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Search Results: 1 - 10 of 91803 matches for " Ne?i? Dragan "
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Low polyphase fluvial levels of the river Crni Timok in the basin of Zaje ar
Glasnik Srpskog Geografskog Dru?tva , 2004, DOI: 10.2298/gsgd0401029n
Abstract: The problem of origin and extension of the river terrace in Serbian valleys has been dealt with by many explorers. Beside those extensive investigations, this problem has not been explained enough. Therefore, more detailed investigations of river terraces were taken on a smaller region in the valley of the river Crni Timok in the basin of Zaje ar (the Eastern Serbia). A series of low river terraces (the first terrace of r.h. 3-5 m the second terrace of r.h. 5-10 m, the third terrace of r.h. 10-16 m and the forth terrace of r.h. 20-30 m) and two special levels (inundation level of r.h. 0-2 m and the level of low shelves of r.h. 2-4 m) were set aside on this tract. This series of low river terraces of the river Crni Timok brought about the idea of the cyclic origin of some terrace series, which is to be tested by future explorations.
The results of the speleological and speleoclimatic explorations of the great ice-cellar on Devica and of the ice-cellars of Rtanj and Tupiznica
Glasnik Srpskog Geografskog Dru?tva , 2002, DOI: 10.2298/gsgd0202045n
Abstract: The Great ice-cellar on Devica and the ice-cellars of Rtanj and Tupiznica are karst pits of the Karpatho-Balkan mountain system of the Eastern Serbia. These are specific speleological objects with the static ice-cellar characteristics and that implies the permanent retaining of the cold pit air without any circulation and also periodical duration of ice and snow. The climatic features of these pits are conditioned by their morphological characteristics and by the mountain climate. Our speleoclimatic explorations have pointed out to some smaller daily and somewhat bigger annual swayings of pit air temperature. These annual swaying influence the appearance and melting of ice and the absence of the air circulation between the pit and the outside in the warmer part of the year, while during the winter this circulation is present. Morphologically, these ice-cellars belong to the type of common oblique pits, while morphogenetically they are of tectonic-karst base.
The problem of the presence of relict cryoplanation morphology on mountain Tupi nica (Eastern Serbia)
Glasnik Srpskog Geografskog Dru?tva , 2010, DOI: 10.2298/gsgd1004045n
Abstract: During several-year long research on Tupi nica (1160 m), a low limestone mountain in eastern Serbia, some terraces, cirque niches and other occurrences and forms in the highest parts of mountain with unfamiliar genetic origin have been registered. Using the complex analysis of this morphology, and relying on the achievements of contemporary geomorphology, we have come to conclusion that the aforementioned terraces resemble relict periglacial, or, cryoplanation relief, which has been taken from the fact that Tupi nica was in its Last Glacial Maximum with its highest parts in the zone of mountainous periglacial environment. Considering the fact that this morphology is registered on a low mountain, the aim of this paper is to prove the given assumption and solve this problem.
Speleological exploration results for Kamena Gora and Petnja, SW Serbia
NeiDragan,Rabrenovi? Milan
Glasnik Srpskog Geografskog Dru?tva , 2011, DOI: 10.2298/gsgd1102029n
Abstract: Speleomorphological exploration in the Kamena Gora village area and Petnja depression, parts of the Jabuka-Babine plateau bordering on Montenegro in the extreme SW of Serbia, is described in this paper in the sections on morphology, survey methods and general speleomorphologic and morphogenetic features of caves. The results of particular note are the two cave systems in Petnja depression: the Petnja Caves 551 m long and the Kurtova Jama system 650 m long, the latter probably being one of major speleologic features in Serbia. The big and small Mujova Caves and Bezdan are the three caves explored in Kamena Gora. The exploration should be continued at a general survey level.
