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The Association Between Serum Chemerin Concentration and Polycystic Ovarian Syndrome
S Haghighi,P Yaghmaei,F Hashemi,N Saadati
Tehran University Medical Journal , 2012,
Abstract: Background: Adipokines are proteins which are secreted from the adipose tissue. These groups of proteins are involved in the control of metabolism. Chemerin is one of these adipokines with different proposed biological roles. Serum levels of chemerin have been associated with increased body mass index, insulin resistance, metabolic syndrome, diabetes and cardiovascular diseases. The aim of this study was to assess the association between serum chemerin concentrations and polycystic ovarian syndrome. Methods: This case-control study was performed in Taleghani Hospital in Tehran, Iran during 2011. On 45 patients with polycystic ovarian syndrome and 45 normal individuals as the control group. The participants were selected by easy given sampling method. Body mass index, fasting chemerin and serum insulin concentrations were measured by Enzyme-Linked Immunosorbent Assay (ELIZA) method. Fasting serum glucose was measured by the enzyme-calorimetric method and insulin resistance index (HOMA-IR) was measured by the calculation of relevant equation. Data was analyzed using independent t-test and Pearsons correlation coefficient by SPSS version 18. Results: Serum chemerin, insulin, and glucose concentrations were significantly higher in patients with polycystic ovarian syndrome than the control group. There was no significant correlation between body mass index, serum levels of insulin, glucose, HOMA-IR, or chemerin in cases and controls. Conclusion: This study showed that serum chemerin levels increase in polycystic ovarian syndrome. The findings also suggest that changes in chemerin serum levels could be considered as a criterion for polycystic ovarian syndrome.
Evaluation of Levamisole Administration at Dry Period for Controlling Postpartum Bovine Mastitis
Farzaneh N,Rad M,Mohri M,Saadati J
Acta Veterinaria Scandinavica , 2003, DOI: 10.1186/1751-0147-44-s1-p115
Abstract:
Effects of Exercise on Memory Retrieval in Passive Avoidance Learning in Young Male Wistar Rats
H. Saadati,Sh. Babri,N. Ahmadiasl,M. Mashhadi
Qom University of Medical Sciences Journal , 2009,
Abstract: Background and ObjectivesExercise seems to be a simple and widely practiced behavior that activates molecular and cellular signaling cascades involved in various central nervous system processes. There has been more attention to the effects of exercise on nervous system and memory during recent years. So, we decided to examine the effects of treadmill exercise on memory consolidation and retrieval in young rats by passive avoidance learning.MethodsIn this study fifty male Wistar rats (3-4 months old) were randomly divided into five groups (n=10). Those in the control group were trained in passive avoidance box and tested 10 min, 24 hrs, 10 days and 3 months later. Two groups exercised in treadmill one hour at 17 m/min for 10 days and 3 months respectively and then were trained in passive avoidance box and tested 10 min and 24 hrs later. Data were analyzed using T and paired T tests. The other two groups for research effects of exercise in memory retrieval first were trained and tested 10 days and 24 hrs later and then exercised in treadmill like the other two groups; the latter groups were tested after exercise.ResultsThe obtained results showed that short–term (10 days) and long – term(3 months) exercise before training had significant (P<0.05) effects on memory consolidation in passive avoidance learning, but no difference was observed in latency time in passive avoidance between short–term (10 days) and long–term(3 months) exercise groups after training with before exercise. ConclusionOur results showed that physical activity produced a significant enhancement on learning and memory consolidation but there were no significant effects on memory retrieval. Keywords: Exercise; Mental Recall; Exercise Test; Retention (Psychology); rat, Avoidance Learning.
A Comparative Study between the Efficacy of 17-alpha-Hydroxy Progesterone Caproate Plus Salbutamol with Magnesium Sulfate in Treatment of Preterm Labor
F. Moramezi,M. Barati,N. Saadati,S. Masihi
International Journal of Pharmacology , 2011,
Abstract: This study was a comparison between salbutamol plus 17-αHP and magnesium sulfate for the prevention of PTL. One hundred and four of patients admitted for prevention of PTL were randomly assigned to two groups having 52 patients in each group. One group was given 5 mg salbutamol in 500 mL of 5% D/S, at a dose of 10 μ min-1 to a maximum of 45 μ min-1 until contraction ceased or side effects started, then we initiated soon, 250 mg of 17-αHP, it was administrated by weekly intramuscular injection and was continued until 36 weeks 6 days or delivery. Another group was given 10 g magnesium sulfate intramuscular then 5 g every four hours until contraction ceased or side effects started. Successful tocolysis achieved similar in each group. Mean uterine contraction ceasing time in group I was 5.4 h and in group II, 16.8 h. The delay in the delivery till 37 weeks of gestation in group II was lower and this differences is due to administration of in group I.Salbutamol and magnesium sulfate are equally effective regarding delay of delivery in first 48 h, but salbutamol plus 17-αHP prevents preterm labor if be continued 36 weeks 6 days.
