oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 10 of 1034 matches for " Murthy Rallapalli "
All listed articles are free for downloading (OA Articles)
Page 1 /1034
Display every page Item
Privacy Policies Considerations in Socio-Technical Systems  [PDF]
Murthy Rallapalli
Technology and Investment (TI) , 2012, DOI: 10.4236/ti.2012.32009
Abstract: The idea of a socio-technical system (STS) is an intellectual tool to help recognize patterns in the way technology is used and produced. Identification of these patterns will help in analyzing the ethical issues associated with the technology-and-its-social-system [1]. By way of example, consider a relatively simple technology: a set of twenty laptops connected by a local area network. The social and ethical issues associated with these networked devices will change dramatically depending upon the socio-technical system in which they are embedded. Few technologies have ever had the capability of gathering information (with or without the user’s knowledge) as effectively as the World Wide Web. Internet has the greatest potential of targeting precise marketing demographics. Internet is also capable of disseminating information widely and quickly. This paper will study the role of privacy policies in web based socio-technical systems. This paper will research the role played by privacy policies in web user adaptation in the context of web based sociotechnical systems.
Privacy Negotiation in Socio-Technical Systems  [PDF]
Murthy Rallapalli, Dinesh Verma
Technology and Investment (TI) , 2012, DOI: 10.4236/ti.2012.31003
Abstract: A socio-technical system (STS) is an approach to complex organizational work design that recognizes the interaction between people and technology in workplaces. The term also refers to the interaction between society’s complex infra-structures and human behavior. In this sense, society itself, and most of its substructures, are complex socio-technical systems. This paper addresses a class of socio-technical systems, represented by web services in a number of domains and attempts to understand the possibility of empowering the web users and consumers to have a say in the develop-ment of privacy agreements. This paper examines the likelihood of the web users and consumers leveraging such a capability, should it exist. This should improve the way privacy agreements are handled that benefits both the service providers and the web users.
Validation of multiplex PCR strategy for simultaneous detection and identification of methicillin resistant Staphylococcus aureus
Rallapalli S,Verghese S,Verma R
Indian Journal of Medical Microbiology , 2008,
Abstract: Multiplex polymerase chain reaction (PCR) strategy is described for rapid identification of clinically relevant methicillin resistant Staphylococcus aureus (MRSA) that targets mecA and coag ulase genes. In this study, 150 staphylococcal clinical isolates were used that included 40 isolates of MRSA, 55 isolates of methicillin susceptible S. aureus (MSSA), 44 isolates of methicillin susceptible coag ulase negative Staphylococcus spp. (MS-CoNS) and 11 isolates of methicillin resistant coag ulase negative Staphylococcus spp. (MR-CoNS). Out of 55 S. aureus strains, three strains demonstrated mecA gene, which appeared to be oxacillin sensitive by disc diffusion. When (MS-CoNS) were evaluated, 10 isolates classified as oxacillin sensitive phenotypically, yielded positive results in PCR method. The results for mecA detection by PCR were more consistent with disk susceptibility tests in case of MRSA (100%) and MSSA (95%) isolates. In contrast to above results with MRSA and MSSA, mecA detection by PCR in MS-CoNS showed less correlation with disk susceptibility tests (77%). The results for coag detection by PCR were consistent with phenotypic tests in all isolates.
Surgical Management of Spondylolisthesis by Pedicular Screw Rod System and Postero-Lateral Fusion  [PDF]
M. Chaitanya, Ankur Mittal, Ramprasad Rallapalli, Ravi Teja, Y. Siva Prasad
Open Journal of Orthopedics (OJO) , 2015, DOI: 10.4236/ojo.2015.56022
Abstract: Introduction: Incidence of spondylolisthesis in general population is 5% - 7%. No matter what the etiology is, patients usually have significant functional disability. Few studies have investigated the long term effect of posterolateral fusion on functional outcome. Objectives: To study the efficacy of posterolateral fusion in spondylolisthesis especially in terms of functional outcome. Methodology: From July 2010 to June 2012, a total of 86 patients, operated with postero-lateral fusion were followed up and evaluated based on VAS for low back pain, ODI and neurological deficits. Results: Follow up was 83% of original study population (86). Average follow up was 13 months. The mean difference between pre-operative and post-operative VAS at final follow up was 3.5 cms (SD = 2.94); ODI was 28% at 4 months and 36% at 8 months. Claudication pain relieved in all; functional outcome was good in 67%, fair in 27.5% and failed in 5.5%; 75% had fusion at an average of 5.5 months. Conclusion: Posteriolateral fusion is still a safe, promising and appealing technique.
Palynomorphs and Oribatid Mites—From the Denwa Formation, Satpura Basin, Madhya Pradesh, India  [PDF]
Vijaya Vijaya, Srikanta Murthy
International Journal of Geosciences (IJG) , 2012, DOI: 10.4236/ijg.2012.31022
Abstract: Palynological investigation of the Denwa Formation exposed along Denwa river succession at Saptadara picnic point near village Jhirpa, Satpura Basin, Madhya Pradesh, has revealed the presence of spore-pollen, fungal remains and Oribatid mites. Here, the mites are on record for the first time. Presence of fungal remains strongly depicts the prevalence of a very humid climate with high temperature and rainfall in the region. Poor occurrence of spore-pollen restricts the age determination of the studied section; hence, its age assessment is relative. Thus, an over-view of spore-pollen along with dinocysts and insects reported earlier from the subsurface strata comprising Denwa Formation, from other two localities in the nearby area of village Anhoni, is dealt herein, and that had inferred an age—range from Carnian to Rhaetic for the palynoflora and fauna.
Orbital Spin: A New Hypothesis to Explain Precession of Equinox—The Third Motion of Earth  [PDF]
Rama Chandra Murthy Mothe
International Journal of Astronomy and Astrophysics (IJAA) , 2014, DOI: 10.4236/ijaa.2014.41004
Abstract:

In this paper, the phenomena of Earth’s motion about its own axis, the ecliptic plane of the Earth’s orbit around the Sun, the definitions of equinoxes, the precession of equinoxes, Earth’s wobble and other astronomical terminology are briefly described. Some of the existing theories explaining the precession of equinox and their inadequacies are brought out. New Hypothesis is that precession of equinoxes is a direct result of Orbital spin of Earth in a retrograde direction—a celestial phenomenon similar to that of Moon’s Orbital spin around the Earth. The study of Moon’s orbit round the Earth reveals the exact movement of Earth’s orbit, which causes precession of equinoxes without any ambiguity. The analogy presented herein demonstrates the plausible hypothesis.

Cardiac Sarcolemmal Defects in Acute Myocarditis Due to Scorpion Envenoming Syndrome  [PDF]
K. Radha Krishna Murthy
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.49054
Abstract:

Death due to scorpion envenoming syndrome is a common event in tropical and subtropical countries. Severe scorpion envenoming causes autonomic storm, massive release of catecholamines, counter-regulatory hormones, suppressed insulin/hyperinsulinemia, acute myocarditis, hyperglycemia, increased free fatty Acid levels, acute pancreatitis, disseminated intra-vascular coagulation, acute pulmonary oedema and death. Severe scorpion envenoming causes cardiac sarcolemmal defects displayed by alterations in Na+ - K+ ATPase, Mg++ ATPase and Ca2+ ATPase activities, inhibition of erythrocyte Na+ - K+ ATPase activities, hyperkalemia and may result in death. Based on our animal experiments in which insulin administration reversed the metabolic and ECG changes induced by scorpion envenoming and treating the poisonous scorpion sting victims with insulin, we consider that insulin has a primary metabolic role in preventing and reversing acute myocarditis, the cardiovascular, haemodynamic, and neurological manifestations and pulmonary oedema induced by scorpion envenoming. Administration of insulin-glucose infusion to scorpion sting victims appears to be the physiological basis for the control of the metabolic response when that has become a determinant to survival. Continuous infusion of regular crystalline insulin should be given at the rate of 0.3 U/g glucose and glucose at the rate of 0.1 g/kg body weight/hour, for 48 - 72 hours, with supplementation of potassium as needed and maintenance of fluid, electrolytes and acid-base balance. The observation of cardiac sarcolemmal defects and physiological basis of various patho-physiological mechanisms involved in the genesis of scorpion envenoming syndrome and its reversal (in the experimental animals and scorpion sting victims) by administration of insulin are reviewed.

