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Search Results: 1 - 10 of 204 matches for " Mizuho Nishio "
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Classification of Emphysema Subtypes: Comparative Assessment of Local Binary Patterns and Related Texture Features  [PDF]
Mizuho Nishio, Hisanobu Koyama, Yoshiharu Ohno, Kazuro Sugimura
Advances in Computed Tomography (ACT) , 2015, DOI: 10.4236/act.2015.43007
Abstract: The purpose of this study was to assess usefulness of local binary patterns (LBP) and related texture features, namely completed local binary patterns (CLBP) and local ternary patterns (LTP), for the classification of emphysema subtypes on low-dose CT images. Fifty patients (34 men and 16 women; age, 67.5 ± 10.1 years) who underwent low-dose CT (60 mAs) were included. They were comprised of 17 never smokers, 13 smokers without COPD, and 20 smokers with COPD. By consensus reading of low-dose CT images from these patients, two radiologists selected 3681 nonoverlapping regions of interest (ROIs) and annotated them as one of the following three classes: normal tissue, centrilobular emphysema, and paraseptal emphysema. From these ROIs, histogram of CT densities, LBP, CLBP, and LTP were calculated, and the 3 types of texture histograms were concatenated with the CT density histogram. These 3 types of histograms (referred to as combined LBP, combined CLBP, and combined LTP) were used to classify ROI using linear support vector machine. For each type of the combined histogram, the accuracy of classification was determined by patient-based 10-fold cross validation. The best accuracy of combined LBP, combined CLBP, and combined LTP were 81.36%, 82.99%, and 83.29%, respectively. Compared to the classification accuracies obtained with combined LBP, those with combined LTP or combined CLBP were consistently improved. In conclusion, the results of this study suggest that, on low-dose CT, LTP and CLBP were more useful for the classification of emphysema subtypes than LBP.
Tumor Segmentation on 18F FDG-PET Images Using Graph Cut and Local Spatial Information  [PDF]
Mizuho Nishio, Atsushi K. Kono, Kazuhiro Kubo, Hisanobu Koyama, Tatsuya Nishii, Kazuro Sugimura
Open Journal of Medical Imaging (OJMI) , 2015, DOI: 10.4236/ojmi.2015.53022
Abstract: The purpose of this study was to develop methodology to segment tumors on 18F-fluorodeoxyg- lucose (FDG) positron emission tomography (PET) images. Sixty-four metastatic bone tumors were included. Graph cut was used for tumor segmentation, with segmentation energy divided into unary and pairwise terms. Locally connected conditional random fields (LCRF) were proposed for the pairwise term. In LCRF, three-dimensional cubic window with length L was set for each voxel, and voxels within the window were considered for the pairwise term. Three other types of segmentation were applied: region-growing based on 35%, 40%, and 45% of the tumor maximum standardized uptake value (RG35, RG40, and RG45, respectively), SLIC superpixels (SS), and region-based active contour models (AC). To validate the tumor segmentation accuracy, dice similarity coefficients (DSC) were calculated between the result of each technique and manual segmentation. Differences in DSC were tested using the Wilcoxon signed-rank test. Mean DSCs for LCRF at L = 3, 5, 7, and 9 were 0.784, 0.801, 0.809, and 0.812, respectively. Mean DSCs for the other techniques were: RG35, 0.633; RG40, 0.675; RG45, 0.689; SS, 0.709; and AC, 0.758. The DSC differences between LCRF and other techniques were statistically significant (p < 0.05). Tumor segmentation was reliably performed with LCRF.
Comparing Lifestyle Convenience of Multiple Daily Injection and Continuous Subcutaneous Insulin Infusion  [PDF]
Ikuko Nishio
Open Journal of Nursing (OJN) , 2017, DOI: 10.4236/ojn.2017.712098

Aim: This study investigated the lifestyle convenience of Insulin therapy for adult women patients with type 1 diabetes. Methods: Participants were type 1 diabetes adult women patients who switched from multiple daily injection (MDI) therapy to Continuous Subcutaneous Insulin Infusion (CSII) therapy. We conducted semi-structured interviews with participants. To analyze, we referenced the classification table of Hamada’s study comparing the usefulness of both the NovoPen? and CSII. Semi-structured interviews were conducted with the research subjects. The questions focused mainly on diabetes management, instrument operation, everyday life, and social, psychological and lifestyle convenience aspects during MDI and CSII. Results: Research subjects were 4 women patients with type 1 diabetes. The average age was 35.3 ± 6.24 (SE) years old. Participants were undergoing MDI therapy; however, in the middle, they switched to CSII therapy. CSII therapy is convenient in terms of diabetes management, social and psychological. MDI therapy is convenient in terms of instrument operation and daily life. Compared to MDI therapy, CSII therapy is less convenient in terms of instrument operation and everyday life. However, since CSII therapy has more stable HbA1c and blood glucose levels compared to MDI therapy, it is more convenient in terms of social and psychological aspects and reduces those burdens. About economy CSII therapy, patients paid about 5000 yen more per month compared to MDI therapy. Conclusion: It is believed that patients prioritize therapeutic effects, and choose CSII, which is stable in psychological and social aspects, even though it is inconvenient with life.

