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Search Results: 1 - 10 of 152591 matches for " Norma T Gross-Martínez "
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Agentes etiológicos de onicomicosis diagnosticadas en el laboratorio de micología médica de la Universidad de Costa Rica
Salas-Campos,Ingrid; Gross-Martínez,Norma T;
Acta Médica Costarricense , 2012,
Abstract: background and aim: among the onychodistrophies, onychomycosis are the most frequently encountered. this infection not only constitutes an esthetic problem for the patients, but can also affect their daily activities. for dermatologists, it is crucial to make a differential diagnosis; thus, the medical mycology laboratory plays an important role to achieve this purpose. the fungal agents most frequently encountered are the dermatophytes, however, other filamentous non-dermatophyte fungi have been isolated and are known to be less susceptible to antifungals. in the present work, the frequency of onychomycosis among patients attending the medical mycology laboratory, ucr, was studied during four years, according to the age and sex of the patients, as well as the isolated etiological agents identified. methods: the study included all patients that requested the community service provided by the department of medical mycology, school of microbiology, ucr, between january 2007 and december 2010 and that showed nail alterations suspicious for onychomycosis. the age and sex of each patient were registered and samples were processed for direct microscopy and culture. results: a total of 431 nail samples were collected, of which 85.4% were toenails and 14.6% fingernails. the mean age of the patients was 49 years, of which 64% were females and 36% males. onychomycosis was diagnosed, either by direct microscopy and culture, or only with positive direct microscopy, in 73.4% of the sample population, of which 89.4% were toenails and 10.6% fingernails. trichophyton rubrum was the etiological agent most frequently isolated from toenails, followed by fusarium spp. c albicans was the most frequent fungal agent observed in fingernails. conclusion: the diagnosis of onychomycosis relies upon both the clinical and laboratory diagnosis. dermatophytes, yeasts and non-dermatophyte filamentous fungi were identified in the population studied. these findings should be considered due to their
Agentes etiológicos de onicomicosis diagnosticadas en el laboratorio de micología médica de la Universidad de Costa Rica Etiological agents of onychomycosis diagnosed in the medical mycology laboratory of the University of Costa Rica
Ingrid Salas-Campos,Norma T Gross-Martínez
Acta Médica Costarricense , 2012,
Abstract: Justificación y objetivos: Entre las onicodistrofias, la onicomicosis es la afección más frecuente. Esta infección no solo representa un problema estético para el paciente, sino que puede afectar sus actividades diarias. Para el dermatólogo se hace indispensable realizar el diagnóstico diferencial, por lo que el laboratorio de micología médica es de gran ayuda para este propósito. En cuanto a los agentes etiológicos incriminados, los dermatofitos son los más frecuentes; sin embargo, otros hongos filamentosos no dermatofitos se han aislado, cuya sensibilidad a los antimicóticos es menor. En este trabajo se estudió la frecuencia de las onicomicosis diagnosticadas en el laboratorio de Micología Médica de la UCR durante cuatro a os, según edad y sexo de los pacientes, así como agentes etiológicos identificados. Métodos: Se incluyó a todos los pacientes que solicitaron el servicio de acción social que brinda la sección de Micología Médica, Facultad de Microbiología, Universidad de Costa Rica, entre enero del 2007 a diciembre del 2010 y que presentaban alteraciones ungueales sospechosas de onicomicosis. Se registró la edad y sexo de los pacientes y las muestras se procesaron por examen directo y cultivo. Resultados: Se procesaron 431 muestras de u as, el 85,4% eran de pie y el 14,6% de mano, la edad promedio de los pacientes fue de 49 a os, el 64% eran mujeres y el 36% eran hombres. En el 73,4% se diagnosticó onicomicosis, ya sea por examen directo positivo y cultivo positivo, o solo con el examen directo, de las cuales 89,4% eran u as de pie y 10,6% u as de manos. De las u as de los pies se aisló más frecuentemente Trichophyton rubrum y en segundo lugar Fusarium spp. En u as de manos C. albicans fue el agente etiológico más frecuente. Conclusión: En el diagnóstico de las onicomicosis se debe considerar tanto la clínica como los hallazgos de laboratorio. En la población estudiada se identificaron dermatofitos, levaduras y hongos filamentosos no dermatofitos, lo que es importante tener en cuenta por las implicaciones en la elección del tratamiento. Background and aim: Among the onychodistrophies, onychomycosis are the most frequently encountered. This infection not only constitutes an esthetic problem for the patients, but can also affect their daily activities. For dermatologists, it is crucial to make a differential diagnosis; thus, the medical mycology laboratory plays an important role to achieve this purpose. The fungal agents most frequently encountered are the dermatophytes, however, other filamentous non-dermatophyte fungi have been isolated and are kno
