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Search Results: 1 - 10 of 17009 matches for " Mostafa El-sayed Abdel-wanis "
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Preoperative Versus Postoperative Radiation Therapy in Patients with Soft Tissue Sarcomas
Mohamed Ibrahim El-sayed,Doaa Wadie Maximos,Mostafa El-sayed Abdel-wanis,Amen Hamdy Zaky
Cancer and Clinical Oncology , 2012, DOI: 10.5539/cco.v1n2p36
Abstract: Purpose: To evaluate treatment outcome and to determine whether or not the timing of radiotherapy (RT) was associated with any difference in disease relapse, survival, or incidence of complications in patients with soft tissue sarcomas (STS). Methods: The medical files of 63 patients with a primary, nonmetastatic, STS, treated with surgery and irradiation were evaluated. Data regarding tumor stage, grade, site, dosage and timing of radiotherapy, treatment complications, disease relapse, and disease-free (DFS) and overall survival (OAS) rates were analyzed. Results: The median follow up was 47 months (range; 5-66 months). Four-year OAS and DFS rates were 82.6% and 78.8% respectively. There were significant higher 4-year OAS (p = 0.024) and DFS (p = 0.011) rates in patients with stage I and II diseases than those in patients with stage III disease. On the other hand, there were no significant differences in 4-year OAS (p = 0.83, HR: 0.743, 95% CI: 0.165 to 3.345) and DFS (p = 0.64, HR: 0.74, 95% CI: 0.21 to 2.61) rates between preoperative and postoperative RT patients. Disease relapse for preoperative versus postoperative RT patients was not statistically different (p = 0.41). Wound complications were more frequent in preoperative RT patients (25%) compared to postoperative RT patients (8%) (p = 0.0566 chi-square). Conclusions: Preoperative irradiation has not a positive impact on survival or disease relapse rates, but is associated with high wound complication rate.
Feasibility of breast conservation after neoadjuvant taxene based chemotherapy in locally advanced breast cancer: a Prospective Phase I trial
Mohamed I El-Sayed, Doaa W Maximous, Mohamed A Aboziada, Mostafa E Abdel-Wanis, Nabiel NH Mikhail
Annals of Surgical Innovation and Research , 2010, DOI: 10.1186/1750-1164-4-5
Abstract: Forty five patients had stage IIB (except those with T2N1 disease) and stage IIIA were selected to 3 cycles taxane-based neoadjuvant chemotherapy. Patient who had tumours ≤5 cm underwent a tentative BCS while patients who had tumour size >5 cm underwent radical surgery. Negative margin is essential for BCS. Adjuvant chemotherapy and 3-D radiotherapy ± hormonal treatment were given to all patients.Thirty four patients had BCS. Response to chemotherapy was the only statistically significant factor which influences the BCS. Incidence of local recurrence was 5.9% for patients who had BCS at a median follow up 24 months.Breast conservation is feasible in selected cases of locally advanced, non metastatic cancer breast. We recommend that patients who have tumour size ≤4 cm after chemotherapy are the best candidates for BCS.Long-term survival is common among women with locally advanced breast cancer; therefore, quality of life issues become vitally important. For most women, loss of a breast is emotionally disturbing [1].The patient's response to preoperative chemotherapy is a powerful prognostic factor in predicting disease-free and overall survival from locally advanced breast cancer [2,3]. By assessing the response to preoperative chemotherapy, it is possible to select out a better prognosis group of patients who will have improved long-term survival and a low rate of local recurrence. Therefore, patients who respond to preoperative chemotherapy are often the best candidates for breast conservation, allowing for less disfigurement with preservation of function [3,4].Several studies have documented the feasibility and safety of breast conservation for locally advanced breast cancer after preoperative chemotherapy. Breast conservation is possible in 27% to 90% of patients after preoperative chemotherapy [4,5]. Local recurrence rates after breast conservation are low (5% - 10%) in patients who respond to preoperative chemotherapy [6,7].Our primary outcome was the evaluatio
Preoperative gemcitabine based chemo-radiotherapy in locally advanced non metastatic pancreatic adenocarcinoma
Doaa W Maximous, Mostafa E Abdel-Wanis, Mohammed I El-Sayed, Alaa A Abd-Elsayed
International Archives of Medicine , 2009, DOI: 10.1186/1755-7682-2-7