Contributions of Cytogenetics and Molecular Cytogenetics to the Diagnosis of Adipocytic Tumors
Jun Nishio
Journal of Biomedicine and Biotechnology , 2011, DOI: 10.1155/2011/524067
Abstract: Over the last 20 years, a number of tumor-specific chromosomal translocations and associated fusion genes have been identified for mesenchymal neoplasms including adipocytic tumors. The addition of molecular cytogenetic techniques, especially fluorescence in situ hybridization (FISH), has further enhanced the sensitivity and accuracy of detecting nonrandom chromosomal translocations and/or other rearrangements in adipocytic tumors. Indeed, most resent molecular cytogenetic analysis has demonstrated a translocation t(11;16)(q13;p13) that produces a C11orf95-MKL2 fusion gene in chondroid lipoma. Additionally, it is well recognized that supernumerary ring and/or giant rod chromosomes are characteristic for atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma, and amplification of 12q13–15 involving the MDM2, CDK4, and CPM genes is shown by FISH in these tumors. Moreover, myxoid/round cell liposarcoma is characterized by a translocation t(12;16)(q13;p11) that fuses the DDIT3 and FUS genes. This paper provides an overview of the role of conventional cytogenetics and molecular cytogenetics in the diagnosis of adipocytic tumors.
Forma o do esmalte dentário, novas descobertas, novos horizontes
Clarice Nishio
Revista Dental Press de Ortodontia e Ortopedia Facial , 2008, DOI: 10.1590/s1415-54192008000400002
The classification of orbits on certain exceptional Jordan algebra under the automorphism group
Akihiro Nishio
Mathematics , 2010,
Abstract: Let $\mathcal{J}^1$ be the real form of complex simple Jordan algebra with the automorphism group $G$ of type $F_{4(-20)}$. Explicitly, we give the orbit decomposition of $\mathcal{J}^1$ under the action of $G$ and determine the Lie group structure of stabilizer for each $G$-orbit on $\mathcal{J}^1$.
The Iwasawa decomposition and the Bruhat decomposition of the automorphism group on certain exceptional Jordan algebra
Akihiro Nishio
Mathematics , 2011,
Abstract: Let $\mathcal{J}^1$ be the real form of a complex simple Jordan algebra such that the automorphism group is $\mathrm{F}_{4(-20)}$. By using some orbit types of $\mathrm{F}_{4(-20)}$ on $\mathcal{J}^1$, for $\mathrm{F}_{4(-20)}$, explicitly, we give the Iwasawa decomposition, the Oshima--Sekiguchi's $K_{\epsilon}-$Iwasawa decomposition, the Matsuki decomposition, and the Bruhat and Gauss decompositions.
History and Current Situation of Education for Children with Disabilities in Cambodia: A Gray Literature Review  [PDF]
Akihiro Nishio
Creative Education (CE) , 2019, DOI: 10.4236/ce.2019.108125
Abstract: In this paper we report on historical changes in the Cambodian education system, the current state of education for persons with disabilities. This report is based on interviews with Mr. Pen Thavy, materials provided by the Cambodian government, and other supporting documents. The first turning point in Cambodia’s movement toward educating children with disabilities was the “Convention on the Rights of the Child” adopted by the United Nations General Assembly on November 20, 1989. Cambodia ratified this treaty in 1992. The concept of “Education for All” was adopted into educational policy in Cambodia. The first law directly mentioning education for children with disabilities was the “Educational law” enacted in 2007. The Schools specialized in education for children with disabilities are operated by three NGO schools. One is the KrousarThmey Foundation which operates 8 schools for?children with visual/hearing impairment. Another one is Rabbit-School which?accepted 26 students in the special class, 25 students in the readiness class for children aged 4-to-6 years, 18 students in classes for children with cerebral palsy and 46 students in the integrated class. The third one is Komar Pilar Foundation which does not have coordination with the government and is not officially regarded as a school. According to the data which we were given, the total number of students with all disabilities was 44,759 in primary schools and 6787 in secondary schools in 2017. Most common disability was emotional disturbance in primary schools and visual impairment in junior high schools. The data show that the number of invisible disabilities such as behavioral disorders, learning disability, intellectual disability and emotional disturbance varied so much in each province. Misidentification of disabilities can be considered a cause for it.
