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A review study on Hottentotta Birula, 1908, (Scorpionida:Buthidae) species collected from Iran
Navidpour, Sh.
Archives of Razi Institute , 2012,
Abstract: Hottentotta is one of the most widely distributed genera of the family Buthidae, with species present throughout Africa, the Arabian Peninsula, and in Asia to Pakistan and India. Recently, Kovarik (2007) revised genus of Hottentotta in the world and reported 29 different species-group name in the genus of Hottentotta. Hottentotta is one of the six medical important scorpions of Iran that distributed in almost all parts of country. So, in this article morphological and morphometrical characters of six species of Hottentotta for better distinguishing have been described.
A New Species of Psammophilic Scorpion From Iran (Scorpions: Buthidae)
S.H. Navidpour
Journal of Biological Sciences , 2008,
Abstract: In order to study the psammophilic scorpions of sandy habitats of two provinces in western and south western Iran, some samplings were carried out by night catch (UV light) method during October 2007-March 2009. In total, 187 scorpions were collected. Vachoniolus iranus is a new species of Vachoniolus, that described from Khoozestan and Ilam provinces in South-western and Western of Iran. This is first record of genus Vachoniolus from Iran.
Pedipalps and Venom Vesicle Anomalies in Two Families of Scorpions (Scorpiones: Hemiscorpiidae, Buthidae) from Iran
E. Jahanifard,Sh. Navidpour,B. Masihipour
Pakistan Journal of Biological Sciences , 2008,
Abstract: The developmental anomalies are reported in this study. The first and second abnormally are presented in right pedipalps of Paraorthochirus and Orthochirus (Buthidae) while Paraorthochirus pedipalp just includes coxa, trochanter and without other parts (femur, patella, movable and fixed finger). The right pedipalp of Orthochirus specimen has abnormally too; it has all parts of pedipalp except complete fixed finger. In both of scorpions, the left pedipalp is normal. Another case is present in venom vesicle of Hemiscourpius (Hemiscorpiidae). Pictures and morphometric measurements for three specimens are given.
Synthesis and antitubercular activity of new N,N-diaryl-4-(4,5-dichloroimidazole-2-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxamides
Amini M.,Navidpour L.,Shafiee A.
DARU : Journal of Pharmaceutical Sciences , 2008,
Abstract: Background and the purpose of the study: Dihydropyridines having carboxamides in 3 and 5 positions show anti-tuberculosis activity. The purpose of the present study was to synthesize new DHPs having possible anti-tuberculosis activity. Methods: 4,5-Dichloroimidazole-2-carboxaldehyde was condensed with N-arylaceto-acetamides and ammonium acetate in methanol to give N,N-diaryl-4-(4,5-dichloroimid-azole-2-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxamides. All compounds were screened for their antitubercular activity against Mycobacterium tuberculosis (H37Rv). Results and major conclusion: Some of the new synthesized compounds exhibited a moderate activity in comparison to rifampicin.
Scorpions of Iran (Arachnida, Scorpiones). Part VII. Kerman Province.
Navidpour, S.,Ezatkhah, M.,Kova?ík, F.,Soleglad, M. E.
Euscorpius , 2011,
Abstract: Thirteen species of scorpions belonging to two families are reported from the Kerman Province of Iran. Of these, the species Compsobuthus kaftani Kova ík, 2003, Mesobuthus macmahoni (Pocock, 1900), Orthochirus farzanpayi (Vachon et Farzanpay, 1987), Polisius persicus Fet, Capes et Sissom, 2001, Sassanidotus gracilis (Birula, 1900), and Hemiscorpius lepturus Peters, 1861 are recorded from the province for the first time. Kerman Province contains type localities of six species of scorpions, of which Kraepelinia palpator (Birula, 1903) and Orthochirus gruberi Kova ík et Fet, 2006 are valid. Prionurus crassicauda orientalis Birula, 1900 is a synonym of Androctonus crassicauda (Olivier, 1807), Buthus eupeus kirmanensis Birula, 1900 and Buthus pachysoma Birula, 1900 are probably synonyms of Mesobuthus eupeus persicus (Pocock, 1899), and Buthus gabrielis Werner, 1929, according to published information and occurrences near the type locality, probably is a synonym of Sassanidotus gracilis (Birula, 1900). These taxonomic problems are discussed below. Also, Buthus atrostriatus Pocock, 1897 is transferred to genus Compsobuthus. A key to all species of scorpions found in Kerman Province is presented.
