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Search Results: 1 - 10 of 3343 matches for " Ndiangui Francis "
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Desmoid Tumour of the Brachial Plexus
Orege Juliette,Koech Florentius,Ndiangui Francis,Benson Ndegwa Macharia,Mbaruku Neema
Case Reports in Surgery , 2013, DOI: 10.1155/2013/575982
Abstract: Desmoid tumours of the brachial plexus are rare and may occur in extra-abdominal sites. The tumours are of fibroblastic origin and, although benign, are locally aggressive. Their relationship to critical neurovascular structures in their anatomic locations presents a challenge to the operating surgeons trying to adhere to the principles of surgery. Surprisingly little neurosurgical literature exists which was devoted to this topic despite the challenge these lesions present in surgery both at surgery and in choosing adjuvant therapies. We report a case of a large brachial plexus tumour in a patient which was diagnosed radiologically and histopathologically and the patient underwent surgical excision with good outcome. Desmoid tumours histologically are benign and are usually composed of proliferating, benign fibroblasts in an abundant matrix of collagen. They do not transform into malignant tumours or metastasize. Surgery is the mainstay of treatment; however, adjuvant radiation and chemotherapy remain controversial. 1. Introduction Many terms have been used to refer to desmoids tumours over the years, including fibromatosis, desmoid tumors, and aggressive fibromatosis. However, “Desmoid-type fibromatosis” has emerged as the designation of choice by the World Health Organization [1]. A review of the literature identified three case series reporting the treatment of desmoids tumours involving the brachial plexus. The first series, reported by Binder et al. [2] in June 2004, served to ascertain the rarity of these tumours. Twenty-four patients were treated at the University of California, San Francisco, CA, USA, who had primary brachial plexus tumours and only one (4%) had a desmoid tumour. The second case series reported by Seinfeld et al. [3] in 2006 included four cases of desmoid-type fibromatosis involving the brachial plexus. This series additionally assessed these lesions for mutations in the c-KIT oncogene in hopes of establishing a basis for predicting which of these lesions would respond to the chemotherapy agent imatinib mesylate. In the third case series, Dafford et al. [4] in June 2007 undertook a retrospective study of 15 desmoid tumors in 11 women and four men (ranging in age from 32 to 67 years; median 48 years) treated at their institution. In this study, the results were that there were 13 patients (86%) with brachial plexus lesions. In this review, we document the clinical presentation, neuroimaging, surgical, and pathological findings in a patient with a desmoid tumour arising from the brachial plexus. 1.1. Age and Gender Incidences of
Multiple Intracranial Meningiomas: A Review of the Literature and a Case Report
F. Koech,J. Orege,F. Ndiangui,B. Macharia,N. Mbaruku
Case Reports in Surgery , 2013, DOI: 10.1155/2013/131962
Abstract: Multiple intracranial meningiomas are a condition where there is more than one meningioma in several intracranial locations in the same patient without signs of neurofibromatosis. Incidence varies from 1 to 10%. The prognosis of multiple intracranial meningioma does not differ from benign solitary meningiomas despite the multiplicity. However, the simultaneous occurrence of different grades of malignancy is observed in one-third of multiple meningiomas. Surgery remains the best option for treatment of symptomatic lesions. Our case review aims to present and discuss a 75-year-old female patient diagnosed with multiple intracranial meningiomas, describing their clinical, radiological, histological characteristics. It also highlights the fact that the patient had two tumours, underwent surgery, and so far has a good quality of life. 1. Introduction Cushing and Eisenhardt [1] in 1938 were the first to coin the term meningioma. They came up with what closely resembles our contemporary understanding of the frequency of meningiomas by location. They defined multiple meningiomas as “at least two spatially separated meningiomas in a patient without signs of neurofibromatosis” [1]. The incidence of multiple meningiomas, defined by Cushing and Eisenhardt, is about 1 to 2 percent of all meningioma cases, and these results are comparable to those obtained by other authors [1]. 2. Case Report A 75-year-old female patient presented with a six-month history of global headaches, loss of balance, and a change in facial sensation. She had no stigmata of neurofibromatosis. Central nervous system examination revealed reduced sensation on the left side, a GCS of 15/15, and all other cranial nerves were otherwise normal. Contrast enhanced CT scans (Figure 1) revealed two intracranial lesions, one in the left cerebellopontine angle (CPA) and another in the tuberculum sella area. T1W, T2W, and FLAIR magnetic resonance imaging scans (MRI) sequences showed hyperintense well circumscribed lesions in the left CPA and tuberculum sella (Figures 2(a) and 2(b)). The left infratentorial-CPA tumour showed significant mass effect. The MRI features of the two lesions were highly suggestive of multiple meningiomas. The patient was seen in the neurosurgery clinic and was scheduled for suboccipital craniotomy of the CPA tumour. This was removed achieving Simpsons Grade 2. The tuberculum sella lesion was not excised based on the age of the patient, small size of the tumour, and its lack of symptoms. Histological examination of the cerebellopontine lesion revealed a lesion composed of many
