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Search Results: 1 - 10 of 210969 matches for " Nancy L. Brackett "
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Infertility in Men with Spinal Cord Injury: Research and Treatment
Nancy L. Brackett
Scientifica , 2012, DOI: 10.6064/2012/578257
Infertility in Men with Spinal Cord Injury: Research and Treatment
Nancy L. Brackett
Scientifica , 2012, DOI: 10.6064/2012/578257
Abstract: Spinal cord injury (SCI) occurs most often to young men. Following SCI, most men are infertile due to a combination of erectile dysfunction, ejaculatory dysfunction and semen abnormalities. Erectile dysfunction may be treated by the same therapies that are used in the general population. Similarly, the same treatments that are effective to assist conception in couples with non-SCI male factor patients are effective in assisting conception in SCI male-factor patients. The most apparent differences in male-factor symptoms between SCI and non-SCI patients are the high occurrences of anejaculation and atypical semen profiles in men with SCI. Methods available to assist ejaculation in men with SCI include penile vibratory stimulation and EEJ. Use of surgical sperm retrieval as the first line of treatment for anejaculation in men with SCI is controversial. Most men with SCI have a unique semen profile characterized by normal sperm concentration, but abnormally low sperm motility. Toxic substances in the semen contribute to this problem. Despite impaired sperm parameters, pregnancy outcomes using sperm from men with SCI are similar to pregnancy outcomes using sperm from non-SCI men. Future studies should focus on improving natural ejaculation and improving semen quality in these men. 1. Introduction Spinal cord injury occurs most often to young men at the peak of their reproductive health [1]. In the United States, 80% of new injuries occur to men between the ages of 16 and 45 [2]. Similar statistics are found worldwide [3–12]. Owing to the fact that the most common causes of injury include motor vehicle accidents, violence, sport-related injuries, and falls, it has been assumed that the gender disparity is due to more men than women engaging risk-taking behavior that leads to injury. The actual reason for the disparity is unknown. There is some evidence suggesting that hormones, rather than behavior, may contribute to the disparity. For example, it has been shown that estrogen may be neuroprotective and/or that testosterone may be neurotoxic after injury [13, 14]. Following SCI, most men have severely impaired fertility characterized by erectile dysfunction (ED), ejaculatory dysfunction, and semen abnormalities [15–18]. This paper will discuss current treatments for infertility in men with SCI, including treatments for ED as well as methods of semen retrieval. A discussion of the latest research findings regarding causes of abnormal semen quality will also be presented. The paper will conclude with recommendations for treating infertile couples with a male
The Perspicuity of the Scriptures: Presupposition, Principle or Phantasm
Kristian Brackett
Kairos : Evangelical Journal of Theology , 2010,
Abstract: The doctrine of the perspicuity of the Scriptures was clearly articulated and strongly defended by the Reformers. Evangelical Christians today also need to reaffirm and defend this biblical doctrine. This article addresses the importance of this doctrine and looks at different definitions of this doctrine as well as its limitations. In the second part, theological and biblical evidence supporting the perspicuity of the Scriptures is presented. In the final section, the author suggests an answer to the question of whether the perspicuity of the Scriptures is a presupposition brought to the biblical text or a principle of interpretation.
Inspiring Student Self-Motivation
Virginia Brackett
InSight : A Journal of Scholarly Teaching , 2007,
Abstract: While normally appreciative of the invitation to join colleagues in a discussion of pedagogy and what “works” in the classroom, I have in most instances reluctantly participated in discussion of student motivation. I dip my toe into this philosophical quagmire only if permitted license to substitute the phrase student inspiration in place of student motivation. I also find it helpful to turn the rhetorical tables, as it were, and consider self-motivation on the part of students. The concept of individuals who hold some sense of self that a classroom mentor may nurture through student inspiration is one in which I place a modicum of trust. To “inspire” is literally to “breathe in,” to actively pull sustenance from a proffered external source. Active student determination based on some sense of self may couple with instructor inspiration to promote academic success.
