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Search Results: 1 - 10 of 483 matches for " Nima Etminan "
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The Impact of Experimental Preconditioning Using Vascular Endothelial Growth Factor in Stroke and Subarachnoid Hemorrhage
Sven Oliver Eicker,Moritz Hoppe,Nima Etminan,Stephan Macht
Stroke Research and Treatment , 2013, DOI: 10.1155/2013/948783
Abstract:
The Impact of Experimental Preconditioning Using Vascular Endothelial Growth Factor in Stroke and Subarachnoid Hemorrhage
Sven Oliver Eicker,Moritz Hoppe,Nima Etminan,Stephan Macht,Jason Perrin,Hans-Jakob Steiger,Daniel H?nggi
Stroke Research and Treatment , 2013, DOI: 10.1155/2013/948783
Abstract: Vascular endothelial growth factor (VEGF) stimulating angiogenesis was shown to be a potential novel therapeutic approach for the treatment of ischemic vascular diseases. The goal of the present study was to examine whether transfection of VEGF before occurrence of major stroke (part I) and cerebral vasospasm after experimental subarachnoid hemorrhage (SAH; part II) develops neuroprotective qualities. A total of 25 (part I) and 26 (part II) brains were analyzed, respectively. In part one, a significant reduction of infarct volume in the VEGF-treated stroke animals (43% reduction, ) could be detected. In part two, significant vasospasm was induced in all hemorrhage groups . Analyzing microperfusion, a significant higher amount of perfused vessels could be detected , whereas no significant effect could be detected towards macroperfusion. Histologically, no infarctions were observed in the VEGF-treated SAH group and the sham-operated group. Minor infarction in terms of vasospasm-induced small lesions could be detected in the control vector transduced group and saline-treated group . The present study demonstrates the preconditioning impact of systemic intramuscular VEGF injection in animals after major stroke and induced severe vasospasm after SAH. 1. Introduction Cerebral vasospasm and delayed cerebral ischemia contribute the major part of secondary morbidity and mortality after severe subarachnoid hemorrhage (SAH) [1–5]. Despite the current treatment strategies, the rate of related permanent disability is estimated at 10% to 20% [6–9]. Vascular endothelial growth factor (VEGF) is involved in neurogenesis, inhibition of apoptosis, learning, and memory [10]. It can directly promote neuroprotection, but first of all VEGF is the main factor responsible for angiogenesis whereby an indirect neuroprotection is discussed. VEGF expression is increased during cerebral ischemia in humans and animals [11]. However, endogenous VEGF seems to be insufficient to protect the brain from ischemic injury completely. Interestingly, it could be shown that exogenous administrated VEGF induces angiogenic changes that result in a reduction of cerebral ischemic injury [12, 13]. For this reason VEGF was adopted as a potential novel therapeutic approach for the treatment of ischemic vascular disease, particularly in ischemic stroke [14–18]. The aim of the present experimental study was to examine the effect of systemic overexpression of VEGF prior to stroke and SAH with regard to cerebral infarction, vasospasm, and perfusion. 2. Material and Methods This study was carried out in
Measures and Safeguards to Realize Stable Poverty Alleviation in Contiguous Destitute Areas Based on Human Capital Development — A Case Study of Xialatuo Village  [PDF]
Garong Nima
Open Journal of Social Sciences (JSS) , 2019, DOI: 10.4236/jss.2019.74007
Abstract: Based on the perspective of human capital development, this paper explores the current situation and development of poverty alleviation in the three aspects of education, training, information resources and management organization according to the author’s research in Xialatuo Village, Luhuo County, Ganzi Tibetan Autonomous Prefecture. The precipitation and rapid development of education is the fundamental factor for the stable and stable development of the village; The advantage of information resources reduces the gap between urban and rural areas and promotes the economic development of the village; The measures and implementation of organization and management guide the development of various aspects in the village and create a lot of development conditions for farmers. Finally, the author gives some suggestions on how to stabilize poverty alleviation.
