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Search Results: 1 - 10 of 269 matches for " Ndeye Ndack Diop "
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Evaluating Human Resource Capacity for Crop Breeding in National Programs in Africa and South and Southeast Asia  [PDF]
Ndeye Ndack Diop, Fredrick Okono, Jean-Marcel Ribaut
Creative Education (CE) , 2013, DOI: 10.4236/ce.2013.410A011

Plant breeders must keep abreast of the rapid evolution of new technologies, and also implement information management strategies that efficaciously handle the ever growing amount of data required for efficient integrated breeding. Updated training for breeders is critical to build relevant human resource capacity, particularly in developing countries whose breeding programs suffer a lack of staff with diverse expertise. The CGIAR Generation Challenge Programme is leading such a capacity-building initiative. A survey was conducted among course nominees to establish a baseline of breeder level of education, knowledge and skills in analyzing data and their involvement in molecular breeding programs. The breeders were mainly from three regions: West and Central Africa, East and Southern Africa, and South and Southeast Asia, and also included a few participants from North Africa. Many of the breeders from all the regions held or were working towards a PhD. Gender balance was low, principally in West and Central Africa, where less than 15% of the breeders were women. Between 57% and 73% of the breeders surveyed in the different regions were involved in molecular breeding projects at regional or international level. The Use of multiple software tools by individual breeders for data analysis was low for breeders from all the regions, with most using 1 - 3 packages. A lack of high data-analysis capacity will be a problem in an era where integration of genomics and phenotypic data in breeding programs is essential to efficiently deliver improved cultivars.

A SNP and SSR Based Genetic Map of Asparagus Bean (Vigna. unguiculata ssp. sesquipedialis) and Comparison with the Broader Species
Pei Xu,Xiaohua Wu,Baogen Wang,Yonghua Liu,Jeffery D. Ehlers,Timothy J. Close,Philip A. Roberts,Ndeye-Ndack Diop,Dehui Qin,Tingting Hu,Zhongfu Lu,Guojing Li
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0015952
Abstract: Asparagus bean (Vigna. unguiculata ssp. sesquipedialis) is a distinctive subspecies of cowpea [Vigna. unguiculata (L.) Walp.] that apparently originated in East Asia and is characterized by extremely long and thin pods and an aggressive climbing growth habit. The crop is widely cultivated throughout Asia for the production of immature pods known as ‘long beans’ or ‘asparagus beans’. While the genome of cowpea ssp. unguiculata has been characterized recently by high-density genetic mapping and partial sequencing, little is known about the genome of asparagus bean. We report here the first genetic map of asparagus bean based on SNP and SSR markers. The current map consists of 375 loci mapped onto 11 linkage groups (LGs), with 191 loci detected by SNP markers and 184 loci by SSR markers. The overall map length is 745 cM, with an average marker distance of 1.98 cM. There are four high marker-density blocks distributed on three LGs and three regions of segregation distortion (SDRs) identified on two other LGs, two of which co-locate in chromosomal regions syntenic to SDRs in soybean. Synteny between asparagus bean and the model legume Lotus. japonica was also established. This work provides the basis for mapping and functional analysis of genes/QTLs of particular interest in asparagus bean, as well as for comparative genomics study of cowpea at the subspecies level.
Evaluation of Early Warning Indicators of ARV Resistance to HIV in the Hospital of Tivaouane from 2008 to 2016  [PDF]
Agbogbenkou Tévi Déla-dem Lawson, Ndeye Astou Lakhe, Haby Dione, Papa Souleymane Toure, Mamadou Ba, Ndeye Biram Niang, Bernard Marcel Diop, Sylvie Audrey Diop-Nyafouna
Advances in Infectious Diseases (AID) , 2018, DOI: 10.4236/aid.2018.82007
Abstract: Introduction: HIV resistance to antiretroviral is currently a global concern, and requires increased surveillance in a context of widespread ARV treatment. Objective: To evaluate early warning indicators of HIV resistance to ARVs in the Hospital of Tivaouane (Senegal) where viral load was not routinely available. Methods: This is a cross-sectional retrospective study from 2008-2016. The etraction tool (May 2010 version) was used to analyze the EWI. Results: We collected 360 HIV positive patients followed on average for 3.57 years ± 3.02. 2009, 2010 and 2012 recorded 100% ARV prescribing rates. Throughout the study period, the percentage of patients lost to follow-up during the first 12 months of treatment was less than 20%. Virtually, all patients were still under primary ARVT over 12-month treatment. All patients (100%) withdrew their ARV drugs on time. No stock storage regarding various classes of ARVs was noted during the study period. Conclusion: At the end of this study we recommend to maintain regular follow-up of EWI, and combine it with the achievement of viral load.
