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Comparison of linear measurement accuracy on cone-beam computed tomography images and digital lateral cephalometric radiographs
Mozhdeh Mehdizadeh,Elham Faghihian
Journal of Isfahan Dental School , 2013,
Abstract: Introduction: Two-dimensional (2D) imaging has limitations in the evaluation of three-dimensional (3D) structures. In recent years, it has become possible to acquire 3D data of patients. This study sought to evaluate the accuracy of linear measurements of the skull made by cone-beam computed tomography (CBCT) technique and digital lateral cephalometry by two newly introduced Galileos and Planmeca machines.Materials and Methods: In this random descriptive/cross-sectional study, seven anatomical landmarks were determined on seven dry human skulls. Direct measurements on the skulls were made with a digital caliper. Then digital cephalometric radiographs and CBCT radiographs were taken. SPSS Ver. 11.5 software was used for the data analysis. ICC (Intraclass Correlations Coefficients) test and mean percentage differences was calculated.Results: The mean percentage differences between CBCT technique measurements and those made on dry skulls were less than 1 mm, less than 2 mm and 3 mm in 42%, 42% and 12% of variables. These mean differences between measurements lateral cephalometric images and those on dry skulls were less than 5 mm in 42% of cases and 10 16 mm in the remaining 42%. The mean ICC values were more valuable in the CBCT technique than those in the digital lateral cephalometry technique.Conclusion: The accuracy of CBCT was much higher than digital lateral cephalometry. No directional magnification or minifying was observed I the CBCT technique. Key words: Cone-beam computed tomography, 3-Dimentional imaging, Cephalometry
Accuracy of Cameriere method in chronological age estimation
Shahrzad Javadinejad,Mozhdeh Mehdizadeh,Reihaneh Torabi
Journal of Isfahan Dental School , 2012,
Abstract: Introduction: Various dental age estimation methods have been used, based on tooth development. In Cameriere method the distance of the apices of seven left permanent mandibular teeth is measured. The aim of this study was to compare dental age means estimated by Cameriere method and the means of chronological age. Materials and Methods: In this cross-sectional descriptive study, 109 panoramic radiographs of 67 females and 42 males aged 5 15 years were assessed. The variables included the number of teeth with full development and closed apices, the distance between the inner sides of open apices in immature teeth, and the tooth lengths. To accommodate the effect of magnification and x-ray angulation, the measurements were normalized by dividing them by tooth lengths. Finally, the normalized measurements of open apices, the sum of the normalized open apices, the number of teeth with closed apices, gender and chronological age were recorded using SPSS 18 for age estimation formula. Data were analyzed by Pearson’s correlation coefficient and independent t-test (α = 0.05). Results: Pearson’s correlation coefficient showed significant and inverse correlations between age and all the other variables. Differences between dental and chronological ages varied from -2.66 to 2.79 years. The median of chronological age was 10.67 and that of Cameriere age was 11.12 years. The difference between chronological age and estimated age was not significant (p value = 0.95). The differences between chronological and Cameriere ages were 0.73 in girls and 0.99 in boys. Estimated age was more accurate in girls (p value = 0.04). Conclusion: The present study indicated that Cameriere method was reliable for age estimation in our sample; also this method of age estimation was more accurate for girls than for boys. Key words: Age factor, Forensic dentistry, Panoramic radiograph, Tooth apex.