Prevalence of trichomoniasis in women referring to health centers in Yazd
Samad Etminan,Mahshid Bokaee
Knowledge & Health Journal , 2007,
Abstract: Introduction: Trichomonas virginals is a parasitic protozoan that is the cause of trichomoniasis, a sexually transmitted disease (STD) of worldwide importance. The disease encompasses a broad range of symptoms ranging from a state of severe inflammations and irritation with a frothy malodorous discharge and itching. Recent data have shown that the annual incidence of trichomoniasis is more than 170 million cases worldwide. The aim of this survey was to determine the association between demographic factors and the clinical manifestation of disease. Methods: For this cross sectional study 384 women referred to health centers were randomly selected. Initial data were gathered through a face to face interview and were completed by their results of the two methods of laboratory tests that had performed separately on each sample. Data were all collected and analyzed using suitable tests asχ2 test. Results: The overall prevalence of trichomoniasis was 2.1% (of 384) by direct microscopy and 2.6% (of 384) by culture detection. There was no significant statistical difference between trichomoniasis and job (P>0.05). There was a significant statistical difference between trichomoniasis and delivery numbers (P=0.003). Conclusion: Results of the study showed that the prevalence of this disease was lower than the many other studies but higher than other studies. The different sensitivity and specify might be depended on their methods of laboratory tests besides demographic and cultural factors.
Local Delivery of Nimodipine by Prolonged-Release Microparticles—Feasibility, Effectiveness and Dose-Finding in Experimental Subarachnoid Hemorrhage
Daniel H?nggi, Jason Perrin, Sven Eicker, Kerim Beseoglu, Nima Etminan, Marcel Alexander Kamp, Hi-Jae Heiroth, Nadia Bege, Stephan Macht, Katrin Frauenknecht, Clemens Sommer, Thomas Kissel, Hans-Jakob Steiger
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0042597
Abstract: Background and Purpose To investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH). Methods 70 male Wistar rats were categorized into three groups: 1) sham operated animals (control), 2) animals with SAH only (control) and the 3) treatment group. SAH was induced using the double hemorrhage model. The treatment group received different concentrations (20%, 30% or 40%) of nimodipine microparticles. Angiographic vasospasm was assessed 5 days later using digital subtraction angiography (DSA). Histological analysis of frozen sections was performed using H&E-staining as well as Iba1 and MAP2 immunohistochemistry. Results DSA images were sufficient for assessment in 42 animals. Severe angiographic vasospasm was present in group 2 (SAH only), as compared to the sham operated group (p<0.001). Only animals within group 3 and the highest nimodipine microparticles concentration (40%) as well as group 1 (sham) demonstrated the largest intracranial artery diameters. Variation in vessel calibers, however, did not result in differences in Iba-1 or MAP2 expression, i.e. in histological findings for secondary brain injury. Conclusions Local delivery of high-dose nimodipine prolonged-release microparticles at high concentration resulted in significant reduction in angiographic vasospasm after experimental SAH and with no histological signs for matrix toxicity.
A New Approach to Complex Bandpass Sigma Delta Modulator Design for GPS/Galileo Receiver  [PDF]
Nima Ahmadpoor, Ebrahim Farshidi
Circuits and Systems (CS) , 2012, DOI: 10.4236/cs.2012.31006
Abstract: In this paper, new complex band pass filter architecture for continuous time complex band pass sigma delta modulator is presented. In continuation of paper the modulator is designed for GPS and Galileo receiver. This modulator was simulated in standard 0.18 μm CMOS TSMC technology and has bandwidth of 2MHz and 4MHz for GPS and Galileo centered in 4.092 MHz. The dynamic range (DR) is 56.5/49 dB (GPS/Galileo) at sampling rate of 125 MHz. The modulator has power consumption of 4.1 mw with 3 V supply voltage.
Ratio of dielectric strength of structural and secondary relaxation close to the glass transition for PPGE and DGEBA  [PDF]
Soheil Sharifi, Nima bahreini
Natural Science (NS) , 2012, DOI: 10.4236/ns.2012.47066
Abstract: Here, dielectric spectroscopy is used in the fre- quency range from 10-2 Hz up to 107 Hz and we found dynamics of the primary α-and intermolecular Johari–Goldstein β-processes are strongly correlated in diglycidyl-ether of bis-phenol-A and poly phenyl glycidyl-ether (PPGE) over a wide temperature from 193 to 345 K and pressure P range from 0.1 to 600 MPa. In contrast with the widespread opinion of statistical independence of these processes the α-β mutual dependence is quantitatively confirmed in [1] analysing the temperature and pressure behavior of the α-and (JG) β-processes the investigation of the ratio of dielectric strength of two processes close to Tg evidence that the importance of secondary dy namics in relaxing external electric stresses increase in glass formers at high pressures with respect to that of the structural relaxation. We suggest that the thermal agitation, acting above Tg is at the basis of the observed result.