Attitudes and Practices of Senegalese Dentists towards Hepatitis B  [PDF]
Massamba Diouf, Jean-Claude Guinan, Amadou Dieng, Mbatio Diop, Aida Kanouté, Abou Dramane Sanghare, Ndeye Amina Diop, Daouda Cisse, Cheikh Mamadou Mbacke Lo, Daouda Faye
Open Journal of Epidemiology (OJEpi) , 2017, DOI: 10.4236/ojepi.2017.74026
Abstract: Introduction: Hepatitis B is an infectious viral disease that causes inflammation of the liver. It is transmitted through body secretions and fluids, including genital secretions, saliva and blood. The objective of this study was to assess the attitudes and practices of dental surgeons in the face infection of Hepatitis B. Methods: This was a descriptive, cross-sectional a sample of 171 dental surgeons. Probabilistic multi-stage, stratified, and systematic sampling was used. Using a questionnaire, we gathered variables related to the attitudes and practices of dentists with respect to Hep B. Results: Nearly 22% of dentists were not vaccinated against hepatitis B virus; Compliance with the use of gloves, glasses, professional clothing, and hygiene in dental offices was not systematic. Blood exposure accidents (BEA) were common, with nearly 13% suffering from needle stick injuries, 10% from eye splashes and about 6% from sharp instruments. The majority of the actions to be taken in the event of (BEA) were disinfection in the event of sticks or injuries (52.1%) and rinsing in the event of eye splashes (66.7%). Conclusion: Dentists should be educated and informed about the need for vaccination and hygiene, sterilization, and good behaviour in case of exposure to blood.
Prevalence of Hypertension and Associated Factors in Patients Living with HIV Followed at the Ambulatory Treatment Center (CTA) of Fann National University Hospital in Dakar  [PDF]
Ndeye Fatou Ngom Gueye, Daye Ka, Alioune Badara Tall, Kine Ndiaye, Abdoul Aziz Ndiaye, Viviane Marie Pierre Cisse, Aissata Guindo, Ndeye Méry Dia Badiane, Sylvie Audrey Diop, Noel Magloire Manga, Cheikh Tidiane Ndour, Moussa Seydi
Health (Health) , 2017, DOI: 10.4236/health.2017.94052
Introduction: The efficacy of antiretroviral therapy in people living with HIV (PLHIV) has been associated with an important increase in metabolic disorders, such as hypertension (HTA). This work allowed us to estimate the prevalence of hypertension in PLHIV and to describe associated factors. Methods: A retrospective, descriptive and analytical study was carried out based on the records of people living with HIV followed at the Ambulatory Treatment Center (CTA), from January 1st 1998 to 31st, December 2014. The WHO criteria were used to diagnose hypertension. Data entry was performed using ESOPE software and data analysis was done using Epi Info software version 3.5.3. A multiple logistic regression was used to identify the risk factors associated with hypertension. Results: During the study period, 3624 patients followed at CTA were included of which 1184 patients (32.7%) had hypertension. The average age was 47. 3 years ±10.5 years, with a sex ratio of 0.7. The most common opportunistic infections at diagnosis were tuberculosis (14.9%) and oral candidiasis (15.3%). The HIV infection was advanced (stage 3 or 4 of WHO classification) for 39% of cases. Overweight and obesity was found in 19.1%. Only 17.6% were treated by protease inhibitors. Higher average age (OR:1,05; IC [1.04 - 1.05], p = 0.000001), higher average BMI (OR:5,3; IC [3.3 - 8.5], p = 0.00001), WHO clinical stage I-II (OR:1,4; IC [1.2 - 1.6], p = 0.00003), and ARV treatment (OR:2,5; IC [1.7 - 3.7], p = 0.000001) are associated with the occurrence of hypertension. Conclusion: The prevalence of hypertension was high among PLHIV and associated factors were: advanced age, high BMI, WHO clinical stages I and II and antiretroviral therapy. Hence, the interest of a systematic screening of hypertension and others cardiovascular risk factors particularly in patients under ARV antiretroviral therapy.