Evaluation of accuracy of ultrasonography in the diagnosis of zygomatic arch fractures
Mozhdeh Mehdizadeh,Moein Hoseini-Shirazi,Forouzan Farahbod
Journal of Isfahan Dental School , 2011,
Abstract: Introduction: In recent years, computed tomography (CT) scan has become an alternative to conventional radiography; however, the use of ultrasound in detecting zygomatic arch fractures has been rarely evaluated. The aim of this study was to evaluate accuracy of ultrasonography in the diagnosis of zygomatic arch fractures.Materials and methods: Fifteen patients (9 men and 6 women) with clinical signs of midfacial fractures, whose CT scan findings showed unilateral zygomatic arch fracture, were selected. All the patients underwent bilateral ultrasound examinations. All the sonographic techniques were carried out and interpreted by the same sonologist who was not aware of the CT results. Data were analyzed to determine sensitivity and specificity of ultrasonography in the diagnosis of zygomatic arch fractures.Results: Ultrasound assessed the fractured arches with a sensitivity of 100% (15 of 15 patients, with no false negatives) and the un-fractured arches with a specificity of 100% (no false positives).Conclusion: Based on the results of the present study ultrasound is a useful diagnostic tool for zygomatic arch fractures in initial investigations, and can help reduce the total number of diagnostic radiographic procedures and overall radiation exposure.Key words: Diagnosis, Fracture, Ultrasonography, Zygomatic arch.
Immunohistochemical study of correlation between histologic changes and radiologic features in pericoronal tissues of impacted wisdom teeth
Sayed Mohammad Razavi,Sara Siadat,Mozhdeh Mehdizadeh,Bijan Movahedian
Journal of Isfahan Dental School , 2012,
Abstract: Introduction: Third molars have the greatest incidence of impaction. There is no general agreement on the removal of asymptomatic impacted third molars. EGFR might be an indicator of increased potential for tumoral and cystic changes. The aim of this study was to investigate the expression of EGFR marker in the follicles of impacted wisdom teeth and its relation to radiologic features.Materials and methods: In this cross-sectional/analytical research, 40 samples of wisdom tooth follicles, embedded in paraffin blocks, were studied. After preparing the specimens and primary observation of H&E slides, immunohistochemical technique was used for expression of EGFR marker. EGFR staining pattern (membrane only, cytoplasm only or combined cytoplasm and membrane staining) was evaluated in the odontogenic epithelium of follicles. Data were analyzed with Mann-Whitney and logistic regression tests using the SPSS software (α=0.05). Results: Expression of EGFR marker with membrane-only staining pattern in follicles with radiolucencies >2.5 mm was significantly higher than follicles with radiolucencies <2.5 mm. (p value < 0.001). However, no significant differences were detected between the two groups in cytoplasm-only pattern (p value = 0.13) and combined cytoplasmic and membrane pattern (p value = 0.13). Discussion: The number and intensity of stained cells in membrane-only pattern were higher in follicles with radiolucencies >2.5 mm compared to follicles with radiolucencies <2.5 mm, indicating faster cell proliferation. Therefore, it is suggested that third molars with radiolucencies >2.5 mm be removed as soon as possible. However, the absence of abnormal radiolucency does not indicate healthy follicles without pathologic changes.Key words: Human EGFR protein, Immunohistochemistry, Impacted tooth.
Radiopacity evaluation of a new root-end filling material (NREFM) with two types of radiopacifiers in comparison to pro-root MTA and Portland cement
Ali Akhavan,Elahe Shafiei Rad,Mozhdeh Mehdizadeh,Seyed Behrouz Mousavi
Journal of Isfahan Dental School , 2012,
Abstract: Introduction: Recently a new root-end filling material (NREFM), referred to as Cold Ceramic (CC), has been introduced; different studies have shown its biocompatibility, low cytotoxicity and good sealability. One of the disadvantages of CC is its low radiopacity in clinical procedures. The aim of this study was to evaluate radiopacity of CC by incorporating different radiopacifiers (Bi2O3, BaSo4) in comparison to Pro-root MTA and PC. Materials and Methods: In this in vitro study 7 groups of materials (Group 1: 0.9 NREFM + 0.1 gr Bi2O3; Group 2: 0.8 gr NREFM + 0.2 gr Bi2O3; Group 3: 0.9 NREFM + 0.1 gr BaSo4; Group 4: 0.8 gr NREFM + 0.2 gr BaSo4; Group 5: NREFM; Group 6: Pro-root MTA; Group 7: PC) were mixed with 0.3 mL of distilled water and placed in Teflon rings measuring 10 mm in internal diameter and 1 mm in thickness, based on ISO 6876/2001 and allowed to set. The samples were placed on PSP cassettes adjacent to a step-wedge graduated aluminum plate and radiographed. The radiographic density was determined using Digora and Scannora software programs. Data were analyzed by SPSS using Kruskal-Wallis and Mann-Whitney tests (α = 0.05). Results: Group 6 exhibited the highest radiopacity (6.85 mm Al) and PC samples exhibited the lowest radiopacity (2.74 mm Al). Conclusion: All the materials tested exhibited acceptable radiopacity except for PC. A combination of 0.9 gr NREFM + 0.1 gr Bi2O3 has radiopacity comparable to that of Pro-root MTA. Key words: Aluminum, Mineral trioxide aggregate, Portland cement, Retrograde root-end obturation.
