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Raabes narrativ inszenierter Bilddiskurs als (gesellschafts-) kritischer Aufbruch Richtung Moderne?
Natalie Moser
Textpraxis : Digitales Journal für Philologie , 2010,
Abstract: Das Verh ltnis von Literatur und Gesellschaft l sst sich an Wilhelm Raabes sp tem Text Pfisters Mühle als textexterner Antrieb und als textinternes Strukturmoment aufzeigen. Die Frage nach der poetologischen Relevanz des Textes wird textintern aufgegriffen, indem die Kopplung von Frage und potentiellen Antworten durch einen narrativ inszenierten Bilddiskurs dargestellt wird. Dieser Bilddiskurs bildet die Folie für eine narrative Selbstreflexion, anhand derer sich die Zeitlosigkeit und Aktualisierbarkeit des Textes zeigt. Pfisters Mühle kann als eine Form von poetologischer Reflexion verstanden werden, da der Text erz hlend dem Erz hlen auf den Grund geht und zugleich Narration und Metanarration ist. Gleichzeitig wird auf die Unm glichkeit eines abschlie enden Metadiskurses verwiesen.
Vitamin B12 Activates the Wnt-Pathway in Human Hair Follicle Cells by Induction of beta-Catenin and Inhibition of Glycogensynthase Kinase-3 Transcription  [PDF]
Walter Krugluger, Karl Stiefsohn, Katharina Laciak, Karl Moser, Claudia Moser
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2011, DOI: 10.4236/jcdsa.2011.12004
Abstract: Background and Objectives: Micrograft transplantation is accompanied by a transient induction of telogen in transplanted hair follicles (HF), which might be avoided by supporting the metabolic pathways of the micrograft during the ex vivo period. Vitamin B12 (cobalamin) has been suggested to influence HF growth and cycling in humans, but the mechanisms are unclear. Method: HFs were obtained from patients undergoing routine micrograft transplantation and were cultured for 5 days in Dulbecco’s modified Eagles Medium, supplemented with different amounts of vitamin B12. Hair shaft elongation (HSE) of the isolated HFs as well as quantitative changes of mRNA for beta-catenin, glykogensynthase kinase-3 (GSK-3) and TCF/Lef-1 in HF cells were determined. Results: In vitro HSE demonstrated a dose dependent induction of HSE after stimulation with 2.5 ug/ml and 25 ug/ml vitamin B12 (6.2 +/- 2.1% and 15.4 +/- 3.8% respectively). A dose dependent induction of beta-catenin-mRNA could be demonstrated in cultured HFs after stimulation with 2.5 ug/ml and 25 ug/ml vitamin B12 (fold change compared to DMEM: 9.5 +/- 2.7, p < 0.05 and 23.1 +/- 7.4, p < 0.01; respectively). Concomitantly the amounts of GSK-3 were significantly reduced after stimulation with 25 ug/ml vitamin B12 (fold change compared to DMEM: 0.76 +/- 0.12, p < 0.05). Conclusions: Our data demonstrate a hair growth promoting effect of vitamin B12 in vitro. This effect is accompanied by the modulation of intracellular signal transduction molecules of the wnt-pathway and might promote hair growth after micrograft transplantation.
Response to: cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection
Carsten Moser
Arthritis Research & Therapy , 2010, DOI: 10.1186/ar3146
Abstract: The method of producing ACS has been carefully optimized to enrich for anti-inflammatory cytokines, such as interleukin (IL)-1Ra, IL-10, and IL-13, while keeping low the concentration of inflammatory cytokines, such as IL-1β and tumor necrosis factor-alpha (TNF-α). The ACS preparation of Rutgers and colleagues had increased concentrations of IL-1β and TNF-α, and this raises questions about the composition of the product that was tested.Nevertheless, despite the elevated concentrations of these two cytokines, there was no adverse effect of ACS on proteoglycan turnover in the cartilage explant cultures. This suggests that anti-inflammatory and possibly chondroprotective ingredients within ACS predominate. Further studies using additional controls and autologous instead of heterologous serum would be interesting.The third component of the study by Rutgers and colleagues measured cytokine levels in synovial fluids before and after treatment with ACS. No changes were found, but it should be noted that Orthokine should be used only when knee effusion has been removed effectively. The described possible aspiration of synovial fluid after treatment with ACS raises questions about the selection of these patients or the composition of the injected ACS. In this regard, it is worth noting that another study [2,3] involving the injection of Orthokine ACS into knees after ACL plasty showed evidence of reduced IL-1β content in synovial fluid. This reduction corresponded with improved pain and function and with reduced tunnel widening. Clearly, the mechanisms through which ACS brings about clinical improvement are incompletely understood and should be the subject of additional research.ACL: anterior cruciate ligament; ACS: autologous conditioned serum; IL: interleukin; TNF-α: tumor necrosis factor-alpha.The author declares that they have no competing interests.
