oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 23 )

2019 ( 264 )

2018 ( 259 )

2017 ( 226 )

Custom range...

Search Results: 1 - 10 of 112193 matches for " Munhoz Derli Concei??o "
All listed articles are free for downloading (OA Articles)
Page 1 /112193
Display every page Item
Compara??o entre os efeitos hemodinamicos da intoxica??o aguda com bupivacaína racêmica e a mistura com excesso enatiomérico de 50% (S75-R25): estudo experimental em c?es
Udelsmann, Artur;Munhoz, Derli Concei??o;Silva, William Adalberto;Moraes, Ana Cristina de;Marcondes, Giancarlo;
Revista Brasileira de Anestesiologia , 2006, DOI: 10.1590/S0034-70942006000400007
Abstract: background and objectives: racemic bupivacaine has been widely used in locoregional anesthesia due to the quality and duration of its anesthetic action. however, its cardiovascular toxicity has worried anesthesiologists for a long time, and new options have been sought. one of them is the use of its levorotatory isomer that, due to a lesser affinity for the sodium channel receptors in the cardiac cell, would be less toxic. the presentation containing 75% of the levorotatory isomer and 25% of the dextrorotatory isomer, named 50% enantiomeric excess mixture (s75-r25), is available in our country. the objective of this study was to compare the hemodynamic effects of the acute intoxication with racemic bupivacaine and with the s75-r25 mixture in animals. methods: forty-four dogs were anesthetized with pentobarbital, intubated and placed on mechanical ventilation. hemodynamic monitorization was accomplished with a swan-ganz catheter and intra-arterial blood pressure measurements. after a period of rest, they were randomly and blindly divided in two groups, according to the intoxication with either agent at a dose of 5 mg.kg-1. hemodynamic data were collected during 30 minutes and analyzed statically to allow for the comparison of both agents. results: the mixture s75-r25 had more hemodynamic repercussions causing, especially, a significant reduction of the mean arterial pressure, cardiac index, and the left ventricle work index. conclusions: these results contradict those found in human beings regarding the pure levorotatory isomer, but confirm recent animal studies. one must be very careful when extrapolating animal data to human beings. further studies involving larger samples and more homogeneous groups are necessary.
Influência do propofol e do etomidato no bloqueio neuromuscular produzido pelo rocur?nio: avalia??o pela aceleromiografia
Munhoz, Derli Concei??o;Braga, Angélica de Fátima de Assun??o;Potério, Glória Maria Braga;
Revista Brasileira de Anestesiologia , 2002, DOI: 10.1590/S0034-70942002000600003
Abstract: background and objectives: some hypnotics may interact with neuromuscular blockers and potentiate their effects. this study aimed at evaluating the influence of propofol and etomidate on rocuronium-induced neuromuscular block. methods: participated in this study 60 patients, physical status asa i and ii, scheduled for elective surgeries under general anesthesia, who were randomly distributed in two groups according to the hypnotic drug: group i (propofol) and group ii (etomidate). all patients were premedicated with intramuscular midazolam (0.1 mg.kg-1), 30 minutes before surgery. anesthesia was induced with propofol (2.5 mg.kg-1) or etomidate (0.3 mg.kg-1) preceded by alfentanil (50 μg.kg-1) and followed by rocuronium (0.6 mg.kg-1). patients were ventilated under mask with 100% oxygen until achieving a decrease of 75% or more in the adductor pollicis muscle response amplitude. neuromuscular function was monitored by accelerometry. the following parameters were evaluated: rocuronium onset (t1 £ 25%); time for complete neuromuscular block; neuromuscular block degree at tracheal intubation; tracheal intubation conditions and hemodynamic effects. results: complete rocuronium-induced neuromuscular block onset times (in seconds) were: group i (48.20 ± 10.85 s and 58.87 ± 10.73 s) and group ii (51.20 ± 13.80 s and 64.27 ± 18.55 s). neuromuscular block degree at tracheal intubation was: group i (77.50%) and group ii (76.96%). tracheal intubation conditions were satisfactory in 100% of group i patients and in 83.33% of group ii patients. there has been a significant decrease in mean blood pressure, followed by an increase after hypnotic injection, in both groups. conclusions: propofol and etomidate had a similar behavior regarding time for rocuronium-induced neuromuscular block and tracheal intubation conditions.