Rahimeh Mehdizadeh
Brazilian Journal of Biomotricity , 2012,
Abstract: MEHDIZADEH, R. Relationship between body water compartments and indexes of adiposity in sedentary young adult girls. Brazilian Journal of Biomotricity. v. 6, n. 2, p. 84-92, 2012. Changes in Total body water (TBW) that occur with variation of body weight (BW), indicating a relation between body water content and adipose tissue mass, because BW changes directly relate to changes in FM content in adults. The aim of the study was first to determine the relationship between TBW, extra- and intra cellular water (ECW and ICW) with some indexes of overall and central adiposity. Three hundred and forty eight young adult girls (18-24yrs) volunteered to participate in this study. After fasting for at least 12 h, body water components (TBW, ECW, and ICW), indexes of overall obesity including body mass index (BMI), body fat percentage (%BF) and fat mass (FM) and central obesity including waist-to-hip circumference ratio (WHR) were measured by Body Composition Analyzer. There were significant positive correlations between WHR, FM and %BF with body water compartments including TBW (P<0.01), ECW (P<0.01) and ICW (P<0.01). Overall adiposity may be determined by using body water compartments and body water compartments as simple, low-cost and quick techniques are more appreciate for estimating overall obesity than central obesity.
Determination of the effect of the interaction between Ghrelin and serotonin agonist (R)-8-OH-DPAT on the mean plasma concentrations of T3 & T4 in rat
Mozhdeh Mansouri,Homayoun Khazali
Physiology and Pharmacology , 2008,
Abstract: Introduction: Previous studies have shown that ghrelin inhibits the activity of Hypothalamus –Pituitary – Thyroid (H–P-T) axis. It is also proved that ghrelin increases appetite via Agouti Related Protein and neuropeptide Y pathway, decreases T3 & T4 secretion and inhibits serotonin release from hypothalamic synaptosomes. Serotonin may interact with ghrelin in control of thyroid hormones secretion. Thus, the goal of this study was to determine the influence of the interaction between ghrelin and serotonin agonist on thyroid hormones concentration. This is a suugestive mechanism to determine the effect of serotonin agonist in decreasing the effect of ghrelin. Methods: Twenty four male Wistar rats weighing 230-250 g were randomly divided into 3 groups. The groups respectively received 5 nmol ghrelin ,20 nmol serotonin agonist (R)-8-OH-DPAT or 5 nmol ghrelin with 20 nmol (R)-8-OH-DPAT in the volume of 5μl during 3 days via lateral cerebral ventricle. The blood samples were collected from one day before to one day after injections and brain slices were taken to ensure the place of the canulae is right. The plasma were analysed by Radio Immuno Assay technique to determine T3 and T4 concentrations. Results: The results of this experience showed that the (.i.c.v) injection of ghrelin and (R)-8-OH-DPAT respectively decreased and increased the mean plasma concentrations of thyroid hormones significantly (p<0.05), while the interaction of these two substances showed that (R)-8-OH-DPAT can decease the inhibitory effect of ghrelin on thyroid hormones concentration, but this effect is not statistically significant. (p<0.05) Conclusion: This study showed that ghrelin decreased mean plasma concentration of T3 & T4 significantly and serotonin agonist while injected with ghrelin , because of the stronger effect of ghrelin, could not significantly inhibit this effect of ghrelin. (p<0.05)
Six Decades of the Second Food Regime in Iran, the Trajectory of Iranian National Food Regime  [PDF]
Mozhdeh Babagoli, Satoshi Ikeda
Open Journal of Social Sciences (JSS) , 2019, DOI: 10.4236/jss.2019.76016
