Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Any time

9 ( 1 )

2019 ( 42 )

2018 ( 295 )

2017 ( 330 )

Custom range...

Search Results: 1 - 10 of 29124 matches for " Mohammad Ali Nilforoushzadeh "
All listed articles are free for downloading (OA Articles)
Page 1 /29124
Display every page Item
The Efficacy of 5% Trichloroacetic Acid Cream in the Treatment of Cutaneous Leishmaniasis Lesions
elaheh haftbaradaran,mohammad ali nilforoushzadeh,Fariba Jaffary
Knowledge & Health Journal , 2010,
Abstract: Introduction: Cutaneous Leishmaniasis (CL) is an endemic parasitic disease in Iran. The residual unpleasant scar of this disease could be a potentially serious psychological threat to the patients. Based on the results of our previous study on the efficacy of trichloroacetic acid (TCA) in the treatment of CL, this study was designed to evaluate the effect of topical 5% TCA cream in the treatment of papulonodular leishmaniasis lesions. Methods: In this case series study, among the patients who were referred to skin disease and leishmaniasis research center(SDLRC), 16 patients with positive direct smear for leishmaniasis were randomly selected for treatment with 5% TCA cream or, twice a day for 8 weeks or up to complete healing(epithelization)of the lesions. At the end of the treatment period, the response rate was assessed as complete cure, partial cure or treatment failure. The size of the scar was measured 6 months after complete epithelization of the lesions. The data were analyzed using SPSS version 12. Results: The mean area of the lesions was 38.81± 81.9 mm2 before the treatment, and 3.6± 9.1 mm2 at 6 month follow up period. Complete cure was achieved in 1 patient (6.3%) at week 2, in 13 patients (86.7%) at week 7, and in all patients at week 8. There was no serious reaction in none of the patients. Only one patient had mild erythema at week 2 and edema at the application site at week 5 which completely was resolved within 2 weeks. Conclusion: Our results showed complete cure in all cases at week 8 without any serious side effects. Considering the efficacy of TCA in decreasing the size of the residual scar and its low cost compared to other treatments, 5% TCA cream could be considered as an alternative modality for intralesional glucantime in the treatment of CL. Further assessment as a double blind randomized clinical trial is warranted
Prevalence of cutaneous lesions , route of infection and distribution of lesions in HIV positive patients in Isfahan province in 1385
Mohammad Ali Nilforoushzadeh,Elaheh Haftbaradaran,Katayoon Tayeri
Dermatology and Cosmetic , 2010,
Abstract: "nBackground and aim: it has been estimated that 70000-100000 cases of HIV infection exist in Iran. The main route of transmission is intravenous drug (IV) injection. Rapid spread of this disease necessitates its prompt diagnosis. About 90% of HIV infected patients express cutaneous manifestations; therefore, recognition of these symptoms may be of help in early diagnosis."n"nMethods: HIV infected patients with suspected skin lesion were referred to Skin Disease and Leishmaniasis Research Center and were examined by an intern contributed in the study. All the information were gathered in data code sheets. Then, all of the patients were visited by the dermatologist for complementary examinations and the results including lesion type, location and duration were recorded in the check list."n"nResults: fifty persons were examined and 42 patients were selected. Prevalence of dermatologic manifestations was as follows: herpes zoster in 23.8%, seborrheic dermatitis in 14.3%, hyperpigmentation in 19%, oropharyngeal candidiasis in 14.3%, folliculitis in 14.3% dermatophytosis in 4.7%, wart in 4.7%, Kaposi’s sarcoma in 2.3%, and drug eruption in 2.3% , 75% of patient who had hyperpigmentation were infected by their sexual partner and 25% via IV injection. 33% of patient who had folliculitis were infected via IV injection, 33% through blood transfusion and 33% by sexual relationship."n"nConclusion: According to the results of this study, paying attention to cutaneous signs HIV/AIDS patients, their early detection and diagnostic and therapeutic measures for them are advocated.
Diphencyprone Induced Vitiligo: A Case Report
Mohammad Ali Nilforoushzadeh,Gelavizh Keshtmand,Fariba Jaffary,Abbas Kheirkhah
Case Reports in Medicine , 2012, DOI: 10.1155/2012/356236
