oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 386 )

2018 ( 496 )

2017 ( 537 )

2016 ( 835 )

Custom range...

Search Results: 1 - 10 of 374195 matches for " Noel Padrón Pérez "
All listed articles are free for downloading (OA Articles)
Page 1 /374195
Display every page Item
Helicobacter pylori y enfermedad péptica ulcerosa
Padrón Pérez,Noel; Fernández Vallín-Cárdenas,Eulalia;
Revista Cubana de Medicina General Integral , 1998,
Abstract: a review on the connection of helicobacter pylori with peptic ulcer disease was made for the family physicians. epidemiological data and diagnostic methods were included. the role of helicobacter pylori in the genesis of ulcer relapses and the significant reduction of recurrences after the erradication with antimicrobial therapy are approached in the present paper. immunization as an instrument of prevention and treatment would be an important achievement that is mentioned as a future alternative to fight ulcer associated with the infection
Ebrotidina: nuevo antagonista H2
Padrón Pérez,Noel; Fernández Vallín-Cárdenas,Eulalia;
Revista Cubana de Medicina General Integral , 1999,
Abstract: a bibliographic review on the new h2 antagonist, ebrotidine, that presents advantages in comparison with other antisecretory drugs, is made. the gastroprotective properties and the anti h. pylori activity of the drug in the treatment of peptic ulcer are mentioned in this paper.
Helicobacter pylori y enfermedad péptica ulcerosa
Noel Padrón Pérez,Eulalia Fernández Vallín-Cárdenas
Revista Cubana de Medicina General Integral , 1998,
Abstract: Se realizó una revisión dirigida a los médicos de la familia sobre la relación del Helicobacter pylori y la enfermedad péptica ulcerosa. Se incluyen datos epidemiológicos y métodos diagnósticos de la infección. El papel de Helicobacter pylori en la génesis de las recidivas ulcerosas y la significativa disminución de las recurrencias posterior a la erradicación con la terapia antimicrobiana, son aspectos abordados en el presente trabajo. La inmunización como arma de prevención y tratamiento sería un importante logro que se menciona como una futura alternativa para combatir la úlcera asociada a la infección A review on the connection of Helicobacter pylori with peptic ulcer disease was made for the family physicians. Epidemiological data and diagnostic methods were included. The role of Helicobacter pylori in the genesis of ulcer relapses and the significant reduction of recurrences after the erradication with antimicrobial therapy are approached in the present paper. Immunization as an instrument of prevention and treatment would be an important achievement that is mentioned as a future alternative to fight ulcer associated with the infection
Ebrotidina: nuevo antagonista H2
Noel Padrón Pérez,Eulalia Fernández Vallín-Cárdenas
Revista Cubana de Medicina General Integral , 1999,
Abstract: Se realizó una revisión bibliográfica sobre un nuevo antagonista H2, la ebrotidina, que exhibe ventajas con respecto a otros medicamentos antisecretores. Las propiedades gastroprotectoras y la actividad anti H. pylori del fármaco, en el tratamiento de la enfermedad péptica ulcerosa, se mencionan en el presente trabajo. A bibliographic review on the new H2 antagonist, ebrotidine, that presents advantages in comparison with other antisecretory drugs, is made. The gastroprotective properties and the anti H. pylori activity of the drug in the treatment of peptic ulcer are mentioned in this paper.
Presenilinas, Apo E y enfermedad de Alzheimer
Padrón Pérez,Noel; Gra Menéndez,Silvia; Llibre Rodríguez,Juan de Jesús;
Revista Cubana de Investigaciones Biom??dicas , 2002,
Abstract: a review was made on the identification and isolation of the genes codyfing for presenilin 1 and 2 (chromosome 14 and 21, respectively), as well as on the detection of mutations, which is one of the achievements of the genetic strategy to study alzheimer?s disease. these investigations have contributed to explain a percentage of the cases with family history and early-onset affection. the apo e gene, mainly the presence of allele e4 located in chromosome 19, is associated with late-onset family alzheimer?s disease. some aspects showing the remarkable advance attained in the knowledge of the physiopathogenic events, which are subjacent to the most frequent cause of dementia and are not clear yet, are dealt with.
