Results: Initial observation showed that the recurrence occurred in two eyes of two patients of a series who were followed up for a minimum of six months and up to thirty-one months. Two other eyes developed suture granuloma. There were no other complications observed in the remaining twenty eyes of fifteen patients. Conclusion: Partial thickness sclerectomy when performed with standard bare sclera technique seems promising and may improve the results of pterygium excision by bare sclera method.
Presumed hereditary retinal degenerations: Ibadan experience
AO Ashaye
West African Journal of Medicine , 2005,
Abstract: Background: Retinitis pigmentosa (RP) is a hereditary retinal degenerative condition with no known treatment. Associated ocular conditions, such as cataract and glaucoma, when present further worsen vision, but these conditions are often treatable. There are, however, no known reports of cataract or glaucoma surgery in subjects with RP in Nigeria. This study describes the clinical presentation of RP, the prevalence of associated treatable disorders and the characteristics of patients with severe visual impairment and blindness. Method: A retrospective review of 52 cases presumed and diagnosed to have RP was performed on patients who presented at the Eye Clinic, University College Hospital, Ibadan over a three-year period. The cases were classified into clinical types; those with associated treatable eye conditions were identified and those with severe visual impairment and blindness were further evaluated. Results: Retinitis pigmentosa was an uncommon clinical condition in patients who presented at the Eye Clinic being 0.69% (n = 52) of a total of 7,520 new outpatients recorded during a 3-year period. Typical RP were 44 in number representing 84.0% of these cases. Those diagnosed with very early onset RP, with severe visual impairment and nystagmus may have been congenital Leber's amaurosis. Retinitis pigmentosa with systemic features and atypical RP were uncommon. However, 34.5% had cataract (mostly posterior subcapsular cataract), while 11.4% had high intraocular pressure and these were mostly in couched eyes. Risk factors for severe visual disability and blindness were cataract, age and secondary glaucoma as a result of couching. Conclusion: Treatable ocular conditions associated with RP are not uncommon. RP patient tend to have cataract which if neglected may result in total blindness.
Traumatic Hyphaema: A report of 472 consecutive cases
Adeyinka O Ashaye
BMC Ophthalmology , 2008, DOI: 10.1186/1471-2415-8-24
Abstract: Retrospective case analysis of 472 patients with traumatic hyphaema admitted to the University College Hospital, Ibadan between January 1997 and December 2006.The home was the single most frequent place of injury for all cases and for 75% of cases in children aged 0–10 years. Injuries that occurred at school comprised about one-fifth of cases. Sport-related injuries were uncommon.The most common activities preceeding injuries were play, corporal punishment and assault. Stones, sticks and whiplash were the agents that caused traumatic hyphaema. Occupational-related hyphaema that caused injuries was mostly in farmers and artisans, few of whom used protective goggles. The majority of patients were males. Children and young adults aged ≤ 20 years comprised 63.6% of patients. A total of 336 (76%) eyes had at least one surgical intervention. While 298 (73.2%) patients had visual acuity (VA) less than 6/60 at presentation, 143 (37.0%) of eyes had visual acuity (VA) < 6/60 3 months after injury.The injuries leading to traumatic hyphaema occur mostly at home and school, and frequently affect children and young adolescents. Over one-third resulted in blindness in the affected eye. The focus should be on prevention of stick-related eye injuries at these locations and improving access to eye health services for patients who sustained eye injuries.The eyes are the third most common organs affected by injuries, next to the hands and feet [1], despite the fact that they represent only 0.27% of the total body area and 4% of the facial area. Eye injuries still remain one of the most common causes of unilateral blindness worldwide. Blunt eye injuries mostly result in traumatic hyphaema and are not an infrequent cause of presentation to the emergency units of many eye clinics [2-8]. Most result from unnecessary eye injuries, which are largely preventable.Although eye injuries are a major public health problem globally, most studies have come from developed countries. Reports from deve
Combined central retinalartery and vein occlusion complicating orbital cellulitis
OO Komolafe, AO Ashaye
Nigerian Journal of Clinical Practice , 2008,
Abstract: Orbital Cellulitis is a dreaded ophthalmologic disease. Itmay destroy vision and the eye andmay even become life threatening. Often visual loss is the result of exposure and subsequent destruction of ocular tissue commonly the cornea and the uvea. We report a case of combined central retinal artery and vein occlusion complicating orbital cellulitis in a 35 year old patientwho was 37 weeks pregnant resulting in loss of vision in the affected eye. There have been fewcase reports of this type of complication of orbital cellulitis.
