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Search Results: 1 - 10 of 5918 matches for " Nadine; Reyes "
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Mecanismos de evasión y persistencia de Mycobacterium tuberculosis durante el estado de latencia y posibles estrategias para el control de la infección latente
Nadine álvarez,Reinier Borrero,Fátima Reyes,Frank Camacho
Vaccimonitor , 2009,
Abstract: Mycobacterium tuberculosis, el agente causal de la tuberculosis, infecta aproximadamente alrededor de 54 millones de personas en todo el mundo cada a o y constituye una de las principales causas de muerte entre las enfermedades infecciosas. La mayoría de los individuos infectados con M. tuberculosis desarrollan una infecciónlatente, etapa en la que este microorganismo sobrevive dentro del hospedero, evadiendo los mecanismos de defensa del sistema inmune del portador. La terapia actual de la tuberculosis comprende la administración de cuatro antimicrobianos durante seis meses. No obstante, M. tuberculosis es capaz de sobrevivir después devarios meses de tratamiento con esa terapéutica antimicrobiana combinada. Existen evidencias de que el bacilo tuberculoso, durante la fase estacionaria de crecimiento, incrementa su tolerancia a los ambientes de estrés. El costo de los fármacos empleados para el tratamiento y el incremento de cepas de M. tuberculosismultidrogorresistentes constituyen uno de los motivos principales para desarrollar una nueva vacuna contra la tuberculosis. Sin embargo, su erradicación está afectada por la capacidad que posee el bacilo tuberculoso de sobrevivir en estado de latencia durante décadas, en las condiciones de hipoxia y causar infecciones recurrentes.
Mycobacterium tuberculosis: factores de virulencia
Borrero,Reinier; álvarez,Nadine; Reyes,Fátima; Sarmiento,María Elena; Acosta,Armando;
Vaccimonitor , 2011,
Abstract: mycobacterium tuberculosis is the causative agent of tuberculosis, one of the most lethal diseases worldwide. bcg is the only available vaccine for tuberculosis control, but at the same time it fails in the protection from pulmonary tuberculosis, which is the most common and responsible form of dissemination. the identification of virulence factors of the causative organism could help in developing a new vaccine candidate capable of neutralizing the action of these pathogenic determinants. the use of different animal models has allowed to reproduce the stages of the disease and to measure or to quantify the virulence of different circulating strains of m. tuberculosis. gene mutations and other molecular biology techniques have made possible to elucidate the specific genes involved in virulence of this organism, that encodes many complex and different factors.
Mycobacterium tuberculosis:factores de virulencia.
Reinier Borrero,Nadine álvarez,Fátima Reyes,María Elena Sarmiento
Vaccimonitor , 2011,
Abstract: Mycobacterium tuberculosis es el agente causal de la tuberculosis, una de las enfermedades infecciosas más letales en el mundo. La única vacuna disponible para su control es el BCG, sin embargo, falla en la protección contra la tuberculosis pulmonar, siendo esta la forma más frecuente y responsable de la diseminación. Laidentificación de factores de virulencia del microorganismo causal pudiera ayudar en el desarrollo de un nuevo candidato vacunal que sea capaz de neutralizar la acción de esos determinantes patogénicos.El empleo de diferentes modelos animales ha permitido reproducir las etapas de la enfermedad, así como medir o cuantificar la virulencia de las distintas cepas circulantes de Mycobacterium tuberculosis. Las mutaciones génicas y otras técnicas de biología molecular han posibilitado dilucidar los genes específicos involucrados en la virulencia de este microorganismo que codifican para múltiples y complejos factores de diferente naturaleza.
Studying Heavy Metals in Sediments Layers along Selected Sites on the Lebanese Coast  [PDF]
Journal of Water Resource and Protection (JWARP) , 2010, DOI: 10.4236/jwarp.2010.21006
Abstract: Ensuring the environmental protection of the Lebanese coast requires a continues monitoring system. For this purpose, four heavy metals (Fe, Mn, Cu and Pb in the marine sediments along the Lebanese coast were selected for analysis Sampling was carried out from two sites: Beirut and Batroun. Thus, 1g of dried sample is used for digestion by wet mineralization in order to determine the concentration of the four heavy metals by atomic absorption spectrometry. The results showed that Beirut area is polluted, by Fe and Mn as well as the station Bat 2 of Batroun. For Cu and Pb, Batroun region is more polluted in the superficial layers. The analysis also showed significant difference between the sites except for Cu. A difference between depths and between particles size fractions are observed for all the parameters studied. There is no a significant difference in layer sequence except for the Pb, and neither between the repetitions of the same sample. Results showed that the values of the four metals studied do not exceed the maximum limits at both sites, but they showed increase in comparison with the analyses obtained before July 2006 conflict, which was caused by the release of large quantity of fuel-oil from Jiyeh Power Station.
