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Study of cytomorphology of solid pseudopapillary tumor of pancreas and its differential diagnosis
Mehta Neelam,Modi Lopa,Patel Trupti,Shah Manoj
Journal of Cytology , 2010,
Abstract: Background: Solid pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This is an uncommon neoplasm with many pseudonyms, occurring predominantly in young woman under the age of thirty years. Aims: To study the cytomorphological features of six cases of solid and pseudopapillary epithelial neoplasm of pancreas diagnosed on fine needle aspiration cytology (FNAC) in years 2005 to 2007 and its cyto-histological correlation. Materials and Methods: Image-guided FNAs was done in these six patients preoperatively. Alcohol-fixed smears were stained with Papanicolaou stain, cytomorphological findings were evaluated and diagnosis was made. Diagnosis was later confirmed by histology in all cases. Results: All six cases show characteristic cytological features such as hypercellular smears with presence of abundant delicate papillary fragments, dyscohesive cells, monomorphic tumor cells with delicate folded nuclear membranes, and foamy macrophages in the background. Conclusions: Preoperative correct diagnosis of solid pseudopapillary tumor of pancreas is possible on FNAC and by doing so it helps in management of this surgically curable neoplasm.
Administering Anesthesia for Patients with ALS Having a Diaphragmatic Pacemaker Placed: Special Considerations  [PDF]
Molly Kraus, Lopa Misra
Open Journal of Anesthesiology (OJAnes) , 2014, DOI: 10.4236/ojanes.2014.49032
Abstract: Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig’s disease is a relentlessly progressive, fatal disease. Progression of the disease results 3 - 5 years after diagnosis, often from respiratory failure. The diaphragm pacing system (DPS) is a device that stimulates the diaphragm to maximally contract so patients can breathe more effectively. It has been used in patients with neurologic injuries such as spinal cord injury and ALS. From an anesthetic perspective, both the surgery and the patient population present several unique challenges. This case series describes three patients with ALS who had the diaphragmatic pacemaker placed and the anesthetic management during those surgeries.
Anesthetic Management of a Patient with Hermansky-Pudlak Syndrome  [PDF]
Kelly Zach, Lopa Misra
Open Journal of Anesthesiology (OJAnes) , 2015, DOI: 10.4236/ojanes.2015.52007
Abstract: Hermansky-Pudlak Syndrome (HPS) is a rare genetic condition characterized by platelet function abnormalities and oculocutaneous albinism. Other systemic manifestations of the disease include pulmonary fibrosis, granulomatous colitis, impaired renal function, and cardiomyopathy. Due to the systemic extent of the disease, HPS has multiple anesthetic concerns and requires a detailed preoperative evaluation and close perioperative monitoring.
Growth temperature and plant age influence on nutritional quality of Amaranthus leaves and seed germination capacity#
AT Modi
Water SA , 2007,
Abstract: As a leafy vegetable, Amaranthus can be harvested at different stages of plant growth, ranging from young seedlings to the late juvenile stage, but data on the changes in leaf nutritional value with plant age are scanty. The objective of this study was to determine the effect of growth temperature on Amaranthus leaf yield and nutritional quality at different stages of plant growth. Five species, A. hybridus var. cruentus, A. hypochondriacus, A. tricolor, A. thunbergii and A. hybridus were compared for their response to hot (33/27oC), warm (27/21oC) and cool (21/15oC) temperature regimes (day/night) in separate glasshouses. Plants were harvested at 20, 40 and 60 d after sowing and leaf yield, minerals (Ca, P and Fe), total protein content, amino acid (methionine and lysine) content and antioxidant activity (inhibition of linoleic acid oxidation) were determined. Seed yield and germination capacity, during two years of after-ripening, were also determined. Results showed that leaf protein content differed significantly (P < 0.01) between species. It was also significantly (P < 0.01) influenced by the growth temperature and stage of plant growth. The pattern of changes in the amounts of lysine and methionine was comparable to that of protein content, but A. thunbergii showed significantly higher amino acid content than the other species. Amaranthus leaves also contained significantly (P < 0.01) more lysine than methionine, regardless of the species and growth temperature. The phosphorus content of leaves was not significantly affected by temperature and stage of plant development, and there were also no significant differences between species. However, the amounts of both calcium and iron changed significantly (P < 0.05) with stages of plant development and with increasing temperatures for all species. The antioxidant activity of Amaranthus leaves increased consistently with plant age and there were significant (P < 0.01) differences between stages of plant development and growth temperature. Warm temperature regimes were most favourable (P < 0.01) for biomass accumulation in all species. Seed production under cool and hot temperatures significantly (P < 0.01) decreased seed germination capacity for all species, but germination improved in response to after-ripening. It is recommended that for greater nutritional benefit, Amaranthus should be grown under warm conditions and younger leaves are preferable.