Abstract: Diphencyprone (DCP) is a contact sensitizer which is used to treat dermatological disorders with an immunological origin, such as extensive alopecia areata (AA). Vitiligo is a rare but known side effect of DPCP therapy which is formed in the treatment site or remote areas. In this paper a 37-year-old man developed alopecia totalis with loss of eyebrows and eyelashes who presented some vitiligo patches on his scalp and arm distant from the location of DPCP application and a 42-year-old woman with 25 years history of hair loss and 3 months DPCP application who revealed some vitiligo patches on the scalp with distant to the site of application at the 6th week are reported. Considering the absence of personal and family history of Vitiligo in our two cases, the hypothesis of latent Vitiligo is not proved. The positive patch test in left arm of one of the patients also suggests the direct role of DPCP as the cause of Vitiligo occurrence. As the development of vitiligo by DCP is unpredictable and the depigmentation may persist indefinitely, it is important to inform all patients about this potential adverse effect before starting the treatment.
Antifungal Effect of Echinophora Platyloba’ s Extract against Candida albicans
Majid Avijgan,Massoud Hafizi,Mehdi Saadat,Mohammad Ali Nilforoushzadeh
Iranian Journal of Pharmaceutical Research , 2006,
Abstract: The present study was undertaken to investigate the effectiveness of the ethanolic extract of Echinophora platyloba DC. on Candida albicans. Using the agar dilution method, the growth condition of standard Candida albicans ATCC 10231, cultured on the media containing plant extracts at different concentrations(1, 2, 4, 8, 16, 32, 64, 128 and 256 mg/ml) was studied. The results were recorded twenty one days after the incubation period, maximum time for the growth of fungi. Results showed that the extract of Echinophora platyloba, equal or above the concentration of 2mg/ml, effectively inhibits the growth of Candida albicans. In other words it shows growth on media containing 1mg/ml of the extract. Results of the present study revealed a great promise in the application of Echinophora platyloba extract against Candida albicans. It is concluded that the plant studied could be a good antifungal source.
Treatment of Recalcitrant Electrical Burn Ulcer with Application of Topical Trichloroacetic Acid and Autologous Cultured Fibroblast
Mohammad Ali Nilforoushzadeh, Mohhamad Hossein Nasr Esfahani, Mehr Afarin Fesharaki, Amir Hossein Siadat and Elaheh HaftBaradaran
Cell & Tissue Transplantation & Therapy , 2012, DOI: 10.4137/CTTT.S3779
Abstract: In this case report, we present a case of deep, partial-thickness, recalcitrant electrical burn ulcer that was healed completely using tissue debridement with topical 50% TCA (Trichloroacetic acid) and application of autologous fibroblasts. To the best of our knowledge, this is the first time that the application of topical TCA along with autologous fibroblasts have been used for the treatment of an electrical burn ulcer with a satisfactory result.
The protective effect of 5% azelaic acid and 5% minoxidil combination therapy in reducing skin flap necrosis in rats
Hamidreza Pazoki-Toroudi,Marjan Ajami,Rouhollah Habibey,Mohammad Ali Nilforoushzadeh
Dermatology and Cosmetic , 2010,
Abstract: "nBackgound and Aim: One important limitation of random pattern skin flap in plastic surgery is the necrosis of distant parts of the flap resulting from ischemia. This effect cause unwanted increase in the costs and hospitalization. Previously, large number of factors has been evaluated to decrease the flap necrosis. In present study we used two drugs. Main reason was their mechanism of action that seems to be similar to preconditioning pathways."n"nMethods: Fifty-six male rats were divided into four groups. In two groups 5% minoxidil or 5% azelaic acid were applied topically to the flap area before flap elevation. In some rats of minoxidil treated group, a non selective ATP sensitive potassium channel (KATP) blocker, glibenclamide (0.3mg/kg) was injected i.p. to evaluate the role of this channel in action. In azelaic acid treated rats, some were selected for evaluation of the role of nitric oxide and therefore L-NAME (20 mg/kg), a non-selective iNOS inhibitor, was administered. Seven days after operation, the extent of flap necrosis was calculated."n"nResults: Topical minoxidil or azelaic acid significantly recused necrotic area of skin flap to 42% (P<0.05) and 34% (P<0.01), respectively. Combination of minoxidil and azelaic acid was the most effictive intervantion on reducing of necrotic area to 26%. Glibenclamide abolished protective effect of minoxidil (P<0.001) and L-NAME inhibited the effect of azelaic acid on skin flap survival (P<0.05). Both L-NAME and glibenclamide completely inhibited the effect of combination topical therapy."n"nConclusion: Present study suggested the role of KATP channels on minoxidil pathway and NO on L-NAME pathway of preserving skin flap survival. It seems that there is an overlap between the two pathways; however precise mechanism remained to be determined.
