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Search Results: 1 - 10 of 466561 matches for " N.T.R. Meda "
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In vitro Antioxidant, Xanthine Oxidase and Acetylcholinesterase Inhibitory Activities of Balanites aegyptiaca (L.) Del. (Balanitaceae)
N.T.R. Meda,A. Lamien-Meda,M. Kiendrebeogo,C.E. Lamien
Pakistan Journal of Biological Sciences , 2010,
Abstract: The present study aimed to test the validity of Balanites aegyptiaca remedies used for the treatment of rheumatisms and mental disorders by examining the antioxidant, xanthine oxidase and acetylcholinesterase inhibitory activities of galls and leaves extracts and fractions. The total phenolics and flavonoids were measured using Folin-Ciocalteu and AlCl3 reagents, respectively. Two methods i.e., FRAP and ABTS were used to estimate the total antioxidant capacity of the plant materials. The FRAP and ABTS antioxidant activities showed that among all extracts and fractions tested, the best antioxidant activities were found with the galls dichloromethane and the leaves ethyl acetate fractions. The antioxidant activities did correlated significantly with the total phenolic and flavonoid contents. The study also showed that B. aegyptiaca galls and leaves fractions exhibited a moderate xanthine oxidase inhibitory activity comparatively to the acetylcholinesterase which was weakly inhibited by the tested extracts and fractions.
In vitro Antioxidant, Lipoxygenase and Xanthine Oxidase Inhibitory Activities of Fractions from Cienfuegosia digitata Cav., Sida alba L. and Sida acuta Burn f. (Malvaceae)
K. Konate,A. Souza,A.Y. Coulibaly,N.T.R. Meda
Pakistan Journal of Biological Sciences , 2010,
Abstract: In this study polyphenol content, antioxidant activity, lipoxygenase (LOX) and Xanthine Oxidase (XO) inhibitory effects of n-hexane, dichloromethane, ethyl acetate and n-butanol fractions of aqueous acetone extracts from S. alba L., S. acuta Burn f. and Cienfuegosia digitata Cav. were investigated. The total phenolics, flavonoids, flavonols and total tannins were determined by spectrophotometric methods using Folin-ciocalteu, AlCl3 reagents and tannic acid, respectively. The antioxidant potential was evaluated using three methods: inhibition of free radical 2,2-diphenyl-1-picrylhydramzyl (DPPH), ABTS radical cation decolorization assay and Iron (III) to iron (II) reduction activity (FRAP). For enzymatic activity, lipoxygenase and xanthine oxidase inhibitory activities were used. This study shows a relationship between polyphenol contents, antioxidant and enzymatic activities. Present results showed that ethyl acetate and dichloromethane fractions elicit the highest polyphenol content, antioxidant and enzymatic activities.
Antioxidant and Antibacterial Activities of Five Verbenaceae Species from Burkina Faso
M.J. Bangou,N.T.R. Méda,A.M.E. Thiombiano,M. Kiendrebéogo
Current Research Journal of Biological Sciences , 2012,
Abstract: The present study aimed to evaluate the antioxidant and the antibacterial activities of methanol extracts from five species from Verbenaceae family and to quantify their polyphenols. Two methods i.e., FRAP and DPPH were used to estimate the total antioxidant capacity of the plants materials. Antibacterial activity was measured on serotyped bacteria (4) and pathogenic bacteria (13) using the solid agar dishes diffusion method. Polyphenolic quantification was measured using Folin-Ciocalteu, ammonium citrate iron and AlCl3 reagents, respectively. Fe (III) to iron (II) reducing activity show to be relate to tannins content and the radical scavenging activity by total phenolic and total flavonols. As a whole Duranta erecta L. gave a better antioxidant activity (FRAP: 15.03 mmol EAA/g and IC50: 7.88 mmol EAA/g). The best antimicrobial activity was obtained by Duranta erecta L. (22.33 mm) at a concentration of 25 μg/mL. This result was obtained on Gram-positive bacteria such as Staphylococcus épidermidis. The results obtained in this study showed an interesting antioxidant activity of Duranta erecta L. This plant also presented the best antibacterial activity particularly on Staphylococcus épidermidis, among the five species of Verbenaceae family. Our findings could partially justify the traditional uses of these plants as indicated in the literature.