Influence of production processes in quality of fermented milk "Laban" in Lebanon  [PDF]
Zeineddine Mayssoun, Nassif Nadine
Health (Health) , 2010, DOI: 10.4236/health.2010.24057
Abstract: Yoghurt (Laban) is one of the most consumed food products in Lebanon. Thus its quality has given a concern. In this study, the sensory, chemical and rheological properties of commercial and traditional samples were investigated in order to characterize this fermented milk. Hence, Laban samples were collected from 14 areas in Lebanon; especially from mountainous regions and from the capital Beirut. Forty-two samples were provided by processing industry whether at small, medium, or large scale. A statistical analysis was carried out, and thus sensory and physicochemical properties were subjected to two approaches of variance analysis. Pearson correlation coefficients between attributes were also calculated. Both, the analyses of variance and correlations were conducted using SPSS 3. The physicochemical analysis and the microbiological analysis exhibit a significant effect of the date, and the manufacturing process. Also, the instrumental data showed no significant correlation between physicochemical and microbiological parameters, which indicates that they are completely independent. Moreover, the general appreciation of descriptive sensory analysis of products display that this appreciation is not dependant on the production process. It is also noticed that some sensory characteristics can be dread by instrumental measures. This research endorses the essential role of quality control for the manufacturing of yoghurt in Lebanon.
Preoccupation with Weight and Eating Patterns of Lebanese and Cypriot Female Students  [PDF]
Ioanna Katsounari, Nadine Zeeni
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.36073
Abstract: This comparative cross-cultural study explores the prevalence of preoccupation with weight and eating patterns among female university students in two distinct cultural contexts, Cyprus and Lebanon. Data was collected by means of self-administered questionnaires to 200 students from each culture. To gather the data for this study, the Dutch Eating Behavior Scale was used for the assessment of eating behaviors. Body Mass Index (BMI) and Weight directed behavior were also calculated. The Pearson Product-Moment Correlation Coefficient was used to determine whether there is a linear relationship between students’ BMI and eating behaviors. Findings suggested that with respect to culture and pre-occupation with weight, Cypriot students are more pre-occupied with their weight. However, Lebanese students received higher emotional and external eating scores. In addition, a positive relationship between Body Mass Index, restrained and emotional eating was found in both cultures Also, in both cultures there was a significant positive relationship between restrained and emotional eating, emotional and external eating. These findings suggest that in the Lebanese culture, eating dysfunction among women may be due to responsiveness to external and emotional cues while in the Cypriot culture may be due to an over pre-occupation with weight fuelled by sociocultural agents. Understanding the underlying causes of eating deviations and the existing elements in each culture which promote these deviations could lead to better prevention efforts in two societies where the rise in eating disturbances has been alarming.
“We Are Only as Strong as We Are United, as Weak as We Are Divided” a Dynamic Analysis of the Peer Support Networks in the Harry Potter Books  [PDF]
Goele Bossaert, Nadine Meidert
Open Journal of Applied Sciences (OJAppS) , 2013, DOI: 10.4236/ojapps.2013.32024

This research studied the concept of enacted peer support during adolescence by means of the Harry Potter Series. A network approach was used. Results indicated the importance of reciprocity and transitivity for enacted peer support during adolescence. Contrary to our expectations, gender, age and personality traits did not affect enacted peer support. No homophily effects based on gender and age were detected. However, students were found to be more supportive of students with similar personality traits. We hope this study adds to the current knowledge on peer support in adolescence and promotes the use of social theories and methods in literacy research.