Investigation of Spatial and Temporal Distribution of Snow Cover by Using Satellite Imagery (Case Study: Sheshpirdam Basin)  [PDF]
Ali Liaghat, Nima Tavanpour
Open Journal of Geology (OJG) , 2016, DOI: 10.4236/ojg.2016.65028
Abstract: About one third of the water needed for agriculture in the world is generated by melting snow. Snow cover, surface and ground water recharge are considered as sustainable and renewable resources. It is therefore necessary to identify and study these criteria. The aim of this study is to determine the spatial and temporal distribution of snow cover in the district of the Sheshpir basin in Fars province (in south of Iran). Ground-based observation of snow covers, especially in mountainous areas, is associated with many problems due to the insufficient accuracy of optical observation, as opposed to digital observation. Therefore, GIS and remote sensing technology can be partially effective in solving this problem. Images of Landsat 5TM and Landsat 7TM satellites were used to derive snow cover maps. The images in ENVI 4.8 software were classified by using the maximum likelihood algorithm. Other spatial analyses were performed in ARC-GIS 9.3 software. The maximum likelihood method was accuracy assessed by operation points of testing. The least and the average of overall accuracy of produced maps were found to be 91% and 98%, respectively. This demonstrates that the maximum likelihood method has high performance in the classification of images. Overall snow cover and the review of terrain through the years 2008-2009 and 2009-2010 showed that snow cover begins to accumulate in November and reaches its highest magnitude in February. Finally, no trace of snow can be observed on the surface of the basin in the month of May. By average, 34% of the basin is covered in snow from November through to May.
An Improved Model for Geostatistical Simulation of Fracture Parameters and their Effect on Static and Dynamic Models
A.H. Etminan and A. Seifi
The Open Petroleum Engineering Journal , 2008, DOI: 10.2174/1874834100801010047]
Abstract: This article presents a method for simulation of continuous and discrete fracture parameters distributions in hydrocarbon reservoirs using Sequential Indicator Simulation (SIS) and Sequential Gaussian Simulation (SGS) methods. Fracture parameters including azimuth, dip and density are integrated with the porosity and permeability values determined in the models. Based on this study we have identified stylolites, occluded fractures, vugs (isolated pores) and open fractures using core data from 13 wells in one of the southern Iranian gas fields. A model is constructed using SIS that contains fractures. This enables us to evaluate the role of fractures in the model enhancing permeability and their predictability in reservoirs. For this purpose, only the fractured blocks of the mentioned model were selected for fractures density, azimuth and dip modeling. Afterward, a novel function named Fracture Effect Factor (FEF) is introduced to calculate the effect of fractures on permeability model in the fractured blocks. For porosity modeling, fractures type model is used as an aid for increasing the accuracy of the modeling so that for the mentioned four fracture types, individual variograms are constructed and porosity estimation in each block is performed based on its related variogram. The proposed model is compared with dual porosity model on a fractured reservoir in South of Iran for a period of 18 years. The results of this research indicate that this method can visualize a more real estimation of dynamic and static behavior of the reservoir.
The Prevalence of Candida Vaginitis among Women aged 15 - 49 Years in Yazd, Iran
Etminan,S,Zarinkatsh,H,Lotfee, M.
Medical Laboratory Journal , 2008, DOI: http://www.goums.ac.ir/mljgoums/index.php?&slct_pg_id=10&sid=1&slc_lang=en
Abstract: Background and objectives: Candida vaginitis is one of the most infectiousdiseases which millions of women aged 45-15 years are annually beingreferred to clinics. The purpose of this study was to determine the prevalenceand the relationship between Candida Vaginitis and Variables such as age,Contraceptive procedures and the number of labor.Material and Methods: we carried out this descriptive-analytic study on384 Subjects Selected randomly. We used Statistical test to analyze the data.Results: The highest is related to under thirty-five year old Subjects and theLowest to under ninety. It has been reported that oral Contraceptive versusother methods is associated with the greatest frequency of Vaginitis (38.9%)and Condom with the lowest.Conclusion: we conclude that the prevalence of Candida Vaginitis in 15-49year old woman referred to YAZA health care Center is 26.6%.Key Words : Vulvovaginite,Candidiasis,Prevalence
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