Oral Healthcare Renunciation and Socioeconomic Determinants  [PDF]
Mbathio Diop, Aida Kanoute, Massamba Diouf, Mamadou Lamine Guirassy, Ndeye Marème Sougou, Amadou Diaw Ndiaye, Cheikh Mouhamadou Mbacké L?, Daouda Faye, Daouda Cissé
Open Journal of Epidemiology (OJEpi) , 2018, DOI: 10.4236/ojepi.2018.83009
Abstract: The unequal access to healthcare in general and oral healthcare, in particular, is a true public health concern. Thus, it is important to assess the oral healthcare renunciation and socioeconomic determinants to take appropriate measures. A cross-sectional, descriptive population-based study of 300 households was carried out between April 28, 2016, and May 28, 2016, according to WHO’s guidelines (Protocol 1997), in Senegal adapted form. Results showed that 18.23% of householders report that their household members have foregone oral healthcare. Among those who renounced care, 51.5% did so for care costs (24.2%) or remoteness of health facilities (27.3%) reasons. Therefore, dental treatment renunciation was independently associated to income level, age, sex, marital status, and types of oral healthcare coverage. This study’s analysis shows that oral healthcare renunciation depends primarily on the financial aspect and the remoteness of health structures. Still, there are other important socio-anthropological parameters that should be investigated.
Fe-EDTA-Bisamide and Fe-ADR-925, The Iron-Bound Hydrolysis Product of the Cardioprotective Agent Dexrazoxane, Cleave DNA Via the Hydroxyl Radical
Thomas J. Magliery,Lizabeth K. Vitellaro,Ndeye Khady Diop,Rosemary A. Marusak
Metal-Based Drugs , 1997, DOI: 10.1155/mbd.1997.199
Incidence and Factors Associated with the Switch to the Second Line Antiretroviral Treatment at the Ambulatory Treatment Center (CTA) in Dakar  [PDF]
Ndeye Fatou Ngom-Gueye, Gilbert Batista, Abdoul Aziz Ndiaye, Assane Diouf, KA. Daye, Alioune Badara Tall, Awa Diouf, Kine Ndiaye, Makhtar Ndiaga Diop, Mountaga Dia, Cheikh Tacko Diop, Awa Gaye, Cheikh Tidiane Ndour, Moussa Seydi, Lamine Gueye, Bernard Marcel Diop, Papa Salif Sow
Health (Health) , 2016, DOI: 10.4236/health.2016.814154
Abstract: Introduction: Over the past years, efforts have been made to expand access to antiretroviral combinations (cART) in low-income countries. However, major concerns are noted with drug resistance emergence, as treatment failure result and need to introduce a second line treatment, more expensive and difficult to implement. The objective was to study the incidence of switch to second line, reasons for switch and risk factors using a cohort of people living with HIV in an Ambulatory Treatment Center in Dakar. Methodology: This was a cohort study of people living with HIV under cART from January 2004 to December 2013. Naive patients monitored for at least six months, regardless of their profile and regimen with baseline CD4 counts < 350 cells/mm3 were included in this study. Results: The median age of the 827 patients included was 44 [IQR = 18 - 78]. The switch to second-line treatment was observed in 72 patients (8.7%) after an average of 38.5 months of follow-up. The overall incidence rate of switch to second line of antiretroviral treatment was 1.59 per 100 persons-years. Most of changes in first-line treatment were motivated by virological failures (n = 60, 83.3%) under treatment with AZT/3TC/NVP (n = 25, 34.7%) or AZT/3TC/EFV21 (29.2%). 9.7% of switch occurred after immunological failure, 1.4% after clinical failure, 4.2% after severe toxicity and 1.4% was not documented. Predictive factors identifying failures at the end of the multivariate analysis were age < 44 years and CD4 counts below 100 cells/mm3. Conclusions: In total, CTA identified a low incidence rate of treatment failure of the first line of treatment. Associated risk factors were age < 44 years, CD4 counts below 100 cells/mm3 and high viral load at treatment initiation.
