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Antistreptolysin O titer in health and disease: levels and significance
Alyaa Amal Kotby,Nevin Mamdouh Habeeb,Sahar Ezz El Arab
Pediatric Reports , 2012, DOI: 10.4081/pr.2012.e8
Abstract: Over diagnosis of acute rheumatic fever (ARF) based on a raised antistreptolysin O titer (ASOT) is not uncommon in endemic areas. In this study, 660 children (aged 9.2 ±1.7 years) were recruited consecutively and classified as: G1 (control group, n=200 healthy children), G2 (n=20 with ARF 1st attack), G3 (n=40 with recurrent ARF), G4 (n=100 with rheumatic heart disease (RHD) on long acting penicillin (LAP)), G5 (n=100 with acute follicular tonsillitis), and G6 (n=200 healthy children with history of repeated follicular tonsillitis more than three times a year). Serum ASOT was measured by latex agglutination. Upper limit of normal (ULN) ASOT (80th percentile) was 400 IU in G1, 200 IU in G4, and 1600 IU in G6. Significantly high levels were seen in ARF 1st attack when compared to groups 1 and 5 (P<0.001 and P<0.05, respectively). ASOT was significantly high in children over ten years of age, during winter and in those with acute rheumatic carditis. ASOT showed significant direct correlation with the number of attacks of tonsillitis (P<0.05). Egyptian children have high ULN ASOT reaching 400 IU. This has to be taken into consideration when interpreting its values in suspected ARF. A rise in ASOT is less prominent in recurrent ARF compared to 1st attack, and acute and recurrent tonsillitis. Basal levels of ASOT increase with age but the pattern of increase during infection is not age dependent
Therapeutic Role of Mobilized Bone Marrow Cells in Children with Nonischemic Dilated Cardiomyopathy
Nevin M. Habeeb,Omneya I. Youssef,Eman S. El Hadidi
ISRN Pediatrics , 2012, DOI: 10.5402/2012/927968
Therapeutic Role of Mobilized Bone Marrow Cells in Children with Nonischemic Dilated Cardiomyopathy
Nevin M. Habeeb,Omneya I. Youssef,Eman S. El Hadidi
ISRN Pediatrics , 2012, DOI: 10.5402/2012/927968
Abstract: Dilated cardiomyopathy is an important cause of congestive cardiac failure in infants and children. Mobilizing hematopoietic progenitor cells is a promising intervention to this deadly disease. Aim. Evaluate granulocyte colony stimulating factor (GCSF) as therapeutic modality in children with idiopathic dilated cardiomyopathy (IDCM). Subjects and Methods. This case-control prospective study was conducted on 20 children with IDCM following up at Cardiology Clinic Children's Hospital, Ain Shams University (group 1) who were compared to another 10 age-, sex-, duration-of-illness-, and systolic-function-matched children with IDCM as control (group 2). They were subjected to history taking, clinical examination, echocardiography, and peripheral blood CD34+ cell assessment before and one week after GCSF intake for 5 consecutive days (by group 1 but not group 2). Results. A significant improvement in echocardiographic data and CD34+-T-cell increase was found in group 1 one week after GCSF intake and for the next 6 months CD34+ T cells percentage of change showed no significant correlation with the that of the left ventricular dimensions and systolic function. Conclusion. Administration of GCSF to children with IDCM resulted in clinical and echocardiographic improvement not correlated to mobilized CD34+ T cells, implying involvement of additional mechanisms over simple stem cell mobilization. 1. Introduction Dilated cardiomyopathy is an important cause of chronic congestive cardiac failure in infants and children. Although a variety of etiological factors have been listed, most patients with echocardiographically documented dilated cardiomyopathy do not possess a demonstrable cause [1]. Poor myocardial function in dilated cardiomyopathy triggers a sequence of compensatory mechanisms that favor myocardial and peripheral vascular remodeling by necrosis, fibrosis, and apoptosis which ultimately do more harm than good [2]. Medical intervention will remain the cornerstone of management until advances in surgical techniques become more widely available [3]. Mobilizing hematopoietic progenitor cells to repair the failing heart is a promising intervention to halt the progression of this deadly disease. Low doses of GCSF, five microgram per kilogram per day, were found to improve systolic function in adults with advanced systolic heart failure [2]. Bone marrow stem cells were found to contribute to the regeneration of nonhaematopoietic organs. Data from preclinical models indicate that cluster of differentiation thirty-four cells restore the microcirculation and improve
Finite element study on the predicted equivalent stresses in the artificial hip joint  [PDF]
Mamdouh M. Monif
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.52007
Abstract: The subsurface fatigue that occurs in the Ultra-High Molecular Weight Polyethylene (UHMWPE) hip joint cup has been identified to be correlated with the contact stress at that cup. This cup stress is known to be affected by the implant design, dimensions and materials. In this study, a 3D finite element modeling has been used to investigate the effects on the cup contact stress when using low stiffness Titanium alloy (Ti) as a femur head. Also, the effects on the cup contact stress due to using different sizes of femur heads, and the presence of metal backing shell with different thicknesses are studied. The finite element results show that the use of low stiffness Ti alloy femur head results in a significant decrease in the cup contact stress compared with Stainless Steel (SS) and Cobalt Chromium (Co Cr Mo) femur heads. The presence of metal backing shell up to 1 mm thickness results in a remarkable decrease in the cup contact stresses especially for small femur heads. Finally, the use of larger femur heads, up to 32 mm diameter, results in significant decrease in the overall predicted hip joint contact. The present results indicate that any changes in design and geometrical parameters of the hip joint have significant consequences in the long term behaviour of the artificial hip joint and should be taken into consideration.