Influência do propofol e do etomidato no bloqueio neuromuscular produzido pelo rocur nio: avalia o pela aceleromiografia
Munhoz Derli Concei??o,Braga Angélica de Fátima de Assun??o,Potério Glória Maria Braga
Revista Brasileira de Anestesiologia , 2002,
Abstract: JUSTIFICATIVA E OBJETIVOS: Alguns hipnóticos podem interagir com os bloqueadores neuromusculares (BNM) potencializando seus efeitos. O objetivo deste estudo foi avaliar a influência do propofol e do etomidato sobre o bloqueio neuromuscular produzido pelo rocur nio. MéTODO: Foram incluídos no estudo 60 pacientes, estado físico ASA I e II, submetidos a cirurgias eletivas sob anestesia geral, distribuídos aleatoriamente em dois grupos de acordo com o hipnótico empregado: Grupo I (propofol) e Grupo II (etomidato). Todos os pacientes receberam midazolam (0,1 mg.kg-1) por via muscular como medica o pré-anestésica, 30 minutos antes da cirurgia. A indu o anestésica foi obtida com propofol (2,5 mg.kg-1) ou etomidato (0,3 mg.kg-1) precedido de alfentanil (50 μg.kg-1) e seguido de rocur nio (0,6 mg.kg-1). Os pacientes foram ventilados sob máscara com oxigênio a 100% até a obten o de redu o de 75% ou mais na amplitude da resposta do músculo adutor do polegar, quando foram realizadas as manobras de laringoscopia e intuba o traqueal. A fun o neuromuscular foi monitorizada com aceleromiografia. Foram avaliados: tempo de início de a o do rocur nio (T1 <= 25%); tempo para instala o do bloqueio neuromuscular total; grau de bloqueio neuromuscular no momento da intuba o traqueal; condi es de intuba o traqueal e repercuss es hemodinamicas. RESULTADOS: Os tempos de início de a o e instala o de bloqueio neuromuscular total (segundos) produzido pelo rocur nio foram: Grupo I (48,20 ± 10,85 s e 58,87 ± 10,73 s) e Grupo II (51,20 ± 13,80 s e 64,27 ± 18,55 s). O grau de bloqueio neuromuscular no momento da intuba o traqueal foi: Grupo I (77,50%) e Grupo II (76,96%). As condi es de intuba o traqueal foram satisfatórias em 100% dos pacientes do Grupo I e em 83,33% no Grupo II. Nos dois grupos, após a inje o do hipnótico, observou-se diminui o significativa da press o arterial média seguida de eleva o. CONCLUS ES: O propofol e o etomidato comportaram-se de maneira semelhante em rela o à instala o do bloqueio neuromuscular e às condi es de intuba o traqueal produzidos pelo rocur nio.
Efeitos hemodinamicos da oclus?o da aorta durante anestesia inalatória com isoflurano e sevoflurano: estudo experimental em c?es
Udelsmann, Artur;Munhoz, Derli Concei??o;Cintra, álvaro Edmundo Sim?es Ulhoa;Santos, José Eduardo Tanus dos;
Revista Brasileira de Anestesiologia , 2006, DOI: 10.1590/S0034-70942006000300004
Abstract: background and objectives: aortic flow suppression and release during aortic procedures promote major hemodynamic disorders. this study aimed at evaluating these disorders in dogs anesthetized with isoflurane or sevoflurane. methods: this study involved 41 dogs divided in two groups according to the anesthetic agent used for maintenance with 1 mac: gi (n = 21) isoflurane; gs (n = 20) sevoflurane. aorta was occluded by intra-arterial infra-diafragmatic cuff inflation for 30 minutes. hemodynamic parameters were observed in moments m1 (control), m2 and m3, 15 and 30 minutes after aortic occlusion, m4 and m5, 15 and 30 minutes after cuff deflation. results: during aortic occlusion there has been increased mean blood pressure (mbp), central venous pressure (cvp), pulmonary artery pressure (pap), pulmonary capillary wedge pressure (pcwp) and systemic vascular resistance (svr), without increase in pulmonary vascular resistance (pvr) and cardiac output (co). co was more stable with isoflurane as compared to sevoflurane where it has decreased after occlusion. heart rate has initially decreased followed by increase during occlusion, being more expressive in gs as compared to gi, however without statistically significant difference between groups. systolic volume was not importantly changed; left and right ventricular function have similarly increased after occlusion for both groups. with flow release, mbp, cvp, pap, pcwp and svr have decreased, and pvr has increased for both groups; ventricular function has abruptly decreased. conclusions: this study has shown that isoflurane is a better indication for such interventions for promoting less hemodynamic changes.
