oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 42 )

2018 ( 302 )

2017 ( 291 )

2016 ( 288 )

Custom range...

Search Results: 1 - 10 of 20186 matches for " Ndèye Fatou Ngom-Guèye "
All listed articles are free for downloading (OA Articles)
Page 1 /20186
Display every page Item
Diabetes and Hypertension among Patients Receiving Antiretroviral Treatment Since 1998 in Senegal: Prevalence and Associated Factors
Assane Diouf,Amandine Cournil,Khadidiatou Ba-Fall,Ndèye Fatou Ngom-Guèye,Sabrina Eymard-Duvernay,Ibrahima Ndiaye,Gilbert Batista,Papa Mandoumbé Guèye,Pape Samba Ba,Bernard Taverne,Eric Delaporte,Papa Salif Sow
ISRN AIDS , 2012, DOI: 10.5402/2012/621565
Abstract: Cardiovascular risk factors in people on antiretroviral treatment (ART) are poorly documented in resource-constrained settings. A cross-sectional study was conducted in 2009 to assess prevalence of diabetes and hypertension in a sample of 242 HIV-infected patients who had initiated ART between 1998 and 2002 in Dakar, Senegal (ANRS 1215 observational cohort). World Health Organization (WHO) criteria were applied to diagnose diabetes and hypertension. Multiple logistic regressions were used to identify factors associated with diabetes and hypertension. Patients had a median age of 46 years and had received ART for a median duration of about 9 years. 14.5% had diabetes and 28.1% had hypertension. Long duration of ART (≥119 months), older age, higher body mass index (BMI), and higher levels of total cholesterol were associated with higher risks of diabetes. Older age, higher BMI at ART initiation, and higher levels of triglycerides were associated with higher risk of hypertension. This study shows that diabetes and hypertension were frequent in these Senegalese HIV patients on ART. It confirms the association between duration of ART and diabetes and highlights the need to implement programs for prevention of cardiovascular risk factors in HIV patients from resource-constrained settings. 1. Introduction In December 2010, over five million people were on antiretroviral treatment (ART) in Sub-Saharan Africa [1]. In Senegal, this number reached 18,000 at the end of 2011, corresponding to a coverage rate of 78% [2]. The efficacy of ART has led to a significant reduction in mortality among people living with HIV [3–6], causing an increase in their life expectancy, which nevertheless remains below that of the general population [7–10]. This excess mortality is partially related to immunodepression but also organic and metabolic disorders that are not classified as AIDS [4, 11–16]. These disorders have multifactor causes. The underlying physiopathological mechanisms have not been clearly established. Nevertheless, it is recognized that they involve phenomena related to the virus [17–21], to antiretrovirals (ARVs) [22–26], and to the host [27–31]. These mechanisms contribute to noninfectious diseases including diabetes and hypertension, which are two major risk factors of cardiovascular disease and are associated with increased mortality and morbidity. Available data on prevalence and the factors associated with diabetes and hypertension have dealt with populations of varying ages and whose duration of ARV exposure varied greatly. These studies have rarely addressed
Characteristics of Liver Abscess in Department of Infectious Diseases at Fann Teaching University Hospital in Dakar, Senegal  [PDF]
Viviane Marie Pierre Cisse Diallo, Louise Fortes Déguénonvo, No?l Magloire Manga, Daye Ka, Sylvie Audrey Diop, Abdoulaye Seck, Ndèye Aissatou Lakhe, Khardiata Diallo Mbaye, Assane Diouf, Ndèye Méry Dia Badiane, Ndèye Fatou Ngom Guèye, Cheikh Tacko Diop, Masserigne Soumaré, Cheikh Tidiane Ndour, Moussa Seydi
Advances in Infectious Diseases (AID) , 2018, DOI: 10.4236/aid.2018.81004
Abstract: Introduction: Abscesses of the liver are due to an infection of bacterial, parasitic or fungal origin. Through amoebiological imaging and serology, their diagnosis was facilitated. The aim of this study was to determine the epidemiological, clinical, diagnostic and evolutionary aspects of these liver abscesses at the Department of Infectious and Tropical Diseases in Fann Teaching University Hospital. Patients and Methods: This was a retrospective and descriptive study, based on records of patients hospitalized for abscess of the liver over a period of 8 years, from January 1, 2008 to December 31, 2015. Results: We collected 20 cases of abscesses including 12 cases of confirmed amoebic abscesses and 5 cases of pyogenic abscesses. The mean age of the patients was 43.15 ± 15.12 years. There were 18 men and 2 women. The average hospital stay was 32 days. The most common clinical signs were abdominal pain (100%), fever (75%), hepatomegaly (80%). A leukocytosis greater than 12,000 Gb/mm3 was found in 13 patients. The amoebic serology was positive in 71% of cases and negative in 29% of cases. No germ was isolated from the blood culture. On hepatic ultrasound the abscess was unique in 90%. Treatment was exclusively medical in 11 patients (55%). The trend was favorable in 85% of cases. Conclusion: The incidence of liver abscesses has significantly decreased. It is important to develop diagnostic tools better in the case of pyogenic abscesses.