Treatment of subacute hepatitis B with lamivudine: A pilot study in Serbia
Deli? Dragan,Nei? Zorica,Prostran Milica,Bori?i? Ivan
Vojnosanitetski Pregled , 2009, DOI: 10.2298/vsp0903199d
Abstract: Background/Aim. The incidence of acute hepatitis B viral (HBV) infection in adults has increased in recent years in Serbia. Most icteric patients with acute hepatitis B resolve their infection and do not require treatment. Fulminant hepatitis B is a severe form of acute infection complicated by encephalopathy and liver failure. Subgroups of fulminant hepatitis B including hyperacute, acute and subacute are defined by the interval between jaundice and encephalopathy. Fulminant hepatic failure or subacute hepatitis B infection we observed in about 1% of all cases. In cases of fulminant hepatic failure or subacute form of HBV infection orthotopic liver transplantation can be life-saving operation, but in our country this procedure is difficult to achieve. Lamivudine has been established as a safe and effective antiviral agent for the treatment of chronic HBV hepatitis. Methods. In our pilot study performed at the Institute of Infectious and Tropical Diseases in Belgrade, Serbia in the period between 2002 and 2006 we treated 10 patients with clinically verified subacute HBV infection with lamivudine, 100 mg orally per day. Results. The most of the treated patients (9/10; 90%) survived subacute form of hepatitis B. After a few weeks of the treatment serum aminotransferase levels and other liver-function tests were normalized. Also, after a four-month lamivudine treatment all the patients lost HBsAg. Lamivudine was discontinued after six months in all the patients. In addition, six months after lamivudine was discontinued the patients remained well with normal results on liver-function tests. Conclusion. The obtained results suggest significant efficacy of lamivudine in patients with subacute hepatitis B. Also, we suggest that lamivudine therapy should be administered early in progression of subacute disease since it could be life-saving treatment in some patients, especially in the countries (like Serbia) where orthotopic liver transplantation is difficult to achieve.
Histopathology of chronic hepatitis C in relation to virus genotype
Deli? Dragan,Nei? Zorica,Prostran Milica,Bori?i? Ivan
Vojnosanitetski Pregled , 2006, DOI: 10.2298/vsp0609819d
Abstract: Background/aim: The natural history of hepatitis C virus (HCV) infection is variable and the factors determining the course of the illness are unclear. There are geographical variations in the distribution of different HCV genotypes, and some of them are related to the specific infection routes. Regarding our country, the dominant genotype is genotype 1b. It is unclear and still remains a question whether the distinct histopathological manifestations are related to the particular genotypes of HCV. Thus, the aim of this study was to determine whether the distinct histopathological manifestations of HCV infection might be in relation to the individual virus genotype. Methods. In this study we examined 126 patients with chronic HCV infection regarding the histopathological features, demographic data, and virus genotype. The observed groups of patients were predominantly infected with HCV genotypes 1b and 3a. Results. In this study we found that the patients infected with HCV genotype 1b had more frequently moderate or severe necroinflammatory activity of the disease, significantly higher grading score as compared with other genotypes (p < 0.0001). A higher degree of fibrosis was, also, more common in the patients infected with genotype 1b of HCV as compared with other genotypes (p < 0.05). There were no significant correlations between the necroinflammatory activity of the disease and the stage of fibrosis in 1b, 4 and mixed genotypes. Conclusion. The present data support the hypothesis that distinct genotypes of HCV are associated with the particular histopathological manifestation of the disease.
Treatment of anicteric acute hepatitis C with peginterferon alpha-2a plus ribavirin
Deli? Dragan,Nei? Zorica I.,Prostran Milica ?.,Simonovi? Jasmina
Vojnosanitetski Pregled , 2005, DOI: 10.2298/vsp0511865d
Abstract: Background. Hepatitis C virus (HCV) infection is the most frequent cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma in the world. Acute hepatitis C is the most commonly asymptomatic liver disease with the development of chronic HCV infection in the majority of infected patients. Studies of the natural history of HCV infection suggest that only 15-30% of patients with acute infection recover spontaneously. Others, up to 85% of the infected patients develop chronic hepatitis C. Acute hepatitis C is so uncommon and with the unpredictable occurrence, and of the low frequency, that it is difficult to determine the optimal treatment of this disease. There have been many randomized, controlled trials of the therapy in patients with chronic hepatitis C, but none of an adequate size or rigor in patients with acute hepatitis C. Therefore, the causal treatment of patients with acute hepatitis C aimed at the prevention of chronic liver disease is necessary. Case report. We have treated a patient with anicteric form of acute hepatitis C after a three-month outpatient follow-up using a combined therapy: pegylated interferon-alpha 2a, 180 μg, subcutaneously, once a week plus ribavirin 1000 mg orally once a day. The treatment lasted 24 weeks. Stable biochemical and virological response was achieved both at the end of the treatment and 6 months after the completion of the therapy. Conclusion. We believe that the above mentioned might be one of the approaches to the treatment of acute hepatitis C. However, further prospective studies with significantly larges number of patients are necessary for the definite conclusions about the treatment of HCV infections.