Metadona e morfina na indu??o da anestesia em cirurgia cardíaca: repercuss?o na analgesia pós-operatória e prevalência de náuseas e v?mitos
Udelsmann, Artur;Maciel, Fernanda Gardini;Servian, Derli Concei??o Munhoz;Reis, Eder;Azevedo, Teresinha Maria de;Melo, Marcos De Simone;
Revista Brasileira de Anestesiologia , 2011, DOI: 10.1590/S0034-70942011000600001
Abstract: background and objectives: pain is an aggravating factor in postoperative morbidity and mortality especially in large size surgeries. methods to effectively fend pain collide with elevated costs and for this reason they are not accessible in every service. the option would be the use of an opioid with long half-life, such as methadone. the objective of the present study was to compare the requirements of postoperative analgesia in patients who received methadone, morphine, or placebo during anesthetic induction, besides the prevalence of postoperative nausea and vomiting. methods: fifty-five patients scheduled for cardiac surgery were divided into three groups and they received during anesthetic induction 20 mg of methadone, 20 mg of morphine, or placebo. at the end of surgery, patients were transferred to the icu where the following parameters were evaluated: duration of anesthesia, time until extubation, time until the need of the first analgesic, number of doses required in 24 hours, assessment of analgesia by the patient, and prevalence of nausea/vomiting. results: differences in the duration of anesthesia and time until extubation were not observed. the first dose of analgesic in patients who received methadone was administered later than in patients in the other two groups. the need of analgesics in the methadone group was lower, quality of analgesia was better, and prevalence of nausea and vomiting was also lower. conclusions: methadone during anesthetic induction was effective for analgesia in large size surgeries. lower incidence of nausea and vomiting was observed in the methadone group and therefore it is a low cost option available among us that should be stimulated.
Efeitos hemodinamicos da oclus o da aorta durante anestesia inalatória com isoflurano e sevoflurano: estudo experimental em c es
Udelsmann Artur,Munhoz Derli Concei??o,Cintra álvaro Edmundo Sim?es Ulhoa,Santos José Eduardo Tanus dos
Revista Brasileira de Anestesiologia , 2006,
Abstract: JUSTIFICATIVA E OBJETIVOS: A supress o do fluxo aórtico e sua posterior libera o em interven es cirúrgicas da aorta ocasionam importantes distúrbios hemodinamicos. O objetivo deste estudo foi avaliar essas altera es em c es anestesiados com isoflurano ou sevoflurano. MéTODO: Foram estudados 41 c es, divididos em dois grupos segundo o anestésico empregado na manuten o com 1 CAM: GI (n = 21) isoflurano; GS (n = 20) sevoflurano. Foi realizada a oclus o aórtica por insufla o de bal o intra-arterial infradiafragmático por 30 minutos. Os parametros hemodinamicos foram observados nos momentos M1 (controle), M2 e M3, 15 e 30 minutos após a oclus o aórtica, M4 e M5, 15 e 30 minutos após a desinsufla o do bal o. RESULTADOS: Durante a oclus o da aorta, observou-se aumento da press o arterial média (PAM), da press o venosa central (PVC), da press o de artéria pulmonar (PAP), da press o de capilar pulmonar (PCP) e da resistência vascular sistêmica (RVS) sem aumento da resistência vascular pulmonar (RVP) e do débito cardíaco (DC). O DC manteve-se mais estável com o isoflurano comparado com o sevoflurano, com o qual apresentou diminui o após a oclus o. A freqüência cardíaca teve diminui o inicial seguida de aumento durante a oclus o sendo em GS mais expressiva do que em GI, porém sem diferen a significativa entre os grupos. O volume sistólico n o teve grandes altera es; o trabalho sistólico dos ventrículos esquerdo e direito aumentou após a oclus o de forma semelhante nos dois grupos. Com a libera o do fluxo PAM, PVC, PAP, PCP e RVS diminuíram, a RVP aumentou nos dois grupos; o trabalho ventricular diminuiu abruptamente. CONCLUS ES: O estudo demonstrou ser o isoflurano mais bem indicado nessas interven es cirúrgicas por causar menores altera es hemodinamicas.