Micosis superficiales diagnosticadas en el laboratorio de micología médica de la Universidad de Costa Rica
Salas-Campos,Ingrid; Gross-Martínez,Norma; Carrillo-Dover,Pedro;
Revista Costarricense de Ciencias Médicas , 2007,
Abstract: superficial mycosis is a frequent cause of consultation in dermatology and general medicine. the microbiological studies of this fungal condition are important not only to do the differential diagnosis, but also to establish the causing agent of the disease as well as its epidemiological aspects and the treatment. in this study 265 skin and nail samples have been collected from individuals at the laboratory of medical mycology of school of microbiology, costa rica university. nail diseases represent 67,5% of the total cases studied. trichophyton rubrum was the most frequent isolated fungus; also, other dermatophytes and candida sp. were isolated from nail and skin. fusarium sp., a filamentous nondermatophyte fungus, was isolated from both finger and toe nails. this finding is of relevant, since fusarium sp., an emergent etiological agent of onychomycosis, does not respond well to treatment based on fluconazol.
Evolución y expresión territorial de la industria petroquímica en México
Norma Martínez Laguna
Investigaciones geográficas , 2001,
Abstract: La evolución de la industria petroquímica en nuestro país esta marcada por coyunturas históricas. Desde su genesis se caracterizo por una dependencia tecnológica y econbmica con respecto al exterior. El carácter estrategico de sus procesos en el ámbito internacional ha llevado a las grandes compa ias a participar en el sector de acuerdo con sus planes, a su vez, fue pieza clave en las politicas industriales y estrategias de desarrollo regional que el Estado impulsó, desde el decenio de los a os sesenta hasta el inicio de los ochenta, con el propósito de fortalecer la planta productiva del país y reorientar su localización hacia zonas de mayor potencial. Los espacios, cuyas ventajas competitivas permitieron su incorporación al proceso petroquímico, establecieron una vinculación económica en virtud de su especialización productiva. No obstante, la crisis financiera que ha padecido el pais, las fluctuaciones de los precios del petróleo y la desregulación comercial del sector desde los ochenta, facilitataron la existencia de un nuevo marco normativo favorable a la inversión extranjera, lo que anulo la posibilidad de aprovechar las bondades de este sector prioritario y lucrativo en la artrculacion productiva-territorial.
Organización industrial y riesgos potenciales en el municipio de Nanchital, Veracruz, México
Norma Martínez Laguna
Investigaciones geográficas , 1998,
Abstract:
Validación del sistema UMELISA HBsAg PLUS utilizando muestras de suero de cordón umbilical Validation of UMELISA HBsAg PLUS system based on umbilical cord serum samples
Kenia Romero Martínez,María T Pérez Guevara,Norma García Agramonte,Esperanza Sánchez Diéguez
Revista Cubana de Medicina Tropical , 2013,
Abstract: Introducción: la selección y el desarrollo de métodos analíticos siempre ha sido un tema importante para los laboratorios de ensayo. Para adoptar un método se hace necesario validarlo, porque el objetivo de la validación es probar la aptitud de los métodos, así como la competencia del laboratorio para realizar determinado ensayo. El sistema UMELISA HBsAg PLUS no contempla dentro de su aplicación el empleo de muestras de suero obtenidas a partir de sangre del cordón umbilical, sin embargo, con este tipo de muestra se certifica el uso de la placenta como materia prima. Objetivo: teniendo en cuenta la necesidad de demostrar que el cambio no afecta los parámetros de desempe o del sistema, se hizo su validación para muestras de suero de cordón umbilical. Métodos: se emplearon tres paneles de muestras en los estudios de especificidad, concordancia con el sistema de referencia Hepanostika HBsAg Uni-Form II, robustez, precisión a dos niveles de repetibilidad (intraensayos) y precisión intermedia (interensayos), y límite de detección. Resultados: la validación del sistema mostró los siguientes indicadores: especificidad y concordancia del 100 %, sistema robusto frente a los cambios de temperatura entre 35 y 38 °C, elevada precisión intraensayos (4,65 %) e interensayos (CV menores que 20 %), límite de detección correspondiente a una dilución de 1/10 000. Conclusiones: los resultados demostraron que el sistema UMELISA HBsAg PLUS se puede emplear para la detección de HBsAg en muestras de suero de cordón umbilical. Introduction: the selection and the development of analytical methods have