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Search Results: 1 - 10 of 8293 matches for " Neeraj Sharma "
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Primary Oral Malignant Melanoma: Two Case Reports and Review of Literature
Neeraj Sharma
Case Reports in Dentistry , 2012, DOI: 10.1155/2012/975358
Abstract: Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important.
Primary Oral Malignant Melanoma: Two Case Reports and Review of Literature
Neeraj Sharma
Case Reports in Dentistry , 2012, DOI: 10.1155/2012/975358
Abstract: Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important. 1. Introduction Malignant melanoma is a potentially aggressive tumor of melanocytic origin [1]. About 1–8% of all melanomas arise in the oral mucosa [2] and these account for 0.5% of all oral malignancies [3–5]. The most frequently affected oral sites are the palate and the maxillary gingiva. The age of reported patients ranges from 20 to 80 years [1, 5]. The neoplasm is more common in Japan and Africa than in Western countries [5]. The etiopathogenesis of mucosal melanomas is poorly understood; however, it is well documented that the melanocytes migrate to both endodermally derived and ectodermally derived mucosa. The function of these melanocytes in the mucosa is not understood. Like their cutaneous counterparts, oral melanomas (OMs) are believed to arise either from nevus, preexisting pigmented areas, Hutchinson’s premalignant lentigo or denovo (30% cases) [6]. 2. Case Reports 2.1. Case 1 A dark 60-year-old male patient visited the Department of Oral Medicine and Radiology with a chief complain of recurrent growth in the lower front region since 20 days. The patient gave a history of excision of similar growth about eight months back. The treatment details and the histopathology reports were not available. The patient gave a history of smoking and alcohol use. Medical history was noncontributory. Extra-oral examination revealed no apparent lymph node enlargement. Intraoral examination showed an exophytic growth of 2.5 × 4?cm approximately on the lingual aspect of mandibular anterior region, extending from the mandibular right lateral incisor upto the left second premolar. The growth was pedunculated, arising from the marginal and attached gingiva of mandibular left incisors and canine. It is well defined, firm, nontender and covered with white pseudomembrane (Figure 1). Removal of the pseudomembrane revealed blackish underlying surface. Mandibular marginal and attached gingiva was black in color especially on the labial/buccal aspect (Figure 2). Multiple satellite lesions could be seen on the floor of the mouth. Correlating all the clinical features a diagnosis of malignant melanoma was made. Figure 1: Exophytic growth seen covered with a white pseudomembrane.
Synthesis, physicochemical and antimicrobial studies of first row transition metal complexes with quinoline derivatives nitroquinolino (3,2-b)(1,5)benzodixazepine and nitroquinolino(3,2-b)(1,5)benzoxazepine
Neeraj Sharma,Neelam Sharma
Orbital : the Electronic Journal of Chemistry , 2011,
Abstract: div align="justify">Metal complexes of Mn (II), Cu (II), Ni (II) & Co (II) with quinoline derivatives have been synthesized and characterized by elemental analysis, molar conductance, magnetic movement, electronic spectra, thermal analysis and IR spectral data. The molecular formula of complexes corresponds to [ML(NO3)2] where M = Mn ,Cu , Ni , Co , Zn , Fe, and Cr. The physicochemical and IR spectral data shows that the ligand coordinates to the metal ion in bidentate fashion (through the C=N and N-H groups). The antimicrobial studies of ligand and its metal, metal complexes have been screened for selected bacteria (E. Coli , S. typhi , B. subtilis and S. aureus) and fungi (A. flavous, A. niger, P. triticena and F. species). Antimicrobial studies shows that the Mn (II) complexes are more toxic than other metal complexes. Magnetic susceptibility measurements reveal octahedral geometry around the metal ion. The complexes were found to be non electrolyte in nature on the basis of low value of molar conductance.
Unusual Foreign Bodies in the Orofacial Region
Sidhi Passi,Neeraj Sharma
Case Reports in Dentistry , 2012, DOI: 10.1155/2012/191873
Abstract: Foreign bodies may be deposited in the oral cavity either by traumatic injury or iatrogenically. Among the commonly encountered iatrogenic foreign bodies are restorative materials like amalgam, obturation materials, broken instruments, needles, and so forth. The discovery of foreign bodies in the teeth is a special situation, which is often diagnosed accidentally. Detailed case history, clinical and radiographic examinations are necessary to come to a conclusion about the nature, size, location of the foreign body, and the difficulty involved in its retrieval. It is more common to find this situation in children as it is a well-known fact that children often tend to have the habit of placing foreign objects in the mouth. Sometimes the foreign objects get stuck in the root canals of the teeth, which the children do not reveal to their parents due to fear. These foreign objects may act as a potential source of infection and may later lead to a painful condition. This paper discusses the presence of unusual foreign bodies—a tip of the metallic compass, stapler pin, copper strip, and a broken sewing needle impregnated in the gingiva and their management.