Family Planning Knowledge and Practices among Reproductive Age Women in Widou Thiengoly, Louga Region, Senegal  [PDF]
Abdoul Aziz Ndiaye, Niang Aminata, Tall Alioune Badara, Diop-BA Awa, Ngom-Gueye Ndeye Fatou, Dia Mountaga, Bop Martial Coly, Gaye Awa, Gueye Lamine, Tal-Dia Anta
Advances in Reproductive Sciences (ARSci) , 2018, DOI: 10.4236/arsci.2018.61001
Abstract: Family planning is an effective intervention to improve the health of the mother, newborn and child. It was introduced in Senegal in the 1960s. Significant disparities were noted between urban and rural areas. This research aimed at measuring family planning methods knowledge and practices among reproductive age women (RAW) in the village of Widou Thiengoly, Louga region, Senegal. A descriptive and analytical cross-sectional study was carried out from 12 to 20 August 2016 and involved 150 RAW with an average age of 29.34 years. They were mostly married (98%), with a fertility rate of 3.22 children/woman. 67.3% of RAW knew at least one FP method and the contraceptive prevalence was 40.7%. Birth spacing is the main reason or utilization for more than half of users, while for non-users, more than half were ignorant of FP. Knowledge and practices of contraception were not related to the age of WCA, or the number of children. Fears or experiences of side effects were barriers to initiation and continuous use of FP methods, hence the importance of focusing awareness campaigns on alleviating fears about side effects.
Study of Factors Associated with Anemia among Women in Reproductive Age in Kolda (Senegal)  [PDF]
Tine Jean Augustin Diégane, Faye Adama, Diop Sophie, Niang Khadim, Bassoum Oumar, Leye Mamadou Moustapha Mbacke, Sougou Ndeye Mareme, Diongue Fatoumata Bintou, Diallo Amadou Ibra, Diongue Mayassine, Camara Maty Diagne, Dankoko Boubacar, Seck Ibrahima, Dia Anta Tal
Open Journal of Obstetrics and Gynecology (OJOG) , 2018, DOI: 10.4236/ojog.2018.87073
Abstract: Introduction: Anemia in women of reproductive age is a common health problem in the region of Kolda (Senegal). The objective of this research was to study the risk factors of anemia among women in reproductive age in Kolda (Senegal). Methodology: A cross-sectional, descriptive and analytical study of women in reproductive age and their households was conducted in the Kolda region between October and December 2015. This was a three-stage random sample survey. The data was collected during an individual interview. Logistic regression was used to identify the factors of this anemia. Results: In this study, 968 women of reproductive age were surveyed. The average age of women was 27 years with a standard deviation of 7.4 years. There were 10% of pregnant women, 36.3% of lactating women and 53.7% of women neither pregnant nor lactating. The average size of the households surveyed was 14 people and the 36.3% had an average economic level. The majority of households were equipped with traditional latrines (76.9%). Women were neither pregnant nor lactating in 53.7%, were uneducated in 70.7% and 81% used micronutrient-rich foods. The prevalence of anemic women was 55.2%. The factors associated with anemia in women in Kolda were the use of traditional latrines (ORa = 1.48 [1.0 - 2.1]), the woman’s pregnancy status (ORa = 5 [2.7 - 9.8]), non-education of the woman (ORa = 1.52 [1.1 - 2.0]), the existence of income-generating activity for the woman (ORa = 0.69 [0.5 - 0.9]), the processing of local products in the household (ORa = 0.5 [0.3 - 0.9]) and the use of at least one micronutrient rich food in the household (ORa = 0.73 [0.49 - 1.0]). Conclusion: The prevalence of anemia
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