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Search Results: 1 - 10 of 463785 matches for " Monika A. Czudowska "
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Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma
Leonieke M. E. van Koolwijk equal contributor,Wishal D. Ramdas equal contributor,M. Kamran Ikram,Nomdo M. Jansonius,Francesca Pasutto,Pirro G. Hysi,Stuart Macgregor,Sarah F. Janssen,Alex W. Hewitt,Ananth C. Viswanathan,Jacoline B. ten Brink,S. Mohsen Hosseini,Najaf Amin,Dominiek D. G. Despriet,Jacqueline J. M. Willemse-Assink,Rogier Kramer,Fernando Rivadeneira,Maksim Struchalin,Yurii S. Aulchenko,Nicole Weisschuh,Matthias Zenkel,Christian Y. Mardin,Eugen Gramer,Ulrich Welge-Lüssen,Grant W. Montgomery,Francis Carbonaro,Terri L. Young,The DCCT/EDIC Research Group,Céline Bellenguez,Peter McGuffin,Paul J. Foster,Fotis Topouzis,Paul Mitchell,Jie Jin Wang,Tien Y. Wong,Monika A. Czudowska,Albert Hofman,Andre G. Uitterlinden,Roger C. W. Wolfs,Paulus T. V. M. de Jong,Ben A. Oostra,Andrew D. Paterson,Wellcome Trust Case Control Consortium 2,David A. Mackey,Arthur A. B. Bergen,André Reis,Christopher J. Hammond,Johannes R. Vingerling,Hans G. Lemij,Caroline C. W. Klaver,Cornelia M. van Duijn
PLOS Genetics , 2012, DOI: 10.1371/journal.pgen.1002611
Abstract: Intraocular pressure (IOP) is a highly heritable risk factor for primary open-angle glaucoma and is the only target for current glaucoma therapy. The genetic factors which determine IOP are largely unknown. We performed a genome-wide association study for IOP in 11,972 participants from 4 independent population-based studies in The Netherlands. We replicated our findings in 7,482 participants from 4 additional cohorts from the UK, Australia, Canada, and the Wellcome Trust Case-Control Consortium 2/Blue Mountains Eye Study. IOP was significantly associated with rs11656696, located in GAS7 at 17p13.1 (p = 1.4×10?8), and with rs7555523, located in TMCO1 at 1q24.1 (p = 1.6×10?8). In a meta-analysis of 4 case-control studies (total N = 1,432 glaucoma cases), both variants also showed evidence for association with glaucoma (p = 2.4×10?2 for rs11656696 and p = 9.1×10?4 for rs7555523). GAS7 and TMCO1 are highly expressed in the ciliary body and trabecular meshwork as well as in the lamina cribrosa, optic nerve, and retina. Both genes functionally interact with known glaucoma disease genes. These data suggest that we have identified two clinically relevant genes involved in IOP regulation.
Inhibiting Effect of Tetra-n-Butylammonium Iodide on the Corrosion of Mild Steel in Acidic Medium
,Monika; Siddique,W.A.;
Portugaliae Electrochimica Acta , 2007,
Abstract: the inhibition effect of tetra-n-butylammonium iodide (tbai) on mild steel in 1 n h2so4 has been studied by using weight loss, electrochemical polarization, fourier transform infrared (ftir) and scanning electron microscopic (sem) techniques. it has been concluded that the percentage inhibition increases with increasing the concentration of the inhibitor. the adsorption of tbai on mild steel surface in 1 n h2so4 obeys langmuir adsorption isotherm; surface analysis and ir studies are also carried out to establish the mechanism of corrosion inhibition.
Inhibiting Effect of Tetra-n-Butylammonium Iodide on the Corrosion of Mild Steel in Acidic Medium
Monika,W.A. Siddique
Portugaliae Electrochimica Acta , 2007,
Abstract: The inhibition effect of tetra-N-butylammonium iodide (TBAI) on mild steel in 1 N H2SO4 has been studied by using weight loss, electrochemical polarization, Fourier Transform Infrared (FTIR) and scanning electron microscopic (SEM) techniques. It has been concluded that the percentage inhibition increases with increasing the concentration of the inhibitor. The adsorption of TBAI on mild steel surface in 1 N H2SO4 obeys Langmuir adsorption isotherm; surface analysis and IR studies are also carried out to establish the mechanism of corrosion inhibition.