The Direction of Research on Active Aging and Healthy Life Expectancy in Japan  [PDF]
Atsuko Tokushige, Daiji Araki, Miyuki Suzuki, Yukie Iwasaki, Mizuho Ozawa
Open Journal of Nursing (OJN) , 2014, DOI: 10.4236/ojn.2014.47050

In Japan, 18.1% of the population known as baby-boomers will become the late-stage elderly in 2025, thereby needing a foundation to support this change. The Japanese Ministry of Health, Labour and Welfare is promoting the development of a regional comprehensive system allowing the elderly to continue living in their familiar surroundings. However, a care shortage is inevitable unless elders are able to age in good health, regardless of the system’s level of enhancement. This study aims to review the literature on active aging, clarify trends in clinical operations undertakings and research in Japan, and consider relevant research issues. After combining the search results of “active aging” and “healthy life expectancy,” we used a text mining technique to analyze the abstracts of 120 original articles and 213 reviews, commentaries, and features. Eight categories were extracted from the original articles: health statistics, gender, age, etc. From the reviews, commentaries, and features, 16 categories were extracted: orientation, disease, and living, etc. Cerebrovascular disease and osteoporosis were the most common diseases covered in the original articles; there has been a substantial amount of research on “active aging” and “healthy life expectancy” because they can easily lead to being bedridden and to a decrease in QOL. In the reviews, commentaries, and features, lifestyle-related diseases and menopause rather than cerebrovascular disease and osteoporosis, were extracted. The categorical differences found in the original articles may be due to the possibility that Japanese researchers are publishing their research abroad rather than in Japan or they submit research on topics that are guaranteed to be published at home or abroad. Little research has been conducted using the terms, “active aging” and “healthy life expectancy,” evidenced by the small number of studies generated. Preparations for 2025 will require an increase in the number of studies from the perspective of “active aging” and “healthy life expectancy.”

Efficacy and Tolerability of Candesartan Cilexetil and Amlodipine in Patients with Poorly Controlled Essential Hypertension  [PDF]
Kazuaki Nishio, Takeshi Kondo, Youichi Kobayashi
International Journal of Clinical Medicine (IJCM) , 2011, DOI: 10.4236/ijcm.2011.22012
Abstract: Current treatment guidelines for hypertension in both Europe and the USA stress the importance of aggressive blood pressure control. When monotherapy is not enough to reach treatment targets, there is a need for combination regi-mens that have both high efficacy and good tolerability. The aim of this study is to evaluate the efficacy and toler-ability of the combination therapy candesartan and amlodipine in patients with hypertension not satisfactorily controlled by monotherapy. Patients with uncomplicated essential hypertension not satisfactorily controlled by monotherapy, which is candesartan 8 mg or amlodipine 5 mg, were eligible. Candesartan 8 mg and amlodipine 5 mg were given for 12 weeks. 13 patients who received candesartan 8 mg previoursly were assigned to the candesartan group and 8 patients who received amlodipine 5 mg previoursly were assigned to the amlodipine group. Sitting systolic blood pressure (SBP) at baseline was 151.9 ± 11.6 mmHg in the candesartan group, and 154.6 ± 7.6 mmHg in the amlodipine group. Sitting diastolic blood pressure (DBP) was 93.2 ± 13.1 in the candesartan group, and 80.4 ± 14.7 in the amlodipine group. DBP in the amlodipine group was lower than that in the cadesartan group (P = 0.036). After the combination therapy, SBP was significantly reduced in the two groups. DBP showed significant reduction in the amlodipine group. The rate of achieving blood pressure goals was 4% at baseline and significantly increased to 58% after the combination therapy. These results showed that candesartan 8 mg/amlodipine 5 mg are effective lowering blood pressure after 12 weeks in patients not adequately controlled by monotherapy.
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