Effect of Asian Dust Storms on the Ambient SO2 Concentration over North-East India: A Case Study  [PDF]
Timmy Francis
Journal of Environmental Protection (JEP) , 2011, DOI: 10.4236/jep.2011.26090
Abstract: Ambient SO2 concentration at a high rain fall site, Shillong (25.67oN, 91.91oE, 1064 m ASL), located in North-East India, was measured during March 2009 and January 2010 with the aim to understand the effect of long range transport of pollutants from North-East Asia on the ambient SO2 levels at this relatively clean site. The concentrations recorded during the former sampling period were very high (Max: 262.3 ppb)—which decayed down gradually towards the end the sampling period—whereas those during the latter sampling period were well within the acceptable limits (Max: 29.7 ppb). This elevated SO2 concentrations during March 2009 is proposed to have association with a major cold air outbreak and an associated cyclone preceding one of the dust storm events reported in China, and a resultant sudden change in wind trajectory leading to the long range transport of pollutants to the sampling site. The argument is formulated on the basis of the back trajectory analysis performed using HYSPLIT for the month of March 2009—the plots clearly showed a drastic change in wind trajectories between 8th and 15th of March 2009 wherein the winds traveled over some of the highly polluted regions such as the Perm region of Russia—and on the results from model runs performed using the global 3-D model of tropospheric chemistry, GEOS-Chem (v8-03-01)—it clearly showed the tropospheric SO2 over Perm region in Russia peaking during Nov, Dec, Jan, Feb and Mar every year, possibly due to central heating. The observation of long range transport of SO2 from the highly industrialized areas of Perm in Russia to North-East India during dust storm events has important implications to the present understanding on its relative contribution to the Asian pollutant outflow to the Pacific during spring as the GEOS-Chem model runs also showed regions in and around Russia with relatively high concentrations of atmospheric NOx, Peroxyacetyl Nitrate, Lumped Peroxypropionyl Nitrate, HNO3, HNO4,C3H8, C2H6, SO4, NH4, Inorganic Sulphur Nitrates and Lumped Alkyl Nitrate.
Temporal Trends in Ambient SO2 at a High Altitude Site in Semi-Arid Western India: Observations versus Chemical Transport Modeling  [PDF]
Timmy Francis
Journal of Environmental Protection (JEP) , 2012, DOI: 10.4236/jep.2012.37079
Abstract: Ambient sulphur dioxide (SO2) measurements have been performed at a high altitude site in the semi arid region of western India, Gurushikhar, Mt. Abu (24.6°N, 72.7°E, 1680 m ASL), during different sampling periods span over Sep-Dec 2009 and Feb-Mar 2010. A global three dimensional chemical transport Model, GEOS-Chem, (v8-03-01) is employed to generate the SO2 profile for the entire region for the different sampling months which in turn is used to explain the major features in the measured SO2 spectra via correlating with HYSPLIT generated wind back trajectories. The mean SO2 concentrations recorded at the sampling site varied for the different sampling periods (4.3 ppbv in Sep-Oct 2009, 3.4 ppbv in Nov 2009, 3.5 ppbv in Dec 2009, 7.7 ppbv in Feb 2010 and 9.2 ppbv in Mar 2010) which were found to be strongly influenced by long range transport from a source region surrounding 30°N, 75°E—the one projected with the highest SO2 concentration in the GEOS-Chem generated profiles for the region—lying only a few co-ordinates away. A diurnal cycle of SO2 concentration exists throughout the sampling periods, with the greatest day-night changes observed during Feb and Mar 2010, barely detectable during Sep-Oct 2009, and intermediate values for Nov and Dec 2009 which are systematically studied using the time series PBL height and OH radical values from the GEOS-Chem model. During the sampling period in Nov 2009, a plume transport to the sampling site also was detected when a major fire erupted at an oil depot in Jaipur (26.92°N, 75.82°E), located few co-ordinates away. Separate runs of the model, performed to study the long range transport effects, show a drop in the SO2 levels over the sampling region in the absence of transport, throughout the year with Jan to Apr seen to be influenced the lowest by long range transport while Jul and Dec influenced the highest.