Synthesis, Structural, and Biological Studies of Some Schiff Bases and Their Metal Complexes
A. P. Mishra,Monika Soni
Metal-Based Drugs , 2008, DOI: 10.1155/2008/875410
Abstract: New bidentate or tridentate Schiff bases and their VO(II) and Co(II) complexes formed by the condensation of methyl isobutyl ketone with nicotinamide (mna)/2-amino-4-chlorophenol (map) and 2-hydroxy acetophenone with nicotinamide (han)/isoniazide (hai). Physicochemical characterization has been carried out to determine the structure of the complexes. The FAB mass and thermal data show degradation pattern of the complexes. XRD analysis reveals that all the studied complexes crystallize as tetragonal crystal system. Some of the complexes have been screened for their antimicrobial activity by the well diffusion technique using DMSO as solvent on different species of pathogenic bacteria/fungi, that is, E. coli, S. aureus, S. fecalis, A. niger, T. polysporum, and their antimicrobial potency have been discussed. It has been found that all the complexes are antimicrobially active and show higher activity than the free ligand. Metal chelation affects significantly the antimicrobial/bioactive behavior of the organic ligands.
Journey from the Heart of Darkness to the Heart of Sadness: Fiction v/s Reality
Yousof A. Qasaimeh,Monika Joshi
International Journal of Psychological Studies , 2009, DOI: 10.5539/ijps.v1n1p42
Abstract: The purpose of this study is to perceive the give – and – take between art and real life conditions. It presents information on the writing of the novel Heart of Darkness by Joseph Conrad whose continental experience and familiarity with the imperial milieu in the east and Africa rendered him capable of bringing much greater knowledge of real politic into literary work more than any one else. It seems fruitful to see how the authors deal with the gap between how things could or should be in a given society, and how they really are. International politics is devoid of moral values as can be seen in the case of Congo in Heart of Darkness (a fictional situation) and in the present Iraqi situation (a real- life situation). In Heart of Darkness there is a suggestion that the exploited will some day, sooner or later, rise in revolt against the exploitation of the foreign rule. Can oppressed nations like Congo and Iraq hope to conclude this tiresome journey in the near future and set out a fresh on new journey, perhaps one into the Heart of Happiness? The answer to this question remains unknown at the present time. In spite of this, people of these nations should be optimize, keeping in mind that it is always darkest before the dawn, and that Stars shine out the most brilliantly through dark clouds.
Methods for the Study of Transverse Momentum Differential Correlations
Monika Sharma,Claude A. Pruneau
Physics , 2008, DOI: 10.1103/PhysRevC.79.024905
Abstract: We introduce and compare three differential correlation functions for the study of transverse momentum correlation in $p+p$ and $A+A$ collisions. These consist of {\it inclusive}, {\it event-wise} and a differential version of the correlation measure $\tilde C$ introduced by Gavin \cite{Gavin} for experimental study of the viscosity per unit entropy of the matter produced in $A+A$ collisions. We study the quantitative difference between the three observables on the basis of PYTHIA simulations of $p+p$ collisions and $A+A$ collisions consisting of an arbitrary superposition of $p+p$ collision events at $\sqrt{s} = $200 GeV. We observe that {\it inclusive} and {\it event-wise} correlation functions are remarkably identical to each other where as the observable $\tilde C$ differs from the two. We study the robustness and efficiency dependencies of these observables based on truncated Taylor expansions in efficiency in $p+p$ collisions and on the basis of Monte Carlo simulation using an adhoc detector efficiency parameterization. We find that all the three observables are essentially independent of detector efficiency. We additionally study the scaling of the correlation measures and find all the observables exhibit an approximate $1/N$ dependence of the number of participants ({\it N}) in $A+A$ collisions. Finally, we study the impact of flow-like anisotropy on the {\it inclusive} correlation function and find flow imparts azimuthal modulations similar to those observed with two-particle densities.