Zorn: Avant/Après/Passé
John Lowell Brackett
Avant : Journal of Philosophical-Interdisciplinary Vanguard , 2012,
Abstract: Witold Wachowski’s brief exchange with John Zorn provides us with many valuable insights relating to the composer’s aesthetic. Zorn’s professed antipathy towards audiences, his faith in the creative instinct of the “artist,” and his belief in the transcendental nature of musical works (as a gateway into a world of “truth” and “beauty”) are all refrains commonly encountered in many interviews with the composer. Given the fact that Zorn emphasizes these themes in his very short interview with Wachowski, we can assume that these ideas form the core of Zorn’s musical and artistic aesthetic. For any person with even a basic knowledge of Western aesthetic traditions, however, these same aesthetic features and positions characterize musical institutions common to the Western art tradition, particularly the “romantic” ideal of music and composers that developed in the nineteenth century. Philosophers (most notably Hegel and Kant) along with music critics and composers (such as Friedrich Schiller, E.T.A. Hoffmann, Friedrich Schlegel, Robert Schumann, and Eduard Hanslick) all contributed to the development of a romantic musical aesthetic in the nineteenth century that emphasized the role of the artist (as a “genius” or “god-like”) who created “works” that – through purely musical relations that exist irregardless of the listener’s abilities – reveal hidden worlds of truth and beauty, worlds far-removed from the humdrum concerns of daily existence. Given the close (nearly one-to-one) correspondences between Zorn and aestheticians/philosophers of the nineteenth century, one could make the argument that Zorn holds a “romantic” view of music and art.
Zorn: Avant/Après/Passé [przek ad]
John Lowell Brackett
Avant : Journal of Philosophical-Interdisciplinary Vanguard , 2012,
Abstract: Krótki wywiad Witolda Wachowskiego z Johnem Zornem zawiera wiele cennych spostrze eń zwi zanych z estetyk tego kompozytora. Rzekoma niech Zorna do publiczno ci, jego wiara w kreatywny instynkt artysty” oraz jego przekonanie o transcendentalnej naturze dzie muzycznych (które s bram do wiata prawdy” i pi kna”) niczym refren powtarzaj si w wielu wywiadach z muzykiem. Zorn w krótkim wywiadzie z Wachowskim podkre la w a nie te przekonania, dlatego mo emy przyj , e stanowi one fundament jego muzycznej i artystycznej estetyki. Dla ka dego, kto posiad cho by podstawow wiedz o zachodniej tradycji estetycznej, jest jasne, e te same cechy i stanowiska estetyczne charakteryzuj muzyczne instytucje wspólne dla zachodniej tradycji artystycznej, a w szczególno ci romantyczny” idea muzyki i kompozytora rozwini ty w XIX wieku. Filozofowie (g ównie Hegel i Kant) razem z krytykami muzycznymi i kompozytorami (Schiller, Hoffmann, Schlegel, Schuman, Hanslick) przyczynili si do stworzenia romantycznej estetyki muzycznej w XIX wieku, akcentuj cej rol artysty ( geniusza” lub boga”), który tworzy dzie a” ods aniaj ce – poprzez czysto muzyczne zwi zki istniej ce niezale nie od wra liwo ci s uchacza – ukryte wiaty prawdy i pi kna, wiaty odleg e od trosk ycia codziennego. Zwa ywszy na bliskie zwi zki Zorna z estetykami/filozofami XIX-wiecznymi, mo na powiedzie , e wyznaje on romantyczny” pogl d na muzyk i sztuk .
Benefits of Docosahexaenoic Acid, Folic Acid, Vitamin D and Iodine on Foetal and Infant Brain Development and Function Following Maternal Supplementation during Pregnancy and Lactation
Nancy L. Morse
Nutrients , 2012, DOI: 10.3390/nu4070799
Abstract: Scientific literature is increasingly reporting on dietary deficiencies in many populations of some nutrients critical for foetal and infant brain development and function. Purpose: To highlight the potential benefits of maternal supplementation with docosahexaenoic acid (DHA) and other important complimentary nutrients, including vitamin D, folic acid and iodine during pregnancy and/or breast feeding for foetal and/or infant brain development and/or function. Methods: English language systematic reviews, meta-analyses, randomised controlled trials, cohort studies, cross-sectional and case-control studies were obtained through searches on MEDLINE and the Cochrane Register of Controlled Trials from January 2000 through to February 2012 and reference lists of retrieved articles. Reports were selected if they included benefits and harms of maternal supplementation of DHA, vitamin D, folic acid or iodine supplementation during pregnancy and/or lactation. Results: Maternal DHA intake during pregnancy and/or lactation can prolong high risk pregnancies, increase birth weight, head circumference and birth length, and can enhance visual acuity, hand and eye co-ordination, attention, problem solving and information processing. Vitamin D helps maintain pregnancy and promotes normal skeletal and brain development. Folic acid is necessary for normal foetal spine, brain and skull development. Iodine is essential for thyroid hormone production necessary for normal brain and nervous system development during gestation that impacts childhood function. Conclusion: Maternal supplementation within recommended safe intakes in populations with dietary deficiencies may prevent many brain and central nervous system malfunctions and even enhance brain development and function in their offspring.