Polyphenol Content and Antioxidant Activity of Fourteen Wild Edible Fruits from Burkina Faso
Aline Lamien-Meda,Charles Euloge Lamien,Moussa M.Y. Compaoré,Roland N.T. Meda,Martin Kiendrebeogo,Boukare Zeba,Jeanne F. Millogo,Odile G. Nacoulma
Molecules , 2008, DOI: 10.3390/molecules13030581
Abstract: A total of fourteen (14) species of wild edible fruits from Burkina Faso wereanalyzed for their phenolic and flavonoid contents, and their antioxidant activities usingthe DPPH, FRAP and ABTS methods. The data obtained show that the total phenolic andtotal flavonoid levels were significantly higher in the acetone than in the methanol extracts.Detarium microcarpum fruit had the highest phenolic and the highest flavonoid content,followed by that of Adansonia digitata, Ziziphus mauritiana, Ximenia americana andLannea microcarpa. Significant amounts of total phenolics were also detected in the otherfruit species in the following order of decreasing levels: Tamarindus indica > Sclerocaryabirrea > Dialium guineense > Gardenia erubescens > Diospyros mespiliformis > Parkiabiglobosa > Ficus sycomorus > Vitellaria paradoxa. Detarium microcarpum fruit alsoshowed the highest antioxidant activity using the three antioxidant assays. Fruits with highantioxidant activities were also found to possess high phenolic and flavonoid contents.There was a strong correlation between total phenolic and flavonoid levels and antioxidantactivities.
Use of anti-PGL-1 antibodies to monitor therapy regimes in leprosy patients
Zenha, E.M.R.;Ferreira, M.A.N.;Foss, N.T.;
Brazilian Journal of Medical and Biological Research , 2009, DOI: 10.1590/S0100-879X2009001000016
Abstract: the suitability of igm antibodies to pgl-1 for monitoring the response to multidrug therapy (mdt) was sequentially tested by elisa in 105 leprosy patients, and bacterial indexes (bi) were also determined. patients were divided into 3 groups: group 1, 34 multibacillary (mb) patients treated for 12 months with mdt-mb; group 2, 33 mb patients treated for 24 months with mdt-mb, and group 3, 38 paucibacillary (pb) patients treated for 6 months with mdt-pb. untreated mb patients exhibited higher antibody levels (mean ± sem): group 1 (6.95 ± 1.35) and group 2 (12.53 ± 2.02) than untreated pb patients (1.28 ± 0.35). there was a significant difference (p < 0.01) in anti-pgl-1 levels in group 1 patients: untreated (6.95 ± 1.35) and treated for 12 months (2.78 ± 0.69) and in group 2 patients: untreated (12.53 ± 2.02) and treated for 24 months (2.62 ± 0.79). there was no significant difference between untreated (1.28 ± 0.35) and treated (0.62 ± 0.12) pb patients. antibody levels correlated with bi. the correlation coefficient (pearson’s r) was 0.72 before and 0.23 (p < 0.05) after treatment in group 1 and 0.67 before and 0.96 (p < 0.05) after treatment in group 2. bi was significantly reduced (p < 0.01) after 12 and 24 months on mdt (group 1: 1.26-0.26; group 2: 1.66-0.36). our data indicate that monitoring anti-pgl-1 levels during mdt may be a sensitive tool for evaluating treatment efficacy. these data also indicate that the control of leprosy infection can be obtained with 12 months of mdt in mb patients.
Periodic variability of spotted M dwarfs in WTS
Goulding N.T.,Barnes J.R.,Pinfield D.J.,del Burgo C.
EPJ Web of Conferences , 2013, DOI: 10.1051/epjconf/20134701006
Abstract: We present an analysis of the photometric variability of M dwarfs in the WFCAM Transit Survey, selected from spectral types inferred by their WTS and SDSS colours, with periods detected using a Lomb-Scargle Periodogram Analisys. We estimate population membership of these objects from their tangential velocities and photometric parralaxes. Examples of M dwarfs with variable light curve morphologuies are found. We discuss possible causes for this and make use of models of spotted stars in our interpretation of the results.
Investigations into the safety and immunogenicity of a killed oral cholera vaccine developed in Viet Nam
Trach D.D.,Cam P.D.,Ke N.T.,Rao M.R.