Mecanismos de evasión y persistencia de Mycobacterium tuberculosis durante el estado de latencia y posibles estrategias para el control de la infección latente
álvarez,Nadine; Borrero,Reinier; Reyes,Fátima; Camacho,Frank; Mohd,Norazmi; Sarmiento,María Elena; Acosta,Armando;
Vaccimonitor , 2009,
Abstract: mycobacterium tuberculosis, the causative agent of tuberculosis, infects approximately 54 million people around the world each year and is a leading cause of death among infectious diseases. most individuals infected with m. tuberculosis develop a latent infection stage at which this organism survives within the host, evading the defense mechanisms of the host immune system. current tb therapy involves administration of four antibiotics for six months. however, m. tuberculosis is able to survive after several months of treatment with this antimicrobial combination therapy. there is evidence that the tb bacilli during the stationary phase of growth, increases tolerance to stress environments. the cost of drugs used for treatment and the increase of m. tuberculosis multidrug resistant strains, is one of the main reasons for developing a new vaccine against tuberculosis. however, the elimination of the disease has been prevented by the ability of the bacillus to both survive in latency for decades, under conditions of hypoxia and to cause recurrent infections.
Surgical Treatment of Atrial Fibrillation: A Review
Nadine Hiari
Cardiology Research and Practice , 2011, DOI: 10.4061/2011/214940
Abstract: Atrial fibrillation is the most commonly sustained arrhythmia in man. While it affects millions of patients worldwide, its incidence will markedly increase with an aging population. Primary goals of AF therapy are to (1) reduce embolic complications, particularly stroke, (2) alleviate symptoms, and (3) prevent long-term heart remodelling. These have been proven to be a challenge as there are major limitations in our knowledge of the pathological and electrophysiological mechanisms underlying AF. Although advances continue to be made in the medical management of this condition, pharmacotherapy is often unsuccessful. Because of the high recurrence rate of AF despite antiarrhythmic drug therapy for maintenance of sinus rhythm and the adverse effects of these drugs, there has been growing interest in nonpharmacological strategies. Surgery for treatment of AF has been around for some time. The Cox-Maze procedure is the gold standard for the surgical treatment of atrial fibrillation and has more than 90% success in eliminating atrial fibrillation. Although the cut and sew maze is very effective, it has been superseded by newer operations that rely on alternate energy sources to create lines of conduction block. In addition, the evolution of improved ablation technology and instrumentation has facilitated the development of minimally invasive approaches. In this paper, the rationale for surgical ablation for atrial fibrillation and the different surgical techniques that were developed will be explored. In addition, it will detail the new approaches to surgical ablation of atrial fibrillation that employ alternate energy sources. 1. Introduction Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. The overall prevalence of AF in the population ranges between 1 and 2%. The relationship between AF and age is strong. The prevalence doubles with each decade of age, reaching almost 9% at the age of 80–89 years [1, 2]. This can be an underestimate of the real number as it overlooks the undetected asymptomatic AF cases and paroxysmal AF. Although atrial fibrillation can be considered an innocuous arrhythmia, it is associated with serious morbidity and mortality [3]. First, it increases the risk of thromboembolism and stroke, as a result of blood stasis in the left atrium. It has been estimated that AF results in three- to five-fold increase in stroke risk [4]. Second, the irregularly irregular heart beat leads to symptoms palpitations, shortness of breath, anxiety, and reduced exercise tolerance in the patient. Third, atrial
Late Byzantine Mineral Soda High Alumina Glasses from Asia Minor: A New Primary Glass Production Group
Nadine Schibille
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0018970
Abstract: The chemical characterisation of archaeological glass allows the discrimination between different glass groups and the identification of raw materials and technological traditions of their production. Several lines of evidence point towards the large-scale production of first millennium CE glass in a limited number of glass making factories from a mixture of Egyptian mineral soda and a locally available silica source. Fundamental changes in the manufacturing processes occurred from the eight/ninth century CE onwards, when Egyptian mineral soda was gradually replaced by soda-rich plant ash in Egypt as well as the Islamic Middle East. In order to elucidate the supply and consumption of glass during this transitional period, 31 glass samples from the assemblage found at Pergamon (Turkey) that date to the fourth to fourteenth centuries CE were analysed by electron microprobe analysis (EPMA) and by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). The statistical evaluation of the data revealed that the Byzantine glasses from Pergamon represent at least three different glass production technologies, one of which had not previously been recognised in the glass making traditions of the Mediterranean. While the chemical characteristics of the late antique and early medieval fragments confirm the current model of glass production and distribution at the time, the elemental make-up of the majority of the eighth- to fourteenth-century glasses from Pergamon indicate the existence of a late Byzantine glass type that is characterised by high alumina levels. Judging from the trace element patterns and elevated boron and lithium concentrations, these glasses were produced with a mineral soda different to the Egyptian natron from the Wadi Natrun, suggesting a possible regional Byzantine primary glass production in Asia Minor.
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