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Search Results: 1 - 10 of 297759 matches for " Nita J. Matzen "
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A Virtual World for Collaboration: The AETZone
Amelia W. Cheney,Robert L. Sanders,Nita J. Matzen,Stephen C. Bronack
Themes in Science and Technology Education , 2009,
Abstract: Participation in learning communities, and the construction of knowledge in communities ofpractice, are important considerations in the use of 3D immersive worlds. This article describesthe creation of this type of learning environment in AETZone, an immersive virtualenvironment in use within graduate programs at Appalachian State University since 2000.Both student and faculty perceptions of elements such as presence, co-presence, and the forgingof active community are presented, along with examples of formal and informal activitieswhich serve as the base for teaching and learning in the Zone.
Liquor Habit Transmission Model  [PDF]
Nita H. Shah, Bijal M. Yeolekar, Nehal J. Shukla
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.68112
Abstract: In this paper, we analyse population dynamics of liquor habit. Liquor free and Liquor endemic equilibrium are computed. The local and global stabilities of the proposed problem are established. The numerical simulation is given to validate the transmission of population indifferent compartment using state-space model.
Improving HTc Josephson Junctions (HTc JJ) by annealing: the role of vacancy-interstitial annihilation
M. Sirena,S. Matzen,N. Bergeal,J. Lesueur,G. Faini,R. Bernard,J. Briatico
Physics , 2007, DOI: 10.1063/1.2783227
Abstract: We have studied the annealing effect in transport properties of High temperature Josephson Junctions (HTc JJ) made by ion irradiation. Low temperature annealing (80 degrees Celsius) increases the JJ transition temperature (TJ) and the Ic.Rn product, where Ic is the critical current and Rn the normal resistance. We found that the spread in JJ characteristics can be lowered by sufficient long annealing times. Using random walk numerical simulations, we showed that the characteristic annealing time and the evolution of the spread in JJ characteristics can be explained by a vacancy-interstitial annihilation process rather than by an oxygen diffusion one.
An inventory model for deteriorating items with exponentially increasing demand and shortages under inflation and time discounting
Mehta,Niketa J.; Shah,Nita H.;
Investiga??o Operacional , 2003,
Abstract: a lot-size inventory model for deteriorating items is derived with exponentially increasing demand by allowing complete backlogging. the effects of inflation and time value of money are studied on the model. it is assumed that the units in inventory deteriorate over time at a constant rate. the inventory policy is discussed over a finite planning horizon with several reorder points. sensitivity analysis of the optimal solution with respect to the parameters of the system is carried out with the help of a numerical example.
Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics
Jason A Wilken, Kristy T Webster, Nita J Maihle
Journal of Ovarian Research , 2010, DOI: 10.1186/1757-2215-3-7
Abstract: An in vitro model of primary trastuzumab-resistant ovarian cancer was created by long-term culture of HER2-positive ovarian carcinoma-derived cell lines with trastuzumab. Trastuzumab treated vs. untreated parental cells were compared for HER receptor expression, trastuzumab sensitivity, and sensitivity to other HER-targeted therapeutics.In contrast to widely held assumptions, here we show that ovarian cancer cells that are not growth inhibited by trastuzumab are still responsive to trastuzumab. Specifically, we show that responsiveness to alternative HER-targeted inhibitors, such as gefitinib and cetuximab, is dramatically potentiated by long-term trastuzumab treatment of ovarian cancer cells. HER2-positive ovarian carcinoma-derived cells are, therefore, not "unresponsive" to trastuzumab as previously assumed, even when they not growth inhibited by this drug.Given the recent success of EGFR-targeted therapeutics for the treatment of other solid tumors, and the well-established safety profile of trastuzumab, results presented here provide a rationale for re-evaluation of trastuzumab as an experimental ovarian cancer therapeutic, either in concert with, or perhaps as a "primer" for EGFR-targeted therapeutics.Cancer diagnostics and treatment are being revolutionized by the clinical application of information generated during the past three decades of basic cancer research. Some of the most difficult to treat malignancies have been shown to have predictable alterations in key signal transduction pathways, and the discovery of these abnormalities has allowed the development of improved, side-effect sparing biologically-targeted therapeutics. Examples of these novel drugs include imatinib (Gleevec), trastuzumab (Herceptin), gefitinib (Iressa) and erlotinib (Tarceva), cetuximab (Erbitux) and panitumumab (Vectibix), and sunitinib (Sutent), which have been FDA approved for the treatment of chronic myelogenous leukemia, HER2-positive breast cancer, non-small cell lung cancer,
SEIR Model and Simulation for Vector Borne Diseases  [PDF]
Nita H. Shah, Jyoti Gupta
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.48A003
Abstract:

An epidemic model is a simplified means of describing the transmission of infectious diseases through individuals. The modeling of infectious diseases is a tool which has been used to study the mechanisms by which diseases spread, to predict the future course of an outbreak and to evaluate strategies to control an epidemic. Epidemic models are of many types. Here, SEIR model is discussed. We first discuss the basics of SEIR model. Then it is applied for vector borne diseases. Steady state conditions are derived. A threshold parameter R0 is defined and is shown that the disease will spread only if its value exceeds 1. We have applied the basic model to one specific diseases-malaria and did the sensitivity analysis too using the data for India. We found sensitivity analysis very important as it told us the most sensitive parameter to be taken care of. This makes the work more of practical use. Numerical simulation is done for vector and host which shows the population dynamics in different compartments.

