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Search Results: 1 - 10 of 4065 matches for " Monica Jha "
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Document Clustering using K-Medoids
Monica Jha
Computer Science , 2015,
Abstract: People are always in search of matters for which they are prone to use internet, but again it has huge assemblage of data due to which it becomes difficult for the reader to get the most accurate data. To make it easier for people to gather accurate data, similar information has to be clustered at one place. There are many algorithms used for clustering of relevant information in one platform. In this paper, K-Medoids clustering algorithm has been employed for formation of clusters which is further used for document summarization.
Anastrozole Use in Early Stage Breast Cancer of Post-Menopausal Women
Monica Milani,Gautam Jha,David A. Potter
Clinical Medicine : Therapeutics , 2009,
Abstract: The majority of breast cancers express the estrogen receptor and depend on estradiol (E2) for their growth. Hormonal therapy aims at depriving estrogen signaling either by using selective estrogen receptor modulators (SERM) - that interfere with the binding of E2 to its receptor (ER) - or aromatase inhibitors (AI) - that block the aromatase-dependent synthesis of E2. While SERMs are recommended for both pre- and post-menopausal patients, AIs are indicated only for post-menopausal patients. For the past 20 years, the SERM tamoxifen has been considered the “gold standard” for the treatment of hormone receptor positive breast cancers. However, tamoxifen’s role is now challenged by third generation AIs, such as anastrozole, which exhibit greater efficacy in the adjuvant setting in several recently reported trials. This review will focus on anastrozole’s mechanism of action, dosing, pharmacology, pharmacokinetics, and clinical applications. It will briefly discuss the clinical trials that determined anastrozole’s efficacy in the treatment of advanced breast cancer (ABC) and in the neo-adjuvant setting. Finally, it will present the clinical trials that established anastrozole as a frontline agent in the treatment of post-menopausal women with hormone receptor positive early breast cancer.
Document Clustering using K-Means and K-Medoids
Rakesh Chandra Balabantaray,Chandrali Sarma,Monica Jha
Computer Science , 2015,
Abstract: With the huge upsurge of information in day-to-days life, it has become difficult to assemble relevant information in nick of time. But people, always are in dearth of time, they need everything quick. Hence clustering was introduced to gather the relevant information in a cluster. There are several algorithms for clustering information out of which in this paper, we accomplish K-means and K-Medoids clustering algorithm and a comparison is carried out to find which algorithm is best for clustering. On the best clusters formed, document summarization is executed based on sentence weight to focus on key point of the whole document, which makes it easier for people to ascertain the information they want and thus read only those documents which is relevant in their point of view.
Primary tubercular liver abscess in an immunocompetent adult: a case report
CP Baveja, Vidyanidhi Gumma, Monica Chaudhary, Himanshu Jha
Journal of Medical Case Reports , 2009, DOI: 10.1186/1752-1947-3-78
Abstract: A 30-year-old man, of Asian origin, developed a hepatic tubercular abscess which was not associated with any pulmonary or gastrointestinal tract foci of tuberculosis. An ultrasonogram of the abdomen showed an abscess in the right lobe of his liver which was initially diagnosed as an amoebic liver abscess. Subsequently, the pus from the lesion yielded Mycobacterium tuberculosis using the BACTEC TB 460 instrument and Mycobacterium tuberculosis deoxyribonucleic acid by polymerase chain reaction. The patient was started on systemic antitubercular therapy to which he responded favorably.This report emphasizes the fact that, although a tuberculous liver abscess is a very rare entity, it should be included in the differential diagnosis of unknown hepatic mass lesions.Though hepatic tuberculosis is not a rare disease entity, tubercular liver abscess (TLA) is extremely rare even in a country where tuberculosis is an alarming public health problem. It is usually associated with foci of infection either in the lung and/or gastrointestinal (GI) tract [1], or with an immunocompromised state. An isolated or primary TLA with no evidence of tuberculosis elsewhere is even rarer. The diagnosis is difficult in most instances and is frequently confused with hepatoma, pyogenic liver abscess or amoebic liver abscess [2-4]. The rarity of this clinical entity prompted us to present this case which involves an immunocompetent adult with an isolated hepatic tubercular abscess and with no foci of infection in the lungs or GI tract.A 30-year-old man of Asian origin, presented to the surgery outpatient department (OPD) with non-radiating pain in the right hypochondrium and epigastrium associated with vomiting, intermittent fever with chills and rigors for 10 days. The onset was gradual with increasing weakness and deterioration of his general health. The patient was undergoing follow-up for a liver abscess (right lobe) which was diagnosed previously as an amoebic liver abscess (ALA) based on a
Rating Curve Estimation of Surface Water Quality Data Using LOADEST  [PDF]
Bhasker Jha, Manoj Kumar Jha
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.48099
Abstract:

Measurement of the nutrient concentrations in the stream is usually done on weekly, biweekly or monthly basis due to limited resources. There is need to estimate concentration and loads during the period when no data is available. The objectives of this study were to test the performance of a suite of regression models in predicting continuous water quality loading data and to determine systematic biases in the prediction. This study used the LOADEST model which includes several predefined regression models that specify the model form and complexity. Water quality data primarily nitrogen and phosphorus from five monitoring stations in the Neuse River Basin in North Carolina, USA were used in the development and analyses of rating curves. We found that LOADEST performed generally well in predicting loads and observation trends with general tendency/bias towards overestimation. Estimated Total Nitrogen (TN) varied from observation (“true” load) by -1% to 9%, but for the Total Phosphorus (TP) it ranged from -2% to 27%. Statistical evaluation using R2, Nash-Sutcliff Efficiency (NSE) and Partial Load Factor (PLF) showed a strong correlation in prediction.

