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that inflammatory substances play an important role in the carcinogenesis
process. In the process, cytokines and growth factor secreted by cells can
actively recruit immune cells in the carcinogenesis microenvironment, further, promote
carcinogenesis progression. The carcinogenesis microenvironment even subverted
the immune system, moreover, enhanced the carcinogenesis through immune suppressive
mechanisms within the carcinogenesis microenvironment.