Psicologia Ambiental e estudos pessoas-ambiente: que tipo de colabora??o multidisciplinar?
Moser, Gabriel;
Psicologia USP , 2005, DOI: 10.1590/S0103-65642005000100015
Abstract: this article aims to show the existing collaborations between environmental psychology and the diverse people-environment studies, based on the works presented in the congress iaps-16 (paris, 2000). in the relation between transdisciplinarity, pluridisciplinarity and interdisciplinarity, it understands that scientific functioning is necessarily mono-disciplinary, while intervention in people-environment relations involves a complex dynamics. as for intervention (socio-environmental handling), it distinguishes two types of functioning: interdisciplinary and transdisciplinary. it concludes that only the knowledge that integrates the several disciplinary approaches into transdisciplinary approaches will provide an adequate answer to the challenges of this new century.
A Psicologia Ambiental: competência e contornos de uma disciplina. Comentários a partir das contribui??es
Moser, Gabriel;
Psicologia USP , 2005, DOI: 10.1590/S0103-65642005000100030
Abstract: this text presents a reflective and critical synthesis of the themes of the symposium psychology and environment, as developed by the successive participants. it approaches, initially, the issue of the unity of environmental psychology, focusing on its object, role and utility. next, it discusses environmental psychology between disciplinary affirmation and pluridisciplinary errancy. focusing on the theme environmental psychology and public policies, it proposes benchmarks for efficient political visibility. finally, it concludes by presenting a program for the future.
A nova gera??o de políticas sociais no contexto europeu: workfare e medidas de ativa??o
Moser, Liliane;
Revista Katálysis , 2011, DOI: 10.1590/S1414-49802011000100008
Abstract: this article analyzes the configuration - in the nation sates that constitute the european union - of a new generation of social policies governed by the logic of activation, aimed predominately at the insertion of people in the labor market. it reviews articles by european authors who analyze the transformations that have occurred in social protection systems in these countries. it found that this logic combines a series of characteristics that support programs, projects and actions marked by their disciplinary and punitive content and which require recipients to offer counterparts for the benefits received.
Engineering for problem solving in future: Eco-social market economy and eco-social tech
环境科学学报(英文版) , 2001,
Abstract: IntroductionTechnologyisplayingapowerfulroleatpresent,evenpeoplethinkthatproblemscanbesolvedmainlywithtechnology .Indeed,admirableprogresswasmade ,however,atthesametime ,alsotheproblemsshowanexponentialgrowth .Fig.1illustratestheshapeofgrowthofnearlyallthi…
Ultra-high-field magnetic resonance: Why and when?
Ewald Moser
World Journal of Radiology , 2010,
Abstract: This paper briefly summarizes the development of magnetic resonance imaging and spectroscopy in medicine. Aspects of magnetic resonancephysics and -technology relevant at ultra-high magnetic fields as well as current limitations are highlighted. Based on the first promising studies, potential clinical applications at 7 Tesla are suggested. Other aims are to stimulate awareness of the potential of ultra-high field magnetic resonance and to stimulate active participation in much needed basic or clinical research at 7 Tesla or higher.
Vroegmoderne Nederlandse manuscriptcultuur in diachroon en internationaal perspectief: van blinde vlek tot multifocale glazen
Moser, Nelleke
Neerlandistiek.nl , 2007,
An epsilon-regularity result for generalized harmonic maps into spheres
Roger Moser
Electronic Journal of Differential Equations , 2003,
Abstract: For $m,n ge 2$ and $1 < p < 2$, we prove that a map $u in W_mathrm{loc}^{1,p}(Omega,mathbb{S}^{n - 1})$ from an open domain $Omega subset mathbb{R}^m$ into the unit $(n - 1)$-sphere, which solves a generalized version of the harmonic map equation, is smooth, provided that $2 - p$ and $[u]_{mathrm{BMO}(Omega)}$ are both sufficiently small. This extends a result of Almeida [1]. The proof is based on an inverse Holder inequality technique.
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