Péptido beta amiloide, proteína Tau y enfermedad de Alzheimer
Gra Menéndez,Silvia; Padrón Pérez,Noel; Llibre Rodríguez,Juan de Jesús;
Revista Cubana de Investigaciones Biom??dicas , 2002,
Abstract: alzheimer?s disease, the most common cause of dementia, is updated in this paper. aspects related to chromosomes 21 and 17 are established. the mutations in the gene of amyloid precursor protein, located in chromosome 21, are the responsible for 5 to 20 % of the cases of early-onset family alzheimer?s disease. the amyloid precursor protein on beign processed by an amyloidogenic route originates the amyloid-beta peptide, which deposits itself on the senile plaques and causes direct toxic effects on neurons. the gene codifying the tau protein synthesis is located on chromosome 17. the mutations in this gene caused an irreversible phosphorylation of the protein that impedes its normal function and makes easy its autoaggregation, forming this way the neurofibrillar tangles. although it is still under study, it is accepted that the amyloid-beta deposit is one of the first causes of the disease; however, the unique correlation established between the intensity of the disease and the pathological injuries is observed in the neurofibrillar tangles.
Péptido beta amiloide, proteína Tau y enfermedad de Alzheimer
Silvia Gra Menéndez,Noel Padrón Pérez,Juan de Jesús Llibre Rodríguez
Revista Cubana de Investigaciones Biom??dicas , 2002,
Abstract: Se realizó una actualización sobre la enfermedad de Alzheimer, que constituye la causa más frecuente de demencia. Se establecieron aspectos relacionados con los cromosomas 21 y 17. Mutaciones en el gen de la proteína precursora amiloidea, localizado en el cromosoma 21, son responsables de 5 a 20 % de los casos de enfermedad de Alzheimer familiar precoz. La proteína precursora amiloidea al ser procesada por una vía amiloidogénica origina el beta amiloide, el cual se deposita en las placas seniles y causa efectos tóxicos directos sobre las neuronas. En el cromosoma 17 se encuentra el gen que codifica la síntesis de la proteína Tau. Mutaciones en este gen provocan una fosforilación irreversible de la proteína que impiden su función normal y facilitan su autoagregación, formando los ovillos neurofibrilares. Aunque aún en estudio, se acepta que el depósito de beta amiloide constituye una de las primeras causas de la enfermedad, sin embargo, la única correlación establecida entre la intensidad de la enfermedad y las lesiones patológicas se da con los ovillos neurofibrilares. Alzheimer’s disease, the most common cause of dementia, is updated in this paper. Aspects related to chromosomes 21 and 17 are established. The mutations in the gene of amyloid precursor protein, located in chromosome 21, are the responsible for 5 to 20 % of the cases of early-onset family Alzheimer’s disease. The amyloid precursor protein on beign processed by an amyloidogenic route originates the amyloid-beta peptide, which deposits itself on the senile plaques and causes direct toxic effects on neurons. The gene codifying the Tau protein synthesis is located on chromosome 17. The mutations in this gene caused an irreversible phosphorylation of the protein that impedes its normal function and makes easy its autoaggregation, forming this way the neurofibrillar tangles. Although it is still under study, it is accepted that the amyloid-beta deposit is one of the first causes of the disease; however, the unique correlation established between the intensity of the disease and the pathological injuries is observed in the neurofibrillar tangles.
Presenilinas, Apo E y enfermedad de Alzheimer
Noel Padrón Pérez,Silvia Gra Menéndez,Juan de Jesús Llibre Rodríguez
Revista Cubana de Investigaciones Biom??dicas , 2002,