Influência da freqüência de estímulos na instala??o do bloqueio neuromuscular produzido pelo rocur?nio e pancur?nio: avalia??o pelo método acelerográfico
Munhóz, Derli da Concei??o;Braga, Angélica de Fátima de Assun??o;Potério, Glória Maria Braga;
Revista Brasileira de Anestesiologia , 2004, DOI: 10.1590/S0034-70942004000100002
Abstract: background and objectives: factors associated to patients and neuromuscular blockers (nmb), as well as others inherent to neuromuscular function monitoring, may affect neuromuscular block onset. this study aimed at the influence of two different stimulation frequencies on rocuronium and pancuronium-induced neuromuscular block. methods: participated in this study 120 patients, physical status asa i and ii, submitted to elective procedures under general anesthesia, who were randomly allocated in two groups, according to the stimulation frequency employed to monitor neuromuscular block: group i - 0.1 hz (n = 60) and group ii - 1 hz (n = 60). two subgroups were formed within each group (n = 30), according to the neuromuscular blocker: subgroup p (pancuronium) and subgroup r (rocuronium). patients were premedicated with muscular midazolam (0.1 mg.kg-1), 30 minutes before surgery. anesthesia was induced with propofol (2.5 mg.kg-1) preceded by alfentanil (50 μg.kg-1) and followed by pancuronium or rocuronium. patients were ventilated under mask with 100% oxygen until 75% or more decrease in adductor pollicis muscle response, when laryngoscopy and tracheal intubation were performed. neuromuscular function was monitored by acceleration transducer. the following parameters were evaluated: pancuronium and rocuronium onset time; time for complete block and tracheal intubation conditions. results: mean times (seconds) for pancuronium-induced neuromuscular block onset and for complete neuromuscular block were: group i (159.33 ± 35,22 and 222 ± 46.56) and group ii (77.83 ± 9.52 and 105.96 ± 15.58); rocuronium-induced values were: group i (83 ± 17.25 and 125.33 ± 20.12) and group ii (48.96 ± 10.16 and 59.83 ± 10.36) with statistical difference between groups. tracheal intubation conditions were satisfactory in 117 patients (97.5%) and unsatisfactory in 3 (2.5%). conclusions: rocuronium and pancuronium-induced neuromuscular block onset and time required for complete adductor pollici
Influência da freqüência de estímulos na instala o do bloqueio neuromuscular produzido pelo rocur nio e pancur nio: avalia o pelo método acelerográfico
Munhóz Derli da Concei??o,Braga Angélica de Fátima de Assun??o,Potério Glória Maria Braga
Revista Brasileira de Anestesiologia , 2004,
Abstract: JUSTIFICATIVA E OBJETIVOS: Fatores relacionados ao paciente e ao bloqueador neuromuscular (BNM), assim como outros inerentes à monitoriza o da fun o neuromuscular podem influenciar na instala o do bloqueio neuromuscular. O objetivo deste estudo foi avaliar a influência de duas diferentes freqüências de estímulos sobre o tempo de instala o do bloqueio produzido pelo pancur nio e pelo rocur nio. MéTODO: Foram incluídos no estudo 120 pacientes, estado físico ASA I e II, submetidos a cirurgias eletivas sob anestesia geral, distribuídos aleatoriamente em dois grupos, de acordo com a freqüência de estímulo empregada, para a monitoriza o do bloqueio neuromuscular: Grupo I - 0,1 Hz (n = 60) e Grupo II - 1 Hz (n = 60). Em cada grupo formaram-se dois subgrupos (n = 30) de acordo com o bloqueador neuromuscular empregado: Subgrupo P (pancur nio) e Subgrupo R (rocur nio). A medica o pré-anestésica consistiu de midazolam (0,1 mg.kg-1) por via muscular, 30 minutos antes da cirurgia. A indu o anestésica foi obtida com propofol (2,5 mg.kg-1) precedido de alfentanil (50 μg.kg-1) e