Epistemological and Pedagogical Concerns of Constructionism: Relating to the Educational Practices  [PDF]
Arbind K. Jha
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.32027
Abstract: Today’s world may be defined as the world of constructs and all constructs can be categorised into either Mental or Social. Social constructs are creative urge and constructs of Constructionists. Constructionists, focus on knowledge as power, believing that “cultural specifications” exert a real influence on people’s lives and takes a stand on the subjugating effect of discourses. In the case of education, perhaps the pivotal concept is that of knowledge itself. Constructionists assert that knowledge is not only constructed by an individual’s interaction with his/her own world (or experiences) but also co-created by his/her interaction with other individuals within a specific social community. This implies that both cognitive and social processes are involved in knowledge construction and expansion through the process of reflecting on and sharing their own experiences and others’ experiences or ideas as well. Constructionism is also a theory about the pedagogical value of active learning, in a practice that includes a teaching model of mediation as opposed to instruction. Given the socio-historical nature of knowledge, social constructionist curricular practices therefore centre on the collective construction and transmission of meaning, learning and knowledge in recognition that they are shaped by the historic conventions of culture and language. The primary educational challenge of the present century is to replace the traditional focus on the individual student with concerted investments in relational process. It emphasizes on from isolated to relational rationality and from dead curricula to cultural curricula where there is no walls of the classroom as an artificial barrier between educational and cultural processes. This paper studied the Constructionism theory and attempted to interrogate and develop the theoretical and practical propositions of how the epistemological and pedagogical concerns of Constructionism relate to the concepts and practices of education in contemporary world and more specifically how the implementation of Constructionist perspective will bring about desirable changes.
Plants: The Future Pharmaceutical Factory  [PDF]
Bipradut Sil, Sumita Jha
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.53044
Abstract:

The main objective of this study was to identify prospects, advantages and challenges of plant molecular farming. Plant-made pharmaceuticals (PMPs) and plant made vaccines (PMVs) were intended to be used for human consumption. A broad range of plants, including crops, vegetables and fruits have been investigated for their applicability in production of pharmaceuticals over the last two decades. At present, mainly maize, rice, tobacco and safflower are used in open field production. Contained bioreactor-type systems focus on moss, algae and plant organ culture. Expression systems include stable transformation of plant genomesboth nuclear and plastid, which are also used in the generation of genetically modified crops, plant-viruses and transient expressions. Each expression system (production platform) offers different advantages and disadvantages. Production platform choice is perceptive and depends on a broad range of criterion. This study is based on literature reviews, document analysis and internet database browsing.


Trace of Positive Integer Power of Real 2 × 2 Matrices  [PDF]
Jagdish Pahade, Manoj Jha
Advances in Linear Algebra & Matrix Theory (ALAMT) , 2015, DOI: 10.4236/alamt.2015.54015
Abstract: The purpose of this paper is to discuss the theorems for the trace of any positive integer power of 2 × 2 real matrix. We obtain a new formula to compute trace of any positive integer power of 2 × 2 real matrix A, in the terms of Trace of A (TrA) and Determinant of A (DetA), which are based on definition of trace of matrix and multiplication of the matrixn times, where n is positive integer and this formula gives some corollary for TrAn when TrA or DetA are zero.
Cultural Identity and Human Rights: Minority Claims, Ethnic Identity and Group Rights  [PDF]
Dhruv Pande, Munmun Jha
Open Journal of Political Science (OJPS) , 2016, DOI: 10.4236/ojps.2016.64032
Abstract: This paper explores the relationship between cultural identity and human rights in the light of the dynamics of identity formation, based on the immediate external culture of any multicultural society. The objective of this study is to analyze the relationship between culture, identity and rights, which broadens the parameter of the existing dimension of human rights, using secondary sources to review the literature. It argues that these dynamics are marked by a number of factors and components featuring the group, community and individual rights. This prepares grounds for a wider, inclusionary and horizontal understanding of the Human Rights dimension and paradigms, not only in a multicultural society but also in a democratic nation- state which is significantly marked by minority rights and ethnic identity claims. Thus through a critical approach and a post-colonial perspective, this paper shows how this specific and particular dynamics of cultural identity casts an effect on the theory and practice of normative political theory and trajectories. The paper concludes that the Human Rights inherently invoke a challenge in the analysis of identity-formation and cultural heterogeneity dynamics, which are significant in the contemporary global democratic politics.
Narrative Texts in Narrative Inquiry: Interpretive Voices to Better Understand Experiences in Given Space and Time  [PDF]
Sudhir Kumar Jha
Open Journal of Leadership (OJL) , 2018, DOI: 10.4236/ojl.2018.74014
Abstract: Narrative inquiry has often been regarded as a methodology evolved through human cultures of storytelling. Oftentimes, researchers espousing narrative inquiry face with the challenges of integrating meaning and perspectives into narrative texts. One group of scholars argues that narrative texts themselves are interpretations so a separate analysis is not needed. Other group goes on in favor of separating narratives from interpretation. In this context, based on my PhD field experiences with narrative inquiry on team leadership experiences of “larger size” private school principals of Kathmandu, Nepal, here I argue how narrative texts become interpretive voices open to many interpretations; and therefore, so as to make better understanding of the narratives, it is the role of researcher to make perspectival analysis of the field texts, position them to the given time and space of temporality, sociality, and place (Connelly & Clandinin, 2016) and share the researcher’s standpoints with the readers.
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