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Search Results: 1 - 10 of 287 matches for " Nicoletta Iacovidou "
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Cord Blood Ischemia-Modified Albumin Levels in Normal and Intrauterine Growth Restricted Pregnancies
Nicoletta Iacovidou,Despina D. Briana,Maria Boutsikou,Sophia Liosi,Stavroula Baka,Theodora Boutsikou,Demetrios Hassiakos,Ariadne Malamitsi-Puchner
Mediators of Inflammation , 2008, DOI: 10.1155/2008/523081
Abstract: Ischemia-modified albumin (IMA) is a sensitive biomarker of cardiac ischemia. Intrauterine growth restriction (IUGR) may imply fetal hypoxia, resulting in blood flow centralization in favour of vital organs (brain, heart, adrenals—‘‘brain sparing effect’’). Based on the latter, we hypothesized that cord blood IMA levels should not differ between IUGR and appropriate-for-gestational-age (AGA) full-term pregnancies. IMA was measured in blood samples from doubly-clamped umbilical cords of 110 AGA and 57 asymmetric IUGR pregnancies. No significant differences in IMA levels were documented between AGA and IUGR groups. IMA levels were elevated in cases of elective cesarean section (P = .035), and offspring of multigravidas (P = .021). In conclusion, ‘‘brain sparing effect’’ is possibly responsible for the lack of differences in cord blood IMA levels at term, between IUGR and AGA groups. Furthermore, higher oxidative stress could account for the elevated IMA levels in cases of elective cesarean section, and offspring of multigravidas.
Hypoxia/reoxygenation-induced myocardial lesions in newborn piglets are related to interindividual variability and not to oxygen concentration
Faa, Armando;Iacovidou, Nicoletta;Xanthos, Theodoros;Locci, Annalisa;Pampaloni, Pietro;Aroni, Filippia;Papalois, Apostolos;Faa, Gavino;Fanos, Vassilios;
Clinics , 2012, DOI: 10.6061/clinics/2012(05)16
Abstract: objective: evaluation of myocardial histological changes in an experimental animal model of neonatal hypoxiareoxygenation. methods: normocapnic hypoxia was induced in 40 male landrace/large white piglets. reoxygenation was initiated when the animals developed bradycardia (hr <60 beats/min) or severe hypotension (map <15 mmhg). the animals were divided into four groups based on the oxygen (o2) concentration used for reoxygenation; groups 1, 2, 3, and 4 received 18%, 21%, 40%, and 100% o2, respectively. the animals were further classified into five groups based on the time required for reoxygenation: a: fast recovery (<15 min); b: medium recovery (15-45 min); c: slow recovery (45-90 min); d: very slow recovery (>90 min), and e: nine deceased piglets. results: histology revealed changes in all heart specimens. interstitial edema, a wavy arrangement, hypereosinophilia and coagulative necrosis of cardiomyocytes were observed frequently. no differences in the incidence of changes were observed among groups 1-4, whereas marked differences regarding the frequency and the degree of changes were found among groups a-e. coagulative necrosis was correlated with increased recovery time: this condition was detected post-asphyxia in 14%, 57%, and 100% of piglets with fast, medium, and slow or very slow recovery rates, respectively. conclusions: the significant myocardial histological changes observed suggest that this experimental model might be a reliable model for investigating human neonatal cardiac hypoxia-related injury. no correlation was observed between the severity of histological changes and the fio2 used during reoxygenation. severe myocardial changes correlated strictly with recovery time, suggesting an unreported individual susceptibility of myocardiocytes to hypoxia, possibly leading to death after the typical time-sequence of events.
Perinatal Changes of Cardiac Troponin-I in Normal and Intrauterine Growth-Restricted Pregnancies
Nicoletta Iacovidou,Maria Boutsikou,Demetrios Gourgiotis,Despina D. Briana,Stavroula Baka,Venetia-Maria Vraila,Louiza Kontara,Demetrios Hassiakos,Ariadne Malamitsi-Puchner
Mediators of Inflammation , 2007, DOI: 10.1155/2007/53921
Abstract: Intrauterine growth restriction (IUGR) implies fetal hypoxia, resulting in blood flow redistribution and sparing of vital organs (brain, heart). Serum cardiac Troponin-I (cTnI), a well-established marker of myocardial ischaemia, was measured in 40 mothers prior to delivery, the doubly clamped umbilical cords (representing fetal state), and their 20 IUGR and 20 appropriate-for-gestational-age (AGA) neonates on day 1 and 4 postpartum. At all time points, no differences in cTnI levels were observed between the AGA and IUGR groups. Strong positive correlations were documented between maternal and fetal/neonatal values (r≥.498, P≤.025 in all cases in the AGA and r≥.615, P≤.009 in all cases in the IUGR group). These results may indicate (a) normal heart function, due to heart sparing, in the IUGR group (b) potential crossing of the placental barrier by cTnI in both groups
Le fonti slave dell’esperanto Le fonti slave dell’esperanto
Nicoletta Marcialis
Studi Slavistici , 2012,
Cooperative Hypertext: An Educational Example
Nicoletta SALA
The Turkish Online Journal of Distance Education , 2002,
La tutela del paesaggio: percorsi giuridici
Nicoletta Ferrucci
Aestimum , 2007,
Lucia Saetta e Cristina Vannini Parenti (a cura di), Blog & Nuvole. Un incontro tra la scrittura della rete e l’arte del fumetto.
Nicoletta Vallorani
Altre Modernità , 2009,
Abstract: Lucia Saetta e Cristina Vannini Parenti (a cura di), Blog & Nuvole. Un incontro tra la scrittura della rete e l’arte del fumetto.
Il Gesù di Stracci
Nicoletta Vallorani
Altre Modernità , 2010,
Abstract: Il Gesù di Stracci (Tomaso Subini, Pier Paolo Pasolini. La ricotta, Torino, Lindau, 2009, pp.221, ISBN 978-88-7180-814-7) di Nicoletta Vallorani
Path(o)s of Mourning. Memory, Death and the Invisible Body in Derek Jarman’s Blue
Nicoletta Vallorani
Altre Modernità , 2010,
Abstract: The essay addresses two quite complex issues. The first one is the virulence of the hostility toward gay men that the AIDS pandemic has released: this is the backdrop against which Jarman's extended elaboration and mourning for his own death is performed, after his diagnosis as body-positive in 1986. The second issue links to the open question of public mourning and its relation to AIDS in the early 90s, when the AIDS epidemic is not at its height, but it is certainly more visible than before, and many artists register the impact of the new sensibility this medical and social emergency actually moulds. Considering a specific time span (the 90s) and focusing mostly on cinema a strategic, privileged arena where gay cultures resist to social and cultural sanctions, this work elaborates on how AIDS as a deathly social and cultural destiny has suggested strategies of mournings that introduce new artistic practices. The analysis is specifically focused on Derek Jarman's last works, culminating in the film Blue (1993).
A. Pajalich, Il bianco, il nero, il colore. Cinema dell’Impero Britannico e delle sue ex colonie (1929-1972).
Nicoletta Vallorani
Altre Modernità , 2009,
Abstract: A. Pajalich, Il bianco, il nero, il colore. Cinema dell’Impero Britannico e delle sue ex colonie (1929-1972).
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