Ocular findings seen among the staff of an institution in Lagos, Nigeria
AO Ashaye, MC Asuzu
West African Journal of Medicine , 2005,
Abstract: Background:The degree to which ocular morbidity affects workers productivity in the developing countries has not been studied adequately. A federal government research institute based in Lagos introduced an annual health screen for all its workers, which included eye tests. This provided an opportunity to study the pattern of ocular conditions among workers who were 30 years and above, and to determine the effect of eye diseases on the workers productivity. Study design: Detailed eye examination including refraction, was done on every respondent at the institution\'s clinic by an ophthalmologist. A questionnaire on ocular health status and occupational history was administered independently by an ophthalmic nurse. Sickness absenteeism, use of the clinic were obtained from clinic records, and the results were analysed. Results: The common ocular conditions were uncorrected or poorly corrected refractive error, uncorrected or poorly corrected presbyopia and allergic conjunctivitis. Glaucoma, maculopathy and optic atrophy were causes of severe visual impairment or blindness in 1.9% of the subjects. Absenteeism and clinic use were more common in subjects with ocular morbidity than those with non-ocular morbidity. Subjects with ocular morbidity had more illnesses, absenteeism and used the clinic more. Conclusion: Ocular problems which reduce worker\'s productivity are prevalent among the staff of the institution studied. They are mostly unrecognised.
Wound dehiscences following cataract surgery in children: a report of seven cases
AO Ashaye, BA Olusanya
Nigerian Journal of Paediatrics , 2006,
Distal Renal Tubular Acidosis, an Uncommonly diagnosed Cause of Failure to Thrive: Report of Five Cases.
OA Ajayi, OA Mokuolu
Nigerian Journal of Paediatrics , 2001,
Abstract: Five cases of distal renal tubular acidosis aged between 2 weeks and 2 months are described. The presenting features included lethargy, refusal to feed, high density of periodic respiration, vomiting and recurrent episodes of unexplained metabolic acidosis. A constant feature was failure to thrive despite caloric intakes in excess of normal requirements. The diagnosis of distal renal tubular acidosis (DRTA) was based on a urine pH>5.5 in a freshly voided urine despite concurrent or induced metabolic acidosis. All the babies responded dramatically to sodium bicarbonate supplement, as baking soda or bicarbonate of soda. The need for increased index of suspicion of DRTA in the evaluation of children in early infancy for failure to thrive and the simplicity of treatment using baking soda is discussed. Nigerian Journal of Paediatrics 2001; 28:21. pp. 21-24
Prion biology and bovine spongiform encephalopathy
Archivos de medicina veterinaria , 2011, DOI: 10.4067/S0301-732X2011000200002
Abstract: the complex nature of prions has intrigued the scientific community during the last 70 years. since the first indication of scrapie infectivity and the experimental transmission of the scrapie agent in 1937, prions and their associated transmissible spongiform encephalopathies (tses) have been under constant investigation. tses are neurodegenerative and fatal diseases with no early diagnosis, treatment or cure. despite their diverse presentations, all tses stem from the infectious, spontaneous or hereditary conversion of the host-encoded cellular prion protein prpc into the pathogenic isoform prpsc. based on the prion hypothesis, prpc has the autocatalytic or induced capacity to change its secondary configuration from a mainly α-helix structure into predominant β-sheet configuration. another enigmatic aspect of the prion biology is the potential physiological function of prpc, a protein that is widely distributed in mammalian tissues and intensely expressed in the nervous system. prpc has been associated to several biological roles including cellular adhesion, protection and differentiation. the unpredictable properties of the prpsc and the complex presentation of tses have opened many questions yet to be answered. the potential zoonotic transmission of the bovine spongiform encephalopathy (bse) has generated intense concern in the international community over animal product biosecurity. during the last years, research in prion biology has mainly focused on determination of the pathogenesis of tses and the development of diagnostic and therapeutic methods. however, further research in prion biology is required in order to understand the complex nature of tses and how these diseases can be controlled.
Climate impacts, forest-dependent rural livelihoods and adaptation strategies in Africa: A review
OA Somorin
African Journal of Environmental Science and Technology , 2010,
Abstract: The long term contribution of forests to the livelihoods of the rural poor had been long appreciated. More than half of Africa’s fast-growing population rely directly and indirectly on forests for their livelihoods. As the continent faces stresses from poverty and economic development, another major uncertainty is looming that could alter many of the relationships between people and forests. This uncertainty is climate change. Climate impacts such as changes in temperature and rainfall patterns resulting in drought, flooding, all exert significant effect on forest ecosystems and their provision of goods and services, which form the safety nets for many African rural poor. Building adaptation strategies becomes an option for forest-dependent households and communities, and even countries whose economies largely depend on the related sectors. The review details cases of impacts, underlying causes of vulnerability, and identified coping and adaptation strategies, as reported in their National Communications by many African countries to the United Nations Framework Convention for Climate Change.
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