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Search Results: 1 - 10 of 3219 matches for " Monica Braghetto "
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Posibles impactos de la reforma de salud en la práctica quirúrgica: possible impacts on the surgical practice Health reform
Revista Chilena de Cirugía , 2006,
Revista Chilena de Cirugía , 2007,
Recombinant Chromosome 4 from a Familial Pericentric Inversion: Prenatal and Adulthood Wolf-Hirschhorn Phenotypes
Francesca Malvestiti,Francesco Benedicenti,Simona De Toffol,Sara Chinetti,Adelheid H?ller,Beatrice Grimi,Gertrud Fichtel,Monica Braghetto,Cristina Agrati,Eleonora Bonaparte,Federico Maggi,Giuseppe Simoni,Francesca Romana Grati
Case Reports in Genetics , 2013, DOI: 10.1155/2013/306098
Abstract: Pericentric inversion of chromosome 4 can give rise to recombinant chromosomes by duplication or deletion of 4p. We report on a familial case of Wolf-Hirschhorn Syndrome characterized by GTG-banding karyotypes, FISH, and array CGH analysis, caused by a recombinant chromosome 4 with terminal 4p16.3 deletion and terminal 4q35.2 duplication. This is an aneusomy due to a recombination which occurred during the meiosis of heterozygote carrier of cryptic pericentric inversion. We also describe the adulthood and prenatal phenotypes associated with the recombinant chromosome 4. 1. Introduction Wolf-Hirschhorn Syndrome (WHS) results from partial deletion of the distal short arm of chromosome 4 (4p16.3). The clinical features are variable, with increasing severity depending on the extent of the deletion, although the minimal diagnostic criteria should include the association of typical facial appearance, growth delay, mental retardation, and seizures [1]. Considering that small and large 4p16.3 deletions are associated with mild and severe WHS phenotype, respectively, Zollino et al. [1] have suggested a WHS classification in three categories based on the clinical presentation, all sharing the minimal diagnostic criteria: “mild” form (deletions < 3.5?Mb) refers to patients with a mild mental retardation (MR), possible fluent language, and usually independent walking by the age of 2-3 years; “classical” form (deletions 5–18?Mb) is characterized by major malformations, severe psychomotor delay (PMD), delay or absence of speech, and late walking; “severe” one (deletions > 22–25?Mb) has severe PMD and MR, facial anomalies, severe scoliosis, and psychotic behaviour. At a molecular level, two WHS critical regions (WHSCRs) have been identified: the WHSCR region, which is 165?Kb in size and it is located at about 2?Mb from the telomere between the markers D4S166 and D4S3327 [2], and the WHSCR-2 region which embraces a 300–600?Kb interval between the loci D4S3327 and D4S168 and it is mapped distal to WHSCR at about 1,9?Mb from the telomere [1]. Most of the 4p16 deletions involved in WHS occur de novo, but in 10%–15% of cases the derivative chromosome 4 originate from chromosomal rearrangements in one of the parents. Four different rearrangements are reported [1]: (1) isolated 4p deletion (70% of patients); (2) unbalanced translocation (22%); (3) inverted duplication associated with terminal 4p deletion (6%); (4) recombinant chromosome 4, rec(4), consisting of unbalanced pericentric inversion with a large 4q segment duplicated on the deleted 4p (2%). Herein we describe a
Correspondence Analysis on a Space-Time Data Set for Multiple Environmental Variables  [PDF]
Palma Monica
International Journal of Geosciences (IJG) , 2015, DOI: 10.4236/ijg.2015.610090
Abstract: Applications of the multivariate technique called correspondence analysis for environmental studies are relatively new and are limited to spatial multivariate data set. In this paper, a procedure of applying correspondence analysis to a large space-time data set for multiple environmental variables is shown. In particular, nitrogen dioxide and carbon monoxide hourly concentrations measured during January 1999 at several monitored stations in a district of Northern Italy are analyzed. The procedure consists in transforming the continuous variables into categorical ones by the means of appropriate indicator variables, generating special contingency tables and applying correspondence analysis. The use of this classical multivariate technique allows the identification of important relationships among pollution levels and monitoring stations and/or relationships among pollution levels and observation times.