seguido de pancur nio ou rocur nio. Os pacientes foram ventilados sob máscara com oxigênio a 100% até a obten o de redu o de 75% ou mais na amplitude da resposta do músculo adutor do polegar, quando foram realizadas as manobras de laringoscopia e intuba o traqueal. A fun o neuromuscular foi monitorizada com aceleromiografia. Foram avaliados: tempo de início de a o do pancur nio e do rocur nio; tempo para instala o do bloqueio total e condi es de intuba o traqueal. RESULTADOS: Os tempos médios (segundos) para o início de a o e instala o de bloqueio neuromuscular total produzido pelo pancur nio foram: Grupo I (159,33 ± 35,22 e 222 ± 46,56) e Grupo II (77,83 ± 9,52 e 105,96 ± 15,58); para o rocur nio: Grupo I (83 ± 17,25 e 125,33 ± 20,12) e Grupo II (48,96 ± 10,16 e 59,83 ± 10,36) com diferen a significativa entre os grupos. As condi es de intuba o traqueal foram satisfatórias em 117 pacientes (97,5%) e insatisfatórias em 3 (2,5%). CONCLUS ES: O início de a o e o tempo para obten o do bloqueio neuromuscular total no músculo adutor do polegar, produzidos pelo rocur nio e pelo pancur nio, s o mais curtos quando há emprego de maiores freqüências de estímulos.
Influence of stimulus frequency on blockade induced by pancuronium and rocuronium: study on rats phrenic nerve-diaphragm preparation
Braga, Angélica de Fátima de Assun??o;Munoz, Derli Concei??o;Braga, Franklin Sarmento da Silva;Araujo, Daniele Ribeiro de;Potério, Glória Maria Braga;Mantovani, Mario;
Acta Cirurgica Brasileira , 2007, DOI: 10.1590/S0102-86502007000600006
Abstract: purpose: to evaluate the influence of two stimulation frequencies on the installation of neuromuscular blockade produced by pancuronium and rocuronium on the rat diaphragm. methods: diaphragms were submitted to an indirect frequency stimulation of 0.1 and 1hz (groups i and ii, respectively). subgroups were formed (n=5) according to the neuromuscular blocker employed (pancuronium-2μg/ml and rocuronium-4μg/ml). the twitch height depression was evaluated at 5, 15 and 30 minutes after adding the neuromuscular blocker. results: the decrease in twitch height was greater (p<0.01) with a frequency of 1hz at all time periods studied both in preparations that are blocked with pancuronium and in those that are blocked with rocuronium. conclusion: the frequency of stimulation interferes significantly with the installation of neuromuscular blockade produced by pancuronium and rocuronium, since the reduction in amplitude of the rat diaphragm response was greater for 1hz frequencies, at all periods studied.
Inicia??o à pesquisa no Ensino Superior: desafios dos docentes no ensino dos primeiros passos
Neuenfeldt, Derli Juliano;Schuck, Rogério José;Munhoz, Angélica;Mittelstadt, Juliana;Miorando, Tania Micheline;Rochenback, Ronaldo;
Ciência & Educa??o (Bauru) , 2011, DOI: 10.1590/S1516-73132011000200003
Abstract: the aim of this descriptive research was to understand the way in which the initiation in higher education is done as professors who work with the related subjects in this area. the information was collected through seven semi-structured interviews with professors of univates. three main worries were detected: a) work with students on the comprehension of what is science and what is research; b) teaching normative writing (abtn), methods and research techniques; and c) the link between the research and the actual field of the academic student. the results show the need to deepen the students' comprehension of research and science, and that the courses and professors of other subjects should assume, conjunctly, the responsibility for scientific and ethical formation.
Page 1 /112193
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.