Abstract: From March 2006 to November 2007, 25 patients with locally advanced non metastatic pancreatic cancer were treated by preoperative gemcitabine based chemo-radiotherapy. The radiation dose was 54 Gray in 30 fractions over 6 weeks prescribed to the isocenter. Gemcitabine (300 mg/m2) was given through a 30 minute intravenous infusion. This was done 30 minutes before the radiation sitting on a weekly basis throughout the radiotherapy course.Approximately 6 weeks after the completion of chemo radiation, an evaluation was performed regarding tumour response and resectability as well as acute toxicity. Pancreaticoduodenectomy was performed for operable patients with surgical reconstruction.Patients who achieved complete resection (CR) numbered 2 (8%), while those achieving partial resection (PR) totalled 11 (44%); six of these patients were considered ro be operable. Thus Pancreaticoduodenectomy was performed on 8 patients (2 with CR and 6 with PR) with surgical reconstruction. Patients who had a stable disease numbered 4 (16%), and those with progressive diseases included a group of eight (32%). The postoperative 30 day mortality occurred only in one patient (12.5%). Acute toxicity of chemoradiation occurred in the form of grade I leucopoenia and thrombocytopenia. Hepatic toxicity, nausea, and vomiting were found in 8 patients (32%), 10 patients (40%) and 4 patients (16%), respectively. The postoperative 30 day mortality occurred only in 1 patient. Also, minor biliary leakage and leakage from gastrointestinal anaestomosis both occurred in a single patient. Out of the 8 patients who underwent radical surgical resection, only one developed local recurrence and simultaneous liver metastasis during the follow up period. The median survival of all patients was 12 months.Preoperative gemcitabine based chemoradiation might benefit patients with locally advanced non metastatic pancreatic cancer by increasing the resectability without significant acute toxicity.Almost 30% of patien
The Uncertainties of the Calculated Optical Basicity from the Optical Band Gap and the Refractive Index for Some Oxide Glass Systems
El-Sayed Mostafa
Journal of Applied Sciences , 2005,
Abstract: In this study, the uncertainties of the optical basicity calculation based on the optical band gap and the refractive index for two glass systems (K2O-Nb2O5-TeO2, B2O3-Na2O-TeO2), have been estimated. The results benefits are very important in the determination of the optical basicity of binary and ternary glass systems. It has been established that as in the binary glass systems, there is a general trend of increasing the oxide ion polarizability with decreasing the oxide optical band gap and increasing the refractive index of the glass samples. Also it has been found that the uncertainty of the optical basicity estimation is around ±5 to ±15%. Some tables have been reported to help us predict the method used to determine the optical basicity for a glass system accurately.
Realization of Metamaterial Zeroth-Order Resonators Based on MIM Capacitor
Mohamed M Mansour,El-Sayed M El-Rabaie,Abdel-Aziz T Shalaby,Mostafa A Elmala
International Journal of Nano Devices, Sensors and Systems , 2013, DOI: 10.11591/ij-nano.v2i1.1950
Abstract: A metamaterial Zeroth-Order Resonator (ZOR), based on Metal-Insulator-Metal (MIM) capacitor, constructed by two-layers substrate is presented. Compared to monolayer structure, the proposed structure achieves lower transmission frequency, compact dimensions and more freedom in the design process. The structure has been designed, fabricated and tested. The measured return loss, at 2 GHz operating frequency, is -22 dB and the unloaded Q factor is around 250
Elevated Temperatures Tensile Characteristics of Cast A356/Al2O3 Nanocomposites Fabricated Using a Combination of Rheocasting and Squeeze Casting Techniques  [PDF]
El-Sayed Youssef El-Kady, Tamer Samir Mahmoud, Mohamed Abdel-Aziz Sayed
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.25050
Abstract: In the present investigation, the tensile properties of A356/Al2O3 nanocomposites at both ambient and elevated temperatures were studied. The A356/Al2O3 nanocomposites were fabricated using a combination between the rheocasting and squeeze casting techniques. The A356 matrix alloy was reinforced with Al2O3 nanoparticulates having average sizes of 60 nm and 200 nm with different volume fractions up to 5 vol%. The results revealed that the A356/Al2O3 nanocomposites exhibited better mechanical properties than the A356 monolithic alloy. Such improvement in the mechanical properties was observed at both room and elevated temperatures up to 300°C. Increasing the volume fraction and/or reducing the size of Al2O3 nanoparticulates increase both the tensile and yield strengths of the nanocomposites.