Reduced Quantitative Ultrasound Bone Mineral Density in HIV-Infected Patients on Antiretroviral Therapy in Senegal
Amandine Cournil, Sabrina Eymard-Duvernay, Assane Diouf, Claire Moquet, Julie Coutherut, Ndèye Fatou Ngom Gueye, Cécile Cames, Bernard Taverne, Kirsten Bork, Papa Salif Sow, Eric Delaporte, for the ANRS 1215 Study Group
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0031726
Abstract: Background Bone status in HIV-infected patients on antiretroviral treatment (ART) is poorly documented in resource-limited settings. We compared bone mineral density between HIV-infected patients and control subjects from Dakar, Senegal. Methods A total of 207 (134 women and 73 men) HIV-infected patients from an observational cohort in Dakar (ANRS 1215) and 207 age- and sex-matched controls from the general population were enrolled. Bone mineral density was assessed by quantitative ultrasound (QUS) at the calcaneus, an alternative to the reference method (i.e. dual X-absorptiometry), often not available in resource-limited countries. Results Mean age was 47.0 (±8.5) years. Patients had received ART for a median duration of 8.8 years; 45% received a protease inhibitor and 27% tenofovir; 84% had undetectable viral load. Patients had lower body mass index (BMI) than controls (23 versus 26 kg/m2, P<0.001). In unadjusted analysis, QUS bone mineral density was lower in HIV-infected patients than in controls (difference: ?0.36 standard deviation, 95% confidence interval (CI): ?0.59;?0.12, P = 0.003). Adjusting for BMI, physical activity, smoking and calcium intake attenuated the difference (?0.27, CI: ?0.53;?0.002, P = 0.05). Differences in BMI between patients and controls explained a third of the difference in QUS bone mineral density. Among patients, BMI was independently associated with QUS bone mineral density (P<0.001). An association between undetectable viral load and QUS bone density was also suggested (β = 0.48, CI: 0.02;0.93; P = 0.04). No association between protease inhibitor or tenofovir use and QUS bone mineral density was found. Conclusion Senegalese HIV-infected patients had reduced QUS bone mineral density in comparison with control subjects, in part related to their lower BMI. Further investigation is needed to clarify the clinical significance of these observations.
Evaluation of Water Resources Quality in Sabodala Gold Mining Region and Its Surrounding Area (Senegal)  [PDF]
Mall Ibrahima, Diaw Moctar, Dieng Ndèye Maguette, Madioune Hélène Diakher, Ngom Papa Malick, Faye Serigne
Journal of Water Resource and Protection (JWARP) , 2015, DOI: 10.4236/jwarp.2015.73020
Abstract: Geochemical and Geostatistical tools were used to assess: 1) the chemical quality and, geochemical processes in crystalline rock aquifers in Sabodala (Eastern Senegal) and its surroundings and 2) the impact of mining activities on their quality. A total of 26 water samples collected at boreholes, dug wells and stream, were analyzed to determine major and trace elements concentration focused on elements that represent more threats on human health. Boxplots define chemical characteristics of water for each aquifer formation compared to surface waters. Geostatistical analysis show two sources of water mineralization with regard to major elements: a first natural source characterized by Ca-Mg-HCO3 water type from boreholes and unpolluted surface water and a second group characterized by polluted water by nitrates with Na-NO3-Cl type mainly observed in upper weathered aquifers. However, considering trace element, geostatistical analysis showed three water groups: water with very low trace element concentrations encountered in boreholes and unpolluted surface waters, and waters with relatively high trace element concentrations such as Al observed in areas affected by gold mining activities and finally, polluted waters by Ni, Co, Mn and Cr observed at Sabodala. Results show that in eastern Senegal well waters are vulnerable and often affected by pollution.