always been an important issue for testing laboratories. The adoption of a method requires validation because the objective is to prove the capability of a method as well as the competencies of the laboratory to make an specific assay. The range of applications of UMELISA HbsAg PLUS system does not include the use of serum samples taken from the umbilical cord blood; however the use of placenta as raw material is certified with this kind of sample. Objective: to validate this system for umbilical cord serum sample taking into account the need of proving that this change does not affect the performance parameters of the system. Methods: three panels of samples were used to study specificity, agreement with the reference system Hepanostika HbsAg Uni-Form II, robustness, precision at two levels of repeatibility (intrassay) and intermediate precision (interassay) and detection limit. Results: validation of the system showed the following indicators: specificity and agreement of 100 %,
Comportamiento de las precipitacionesen la zona cítrica de ceballos, cuba
Medina Martínez,Norma F;
Interciencia , 2002,
Abstract: a statistical analysis of rain in the area of ceballos, ciego del ávila province, cuba, was carried out using a historical record that allows obtention of monthly rain frequency distributions for the last 82 years. an irrigation programming project is proposed with a 75% probability to exceed monthly rain. this would be more reliable than choosing a year with similar probability, as monthly rain behavior and distribution are rather irregular, even for the same month in successive years. the usable rain coefficients were determined for "valencia" orange trees in the area
Circulating Natural IgM Antibodies Against Angiogenin in the Peripheral Blood Sera of Patients with Osteosarcoma as Candidate Biomarkers and Reporters of Tumorigenesis
Yulia A. Savitskaya, Genaro Rico, Luis Linares, Roberto González, René Téllez, Eréndira Estrada, Norma Marín, Elisa Martínez, Alfonso Alfaro and Clemente Ibarra
Biomarkers in Cancer , 2012, DOI: 10.4137/BIC.S6040
Abstract: Background: Tumor immunology research has led to the identification of a number of tumor-associated self antigens, suggesting that most tumors trigger an immunogenic response, as is the case in osteosarcoma, where the detection of natural serum IgM antibodies might achieve the diagnosis of osteosarcoma. Natural IgM antibodies to tumor-associated proteins may expand the number of available tumor biomarkers for osteosarcoma and may be used together in a serum profile to enhance test sensitivity and specificity. Natural IgM antibodies can be consistently detected in the peripheral blood sera months to years before the tumor is diagnosed clinically. The study of the level of a potential biomarker many months (or years) prior to diagnosis is fundamentally important. Integrated circulating and imaging markers in clinical practice treating osteosarcoma have potential applications for controlling tumor angiogenesis. Objectives: To study the expression of natural IgM antibodies to the tumor antigens of angiogenesis in the peripheral blood sera of osteosarcoma patients and healthy individuals, and to develop serum-based predictive biomarkers. Methods: Peripheral venous blood samples were collected from 117 osteosarcoma patients and 117 patients with other tumors. All diagnosis was histologically confirmed. Staging of patients was performed according to the Enneking Surgical Staging System. The control group consisted of 117 age- and sex- matched healthy individuals. In this study, novel immunoconjugates were designed, synthesized and then used to develop a rapid, specific and sensitive enzyme-linked immunosorbent assay (ELISA) method to detect angiogenin (ANG)–IgM directly in the peripheral blood sera of humans. Results: Serum ANG–IgM levels are significantly higher in osteosarcoma patients than in healthy individuals (P < 0.005). Serum ANG–IgM levels varied widely, but were highly dependent on the concentration of IgM (r = 0.85; P < 0.0005). We found ANG–IgM in the sera of 85% of newly diagnosed osteosarcoma patients and ANG–IgM levels were significantly higher in osteosarcoma patients compared to any other tumors (P < 0.001). Conclusions: These results demonstrated that the combined biomarker ANG–IgM has greater sensitivity and specificity in early diagnosis of osteosarcoma patients than the traditional biomarkers (ANG and vascular endothelial growth factor). Circulating ANG–IgM immune complexes can potentially serve as a biomarker for increased risk of osteosarcoma, because relatively high serum levels were also detected in otherwise healthy individuals with a first degree family history of osteosarcoma and in patients with a diagnosis of benign conditions. Immunological aspects of angiogenesis for managing osteosarcoma will have a practical value in early diagnosis, prognosis and monitoring response to antiangiogenic therapy.