The effectiveness of face to face education using catharsis education action (CEA) method in improving the adherence of private general practitioners to national guideline on management of tuberculosis in Bandung, Indonesia
Nita Arisanti
Asia Pacific Family Medicine , 2012, DOI: 10.1186/1447-056x-11-2
Abstract: The objective of the study was to determine the effectiveness of CEA method in improving the private general practitioners' (PPs) adherence to the national guideline on the management of tuberculosis patients in Bandung District, Indonesia.A randomized controlled trial was done. For the intervention group, a session of the CEA method was delivered to PPs while brief reminder with provision of pamphlet was used for the comparative group.A total of 82 PPs were included in the analysis. The intervention group showed some positive trends in adherence especially in the use of sputum as first laboratory examination (RR = 1.24) and follow up (RR = 1.37), though not reaching statistical significance. After intervention PPs in CEA group maintained the adherence, but PPs in pamphlets group showed deterioration (score before to after: -12.5).Face to face education using CEA method seems to be as effective as brief reminder with provision of pamphlet in improving the adherence. CEA offers additional information that can be useful in designing intervention programs to improve the adherence to guideline.Mycobacterium tuberculosis infects one-third of the world's population and imposes a global burden of an estimated 8 million new cases and 1.8 million deaths yearly [1]. More than 90% of global tuberculosis (TB) cases and deaths occur in the developing world, where 75% of cases are in the most economically productive age group (15-54 years). An adult with TB loses on average three to four months of work time [1,2].Indonesia with a population of over 220 millions carries the heavy burden of TB. Indonesia still ranks third among the 22 high-burden countries [2]. In Bandung, one of the cities in West Java Province, Indonesia, case detection rate (CDR) did not reach the Indonesia target of 70% [3]. The Government of Indonesia considers TB control to be a high priority within the health-care system [3-5]. A strategy for incremental involvement of the private practitioners in DOTS (Dire
Determining the Neutral D Mixing Parameters
Sinha, Nita
High Energy Physics - Phenomenology , 2008,
Abstract: Evidence for mixing in the neutral D meson system has recently been reported. Assuming negligible CP violation, non-vanishing width and mass differences between the two neutral D mass eigenstates has been found. Theoretical predictions of these are rather difficult, obscuring detection of New Physics contributions. However, the observation of CP violation in the D system would be a good signal of New Physics. We briefly describe the formalism that describes the neutral D decay and mixing, and present a method to determine all the mixing parameters accurately allowing for arbitrary CP violation.
Comparison Of 137Cs Vertical Distribution Profile At Soil Layer Obtained By Measurement And Simulation
Nita Suhartini
Makara Seri Sains , 2006,
Abstract: This investigation aimed to compare a profile of 137Cs vertical distribution at soil layer in the stable site (undisturbed site). Conservation forest that has been becoming as conservation area since 1925 namely Gn. Pangrango was selected as study site. Sampling of soil was done in Pancawati - Ciawi. Sampling was done by using scrapper ( 20 x 50) cm, with layer increment of 2 cm until the depth of 24 cm (107 kg/m2) or 26 cm (137 kg/m2), and sampling was done at 5 points. Soil samples were brought to the laboratory for preparation and analysis of 137Cs content by using MCA at 662 keV energy. The result showed that the comparison of 137Cs vertical distribution profile between measurement and simulation has a significant differences.
Family and Culture as Endemic Deterants Tilting the Gender Equilibrium - The Case of Ajay Mohan Jain's Novel
Nita Jain
Venets : The Belogradchik Journal for Local History, Cultural Heritage and Folk Studies , 2011,
Abstract: Identity politics and a politics of culture have largely preempted South Asian literary studies since the days of post-colonial theory. While proactive attitudes to development have substantiated the conventional modes of thinking responsible for shaping the contemporary Indian society, the history of the subcontinent has been contoured by visions of nativism in turn formed by the cultural ethos of the land. As the new nation matured, the earliest national leaders along with Mahatma Gandhi worked hard at creating an environment of cosmopolitan liberalism. Today, with intrepid globalization, the South Asian community and more closely, the Indian psyche has acquired an interface of healthy multiculturalism, which in its turn has evolved out of an assertive attitude of political correctness. All this has grown over a period of time and the Indian society has assumed identities compatible with its consciousness; as that of nationalism, multiculturalism, cosmopolitan liberalism and religious secularism. Spatial boundaries within the nation often determined the typical nature of the identity. My attempt will be to study Ajay Mohan Jain’s, “Nothing can be as crazy…’ in the light of the above hypothesis.
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