Comparison of Sensitivity & Specificity of Transvaginal Sonography, Saline Infusion Sonohysterography and Hysteroscopy in Evaluation of Women with Abnormal Uterine Bleeding
R Mohammad Jafary,M Barati,M Najafian,N Saadati
Journal of Shahid Sadoughi University of Medical Sciences , 2009,
Abstract: Introduction: Bleeding disorders are a common problem in daily practice, especially in premenopausal women. In our investigation, we compared the sensitivity and specificity of three different diagnostic methods Trans-vaginal sonography(TVS), saline infusion sonohystrography(SIS) and Hysteroscopy. Methods: It was a cross- sectional study with a study population of ninety-nine women suffering fromAUB attending the outpatient clinic of Imam and Razi hospital in Ahvaz- Iran. They were evaluated by three different diagnostic methods and the results were compared. This study started from March 2008 to December 2008. The sensitivity, specificity, positive predictive and negative predictive values were measured in TVS, SIS, and finally these two methods were compared with hysteroscopy (as a gold standard). Results: The sensitivity and specificity of TVS was 74.2% and 49.7%, respectively, while that of SIS was 91.6% and 86%, respectively. The positive predictive value and negative predictive value of TVS was 71.9% and 54.3%, respectively, while that of SIS was 85.9% and 85.75%, respectively. The sensitivity, specificity, the positive predictive and negative predictive values of SIS was more than TVS, and it was similar to hysteroscopy. Conclusion: The findings obtained in the present study indicate that in AUB, sensitivity, specificity, positive and negative predictive value of SIS is more than TVS and therefore can be considered as a first step for diagnosis of AUB.
Production and Evaluation of Anti-Salmonella Typhimuruim Immunoglobulin Y Isolated from Serum and Eggs Laid
M. Saadati,N. Gorbani,B. Barati,S. Nazarian
Cell Journal , 2009,
Abstract: Objective: The purpose of the study was to evaluate the production of antibodiesin serum as well as egg yolk raised against S. typhimurium and the cross-reactivityof this antibody with other enteric bacteria.Materials and Methods: White egg–laying hens were immunized with S. typhimurium,heat-killed whole cell, in Freund's adjuvant. Immunization was done with107 conlony forming unit (CFU) of bacteria per hen which was injected into thebreast muscle of lay. Specific antibodies were detected by enzyme-linked immunosorbentassay in the serum and in eggs. The serum and eggs of two adultswhite Leghorn hens were not immunized with S. typhimurium used as a control.Results: Chicken egg yolk antibodies (IgY) were raised against S. typhimuruim inthe serum as well as in eggs. The production of IgY in serum was higher than IgYproduced in egg yolk. Anti-S. typhimurium IgY cross-reacted 63%, 25% and 14%with S. typhimurium, Shigella dysenteriae and E. coli respectively.Conclusion: The findings indicate that eggs from hens immunized with S. typhimuruimhave not specific antibodies for the detection of S. typhimuruim, but theymay have the potential of being a useful source of passive immunity against thispathogen.
Effects of Exercise on Memory Retrieval in Passive Avoidance Learning in Young Male Wistar Rats
H Saadati
Qom University of Medical Sciences Journal , 2012,
Abstract: Background and Objectives Exercise seems to be a simple and widely practiced behavior that activates molecular and cellular signaling cascades involved in various central nervous system processes. There has been more attention to the effects of exercise on nervous system and memory during recent years. So, we decided to examine the effects of treadmill exercise on memory consolidation and retrieval in young rats by passive avoidance learning. Methods In this study fifty male Wistar rats (3-4 months old) were randomly divided into five groups (n=10). Those in the control group were trained in passive avoidance box and tested 10 min, 24 hrs, 10 days and 3 months later. Two groups exercised in treadmill one hour at 17 m/min for 10 days and 3 months respectively and then were trained in passive avoidance box and tested 10 min and 24 hrs later. Data were analyzed using T and paired T tests. The other two groups for research effects of exercise in memory retrieval first were trained and tested 10 days and 24 hrs later and then exercised in treadmill like the other two groups; the latter groups were tested after exercise. Results The obtained results showed that short–term (10 days) and long – term(3 months) exercise before training had significant (P<0.05) effects on memory consolidation in passive avoidance learning, but no difference was observed in latency time in passive avoidance between short–term (10 days) and long–term(3 months) exercise groups after training with before exercise. ConclusionOur results showed that physical activity produced a significant enhancement on learning and memory consolidation but there were no significant effects on memory retrieval
On the Intuitionistic fuzzy topological (metric and normed) spaces
Reza Saadati
Mathematics , 2005, DOI: 10.1016/j.chaos.2005.03.019
Abstract: In this paper, we define precompact set in intuitionistic fuzzy metric spaces and prove that any subset of an intuitionistic fuzzy metric space is compact if and only if it is precompact and complete. Also we define topologically complete intuitionistic fuzzy metrizable spaces and prove that any $G_{\delta }$ set in a complete intuitionistic fuzzy metric spaces is a topologically complete intuitionistic fuzzy metrizable space and vice versa. Finally, we define intuitionistic fuzzy normed spaces and fuzzy boundedness for linear operators and so we prove that every finite dimensional intuitionistic fuzzy normed space is complete.
Comparative analysis of chemical and thermal denatured eta-lactoglobulin AB in the presence of casein
Z. Saadati,A. Razzaghi
Advanced Studies in Biology , 2012,
Abstract:
Lattictic non-archimedean random stability of ACQ functional equation
Cho Yeol,Saadati Reza
Advances in Difference Equations , 2011,
Abstract: In this paper, we prove the generalized Hyers-Ulam stability of the following additive-cubic-quartic functional equation 1 1 f ( x + 2 y ) + 1 1 f ( x - 2 y ) = 4 4 f ( x + y ) + 4 4 f ( x - y ) + 1 2 f ( 3 y ) - 4 8 f ( 2 y ) + 6 0 f ( y ) - 6 6 f ( x ) in various complete lattictic random normed spaces. Mathematics Subject Classification (2000) Primary 54E40; Secondary 39B82, 46S50, 46S40.
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