Acute Cholecystitis Mimics Ischemic Cardiac Disease: A Case Report and Review of the Literature  [PDF]
Osman Habeeb, Taj Eldeen Ebrahim
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.311131
Abstract: Chest pain and shortness of breath are typical indicators of cardiac problem and may lead to life threatening conditions. Nevertheless, these symptoms may also be associated with a non-cardiac condition clinically such as cholecystitis. We have reported 4 cases in a period of 6 months wherein the patients presented with cardiac-like symptom show ever; they were subsequently diagnosed with non-cardiac problems. Two patients presented with severe chest pain and shortness of breath mimicking angina pectoris. They were admitted to the intensive care unit for emergency management. The ECG findings were normal. There were two other patients who also presented with severe chest pain and shortness of breath with ST segment elevation during the ECG examination. The abdominal ultrasound in all the 4 patients showed typical features of acute calculus cholecystitis. All patients were young (30 - 36 years of age) females who were obese (BMI ranging from 30 - 34). Cholecystectomy was performed which led to improved symptoms postoperatively and ECG changes became normal.
A Short Note on Discrete Log Problem in $F_p$
Habeeb Syed
Mathematics , 2009,
Abstract: Let $p$ be a odd prime such that 2 is a primitive element of finite field $F_p*$. In this short note we propose a new algorithm for the computation of discrete logarithm in $F_p*$. This algorithm is based on elementary properties of finite fields and is purely theoretical in nature.
Structural and Crystallographic Features of Chemically Synthesized Cero- and Titanium Cero- Antimonates Inorganic Ion Exchangers and Its Applications  [PDF]
Mamdouh M. Abou-Mesalam
Advances in Chemical Engineering and Science (ACES) , 2011, DOI: 10.4236/aces.2011.11001
Abstract: Chemically synthesized cero-antimonate and titanium cero-antimonate prepared by sol-gel technique was conducted for the synthesis of a novel ion exchanger. The prepared materials has been characterized by X-ray diffraction, X-ray fluorescence, Fourier transform Infrared Spectroscopy (FT-IR) and Thermograve-metric analyses. The structures and empirical formula's was identified and found to CeSb4O12?6.19H2O and TiCeSb4O14?12.22H2O, for cero-antiomate and titanium cero-antimonate, respectively. The data obtained from X-ray diffraction was analyzed to define the crystallographic feature of cero-antimonate and titanium cero-antimonate and found both the composites were belong to cubic system with lattice constant 5.15 and 5.149 Å, respectively. The crystallite size and strain of cero-antimonate and titanium cero-antimonate were determined. By using ChemDraw Ultra program the modeling structures of cero-antimonate and titanium cero-antimonate were conducted. Finally, application of the prepared materials for the removal of heavy metals from industrial waste water in terms of capacity measurements was performed.
Hydrothermal Synthesis and Characterization of a Novel Zirconium Oxide and Its Application as an Ion Exchanger  [PDF]
Mamdouh M. Abou-Mesalam
Advances in Chemical Engineering and Science (ACES) , 2011, DOI: 10.4236/aces.2011.11004
Abstract: A novel hydrothermal zirconium oxide (ZrO2) ion exchange material was successfully synthesized by hydrothermal technique. The material has been characterized using different tools such as thermal analysis (DTA-TGA), FT-IR and X-ray diffraction studies. The results show that the prepared ZrO2 is pure and with a unique shape and it belongs to the hexagonal system. Chemical resistively of the material for various media such as, water, acids and bases have been assessed. The capacity of ZrO2 ion exchanger for Na+, Cu2+, Ni2+ and Zn2+ ions at natural pH has been determined. The effect of heating treatment for ZrO2 on ion exchange capacity was studied. The sorption/ion exchange behaviour of Cu2+, Ni2+ and Zn2+ ions towards ZrO2 in dif-ferent pH media has been investigated. The distribution coefficients and separation factors were determined. Finally, Freundlich isotherms for Cu2+, Zn2+ and Ni2+ ions on hydrothermal ZrO2 ion exchanger were inves-tigated and the Freundlich isotherm constants were conduced.
Creating futures between Interaction Design and Medicine
Antony Nevin
Australasian Medical Journal , 2010,
The Effects of the Recent Legal Arrangements Concerning the Wholesale Markets on Actors within the Fruit-Vegetable Marketing Chain: The Case of Izmir, Turkey
Nevin Demirbas
Journal of Applied Sciences , 2005,
Abstract: In this study, the effects of the recent legal arrangements concerning the fruit-vegetable wholesale markets in Turkey have been analysed through surveys, especially on various sectors in fruit-vegetable production and marketing in zmir province. In the study, first of all, the place and importance of wholesale markets within the fresh fruit-vegetable marketing system and then the changes caused by the legal arrangements were discussed. In zmir province, as a result of the surveys carried out with fruit-vegetable producers, managers and mediators at the wholesale markets and chambers and associations of retailers, problems in the application of recent legal arrangements were determined. Furthermore, precautions that need to be taken to solve the problems were also discussed.
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