Comparison and overlap of sympatric wild ungulate diet in Cazorla, segura and las Villas Natural Park
Martínez Martínez, T.
Pirineos : Revista de Ecología de Monta?a , 2002,
Abstract: This paper analyses the trophic relationships and the degree of overlap between the diet of Spanish ibex (Capra pyrenaica), red deer (Cervus elaphus), fallow deer (Dama dama) and mouflon (Ovis musimon) in the Cazorla, Segura and Las Villas National Park (Southeastern of Spain). Stomach content was used as the basis for diet evaluation. The most heavily consumed plant species by the four herbivores were Quercus rotundifolia, Phillyrea latifolia, Rosmarinus officinalis, Oryzopsis paradoxa and Festuca arundinacea. Spanish ibex and red deer were the ungulates with the most similar diet (53.7% overlap), both were browsers and consumed large amounts of woody matter. Fallow deer and mouflon had similar feeding habits, both are grazers and have a high intake of grasses. There were very low levels of overlap between the ibex and red deer diet with that of fallow deer and mouflon, respectively. Mouflon was the largest forbs consumer, fallow deer consumed most camephytes and red deer consumed most trees and shrubs. None of the four ungulates had absolutely definitive diets that could class them strictly as browsers or grazers, however certain trends suggested that ibex and red deer primarily behave as browsers while fallow deer and mouflon are grazers, although this was not a strict division. [fr] Nous avons étudié le degré de superposition entre la diète du bouquetin (Capra pyrenaica, cerf (Cervus elaphus), daim (Dama dama) et mouflon (Ovis musimon) dans le Parc National de Cazorla, Segura et Las Villas (SE de l'Espagne). Pour l'évaluation de la diète, nous nous sommes basés sur les contenus stomachaux. Les espèces les plus consommées par les quatre herbivores étaient Quercus rotundifolia, Phillyrea latifolia, Rosmarinus officinalis, Oryzopsis paradoxa et Festuca arundinacea. Le bouquetin et le cerf montraient la diète la plus semblable (53,77o de superposition) puisque tous deux broutaient une grande quantité de matière ligneuse. Le mouflon et le daim montraient des habitudes similaires au niveau de l'alimentation, mangeant des herbes et consommant une grande quantité de graminées. Les diètes du bouquetin et du cerf ne se superposaient que très peu avec celles, respectivement, du daim et mouflon. Le mouflon consommait beaucoup de mégaphorbes tandis que le daim consommait surtout des chamaephytes et le cerf principalement arbres et arbrisseaux. Aucun des quatre ongulés étudiés montrait des diètes très strictes (broutage ou consommateur de graminées); cependant, on peut signaler que le bouquetin et le cerf présentaient plus des caractères de brouteurs tandis que le
Religión, política y capital simbólico: reflexiones en torno al caso de Santiago del Estero. (Argentina, 1990-2005)
Martínez,Ana T.;
Revista argentina de sociolog?-a , 2009,
Abstract: alter a brief narration of political and religious processes happened in santiago del estero, from 1980 decade, until the beginnings of 2006, the text opens a theoretical reflection upon multiformity and importance of the symbolic capital in local society, just in its symbolic capital determinations, as in what we could name religious capital. in this way, it suggests the utility of studying carefully the social construction processes of beliefs and the meanings of the indetermination in what bourdieu calls symbolic capital, in order to understand political domination in the province, and analyse the 90′s events that confronted two agents in this society of santiago: the one that spoke about politics from the religious side, and the one that had built a religious power from the political side.
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