Personal Identity and “Life-Here-After Poetics”: A Critique of Maduabuchi Dukor’s Metaphysics  [PDF]
Francis Offor
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.31A024

This essay examines Maduabuchi Dukor’s perspective on the African conception of man, personal identity and“life-here-after”. This is with a view to showing that although, Dukor’s views represent what obtain among some ethnic nationalities in Africa, this nevertheless does not provide a basis for generalising across the whole of Africa, as there are countless number of ethnic groups in Africa to which Dukor’s general claims may not be applicable. Given the varieties of metaphysical conceptions of man and destiny in Africa which we are yet to fully explore, and given also the inherent contradictions in some of these conceptions, which calls into questioning, the veracity of claims made therein, it will amount to a major logical error to make sweeping generalisations that would be representative of the whole of Africa. Such generalisations would remain a non-holistic, but partial representation of the African conception of man and human destiny.

For a Holistic View of Biotechnology in West and Central Africa: What Can Integrated Development Approaches Contribute?  [PDF]
Francis Rosillon
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.49112

Africa, ever on the lookout for development levers that will allow its economy to take off, is turning more and more towards technology. This is one of the possible modern avenues to success, especially the use of the biotechnologies that are so touted by Western countries. However, the hope placed in these new technologies must not hide the long-proven fact that technology alone is not enough to solve development problems. Biotechnologies do not escape this rule. Biotechnologies can be the best and the worst things for the people of Africa. Beyond their technical contributions, we must be wary of their boomerang effects and collateral damage. A country’s development is actually more complex than simply implementing technology, and in the current global environmental context a holistic vision is necessary to ensure sustainable development. In the area of water, this integrated vision emerged on the international scene during the Dublin Conference in 1992, which consecrated the principles of Integrated Water Resources Management (IWRM). More recently, the Eco-Health concept strives to combine human health and ecosystem health while incorporating a socioeconomic dimension into the health and environmental spheres. The concern to mesh human activities better with environmental protection was materialized previously, in the 1970s already, through impact studies. After presenting this set of tools in the service of a holistic approach to the environment and development, we shall see that these approaches can inspire the players when it comes to the ways they implement biotechnologies. At the end of the day, a holistic approach to biotechnologies in Africa will be facilitated by enhanced information and communication and reliance on peasant farmers’ expertise. It will have to be rooted in broader participation of the players concerned. This integration will also concern environmental and land-owning aspects, without forgetting socio-cultural acceptance of the projects and the links with health. Ultimately, it will also mean putting the human at the heart of development by taking all the richness and particularities of African society into account.

Udo Etuk on the “God of Africa”: A Response  [PDF]
Francis Etim
Open Journal of Philosophy (OJPP) , 2018, DOI: 10.4236/ojpp.2018.85041
Abstract: Some scholars like Rabbi Ini Mbebeng, Rabbi Ettah Essien and Prof Udo Etuk have argued against Ibibio nay Africans having the idea of Supreme Being identical with that of the West given their polytheistic conception of God with attendant pan-theistic proclivities. On the other hand, scholars like Idowu regard such position as anachronistic and retrogressive since African has what he calls, “diffused monotheistic” idea of God which in description and analysis is similar to that of Western typology. This article as a contribution to that debate examines Abasi as a name of the God among the Ibibio from philo-ontos-linguistic perspectives and comes to the conclusion that not only is it true that the Ibibio nay Africans in general have a superlative idea of God but that the African idea of God is more humanistic and existentially relevant than that of the West thus solving the attendant difficulties of explaining the relationship between God and the world and the issue of the problem of evil which resulted in such idea as Dues abscunditus in Western conception of God.