Relación paciente-médico: Una alianza que fomenta la calidad Relation patient-doctor and quality of the attention
Revista Chilena de Cirugía , 2007,
Restrictive bariatric surgery techniques: evolution and current trends
Maher Musleh,Katya Carrillo,Italo Braghetto
Medwave , 2012,
Abstract: Bariatric surgery has proved to be more effective than medical therapy in the treatment for obesity. Multiple techniques have been described and can be divided into three main groups: Restrictive surgery, where the main objective is to decrease the volume of caloric intake; malabsortive surgery, where a portion of the absortive circuit is bypassed and thus limiting the caloric absortion; and a combination of both. Among the restrictive techniques, gastroplasty was one of the first procedures described. First horizontal gastroplasty and then vertical banded gastroplasty showed good short-term results but with poor long-term outcomes. These techniques have been gradually abandoned. Adjustable gastric banding is a minimally invasive technique and has the advantage of being reversible. Weight loss is adequate, but less effective than gastric bypass. Postoperative complications are low at short-term, but increase per year at long-term follow-up. Sleeve gastrectomy is an effective weight loss procedure that can be performed safely as a first stage or primary procedure. This results in excellent weight loss and co-morbidity reduction that exceeds, or is comparable to, that of other accepted bariatric procedures. Gastric plicature is a relatively new procedure and has reported good short-term outcomes in weight loss with few short-term complications. However, long-term outcomes are yet to be demonstrated.
Effect of Pixellization on Efficiency and Stability of MEH-PPV Based Polymer Light-Emitting Diodes  [PDF]
Ranbir Singh, Monica Katiyar
Journal of Encapsulation and Adsorption Sciences (JEAS) , 2012, DOI: 10.4236/jeas.2012.21002
Abstract: Organic light-emitting diodes are generally depicted as sequential deposition of active layers and electrodes onto a substrate, but commercial devices are fabricated using pixellization technique, where an insulator layer is introduced between the indium tin oxide and organic layer to define the area of the active device. Here, we have inserted a layer of photoresist (thickness ~ 200 nm) at the edge of patterned anode (indium tin oxide) and between the anode and hole transport layer (Poly 3, 4-ethylenedioxythiophene poly styrenesulfonate) to examine its effect on the leakage current of organic light-emitting diode and on the electron-hole recombination ratio in the emission area, as a result increasing the luminance efficiency. Current leakage causes the loss of charges, which adversely affects the recombination of electrons and holes in the emitting zone and results in poorer luminance efficiency. In this paper, we report the effect of pixellization on current density-voltage, luminescence-voltage and degradation behavior of single layer Poly[2-methoxy-5-(2’-ethylhexyloxy)-1, phenylene vinylene] based organic light-emitting diodes. Devices with isolation layer have 30% higher external electroluminescence quantum efficiency and reduced device degradation in comparison to without isolation layer.
Critical Factors in Managing Relationally Demanding Jobs, in Care for Very Ill and/or Dying Patients: A Phenomenological Study among Public Hospital Nurses  [PDF]
Asgerdur Bjarnadottir, Monica Lillefjell
Open Journal of Nursing (OJN) , 2015, DOI: 10.4236/ojn.2015.51007
Abstract: Background: Workload, interpersonal relationships, professional conflict and the emotional cost of providing care are potential sources of stress and burnout among nurses. Based on experiences of hospital nurses, this paper aims to identify critical factors for nurses in managing relationally demanding situations in care for very ill and/or dying patients. Methods: In-depth interviews were carried out with six nurses, working in a medium-sized hospital in Norway. The interviews were analysed using an interpretative phenomenological analysis. Results: The lack of identification with the core aspect of the job, relational contact with patients and relatives, and external motivation were found as potential barriers for managing relationally demanding jobs. The results also indicate that the nurses’ experiences of symptoms of burnout can be a result of demands that exceeded the nurses’ resources. A match between personal capacity and demands, mutual support among colleagues and leadership support, and contextual factors are critical to prevent the negative process of burnout. Conclusion: The results underscore the importance of an early response to employees who are beginning to struggle at work and the relevance of a true match between personal capacity and job demands. Moreover support among colleagues and leadership seems critical to prevent a negative process of burnout and help to manage relationally demanding jobs.