Anaesthetic Management of Scimitar Syndrome: A Case Report
Ajmer Singh,Neeraj Sharma
Indian Anaesthetists' Forum , 2010,
Abstract: Scimitar syndrome, a rare congenital cardiopulmonary anomaly, consists of partial anomalous pulmonary venous connection of the right lung to the inferior vena cava, right lung hypoplasia and anomalous systemic arterial supply to the right lung. A 5 month old child with scimitar syndrome and pulmonary hypertension, underwent stenting of anomalous pulmonary vein, and coil embolization of systemic collateral artery to the right lung. Surgical ligation of large patent ductus arteriosus was performed to further decrease pulmonary artery pressure. Child was discharged after a successful combined therapy of surgical and transcatheter intervention.
Lymphoid aggregates in bone marrow biopsies in patients with hypereosinophilia
Sharma Seema,Dhameja Neeraj
Indian Journal of Pathology and Microbiology , 2008,
Abstract:
EFFECT OF DIFFERENT CARBON AND NITROGEN SOURCES ON α- AMYLASE PRODUCTION FROM BACILLUS AMYLOLIQUEFACIENS
Neeraj Sharma et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: Amylases are among the most important enzymes in present-day biotechnology. The effects of various carbon and nitrogen sources on α-amylase production by submerged fermentation (smF) from Bacillus amyloliquefaciens was investigated. The study revealed that the levels of the α- amylase production varied greatly with the type and concentration of carbon and nitrogen sources used. The highest α-amylase production was obtained in medium supplemented with lactose at 5g/l concentration. The other carbon sources like sucrose and mannitol also favored the α-amylase production. Maximum enzyme production was found with Ammonium chloride (NH4Cl) as the nitrogen source at 6g/l concentration. Yeast extract and peptone also seems to be suitable for the production of α-amylase from Bacillus amyloliquefaciens.
Automated medical image segmentation techniques
Sharma Neeraj,Aggarwal Lalit
Journal of Medical Physics , 2010,
Abstract: Accurate segmentation of medical images is a key step in contouring during radiotherapy planning. Computed topography (CT) and Magnetic resonance (MR) imaging are the most widely used radiographic techniques in diagnosis, clinical studies and treatment planning. This review provides details of automated segmentation methods, specifically discussed in the context of CT and MR images. The motive is to discuss the problems encountered in segmentation of CT and MR images, and the relative merits and limitations of methods currently available for segmentation of medical images.
Unusual Foreign Bodies in the Orofacial Region
Sidhi Passi,Neeraj Sharma
Case Reports in Dentistry , 2012, DOI: 10.1155/2012/191873
Abstract: Foreign bodies may be deposited in the oral cavity either by traumatic injury or iatrogenically. Among the commonly encountered iatrogenic foreign bodies are restorative materials like amalgam, obturation materials, broken instruments, needles, and so forth. The discovery of foreign bodies in the teeth is a special situation, which is often diagnosed accidentally. Detailed case history, clinical and radiographic examinations are necessary to come to a conclusion about the nature, size, location of the foreign body, and the difficulty involved in its retrieval. It is more common to find this situation in children as it is a well-known fact that children often tend to have the habit of placing foreign objects in the mouth. Sometimes the foreign objects get stuck in the root canals of the teeth, which the children do not reveal to their parents due to fear. These foreign objects may act as a potential source of infection and may later lead to a painful condition. This paper discusses the presence of unusual foreign bodies—a tip of the metallic compass, stapler pin, copper strip, and a broken sewing needle impregnated in the gingiva and their management. 1. Introduction Self-inflicted injuries are not uncommon [1, 2] and range in severity from simple nail biting to more extreme forms of mutilation, with oral trauma sometimes being the only presenting manifestation. Although the typical clinical features of oral self-injurious behaviour are well documented [3–5], they often present a difficult diagnostic problem for the clinician and, even when recognized, the method of their development and their management are not clearly understood. Foreign bodies may be ingested, inserted into a body cavity, or deposited into the body by a traumatic or iatrogenic injury. Most foreign bodies cause abscess formation, septicemia, or lead to severe haemorrhage; they can also undergo distant embolization [6]. Foreign bodies and tissue reactions to foreign materials, are commonly encountered in the oral cavity. The more common iatrogenic lesions include apical deposition of endodontic materials, mucosal amalgam and graphite tattoos, myospherulosis, oil granulomas, and traumatically introduced dental materials and instruments [7]. Injury to both the hard and soft tissues may occur as a consequence of child’s habit of placing foreign objects into the mouth. Foreign objects may become a potent source of pain and infection. The chance of these foreign objects getting impacted into the tooth is more when the pulp chamber is open either because of traumatic injury or a large carious
Efficient cache oblivious algorithms for randomized divide-and-conquer on the multicore model
Neeraj Sharma,Sandeep Sen
Computer Science , 2012,
Abstract: In this paper we present randomized algorithms for sorting and convex hull that achieves optimal performance (for speed-up and cache misses) on the multicore model with private cache model. Our algorithms are cache oblivious and generalize the randomized divide and conquer strategy given by Reischuk and Reif and Sen. Although the approach yielded optimal speed-up in the PRAM model, we require additional techniques to optimize cache-misses in an oblivious setting. Under a mild assumption on input and number of processors our algorithm will have optimal time and cache misses with high probability. Although similar results have been obtained recently for sorting, we feel that our approach is simpler and general and we apply it to obtain an optimal parallel algorithm for 3D convex hulls with similar bounds. We also present a simple randomized processor allocation technique without the explicit knowledge of the number of processors that is likely to find additional applications in resource oblivious environments.
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