Scorpions of Iran (Arachnida, Scorpiones). Part VI. Lorestan Province.
Navidpour, Shakhrokh,Nayebzadeh, Hassan H.,Soleglad, Michael E.,Fet, Victor
Euscorpius , 2010,
Abstract: Ten species of scorpions belonging to three families are reported from the Lorestan Province of Iran. Of these, five species are recorded from the province for the first time: Hottentotta zagrosensis Kova ík, 1997; Mesobuthus eupeus phillipsii (Pocock, 1889); Orthochirus iranus Kova ík, 2004; Razianus zarudnyi (Birula, 1903); and Scorpio maurus townsendi (Pocock, 1900). One new species is described, Hottentotta lorestanus sp. n.; it can be easily distinguished from the other four species of the genus known from Iran by its coloration; it is the only Iranian species which has the entire pedipalps yellow and the metasomal segments I to IV greenish gray. Also presented is a key to all species of scorpions found in the province.
Validation and Uncertainty Estimation of an Ecofriendly and Stability-Indicating HPLC Method for Determination of Diltiazem in Pharmaceutical Preparations
Fahimeh Sadeghi,Latifeh Navidpour,Sima Bayat,Minoo Afshar
Journal of Analytical Methods in Chemistry , 2013, DOI: 10.1155/2013/353814
Abstract: A green, simple, and stability-indicating RP-HPLC method was developed for the determination of diltiazem in topical preparations. The separation was based on a C18 analytical column using a mobile phase consisted of ethanol: phosphoric acid solution (pH = 2.5) (35?:?65, v/v). Column temperature was set at 50°C and quantitation was achieved with UV detection at 240?nm. In forced degradation studies, the drug was subjected to oxidation, hydrolysis, photolysis, and heat. The method was validated for specificity, selectivity, linearity, precision, accuracy, and robustness. The applied procedure was found to be linear in diltiazem concentration range of 0.5–50?μg/mL ( ). Precision was evaluated by replicate analysis in which % relative standard deviation (RSD) values for areas were found below 2.0. The recoveries obtained (99.25%–101.66%) ensured the accuracy of the developed method. The degradation products as well as the pharmaceutical excipients were well resolved from the pure drug. The expanded uncertainty (5.63%) of the method was also estimated from method validation data. Accordingly, the proposed validated and sustainable procedure was proved to be suitable for routine analyzing and stability studies of diltiazem in pharmaceutical preparations. 1. Introduction Anal fissure is one of the most common and painful proctologic diseases that is effectively treated and prevented with conservative measures in its acute form, whereas chronic fissures may require medical or surgical therapy. Because of the disability associated with surgery for anal fissure and the risk of incontinence, medical alternatives for surgery have been sought. Most recently, pharmacologic approaches that relax the anal smooth muscle, to accomplish reversibly what occurs in surgery, have been used to obtain fissure healing [1–3]. Glyceryl trinitrate ointment (0.2%) has an efficacy of up to 68% in healing chronic anal fissure, but it is associated with headache as the major and most common side effect. Diltiazem, a calcium channel antagonist used in the treatment of angina, hypertension, and arrhythmias, achieved healing of chronic anal fissure comparable to 0.2% Glyceryl trinitrate ointment but caused fewer side effects [4]. Therefore, it is preferred to use diltiazem to treat this chronic disease [5]. The structures of diltiazem and its main impurity are presented in Figure 1. Figure 1: Molecular structures of diltiazem (a) and desacetyl diltiazem (b). Concerning new therapeutic application of diltiazem, validated and stability-indicating methods should be available to determine
Geographical Races of Old World Screw-Worm Fly, Chrysomyia bezziana Villeneuve, 1914, in South-Western Iran
S.H. Navidpour,M. Abdi Goudarzi,A. Gholamiyan,E. Jahanifard
Journal of Biological Sciences , 2009,
Abstract: A morphological analysis was undertaken with objective of identifying markers for geographical population of Old World screw worm flies, Chrysomyia bezziana Villeneuve (Diptera: Calliphoridae) in Khoozestan province, South Western Iran. During May 2006 to August 2007 the larvae of Chrysomyia collected from infested animals (Mostly sheep) and were incubated under suitable substratum in the Entomology laboratory. Totally 986 specimens were examined and geographical races of screw-worm fly were identified based on morphological characters by using diagnosis key. The study of morphological characters of the Old World screw worm flies population of South western Iran suggested that specimens are the same with Arabian race characters and demonstrates that the outbreak of C. bezziana in Iran related to populations that originated from Arab countries of the Persian Gulf like United Arab Emirates.