Effects of different inputs of organic matter on the response of plant production to a soil water stress in Sahelian region  [PDF]
Abdoulaye Badiane, Ndeye Yacine Badiane Ndour, Fatou Guèye, Saliou Faye, Ibrahima Ndoye, Dominique Masse
Natural Science (NS) , 2012, DOI: 10.4236/ns.2012.412125
Abstract: The aim was to study the effects of organic management like the application of organic matters on crop production. This research is placed in the context of climate change impact mitigation. A field experiment was conducted during the dry season. Rainfall inputs were simulated by irrigation to study the effects of water stress during the flowering period of a grain on the agronomic and the physiological behavior of the plant. The measurements were made on the volumetric soil moisture, stomatal conductance, and leaf area index (LAI), grain yield, straw and weight of 100 grains. The water use efficiency (WUE) and yield losses were evaluated. The results of the volumetric soil moisture showed that the use of localized input under water stress (STR-T1) recorded the lowest moisture in the surface horizons. Treatment with localized input under water stress with or without fertilization (STR-T1, STR-T1 + N) showed an ability of stomatal regulation compared to the control (STR- T0) and the input application by spreading (STR- T2). (STR-T1 + N) has initiated an early stomatal closure of the plant because of the effect of nitrogen. However, despite a more pronounced water stress with stomatal closure, the LAI and the grain yield were greater with (STR-T1) and (STR-T1 + N). The results showed that the inputs of localized organic fertilization with or without nitrogen grain yields were the highest regardless of the hydric regime applied. However the losses of grain yield were higher in treatments with organic inputs in spreading and localized under water stress. The WUE by the crop was reduced compared to the control with organic inputs under STR. In this study we show that the use of organic matter increases de farmers risk and this notion of risk is high and it is necessary to consider this risk in the proposals of technical innovations.
Therapeutic Aspects of Chronic Bone Infections and Management Challenges  [PDF]
Charles Diémé, Lamine Sarr, Alioune Badara Guèye, Ndeye Fatou Coulibaly, André Sané, Abdoulaye Ndiaye, Seydina Sèye
Open Journal of Orthopedics (OJO) , 2014, DOI: 10.4236/ojo.2014.42004
Abstract: This study aims to investigate various aspects of the treatment of chronic bone infections and the challenges in their management. The characterization of treatment of 73 patients with chronic bone infection was reported. The four management challenges including consultation delay, immune depression, extreme variety of clinical manifestations and non-use of CT or MRI were discussed in this study. We conducted a retrospective study at Aristide Le Dantec Hospital on 90 cases of chronic bone infection in 73 patients. The mean duration of symptoms before consultation was 36 months. More than half of the patients had a productive fistula at the first consultation. Sickle cell anemia was found in 6 patients. Multiple lesions were found in 10 patients; and long bones were affected in 90% of cases. The bacterial culture was positive in 93.15%. Staphylococcus aureus was the most isolated germ (68.35%). Seventy-two out of seventy-three patients were operated on. The procedure depended on anatomical and radiological lesions. Surgical treatment was associated with antibiotherapy which was firstly probabilistic and secondarily adapted to the results of bacterial culture. A favorable trend was found in 41 patients (56.16%). 32 cases of adverse effects were noted (43.83%), and 27 patients had recurrence after a favorable outcome. Several complications and sequelae were observed demonstrating the tenacity of these chronic infections.
Trend in Antibiotic Resistance of Streptococcus Pneumoniae and Haemophilus Influenzae Strains Isolated from Community Acquired Respiratory Tract Infections in Dakar, Senegal Between 2005 and 2008
A. Guèye Ndiaye, Hounkponou Edwige, Fatou Bintou Guèye and Cheikh Saad Bouh Boye
Microbiology Insights , 2012, DOI: 10.4137/MBI.S3819
Abstract: Development of antibiotic resistance among common respiratory pathogens is a major cause of concern worldwide. Streptococcus pneumoniae and Haemophilus influenzae are among the most common respiratory pathogens. In this study, representative samples obtained from 3 different medical centers in Dakar, Senegal were subjected to antibiotic susceptibility testing. The samples were collected from 2005 to 2008 and the data obtained was compared to establish resistance patterns between the two years (i.e. 2005–2006 to 2007–2008). S. pneumoniae exhibited a significant increase in the resistance to azithromycin and the intermediate susceptibility to penicillin G and cotrimoxazole. H. influenzae also exhibited a significant increase in resistance to azithromycin and intermediate susceptibility to chloramphenicol. None of H. influenzae samples were resistant to amoxicillin/clavulanic acid, cephalosporin and fluroquinolones and most of the S. pneumoniae isolates demonstrated high susceptibility to the antibiotics tested. Results from this study will provide greater insights to antibiotic therapy during respiratory tract infections in Dakar, Senegal. This study also establishes the importance of continuous monitoring of antibiotic susceptibility patterns that are often region-specific.
