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Search Results: 1 - 10 of 291 matches for " Nicoletta Tarozzi "
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Human Sperm Cryopreservation: Update on Techniques, Effect on DNA Integrity, and Implications for ART
Marlea Di Santo,Nicoletta Tarozzi,Marco Nadalini,Andrea Borini
Advances in Urology , 2012, DOI: 10.1155/2012/854837
Abstract: Cryopreservation of human spermatozoa—introduced in the 1960's—has been recognized as an efficient procedure for management of male fertility before therapy for malignant diseases, vasectomy or surgical infertility treatments, to store donor and partner spermatozoa before assisted reproduction treatments and to ensure the recovery of a small number of spermatozoa in severe male factor infertility. Despite the usefulness of it, cryopreservation may lead to deleterious changes of sperm structure and function: while the effects of cryopreservation on cells are well documented, to date there is no agreement in the literature on whether or not cryopreservation affects sperm chromatin integrity or on the use of a unique and functional protocol for the freezing-thawing procedure. Therefore, sperm cryopreservation is an important component of fertility management and much of its successful application seems to affect the reproductive outcome of assisted reproduction technologies (ART): appropriate use of cryoprotectants before and sperm selection technologies after cryopreservation seem to have the greatest impact on preventing DNA fragmentation, thus improving sperm cryosurvival rates. 1. Introduction The procedure that makes it possible to stabilize the cells at cryogenic temperatures is called cryopreservation, also known as an applied aspect of cryobiology or the study of life at low temperatures. Many advances in the cryopreservation technology have led to the development of methods that allow for low-temperature maintenance of a variety of cell types including male and female gametes, small multicellular organisms, and even more complex organisms such as embryos. Cryopreservation of human spermatozoa—introduced in the 1960’s [1]—has overcome many space and time limitations and now forms integral part of assisted reproduction technologies (ARTs). This technique becomes particularly important in cases of preservation of male fertility before radiotherapy or chemotherapy [2] which may lead to testicular failure or ejaculatory dysfunction. In fact, semen cryostorage seems to be the only proven method that may offer these couples a chance of having children in the future: cancer therapy could in fact lead to damage, resulting in subfertility or sterility due to gonad removal or permanent damage to germ cells caused by adjuvant therapy. In particular, the risk associated to therapy depends on several factors: the age of the patient at the time of treatment, the dose, site, and type of treatment [3]. Also some nonmalignant diseases, such as diabetes and
Translating and Doing Grounded Theory Methodology. Intercultural Mediation as an Analytic Resource übersetzen und Grounded Theory. Interkulturelle Vermittlung als analytisches Instrument
Massimiliano Tarozzi
Forum : Qualitative Social Research , 2013,
Abstract: Language is a non-neutral, but powerful research tool. This article focuses on two issues: 1. methodological suggestions ensuing from the translation of the founding text of grounded theory methodology (GTM) in the light of the recent literature regarding the translation studies and 2. philosophical reflections and methodological implications about the use of a different language in doing GTM. Both these issues can be useful for GTM practitioners, in particular for native English speakers, since they can uncover some implications of the use of the language in doing research that are commonly taken for granted and underestimated. The translation process has to do with the understanding and use of a social research method. In this sense, to translate, under certain regards, is doing research, a rigorous inquiry aimed at understanding a text. The similarities of these two parallel processes are closely reviewed. Moreover doing research in another language is a powerful analytic resource. Coding in another language requires continuous acts of interlinguistic translation so that it grows our own faculty to understanding. Differences are highlighted, by providing examples from research, among coding in English (an isolating language suitable for advanced coding and memoing) and in Italian (an inflectional language, more suitable for early coding and memoing). URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs130263 URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs130263 Sprache ist ein m chtiges, nicht-neutrales Forschungswerkzeug. Dieser Aufsatz hat sich zwei Ziele gesetzt: 1. methodologische Vorschl ge zu erarbeiten, die sich aus der übersetzungsarbeit an einem grundlegenden Text der Grounded-Theory-Methodologie (GTM) ergeben haben und die im Licht neuerer Literatur zum Problem des übersetzens betrachtet werden; 2. philosophische Reflexionen zur Verwendung einer Fremdsprache beim Arbeiten mit der GTM anzustellen und diesbezügliche methodologische Implikationen zu erw gen. Beide Ziele k nnen für GTM-Forschende (speziell für englischsprachige Muttersprachler/innen) von Nutzen sein, da auf diese Weise einige Auswirkungen der Verwendung von Sprache in der Forschungsarbeit sichtbar werden, die üblicherweise als Selbstverst ndlichkeit angesehen und untersch tzt werden. Die T tigkeit des übersetzens hat mit dem Verst ndnis und der Anwendung einer Sozialforschungsmethodik zu tun. In diesem Sinne ist übersetzen selbst eine Art des Forschens, n mlich insofern, als es sich in beiden F llen um ein fundamentales Bemühen um das Verst ndnis eines Textes handelt. Die hnlichk
Semiparametric efficiency in GMM models with auxiliary data
Xiaohong Chen,Han Hong,Alessandro Tarozzi
Mathematics , 2007, DOI: 10.1214/009053607000000947
Abstract: We study semiparametric efficiency bounds and efficient estimation of parameters defined through general moment restrictions with missing data. Identification relies on auxiliary data containing information about the distribution of the missing variables conditional on proxy variables that are observed in both the primary and the auxiliary database, when such distribution is common to the two data sets. The auxiliary sample can be independent of the primary sample, or can be a subset of it. For both cases, we derive bounds when the probability of missing data given the proxy variables is unknown, or known, or belongs to a correctly specified parametric family. We find that the conditional probability is not ancillary when the two samples are independent. For all cases, we discuss efficient semiparametric estimators. An estimator based on a conditional expectation projection is shown to require milder regularity conditions than one based on inverse probability weighting.
Le fonti slave dell’esperanto Le fonti slave dell’esperanto
Nicoletta Marcialis
Studi Slavistici , 2012,
Cooperative Hypertext: An Educational Example
Nicoletta SALA
The Turkish Online Journal of Distance Education , 2002,
La tutela del paesaggio: percorsi giuridici
Nicoletta Ferrucci
Aestimum , 2007,
Lucia Saetta e Cristina Vannini Parenti (a cura di), Blog & Nuvole. Un incontro tra la scrittura della rete e l’arte del fumetto.
Nicoletta Vallorani
Altre Modernità , 2009,
Abstract: Lucia Saetta e Cristina Vannini Parenti (a cura di), Blog & Nuvole. Un incontro tra la scrittura della rete e l’arte del fumetto.
Il Gesù di Stracci
Nicoletta Vallorani
Altre Modernità , 2010,
Abstract: Il Gesù di Stracci (Tomaso Subini, Pier Paolo Pasolini. La ricotta, Torino, Lindau, 2009, pp.221, ISBN 978-88-7180-814-7) di Nicoletta Vallorani
Path(o)s of Mourning. Memory, Death and the Invisible Body in Derek Jarman’s Blue
Nicoletta Vallorani
Altre Modernità , 2010,
Abstract: The essay addresses two quite complex issues. The first one is the virulence of the hostility toward gay men that the AIDS pandemic has released: this is the backdrop against which Jarman's extended elaboration and mourning for his own death is performed, after his diagnosis as body-positive in 1986. The second issue links to the open question of public mourning and its relation to AIDS in the early 90s, when the AIDS epidemic is not at its height, but it is certainly more visible than before, and many artists register the impact of the new sensibility this medical and social emergency actually moulds. Considering a specific time span (the 90s) and focusing mostly on cinema a strategic, privileged arena where gay cultures resist to social and cultural sanctions, this work elaborates on how AIDS as a deathly social and cultural destiny has suggested strategies of mournings that introduce new artistic practices. The analysis is specifically focused on Derek Jarman's last works, culminating in the film Blue (1993).
A. Pajalich, Il bianco, il nero, il colore. Cinema dell’Impero Britannico e delle sue ex colonie (1929-1972).
Nicoletta Vallorani
Altre Modernità , 2009,
Abstract: A. Pajalich, Il bianco, il nero, il colore. Cinema dell’Impero Britannico e delle sue ex colonie (1929-1972).
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