Accumulation of Heavy Metals in Freshwater Fish-An Assessment of Toxic Interactions with Calcium
Lopa Ghosh,S. Adhikari
American Journal of Food Technology , 2006,
Abstract: The present investigation deals with the interaction between accumulation of waterborne lead, cadmium and chromium with different calcium concentration (1.0, 2.0, 3.0 and 4.0 mM L-1) in Cirrhina mrigala fingerlings in the laboratory. There was no mortality occurred in metal alone and metal treated with calcium. At the beginning there was no significant differences observed between Pb, Cd and Cr alone and combination with calcium in muscle as well as whole body at lower calcium concentration, but with increasing exposure period marked differences were observed. In muscle tissue accumulations was very much lower compared to whole body and significantly lower below human consumption level. In binary mixtures of Pb, Cd and Cr with calcium, the calcium compound was found to consistently reduce the toxic effect as well as accumulation of Pb, Cd and Cr compounds. Increased Ca levels showed lower transfer of Pb, Cd and Cr from water to the gills which resulted slower transfer of metal from the gills to the blood indicated lower accumulation rates in muscle tissue compared to metal without Ca. An increase in calcium concentration of approximately 3 and 4 mM L-1 resulted in a 46 and 54% decrease of Pb uptake, 55 and 58% of Cd and 41 and 53% of Cr uptake in whole fish at 28 days exposure period. There is an inverse relationship between calcium concentration in the water and metal uptake in whole body, muscle as well as gills of the Cirrhina mrigala. Calcium has strong antagonistic effect on Pb, Cd and Cr accumulation and toxicity. Predicted and experimental values of Pb, Cd and Cr concentration in fish body treated with calcium verified in terms of root mean square percent deviation and correlation coefficient which exhibit fair agreement.
La educación más allá del aula. Una experiencia comunitaria con la discapacidad intelectual
Diego Lopa Peralto
En Blanco y Negro : Revista sobre Docencia Universitaria , 2012,
Abstract: Desde la dualidad que representa mi desempe o profe-sional, como psicólogo de una asociación de personas con discapacidaded intectual y profesor universitario, sentí, desde el primer día que pisé un aula, la necesi-dad casi obsesiva de acercar ambos mundos. Cómo es posible transmitir a un ser humano, y más a un futuro profesional de la educación, el concepto de diversidad en un aula donde todos eran básicamente iguales? En el otro lado, estaban los usuarios de la asociación, personas en su mayoría afectadas por el síndrome de Down que acuden regularmente para recibir una atención y a los que, más allá de alejarlos de la sociedad, trataba de pre-parar para una vida autónoma e inclusiva. Sin embargo, qué paradoja: qué podía transmitirles yo sobre la vida, si la vida estaba allí fuera? Esta es una experiencia de integración de recursos donde alumnos de magisterio y personas con discapacidad caminarán en un proceso de aprendizaje recíproco
Time, uncertainty, relativity, normality and modern medicine
Kothari M,Mehta Lopa
Journal of Postgraduate Medicine , 1979,
Cells and Yin-Yang polarity- (Towards greater similarity between the animate and the inanimate)
Kothari M,Mehta Lopa
Journal of Postgraduate Medicine , 1978,
Abstract: A cell-plant or animal-is proving a bioelectric wonder al-ready boasting of pyro-, piezo-, ferroelectricity, solid state and electretism as eminent exhibits and probable functional mechan-isms. A cell, its parts, and its products owe the bioelectric boon to inherent and universal polarity pregnant with dipolar electro-magnetic moment. The cytologic bipolarity prompts a hypothesis that the cell and its world may be no exception to the working of Yin-Yang, the Taoistic concept o f all-pervading reality. Nuclear, cytoplasmic, gametic and zygotic considerations compellingly suggest that Yin-Yang does prevail, making us and′ our cells basically field-effects, thus erasing further the distinction between male and female, animate and inanimate, biomass and bioenergy.
Utopia and modern medicine
Kothari M,Mehta Lopa
Journal of Postgraduate Medicine , 1978,
Cancerology: Science or non-science?- (a plea for cancerrealism)
Kothari M,Mehta Lopa
Journal of Postgraduate Medicine , 1978,
Abstract: Cancerology is, by all counts, a non-science, which may be defined as a so-called scientific pursuit in the teeth of obvious proofs to the contrary. Not one facet of current cancerology-etiology, diagnosis, therapy, prevention, and its latest fad, immunology -enjoys any clear, rational basis. No wonder that the outcome of the whole gargantuan effort is "precisely nil", with possibly more people living on, than dying of, cancer. The pathway to the logical-ly acceptable and comprehensible science is simple-to give cancer its due place in biology, to give the cancer cell its rightful place of but a form of cytodifferentiation, and to give the cancer therapist the supremely relevant role of a palliator. To talk of cancer cure is to deny - the cytosomatic reality that cancer is one′s own flesh and blood. Being a part of one′s self, cancer need not always be treated. I f a therapist has the right and obligation to diagnose, treat, and prognose upon a cancer patient, he has, hitherto unrecognized, equal right and obligation, not to do one or all of these. Cancer-realism offered in this article can guide a therapist to this often necessary path of inaction.
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