Concept mapping for learners of all ages
Nancy L. Gallenstein
Journal for Educators, Teachers and Trainers , 2013,
Abstract: Concept mapping is an inquiry technique that provides students at all ages with opportunities to demonstrate learning through performance. A concept map refers to a graphic/visual representation of concepts with linking connections that show various relationships between concepts (Novak & Gowin, 1984). Assessment is an ongoing process integrated with instruction across subject areas. The National Council of Teachers of Mathematics (NCTM) emphasizes that assessment should focus on both the enhancement of student learning as well as serve as a valuable tool for making instructional decisions (NCTM, 2000). Assessment activities can take on a variety of forms, one being performance tasks. In this manuscript, an explanation of concept mapping is provided for learners ages 3 – 12 along with several examples of concept maps for young learners, including examples from an assessment project in the subject area of mathematics. Also presented are the numerous benefits of the concept mapping technique for both students and teachers.
Phantom study of the impact of adaptive statistical iterative reconstruction (ASiRTM) on image quality for paediatric computed tomography  [PDF]
Angjelina Protik, Karen Thomas, Paul Babyn, Nancy L. Ford
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.512A100

Quantitative analysis of image quality will be helpful for designing ASiRTM-enhanced paediatric CT protocols, balancing image quality and radiation dose. Catphan600 phantom studies were performed on a GE Discovery HD750 64-slice CT scanner. Images were reconstructed with 0% - 100% ASiRTM (tube current 150 mA, variable kVp 80 - 140) in order to determine the optimal ASiRTM-Filtered Back Projection (FBP) blend. Images reconstructed with a 50% ASiRTM-50% FBP blend were compared to FBP images (0% ASiRTM) over a wide range of kVp (80 - 140) and mA (10 - 400) values. Measurements of image noise, CT number accuracy and uniformity, spatial and contrast resolution, and low contrast detectability were performed on axial and reformatted coronal images. Improvements in CNR, low contrast detectability and radial uniformity were observed in ASiRTM images compared to FBP images. 50% ASiRTM was associated with a 26% - 30% reduction in image noise. Changes in noise texture were observed at higher %

Monitoring vascular changes induced by photodynamic therapy using contrast-enhanced micro-computed tomography  [PDF]
Otilia C. Nasui, Stuart K. Bisland, Nancy L. Ford
Journal of Biomedical Science and Engineering (JBiSE) , 2013, DOI: 10.4236/jbise.2013.62016

The aim of this study was to determine whether contrast-enhanced micro-computed tomography can be used for non-invasive imaging of the early-stage changes in the vasculature of tumours that have been treated with photodynamic therapy (PDT). The subjects used were C3H mice with an RIF-1 tumour implanted subcutaneously and allowed to grow for 3 weeks prior to treatment. The experimental groups were PDT-treated (150 J/cm2 and 50 J/cm2) and control (150 J/cm2 light-only and untreated). The laser light exposure was performed at 15 - 30 minutes after the administration of the photosensitizer (BPD-MA). The contrast-enhanced micro-computed tomography imaging procedure consisted of eight-second scans taking place before treatment and up to 24 hours after treatment. The 150 J/cm2 PDT group showed a significant increase in the ratio of blood volume to tumour volume at 2, 8 and 24 hours after treatment when compared to pre-treatment measurements (p < 0.01). The observed increase in the blood volume to tumour volume at the later time points corresponds to a decrease in epithelial coverage on immunohistochemical stained (CD31) slides for the 150 J/cm2 PDT group at 24 hours after treatment. This preliminary study indicates that micro-CT can detect compromised vasculature in tumours treated with high-fluence photodynamic therapy as early as 2 hours post treatment.

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