Numerical Investigation of the Geometric Phase and Entropy Squeezing for a Two-Level System in the Presence of Decoherence Terms  [PDF]
Moustafa M. Salama, Ahmed O. Elnubi, Sayed Abdel-Khalek, Mohamed A. El-Sayed
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2013, DOI: 10.4236/jemaa.2013.59057
Abstract:

In this paper, we have presented the numerical investigation of the geometric phase and field entropy squeezing for a two-level system interacting with coherent field under decoherence effect during the time evolution. The effects of the initial state setting and atomic dissipation damping parameter on the evolution of the geometric phase and entropy squeezing have been examined. We have reported some new results related to the periodicity and regularity of geometric phase and entropy squeezing.

On the Electrical and Thermal Conductivities of Cast A356/Al2O3 Metal Matrix Nanocomposites  [PDF]
El-Sayed Youssef El-Kady, Tamer Samir Mahmoud, Ali Abdel-Aziz Ali
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.29159
Abstract: To assess the effect of the dispersion of Al2O3 nanoparticles into A356 Al alloy on both the electrical and thermal conductivities, A356/Al2O3 metal matrix nanocomposites (MMNCs) were fabricated using a combination of rheocasting and squeeze casting techniques. Two different sizes of Al2O3 nanoparticles were dispersed into the A356 Al alloy, typically, 60 and 200 nm with volume fractions up to 5 vol%. The effect of the nanoparticles size and volume fraction on the electrical and thermal conductivities was evaluated. The results revealed that the A356 monolithic alloy exhibited better electrical and thermal conductivities than the MMNCs. Increasing the nanoparticles size and/or the volume fraction reduces both the thermal and electrical conductivities of the MMNCs. The maximum reduction percent in the thermal and electrical conductivities, according to the A356 monolithic alloy, were about 47% and 38%, respectively. Such percentages were exhibited by A356/Al2O3MMNCs containing 5 vol% of nanoparticles having 60 and 200 nm, respectively.
An augmented Lagrangian SQP method for solving some special class of nonlinear semi-definite programming problems
Mostafa, El-Sayed M.E.;
Computational & Applied Mathematics , 2005,
Abstract: in this paper, we consider a special class of nonlinear semi-definite programming problems that represents the fixed order h2/h¥ synthesis problem. an augmented lagrangian sequential quadratic programming method combined with a trust region globalization strategy is described, taking advantage of the problem structure and using inexact computations. some numerical examples that illustrate the performance of the method are given.
The Importance of Using Some Glass Systems as Standard in Transmission Spectrophotometry in the Visible and Ultraviolet Regions
El-Sayed Mostafa,Moenis Azooz
Journal of Applied Sciences , 2006,
Abstract: This study deals with the possibility of using a system of glass borates as a former, Na2O and pbO as modifiers doped with Cu++ 0.1 wt.% , 3 wt.% Er2O3 , 3 wt.% H2O3 and 0.2 wt.% H2O3 chromophors in the system, as a standard filter in the visible, Uv and IR regions. In an instrument as complex as a spectrophotometer there are many sources of error. Because of this it is useful to have available standard materials whose spectral transmittance are known accurately. Periodic measurements of such standards provide a useful indication of whether a spectrophotometer is producing accurate results. If the spectral transmittance functions of these standards are chosen suitably, the measurements can provide diagnostic information to indicate what type of error is occurring. The results of the spectral transmittance and optical band gap show that the suggested glass is stable for environmental conditions, so we can consider that system as good as commercial standard.
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