Identification and Purification of the Three Toxins from Odotobuthus bidentatus, Lourenco and Pezier 2002, Venom (Scorpions, Buthidae)
B. Masihipour,A.M. Zare,S.H. Navidpour,A. Taghavi Moghadam
Journal of Biological Sciences , 2009,
Abstract: Odonthobuthus belongs to Buthidae family from which 2 species O.doriea and O. bidentatus have been collected and reported from Iran. This study investigated the venom of O. bidentatus to identify mammal toxic fractions. After collecting scorpions, they were milked with electroshock technique and then the venoms was lyophilized. The LD50 of the venom was determined by injecting the venom to 18-20 g mice via., tail vein. In order to separate different fractions, the freeze dried venom was solubilized in distilled water and centrifuged at 15000 rpm for 20 min, to separate insoluble material and the clear supernatant containing soluble venom was loaded on a chromatography column packed with sephadex G50 gel and the fractions were collected according to UV absorption at 280 nm wavelength. Second fraction was toxic in Lab animal and in order to study sub fractions, fraction II (O2) was loaded first on an anionic ion exchange resin (DEAE sephacel) out of which we obtained 2 toxic fractions (O21 and O23). Then these 2 fraction were loaded on a cationic resin (CM sephadex C25) out of which, from fraction 21, we got 2 toxic fractions (O211, O213) and from fraction O23 we got one toxic fraction (O232). SDS PAGE electrophoretic studies on these toxins showed single band appearance that indicates purified toxins with molecular weight of O211 9.2, O213 8.6 and O233 6.8 kD.
Scorpions of Iran (Arachnida, Scorpiones). Part IV. Kohgilouyeh & Boyer Ahmad Province.
Navidpour, S.,Kova?ík, F.,Soleglad, M.E.,Fet, V.
Euscorpius , 2008,
Abstract: According to previous surveys, only Mesobuthus eupeus phillipsii (Pocock, 1889), Orthochirus zagrosensis Kova ík, 2004, and Hemiscorpius lepturus Peters, 1861 have been recorded from Kohgilouyeh & Boyer Ahmad Province. Collections made by a team under Shahrokh Navidpour (Razi Reference Laboratory of Scorpion Research, Razi Vaccine and Serum Research Institute, Ahvaz, Khoozestan, Iran) reveal eight other species belonging to two families recorded from the province for the first time: Androctonus crassicauda (Olivier, 1807); Compsobuthus matthiesseni (Birula, 1905); Hottentotta saulcyi (Simon, 1880); Hottentotta zagrosensis Kova ík, 1997; Odontobuthus bidentatus Louren o et Pézier, 2002; Orthochirus iranus Kova ík, 2004; Razianus zarudnyi (Birula, 1903); and Scorpio maurus townsendi (Pocock, 1900). Also presented is a key to all species of scorpions found in the province.
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