Thin Film Encapsulation at Low Temperature Using Combination of Inorganic Dyad Layers and Spray Coated Organic Layer  [PDF]
Sandeep Kumar, Monica Katiyar
Journal of Encapsulation and Adsorption Sciences (JEAS) , 2017, DOI: 10.4236/jeas.2017.74011
Abstract: Organic devices have many advantages such as low material consumption and low energy requirements, but they have serious issues regarding long term stability. Hence we need to develop a barrier film which solves this problem. Initially, the organic devices were fabricated on glass and were encapsulated using glass and epoxy (as sealant). Gradually there was a need to shift on to flexible substrates which required encapsulation to be flexible as well. Therefore, the motivation of the work is to develop thin film encapsulation that can be made flexible. The low temperature PECVD grown films of SiOx and SiNxwere used as the barrier film. Alternate inorganic layers (2-dyads) provided barrier of ~10-2 g/m2 day and increasing the number of dyads to five improved the water vapor transmission rate (WVTR) only by one order of magnitude. However, introducing organic layers in this structure resulted in WVTR value of order 10-5 g/m2 day. The organic layers were deposited by spray technique.
Reconstitui o do trato digestivo após falha de esofagogastro ou esofagocolo anastomose Digestive tract reconstitution after failed esophago-gastro or esophago-coloanastomosis
Italo Braghetto,Gonzalo Cardemil,Attila Csendes,Aliro Venturelli
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S?o Paulo) , 2013,
Abstract: RACIONAL: Disfagia grave ou mesmo afagia pode ocorrer após esofagectomia secundária à necrose do órg o ascendido com estenose severa ou separa o completa dos cotos. Ruptura catastrófica esofágica ou gástrica impulsiona a decis o de "desconectar" o es fago, a fim de evitar graves complica es sépticas. As opera es utilizadas para restabelecer a descontinuidade do es fago n o s o padronizadas e reopera es para restabelecimento do transito digestivo superior s o um verdadeiro desafio. MéTODOS: Este é estudo retrospectivo da experiência dos autores durante 17 anos incluindo 18 pacientes, 14 previamente submetidos à esofagectomia e quatro esofagogastrectomia. Eles foram operados com o fim de restabelecer o trato digestivo superior. RESULTADOS: Refazer esofagogastro anastomose foi possível em 12 pacientes, 10 por meio da abordagem cervical e combinando esternotomia em quatro, a fim de realizar a nova anastomose. Em cinco pacientes esofagocolo anastomose foi novamente realizada. Interposi o de enxerto livre de jejuno foi realizada em um paciente. As complica es ocorreram em 10 pacientes (55,5%): deiscência anastomótica em três, estenose em quatro, condrite esternal em dois e abscesso cervical em um. N o se observou mortalidade. CONCLUS O: Existem diferentes op es cirúrgicas para o tratamento desta situa o clínica difícil e arriscada; deve ser tratada com procedimentos adaptados de acordo com o segmento anat mico disponível para ser usado, escolhendo o procedimento mais conservador. BACKGROUND: Severe dysphagia or even aphagia can occur after esophagectomy secondary to necrosis of the ascended organ with severe stricture or complete separation of the stumps. Catastrophic esophageal or gastric disruption drives the decision to "disconnect" the esophagus in order to prevent severe septic complications. The operations employed to re-establish esophageal discontinuity are not standardized and reoperations for re-establishment of the upper digestive transit are a real challenge. METHODS: This is retrospective study collecting the authors experience during 17 years including 18 patients, 14 of them previously submitted to esophagectomy and four to esophagogastrectomy. They were operated on in order to re-establish the upper digestive tract. RESULTS: Redo esophago-gastro-anastomosis was possible in 12 patients, 10 through cervical approach and combined with sternotomy in four in order to perform the new anastomosis. In five patients a new esophago-colo anastomosis was performed. Free jejunal graft interposition was performed in one patient. Complications occurr
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