Trend in Antibiotic Resistance of Streptococcus Pneumoniae and Haemophilus Influenzae Strains Isolated from Community Acquired Respiratory Tract Infections in Dakar, Senegal Between 2005 and 2008
A. Guèye Ndiaye,Hounkponou Edwige,Fatou Bintou Guèye,Cheikh Saad Bouh Boye
Microbiology Insights , 2010,
Abstract: Development of antibiotic resistance among common respiratory pathogens is a major cause of concern worldwide. Streptococcus pneumoniae and Haemophilus influenzae are among the most common respiratory pathogens. In this study, representative samples obtained from 3 different medical centers in Dakar, Senegal were subjected to antibiotic susceptibility testing. The samples were collected from 2005 to 2008 and the data obtained was compared to establish resistance patterns between the two years (i.e. 2005–2006 to 2007–2008). S. pneumoniae exhibited a significant increase in the resistance to azithromycin and the intermediate susceptibility to penicillin G and cotrimoxazole. H. influenzae also exhibited a significant increase in resistance to azithromycin and intermediate susceptibility to chloramphenicol. None of H. influenzae samples were resistant to amoxicillin/clavulanic acid, cephalosporin and fluroquinolones and most of the S. pneumoniae isolates demonstrated high susceptibility to the antibiotics tested. Results from this study will provide greater insights to antibiotic therapy during respiratory tract infections in Dakar, Senegal. This study also establishes the importance of continuous monitoring of antibiotic susceptibility patterns that are often region-specific.
Enterobacterial Infections Diagnosed at the Clinic of Infectious Diseases of Fann Hospital (2013-2014) Dakar, Senegal  [PDF]
Khardiata Diallo Mbaye, Ndèye Aissatou Lakhe, Khadime Sylla, Rahmatoulahi Ndiaye, Viviane Marie Pierre Cissé Diallo, Daye Ka, Aminata Massaly, Alassane Dièye, Louise Fortes Déguénonvo, Cheikh Tacko Diop, Cheikh Tidiane Ndour, Masserigne Soumaré, Moussa Seydi
Advances in Infectious Diseases (AID) , 2018, DOI: 10.4236/aid.2018.84018
Abstract: Introduction: Entero bacteria are mainly found in the gut of man and animals. The frequent acquisition of antibiotic resistance mechanisms explains why they are the bacteria most often implicated in human infectious pathology. It is estimated to be involved in 50% of sepsis, 60% of enteritis, 70% of urinary tract infection case. Objective: To determine the prevalence of enterobacterial infections diagnosed at Fann Infectious Diseases Clinic, and describe their epidemiological, clinical, therapeutic and evolutionary aspects. Patients and Methods: This is a retrospective and descriptive study, on patients hospitalized from January 2013 to December 2014, at Fann Infectious Diseases Clinic, with bacteriological confirmation of an enterobacteria infection. Results: A total of 129 cases were collected during the study period. The average age was 41 years, and female were predominant (60%) with a sex ratio of 0.67. Comorbidity was found in 88.4% of the cases, most of which were HIV infection. The most common clinical signs were infectious syndrome (53.49%) and general impairment (40.31%). The main gateway was urinary (55.8%). Samples were monomicrobial in 76.7% of cases. Klebsiella and Escherichia were the most common and 68.7% of the subjects had probabilistic treatment. Most enterobacterial strains were resistant to third generation cephalosporins (C3G), aminoglycosides to ciprofloxacin and cotrimoxazole. Aside from 4% of them, all were sensitive to imipenem. Conclusion: The advent of antibiotics has brought hope in the treatment of enterobacterial infections. However, an increase in their resistance to the usual antibiotics has been noted in recent years. As a result, the fight against antibiotic resistance must be a priority.
Immunological Status to Hepatitis B Virus of Pregnant Women in Dakar, Senegal  [PDF]
Maguette Sylla Niang, Khadidiatou Sarr Fall, Babacar Mbengue, Moustapha Mbow, Ndiokhor Nd. Diouf, Ousseynou Boye, Gora Lo, Papa Madieye Guèye, Rena Derwiche, Amina Sow Sall, Tandakha Ndiaye Dieye, Alioune Dieye
Open Journal of Immunology (OJI) , 2017, DOI: 10.4236/oji.2017.72003
Abstract: Objective: Evaluate the immunological status to hepatitis B virus of Senegalese pregnant women by screening HBs antigen. Material and methods: The selection criteria of women were presence at the laboratory for biological exams of pregnancy follow-up. All volunteers for the study were screened for HBs antigen (HBs Ag). Investigation of chronic hepatitis B markers (HBe Ag, anti-HBe, viral quantification) was performed in HBs Ag positive participants. The concentration of anti-HBs antibodies was assessed in HBs Ag negative women. Results: One hundred and fifteen (115) pregnant women were included in the study from July to October 2014. The mean age was 29 ± 6 years, ranging from 16 to 47. The seroprevalence of HBs Ag was 12% and the majority of women (90%) were not vaccinated. Any of the 14 HBs Ag-positive subjects did not express serum HBe Ag, (marker of active viral replication) and all were positive for anti-HBe antibodies. Their viral load (HBV DNA) was undetectable and serum transaminases were normal. The anti-HBs antibodies titrated in HBs-Ag negative women serum revealed that only 46 had protective levels against HBV whilst 55 of them were unprotected.
Page 1 /20186
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.