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Search Results: 1 - 10 of 156016 matches for " Miot Hélio Amante "
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Tamanho da amostra em estudos clínicos e experimentais Sample size in clinical and experimental trials
Hélio Amante Miot
Jornal Vascular Brasileiro , 2011, DOI: 10.1590/s1677-54492011000400001
Epidemiologia do carcinoma basocelular
Chinem, Valquiria Pessoa;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2011, DOI: 10.1590/S0365-05962011000200013
Abstract: basal cell carcinoma is the most common malignant neoplasm in humans and its incidence has increased over the last decades. its high frequency significantly burdens the health system, making the disease a public health issue. despite the low mortality rates and the rare occurrence of metastases, the tumor may be locally invasive and relapse after treatment, causing significant morbidity. exposure to ultraviolet radiation is the main environmental risk factor associated with its cause. however, other elements of risk are described, such as light skin phototypes, advanced age, family history of skin carcinoma, light eyes and blond hair, freckles in childhood and immunosuppression. behavioral aspects such as occupational sun exposure, rural labor and sunburns at a young age also play a role. between 30% and 75% of the sporadic cases are associated with patched hedgehog gene mutation, but other genetic changes are also described. the tumor is commonly found in concomitance with skin lesions related to chronic sun exposure, such as actinic keratoses, solar lentigines and facial telangiectasia. the prevention of basal cell carcinoma is based on the knowledge of risk factors, early diagnosis and treatment, as well as on the adoption of specific measures, particularly in susceptible populations. the authors present a review of the epidemiology of basal cell carcinoma.
Actinic keratosis: a clinical and epidemiological revision
Schmitt, Juliano Vilaverde;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2012, DOI: 10.1590/S0365-05962012000300012
Abstract: actinic keratoses are benign intraepithelial skin neoplasms constituted by atypical proliferation of keratinocytes that may evolve to squamous cell carcinoma. they develop in photoexposed skin areas; they are induced mainly by ultraviolet radiation and are considered cutaneous markers of chronic exposure to sunlight. they develop mainly in adults and older, fair skinned individuals, and are the fourth most common cause of dermatologic consultation in brazil. damage to the apoptosis pathway in photoexposed epithelium favors cellular proliferation and the permanence of the lesions. in this revision, the authors assemble the main epidemiological data regarding this disease and suggest that strategies to identify risky phenotypes, early diagnosis, adequate treatment, clinical follow-up, stimulus to skin self examination, photoeducation and photoprotection should be promoted with the aim of avoiding the progression to malignancy and also the prevention and the diagnose of concomitant neoplasms also induced by ultraviolet radiation.
Análise morfométrica do colágeno dérmico a partir da segmenta??o por conglomerados (clusters) de cor
Miot, Hélio Amante;Brianezi, Gabrielli;
Anais Brasileiros de Dermatologia , 2010, DOI: 10.1590/S0365-05962010000300010
Abstract: morphometric analysis of dermal collagen can provide quantitative support to dermatologic research. the authors of this article disclose a technique of digital image analysis which allows the identification of microscopic structures by color cluster segmentation regarding the estimate intensity and density of dermal collagen fibers.
Inflama??o de queratoses seborreicas múltiplas induzida por quimioterapia com gencitabina
Siqueira, Caio Roberto Shwafaty de;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2009, DOI: 10.1590/S0365-05962009000400014
Abstract: there are several common mucocutaneous adverse effects related to chemotherapy, either by direct cytotoxic action or by hypersensitivity to the drugs. the authors report inflammation in multiple seborrheic keratoses after chemotherapy with gemcitabine in a patient under treatment for pancreatic cancer. moreover, they discuss the relative benignity of this event and warn about the need to correctly identify systemic chemotherapy-induced skin adverse effects.
Padr?es clínicos de acne em mulheres de diferentes faixas etárias
Schmitt, Juliano Vilaverde;Masuda, Paula Yoshiko;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2009, DOI: 10.1590/S0365-05962009000400005
Abstract: background: acne is a frequent skin disease that occurs in both sexes and all age-groups. women present several clinical disease patterns; moreover, persistence after adolescence is common. objective: to analyze clinical and epidemiological characteristics associated with different age-groups affected by acne in women. methods: cross-sectional study involving female patients diagnosed with acne, at a general dermatology outpatient clinic. variables related to disease and patients were assessed through a standardized questionnaire. results: one hundred and three women were assessed. the average age of patients at the time of the consultation was 21.7 ± 7.3 years. two groups were defined (cut-off age of 21 years), with means of 15.8 ± 2.3 and 28.0 ± 5.1 years. there was correlation between disease duration and current age (r=0.7). there were group differences among frequencies of covariables: combined oral contraceptive (or=48.1), lesions located on upper chest (or=11.6), lesions on upper dorsum (or=0.2), predominance on upper half of face (or=0.1) and age at disease onset (or=1.8). among adult women, 80% reported acne onset before 20 years of age. conclusion: chronologic and topographic patterns of female acne in different age-groups were defined, reinforcing the importance of an individualized diagnostic and therapeutic approach.
Case for diagnosis
Silva, Sabrina Bortoletto Gomes da;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2012, DOI: 10.1590/S0365-05962012000200025
Abstract: we report the case of a 58-year-old white female with parkinson's disease. she evolved to an extensive livedo reticularis in the limbs and abdomen after commencing treatment with amantadine. we discuss the diagnostic approach to livedo reticularis and its differential diagnoses, emphasizing that the drug etiology must be considered when investigating livedo reticularis.
Vasculite cutanea crioglobulinêmica induzida por infec??o cr?nica pelo vírus da hepatite C
Paix?o, Maurício Pedreira;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2008, DOI: 10.1590/S0365-05962008000200009
Abstract: cutaneous vasculitis may represent a great clinical challenge, even after careful dermatological examination and laboratory assessment. the authors present a case of cutaneous cryoglobulinemic vasculitis associated to chronic hepatitis c virus infection, pointing out the importance of the dermatological examination for diagnostic investigation. they discuss about the importance of defining the etiology and making correct classification for appropriate prognosis and treatment of cutaneous vasculitis.
Você conhece esta síndrome?
Paix?o, Maurício Pedreira;Miot, Hélio Amante;
Anais Brasileiros de Dermatologia , 2007, DOI: 10.1590/S0365-05962007000300011
Abstract: the oculoauriculovertebral syndrome, more commonly known as the goldenhar syndrome, can be diagnosed by the dermatologist. findings such as hypoplasia/aplasia of the auricular pavilion, vertebral alterations and accessory tragi are the key elements for the suspicion of the syndrome. its identification is of utmost importance, given the possibility of other systemic alterations, with impact also on the patient's prognosis. after confirmation of the diagnosis, an integral and multidisciplinary attention is important, because of the plurality of manifestations that can occur in the syndrome.
Reforma ortográfica da língua portuguesa no Brasil e na dermatologia
Miot, Hélio Amante;Ramos, Paulo Müller;
Anais Brasileiros de Dermatologia , 2011, DOI: 10.1590/S0365-05962011000100036
Abstract: the brazilian portuguese language orthographic reform has promoted changes in writing in less than 2% of its lexis. however, these changes have affected medical practice. the authors present in this article the main changes in the orthographic rules and gather a group of words that have had their spelling altered by this new language reform emphasizing the dermatological terms.
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