Hypertension, Autonomic Storm, Increased Counter Regulatory Hormones and Suppressed Insulin in Acute Myocarditis in Scorpion Envenoming Syndrome  [PDF]
Kari Radha Krishna Murthy
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.44027
Abstract: Death due to scorpion envenoming syndrome is a common event in many of the tropical and non-tropical counties. Initial transient hypertension is commonly observed in scorpion sting victims. Scorpion envenoming causes autonomic storm resulting in initial transient hypertension followed by hypotension, cold clammy skin, hypothermia, cardiovascular disturbances, acute myocarditis, sarcolemmal defects, pulmonary oedema, acute pancreatitis, disseminated intravascular coagulation (DIC), Adult respiratory distress syndrome (ARDS), and many other clinical manifestations. All these manifestations could be due to sudden increase in catecholamines, angiotensin II, glucagon, Cortisol and either due to suppressed insulin secretion or insulin resistance and death. The sudden increase of metabolic A in counter-regulatory hormones along with either suppressed insulin secretion/or insulin resistance results in glycogenolysis in liver, cardiac and skeletal muscles causing hyperglycemia and a sudden increase in free fatty acid levels. Free Fatty Acids increase the susceptibility of the ventricles to the disorganized electrical behavior, inhibit cardiac sarcolemmal Na+-K+ ATPase activity, increase the tendency to intravascular thrombus, increase myocardial oxygen consumption, interfere with tropomyosin-troponin activation of Actin-Myosin coupling, show detergent effects on cell membranes and they could alter the stabilization of lysosomal membranes and probably become toxic to the myocardium. Based on our animal experiments in which insulin administration reversed the metabolic and ECG changes induced by scorpion envenoming and treating the poisonous scorpion sting victims with insulin, we consider that insulin has a primary metabolic role in preventing, counter-acting and reversing all the deleterious effects of FFA by inhibiting the catecholamine induced by lipolysis, and increasing intra-cellular K+, facilitating glucose transport to the myocardium and glucose metabolism through different pathways. Administration of insulin-glucose infusion to scorpion sting victims appears to be the physiological basis for the control of the metabolic response when that has become a determinant to survival. Treatment using continuous infusion of regular crystalline insulin should be given at the rate of 0.3 U/g glucose and glucose at the rate of 0.1 g/kg body weight/hour, for 48 - 72 hours, with supplementation of potassium as needed and maintenance of fluid, electrolytes and acid-base balance.
Innovative Structured Matrices  [PDF]
Rahul Gupta, Garimella Rama Murthy
Advances in Linear Algebra & Matrix Theory (ALAMT) , 2013, DOI: 10.4236/alamt.2013.33004
Abstract:

Various directions of obtaining novel structured matrices are discussed. A new class of matrices, called “the L-family” matrices are introduced and their properties are studied.

Transdermal drug delivery: approaches and significance
Murthy SN
Research and Reports in Transdermal Drug Delivery , 2012, DOI: http://dx.doi.org/10.2147/RRTD.S31738
Abstract: Transdermal drug delivery: approaches and significance Editorial (2057) Total Article Views Authors: Murthy SN Published Date May 2012 Volume 2012:1 Pages 1 - 2 DOI: http://dx.doi.org/10.2147/RRTD.S31738 Received: 13 March 2012 Accepted: 13 March 2012 Published: 03 May 2012 S Narasimha Murthy Department of Pharmaceutics, The University of Mississippi, USA Transdermal drug delivery systems deliver drugs through the skin as an alternative to oral, intravascular, subcutaneous, and transmucosal routes. Potential advantages of transdermal delivery include, but are not limited to, elimination of first-pass metabolism, steady delivery/blood levels, better patient compliance, reduced systemic drug interactions, possible dose intervention, avoidance of medically assisted drug administration, prolonged drug administration, and overall better therapeutic efficacy. Post to: Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter Readers of this article also read: Applications of gold nanoparticles in cancer nanotechnology Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology Subset-directed antiviral treatment of 142 herpesvirus patients with chronic fatigue syndrome DataGenno: building a new tool to bridge molecular and clinical genetics Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi Differences in risk aversion between young and older adults The preparation and characterization of gold-conjugated polyphenol nanoparticles as a novel delivery system Nanocarriers for transdermal drug delivery
Page 1 /1034
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.