Treatment of atrophic cutaneous leishmaniasis scar using autologous fibroblasts and keratinocytes (a case report and literature review):
Mohammad Ali Nilforoushzadeh,Mohhamad Hossein Nasr Esfahani,Mehr Afarin Fesharaki,Amir Hossein Siadat
Journal of Research in Medical Sciences , 2010,
Abstract: In this case report we present a case of wide, deep, atrophic cutaneous leishmaniasis scar that was improved significantly using injection of autologus fibroblasts, dermabrasion and dressing with autologus keratinocytes and fibroblasts. To our best knowledge, it is the first time that separate cultured fibroblasts and keratinocytes are used in conjunction with dermabrasion for treatment of cutaneous leishmaniasis scar. We have started this procedure as an extensive research on patients with leishmaniasis scar that will be reported in the future.
Soft tissue augmentation by autologous cultured fibroblasts transplantation for treatment of the wrinkles and scars; a case series of 20 patients.
mohammad ali Nilforoushzadeh,amir hosein Siadat,mojgan arian Rad,fariba moulavi
Journal of Research in Medical Sciences , 2010,
Abstract: There are many filler agents for augmentation of static wrinkles and atrophic scar with synthetic, biosynthetic, cadaver, animal and human sources. The current study presents 20 patients with facial wrinkles and lines whom were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry. The mean of improvement for this procedure at the 6 month follow up was 41%. Overall, the results of the current and other studies show that autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars. Although this procedure seems to have low side effects, however, further studies with longer follow up seem to be mandatory to further confirm the permanence of this procedure
Topical effectiveness of different concentrations of nanosilver solution on Leishmania major lesions in Balb/c mice
Mohammad Ali Nilforoushzadeh , Leila Shirani-Bidabadi , Azadeh Zolfaghari-Baghbaderani , Reza Jafari , Motahar Heidari-Beni , Amir Hossein Siadat & Mehdi Ghahraman-Tabrizi
Journal of Vector Borne Diseases , 2012,
Abstract: Background & objectives: Cutaneous leishmaniasis is an infection caused by protozoan genus Leishmania. Althoughglucantime is commonly used for the treatment of leishmaniasis, it has some side effects including increased liverenzymes and electrocardiogram changes. In addition, the drug is expensive, the injection is painful, and researchshows that resistance of parasite to glucantime is growing in different parts of the world. Therefore, scientists arepaying more attention to develop new drugs such as nanosilver solution. The present study is an attempt toevaluate the in vivo topical effects of different concentrations of nanosilver solution in the treatment of leishmaniasislesions.Methods: In all, 90 female Balb/c mice aged 6–8 wk were infected with 2×106 viable stationary-phase promastigotesin the base of tail. Different concentrations (60, 80, 120, 130 and 2000 ppm) nanosilver solution were used in thepresent study to test the efficacy in the treatment of lesions. Clinical control of the infection trends was conductedweekly for 5 wk by measuring lesion diameter with standard Kulis-Vernieh. Data were analyzed by paired t-test,analysis of variance (ANOVA), and Tukey test.Results: Mean lesion diameter pre- and post-treatment did not significantly differ between different treatmentgroups (p >0.05). Likewise, a significant difference in splenic parasite load was also not observed between differenttreatment groups.Interpretation & conclusion: Based on our results, different concentrations of nanosilver are ineffective in reducingmean sizes of lesions.
Petrography and Geochemical Characteristic of Koohrig Intrusive Rocks in Kerman, Iran  [PDF]
Mohammad Baghkhani, Mohammad Ali Arian
Open Journal of Geology (OJG) , 2017, DOI: 10.4236/ojg.2017.75046
Abstract: Koohrig intrusive mass is located in the east of Rafsanjan, Kerman Province, Iran and it is part of because it has cut the sandstone, limestone, shale units and conglomerate of Upper Cretaceous. Its intrusive rock includes quartz, plagioclase and alkali feldspar and its ferromagnesian mineral which is biotite has changed into chlorite. This Intrusive mass is characterized by the presence of metamorphic geochemical studies led to the detection of granite and granodiorite and quartz monzonite rocks.
Page 1 /29124
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.