The Effect of Different Movement Exercises on Cognitive and Motor Abilities  [PDF]
Monika Thomas
Advances in Physical Education (APE) , 2012, DOI: 10.4236/ape.2012.24030
Abstract: The influence of physical activity on motor and cognitive performance has been approved in several studies. However, it is still unclear which functions are affected, and why. It also remains unknown what type of physical training is best suitable. The present study focuses on special movement aspects based on the Brain Gym? program. Four groups of subjects (n = 64) participated in two experiments with pre-post intervention design. In experiment 1 two groups of subjects were exposed to a sensorimotor adaptation study design by executing center out pointing movements under distorted visual feedback conditions with their dominant and non-dominant arm to test for intermanual transfer (IMT) as pre- and posttest. The intervention in both groups consisted of specified movement exercises with the right and left extremities: participants of Experimental group executed movements crossing the body midline and participants of Control group movements without crossing the body midline. Results showed a decreased retention of adaptation but larger IMT for Experimental group during posttest. We conclude that movements crossing the body midline impede retention but enhance IMT of sensorimotor adaptation. A potential relationship to an improvement of communication between the cerebral hemispheres evoked by the movement exercises crossing the body midline is rather speculative. In experiment 2 two groups were exposed to the d2-test measuring concentration and attention and a dice-test testing for visual-spatial abilities as pre- and posttest. The interventions were similar to experiment 1. Results yielded no differences between groups such that different effects of both interventions could not have been shown.
Two Blind Adaptive Equalizers Connected in Series for Equalization Performance Improvement  [PDF]
Monika Pinchas
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.41008
Abstract:

A variable step-size parameter is usually used to accelerate the convergence speed of a blind adaptive equalizer with N1 + N2 -1 coefficients where N1 and N2 are odd values. In this paper we show that improved equalization performance is achieved when using two blind adaptive equalizers connected in series where the first and second blind adaptive equalizer have N1 and N2 coefficients respectively compared with the case where a single blind adaptive equalizer is applied with N1 + N2 -1 coefficients. It should be pointed out that the same algorithm (cost function) is used for updating the filter taps for the different equalizers and that a fixed step-size parameter is used. Simulation results show that for the low signal to noise ratio (SNR) environment and for the case where the convergence speed is slow due to the channel characteristics, the new method has a faster convergence speed with a factor of approximately two while leaving the system with approximately the same or lower residual intersymbol interference (ISI).

Under What Condition Do We Get Improved Equalization Performance in the Residual ISI with Non-Biased Input Signals Compared with the Biased Version  [PDF]
Monika Pinchas
Journal of Signal and Information Processing (JSIP) , 2015, DOI: 10.4236/jsip.2015.62008
Abstract: Recently, closed-form approximated expressions were obtained for the residual Inter Symbol Interference (ISI) obtained by blind adaptive equalizers for the biased as well as for the non-biased input case in a noisy environment. But, up to now it is unclear under what condition improved equalization performance is obtained in the residual ISI point of view with the non-biased case compared with the biased version. In this paper, we present for the real and two independent quadrature carrier case a closed-form approximated expression for the difference in the residual ISI obtained by blind adaptive equalizers with biased input signals compared with the non-biased case. Based on this expression, we show under what condition improved equalization performance is obtained from the residual ISI point of view for the non-biased case compared with the biased version.
Convolutional Noise Analysis via Large Deviation Technique  [PDF]
Monika Pinchas
Journal of Signal and Information Processing (JSIP) , 2015, DOI: 10.4236/jsip.2015.64024
Abstract: Due to non-ideal coefficients of the adaptive equalizer used in the system, a convolutional noise arises at the output of the deconvolutional process in addition to the source input. A higher convolutional noise may make the recovering process of the source signal more difficult or in other cases even impossible. In this paper we deal with the fluctuations of the arithmetic average (sample mean) of the real part of consecutive convolutional noises which deviate from the mean of order higher than the typical fluctuations. Typical fluctuations are those fluctuations that fluctuate near the mean, while the other fluctuations that deviate from the mean of order higher than the typical ones are considered as rare events. Via the large deviation theory, we obtain a closed-form approximated expression for the amount of deviation from the mean of those fluctuations considered as rare events as a function of the system’s parameters (step-size parameter, equalizer’s tap length, SNR, input signal statistics, characteristics of the chosen equalizer and channel power), for a pre-given probability that these events may occur.
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