Metaphysics of Terrorism  [PDF]
Francis Etim
Advances in Applied Sociology (AASoci) , 2018, DOI: 10.4236/aasoci.2018.811041
Abstract: Terrorism as the calculated use of violence or the threat to violence through the employment of intimidation and violence in order to attain goals that are political, religious or ideological in nature has taken a global dimension and at alarming frequency such that any curious mind cannot afford to over look. Its persistence despite global condemnation and effort at curbing it naturally evokes curiosity regarding its root cause(s). Scholars have tried to dig out its root causes ranging from poverty, lack of education, religious fanaticism, psychological malady and political reasons and so on. Solutions however differ based on its perceived causes. The question is why terrorism has continued unabated. This paper believes that since human actions are elicited by the idea of the good then terrorism as a human act is based on a disoriented perception of the good. This disoriented perception is premised on a more primordial cause, an ontological lacuna that can be tagged a “search for meaning” which the terrorist tries to fill by his terroristic act. This gives the terrorist a sense of fulfilment and relevance. The panacea, the paper submits, is in a metaphysical deconstruction and construction of the terrorist mind-set based on an ontology called affective humanism.
Ontology of African Ritual  [PDF]
Francis Etim
Advances in Applied Sociology (AASoci) , 2019, DOI: 10.4236/aasoci.2019.91001
Abstract: African rituals, like other phenomena of African cultural heritage are usually faced with criticisms of being either superstitious, fetish, mundane or simply irrational. These criticisms, often based on certain logical criteria, have categorized the African mode of thinking as illogical, unreasonable and non-rational. Given the proclivity of the African mode of thinking of fusing the epistemological into the metaphysical, such criticism could either be excused or be regarded as a misinterpretation, misrepresentation and non-sequitur. However, the issue at stake calls for a deep examination of some of these phenomena to establish their reasonableness as veritable reality among Africans with serious existential import. One of such phenomena is ritual, which is actually pervasive as far as African existential reality is concerned. This paper examines African ritual to establish its reasonableness by establishing its ontology. The paper argues that based on African ontology, African rituals cannot be judged on the principles of Western scientific rationality but rather should be seen as a non-rational action like other human phenomenon like love or possessing rationality internal to the metaphysical beliefs that underpin the African worldview.
Analyses of Physical and Chemical Parameters in Surface Waters nearby a Cement Factory in North Central, Nigeria  [PDF]
Francis K. Meme, Francis O. Arimoro, Francis O. Nwadukwe
Journal of Environmental Protection (JEP) , 2014, DOI: 10.4236/jep.2014.510085

Water samples were collected from three stations along the water course of Oinyi River, Kogi State, Nigeria, bi-monthly for 12 months (October 2010 to September 2011). A total of 16 physical and chemical parameters (temperature, dissolved oxygen, biochemical oxygen demand, chemical oxygen demand, electrical conductivity, flow velocity, depth, nitrate, nitrite, phosphate, ammonia, pH, turbidity, total suspended solids, total dissolved solids and colour) were analyzed and results showed that pH (6.8 to 7.26), conductivity (106.0 to 211.7 μS/cm), colour (3.87 ± 0.159 Pt.Co), turbidity (14 - 22.7 NTU), total suspended solids (45 - 54 mg/l), biochemical oxygen demand (2.05 - 2.89 mg/l), chemical oxygen demand (17.19 ± 0.15 mg/l), temperature (24°C to 27°C) and depth (0.23 to 0.35 m) were significantly different across the different stations and between the months. However, total dissolved solids (52.7 to 108.8 mg/l), dissolved oxygen (6.02 to 7.01 mg/l), ammonia (0.00 to 0.02 mg·l-1), nitrite (0.01 - 0.09 mg·l-1), nitrate (0.045 ± 0.006 mg·l-1), phosphate (0.2 to 2.05 mg·l-1) and flow velocity (0.1 to 0.35 m·s-1) showed variations within the sampling stations. Maximum conductivity (211.7 μS/cm), colour (5.83 Pt.Co), turbidity (22.7 NTU), total suspended solids (54 mg/l), total dissolved solids (108.8 mg/l), nitrite (0.09

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