Abstract: Se hizo una revisión sobre la identificación y el aislamiento de los genes que codifican para la presenilina 1 y 2 (cromosoma 14 y 21 respectivamente), así como la detección de mutaciones, lo que constituye uno de los logros de la estrategia genética para el estudio de la enfermedad de Alzheimer. Estas investigaciones han contribuido a explicar un porcentaje de los casos con antecedentes familiares e inicio precoz de la afección. El gen de la Apo E, fundamentalmente la presencia del alelo e4 localizado en el cromosoma 19 se asocia con la enfermedad de Alzheimer familiar de inicio tardío. Se trataron aspectos que evidencian el notable avance alcanzado en el conocimiento de los eventos fisiopatogénicos, aún sin esclarecer del todo, que subyacen en la causa más frecuente de demencia. A review was made on the identification and isolation of the genes codyfing for presenilin 1 and 2 (chromosome 14 and 21, respectively), as well as on the detection of mutations, which is one of the achievements of the genetic strategy to study Alzheimer’s disease. These investigations have contributed to explain a percentage of the cases with family history and early-onset affection. The Apo E gene, mainly the presence of allele e4 located in chromosome 19, is associated with late-onset family Alzheimer’s disease. Some aspects showing the remarkable advance attained in the knowledge of the physiopathogenic events, which are subjacent to the most frequent cause of dementia and are not clear yet, are dealt with.
Tratamiento de la infección por Helicobacter pylori: Comentario al respecto
Padrón Pérez,Noel; Fernández Vallín-Cárdenas,Eulalia; Qui?ones Pérez,Dianelys;
Revista Cubana de Investigaciones Biom??dicas , 1999,
Abstract: a bibliographic review on the schedules of treatment recommended in the infection caused by helicobacter pylori was made. the high rates of erradication attained by the triple and quadruple therapies allow their use as first and second line treatment, respectively. those affections associated with the infection, in which the erradicating treatment should be applied, are related. the utilization of antimicrobials in areas where the resistance was high reduced the efficacy of the therapy used. the anti-h. pylori vaccine became a new option of treatment. the use of different mucous sites of vaccination with adjuvants of low toxicity was also dealt with in this paper. the therapeutic effectiveness of the vaccine according to the authors proved to be high in experimental models and achieved 100 % of protection against the infection caused by this gramnegative bacterium.
Tratamiento de la infección por Helicobacter pylori: Comentario al respecto
Noel Padrón Pérez,Eulalia Fernández Vallín-Cárdenas,Dianelys Qui?ones Pérez
Revista Cubana de Investigaciones Biom??dicas , 1999,
Abstract: Se realizó una revisión bibliográfica sobre las pautas de tratamiento recomendadas en la infección causada por Helicobacter pylori. Las altas tasas de erradicación logradas por los esquemas triple y cuádruple, hacen que éstos sean utilizados como primera y segunda línea de tratamiento respectivamente. Se relacionan las afecciones asociadas con la infección, en las que se debe utilizar el tratamiento erradicador. El uso de antimicrobianos, en zonas donde la resistencia era elevada, redujo la eficacia del esquema utilizado. La vacuna anti-H. pylori constituyó una novedosa opción de tratamiento. La utilización de diferentes sitios mucosos de vacunación con adyuvantes de baja toxicidad, también se trataron en este trabajo. La efectividad terapéutica de la vacuna, según los autores, resultó alta en modelos experimentales y alcanzó 100 % de protección frente a la infección por esta bacteria gramnegativa. A bibliographic review on the schedules of treatment recommended in the infection caused by Helicobacter pylori was made. The high rates of erradication attained by the triple and quadruple therapies allow their use as first and second line treatment, respectively. Those affections associated with the infection, in which the erradicating treatment should be applied, are related. The utilization of antimicrobials in areas where the resistance was high reduced the efficacy of the therapy used. The anti-H. pylori vaccine became a new option of treatment. The use of different mucous sites of vaccination with adjuvants of low toxicity was also dealt with in this paper. The therapeutic effectiveness of the vaccine according to the authors proved to be high in experimental models and achieved 100 % of protection against the infection caused by this gramnegative bacterium.
Page 1 /374195
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.