Bulletin of the World Health Organization , 2002,
Abstract: OBJECTIVE: To evaluate a killed oral cholera vaccine produced in Viet Nam, and to compare the Vietnamese vaccine with one that is licensed internationally. METHOD: Two-dose regimens of a locally produced, bivalent, anti-O1, anti-O139 killed oral whole-cell cholera vaccine (biv-WC) and of a commercially available, monovalent (anti-O1) oral recombinant B subunit-killed whole-cell cholera vaccine (rBS-WC) were compared in two trials in Viet Nam. In the first trial, 144 adults were randomized to biv-WC with or without buffer, rBS-WC with buffer, or placebo without buffer. In the second, 103 children aged 1-12 years were randomized to biv-WC without buffer, rBS-WC with buffer, or placebo without buffer. FINDINGS: No regimen was associated with significant side-effects. In adults, ca 60% of recipients of either vaccine exhibited at least fourfold serum anti-O1 vibriocidal antibody responses and ca 40% of recipients of biv-WC demonstrated anti-O139 vibriocidal responses. Both anti-O1 (ca 90% in each vaccine groupand anti-O139 (68% in the biv-WC group) vibriocidal responses occurred more frequently in children. The responses to biv-WC were unaffected by the receipt of buffer. CONCLUSION: It was concluded that biv-WC was safe and immunogenic, that it could be administered without buffer, and that it could elicit robust immune responses even in children, for whom the risk of endemic cholera is highest.
A Fuzzy Clustering Approach to Filter Spam E-Mail
N.T. Mohammad
Lecture Notes in Engineering and Computer Science , 2011,
Creative poetry workshop as a means to develop creativity and provide psychological security of a teacher
N.T. Oganesyan
Psihologi?eskaa Nauka i Obrazovanie , 2013,
Abstract: A creative approach to the implementation of the Federal state standard of general education implies a supportive psychologically safe learning environment, professional readiness of educators to teaching, expressed in creativity, emotional stability, as well as reflection. The teachers’ creativity and psychological stability level can be improved by the use of certain forms of work: training and creative poetry workshops. The results of the author's research suggest that participation in the poetry workshops stimulates reflection, increases stress resistance and creativity of teachers. Our approach allows us to consider the problem of stimulating the development of teachers’ personality as members of creative poetic process in theoretical and practice oriented perspective.
Protective effect of maternal prenatal melatonin administration on rat pups born to mothers submitted to constant light during gestation
Cisternas, C.D.;Compagnucci, M.V.;Conti, N.R.;Ponce, R.H.;Vermouth, N.T.;
Brazilian Journal of Medical and Biological Research , 2010, DOI: 10.1590/S0100-879X2010007500083
Abstract: we studied the effects of adverse conditions such as constant light (ll) on the circadian rhythm of malate (mdh, ec and lactate (ldh, ec dehydrogenase activities of the testes of male wistar rats on postnatal day 28 (pn28), anxiety-like behavior (elevated plus-maze test) at pn60 and sexual behavior at pn120. the rats were assigned to mother groups on day 10 of pregnancy: control (12-h light/dark), ll (light from day 10 to 21 of pregnancy), and ll+mel (ll and sc injection to the mothers of a daily dose of melatonin, 1 mg/kg body weight at circadian time 12, from day 17 to 21 of pregnancy). ll offspring did not show circadian rhythms of mdh (n = 62) and ldh (n = 63) activities (cosinor and anova-lsd fisher). they presented a 44.7% decrease in open-arm entries and a 67.9% decrease in time (plus-maze test, n = 15, p < 0.001, mann-whitney u-test and kruskal-wallis test), an increase in mounting (94.4%), intromission (94.5%) and ejaculation (56.6%) latencies (n = 12, p < 0.01, mann-whitney u-test and kruskal-wallis test) and lower numbers of these events (61, 59 and 73%, respectively; p < 0.01, n = 12) compared to controls. the offspring of the ll+mel group presented mdh and ldh circadian rhythms (p < 0.05, n = 50, cosinor and anova-lsd fisher), anxiety-like and sexual behaviors similar to control. these findings supported the importance of the melatonin signal and provide evidence for the protective effects of hormones on maternal programming during gestation. this protective action of melatonin is probably related to its entrainment capacity, favoring internal coupling of the fetal multioscillatory system.
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