Periglacial relief of Crnook (southeast Serbia)
NeiDragan,Belij Sr?an,Milovanovi? Bo?ko
Glasnik Srpskog Geografskog Dru?tva , 2012, DOI: 10.2298/gsgd1201071n
Abstract: This paper presents the results of geomorphological research of the periglacial relief on mountain Crnook (1881 m) in Southeast Serbia. The results have showed the significant presence of modern periglacial morphology on this mountain which is developing in azonal conditions of a periglacial mountain environment. Research results from Crnook are significant because they represent the continuation of similar studies on medium-high mountains of Serbia (Kopaonik, Stara Planina). Based on a comparison of data from Kopaonik, Stara Planina and Crnook (Ne i D., Milin i M., 2004; Belij S. et al., 2008; Ne i D. et al., 2009; Ne i D., 2009), it can be concluded that in similar climatic frameworks with a significant share of anthropogenic activities, in terms of reducing the forest area in the highest parts of a mountain, similar modern periglacial processes develop on mountains as an indicator of azonal or boundary development framework of modern mountain periglacial environment. During 2006-07, the project "Modern periglacial geomorphic landforms on the mountains of Serbia" was initiated and the field research was conducted on the high mountains of Serbia (Stara Planina, Kopaonik, Ku aj, Beljanica, Zlatibor), and the mountains of Southeast Serbia (Vardenik, Besna Kobila, Dukat i Crnook).
Mechanism of genesis of sliding block fields on the south slope of Pan i 's peak (2017 m), Kopaonik
NeiDragan,Belij Sr?an,Milovanovi? Bo?ko
Glasnik Srpskog Geografskog Dru?tva , 2009, DOI: 10.2298/gsgd0904037n
Abstract: nema
Chronic hepatitis C virus infection: Is there a correlation between HCV genotypes and the level of viremia?
Deli? Dragan,Nei? Zorica,Simonovi? Jasmina,?virtlih Neda
Medicinski Pregled , 2006, DOI: 10.2298/mpns0606230d
Abstract: Introduction. Hepatitis C virus (HCV) RNA status and HCV genotypes have become extremely important for exact diagnosis, prognosis, duration of treatment and monitoring of antiviral therapy of chronic HCV infection. Material and methods. For the purpose of precise and objective assessment of virologic analyses, such as the determination of the number of virus copies and virus genotypes, 110 patients with chronic HCV infection were tested. Genotyping of HCV isolates and HCV RNA quantification were performed by using the PCR method. Genotype lb infection was verified in 49.1% of patients, genotype 3a infection was found in 28.2%, genotype 4 in 9.1%, genotype 2 in 4.5%, while mixed genotype infections were diagnosed in 9.1% of cases. Results. Patients infected by genotype lb had significantly higher serum HCV RNA level in relation to patients infected by other genotypes (p<0.05). Over 70% of patients infected by genotype lb had more than 2xl06 virus copies in 1 ml of blood, while in genotypes 2, 3a and 4, the percentage was 40%, 38.5% and 30%, respectively. Male patients had approximately 7.7x10.6 virus copies in 1 ml of blood, which was significantly higher in comparison with female patients (2.3xl06 copies/ml; p<0.05). Conclusion. Our results are in concordance with the results of other authors reporting that genotype lb is predominant in Europe, as well as significantly higher incidence of viremia in patients with genotype lb infection in relation to other HCV genotypes. Based on these results, we can conclude that our patients, most commonly, present with severe clinical course of chronic HCV infection and require longer treatment (48 weeks), which causes economic problems. .
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