Abstract: Since the 1980s, international corporations have curtailed the autonomy of national states and have developed a new form of global food regime. Although the nouvelle regime promoted a new level of economic exploitation of the Global South, there are still some countries which resist the globalist corporations’ penetration into their economies. This paper argues that the Iranian economy, due to a variety of reasons which were not necessarily endogenous, such as international sanctions, could not have been conquered by corporations. The Iranian revolutionary regime which had come up with the slogans of “Achieving Self-Sufficiency” and “Standing against Global Imperialism,” stepped towards liberalization and privatization in less than ten years. However, the political sensitivity of food, as well as various forms of sanctions against Iran, did not provide the possibility of complete integration of Iranian food sector into the global free trade system. Even the IMF’s prescription of economic reform did not lead to much deregulation, and just expanded the quasi-state sector of the Iranian economy. Therefore, the national regime, which is an evolved form of the former food regime, still overshadows the agricultural economy of Iran. The recent post-deal era also does not seem to bring a serious threat to the Iranian national food regime.
Citrate capped superparamagnetic iron oxide nanoparticles used for hyperthermia therapy  [PDF]
Elham Cheraghipour, Sirus Javadpour, Ali Reza Mehdizadeh
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.512089
Abstract: Superparamagnetic magnetite nanoparticles (MNP) of about 10 nm were designed with proper physico-chemical characteristics by an economic, biocompatible chemical coprecipitation of Fe2+ and Fe3+ in an ammonia solution, for hyperthermia applications. Synthetic methodology has been developed to get a well dispersed and homogeneous aqueous suspension of MNPs. Citric acid was used to stabilize the magnetite particle suspension, it was anchored on the surface of freshly prepared MNPs by direct addition method. Carboxylic acid terminal group not only render the particles more water dispersible but also provides a site for further surface modification. The naked MNPs are often insufficient for their stability, hydrophilicity and further functionalization. To overcome these limitations, citric acid was conjugated on the surface of the MNPs. The microstructure and morphology of the nanoparticles were characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM), and the interaction between citric acid and MNPs were characterized by Fourier transform infrared spectroscopy (FTIR), whereas the magnetic properties were investigated by vibrating sample magnetometry (VSM). Magnetic measurement revealed that the saturation magnetization of the nanoparticles was 74 emu/g and the nanoparticles were superparamagnetic at room temperature. We also have analyzed the potential of these particles for hyperthermia by determination of the specific absorption rate, the temperature increase (ΔT) of the particles was 37oC. These ferrofluids with high self-heating capacity are a promising candidate for cancer hyperthermia treatment.
Study of Effect of Adaptive Histogram Equalization on Image Quality in Digital Preapical Image in Pre Apex Area
Mojdeh Mehdizadeh,Sepideh Dolatyar
Research Journal of Biological Sciences , 2012,
Abstract: Comparing direct digital radiographs before and after processing with Adaptive Histogram Equalization (AHE) in order to detect the effectiveness of this option on diagnostic ability of images in pre apex area. In this study, 28 digital radiographs were evaluated and were scored from 1-5 for three different anatomical areas by three dentists who were expert in reading digital radiographs. Then, we processed the images with adaptive histogram equalization. Each reading was first done on unprocessed radiograph (single view) and then re-done with image processed with adaptive histogram equalization displayed beside the unprocessed version (twin view). Histogram equalization of images by the way of increasing contrast were caused in increasing the diagnostic ability of lamina dura and root apex in maxilla and lamina dura, bone trabeculation and root apex in mandible. But, quality of diagnosing of bone trabeculation in maxilla was decreased by this method. Displaying a dental image processed with adaptive histogram equalization together with unprocessed image may enhance the subjectively evaluated image quality, thereby providing extra information for the dentist. The twin view procedure facilitates the discerning of root apex in preapical images with suboptimal quality.
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