Many applications do not fit well with the traditional best effort packet delivery policy of the Internet. These include applications such as Internet telephony and video conferencing which require voice and bulky graphical images transfer. Therefore, the policies of assigning traffic to various service classes and providing service as per the service level agreement of the user with the network provider came into existence. Multi-protocol Label Switching is the backbone of fast switching technology that helps the network service providers to implement these policies. It provides Quality of service oriented reserved paths from the source to the destination for the user’s traffic. Selection of these paths is a cumbersome task, especially when the traffic forecast is totally unknown. Furthermore, nodes and link failures in the Internet worsen the situation. This paper addresses the issue of selecting Label Switched Paths (LSPs) for various traffic demands in the network so that the resultant network has the

“Indigenous vaccine” developed from native “Indian Bison Type” strain (“S5”) of Mycobacterium avium subspecies paratuberculosis (MAP) of “goat origin” was first time evaluated in a sheep flock of Bharat Merino breed located in Mannavanur town of Tamil Nadu in South India. Therapeutic efficacy of the vaccine was evaluated for 3 years between 2008 and 2010, on the basis of improvements in productivity (body weights, reproductive efficiency and survivability), physical condition, clinical symptoms (weakness, diarrhea, wool quality), immune response (sero-conversion) and infection load in feces (shedding). After immunization of the flock in 2008, the successive progenies of 112 and 53 lambs born in 2009 and 2010, respectively were vaccinated. Whereas, 40 lambs born to control animals were kept as unvaccinated controls. Though gain in body weights in vaccinated versus controls were not significant in 2008, growth rates were distinctly superior in I^st and II^nd generations of vaccinated lambs. Reproductive performance (tupping percent) and survivability of lambs and adult sheep improved significantly. There was overall reduction in yearly morbidity (diarrhea) and mortality rates of the flock in post vaccination years. Shedding of MAP in feces was reduced in vaccinated sheep by 6.2%, 14.3% and 27.3% in 2008, 2009 and 2010 respectively, whereas shedding increased in the control sheep. Seromonitoring of the animals by “indigenous ELISA kit” showed enhanced “flock immunity” in successive generations. “Indigenous vaccine” reduced clinical disease and shedding and improved immunity and productivity of Bharat Merino flock, endemic for Johne’s disease.