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Search Results: 1 - 10 of 24713 matches for " Min Ni "
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A Novel Regulator Couples Sporogenesis and Trehalose Biogenesis in Aspergillus nidulans
Min Ni, Jae-Hyuk Yu
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000970
Abstract: Trehalose is a compatible osmolyte produced by bacteria, fungi, insects and plants to protect the integrity of cells against various environmental stresses. Spores, the reproductive, survival and infection bodies of fungi require high amounts of trehalose for long-term survival. Here, via a gain-of-function genetic screen, we identify the novel regulator VosA that couples the formation of spores and focal trehalose biogenesis in the model fungus Aspergillus nidulans. The vosA gene is expressed specifically during the formation of both sexual and asexual spores (conidia). Levels of vosA mRNA and protein are high in both types of spore. The deletion of vosA results in the lack of trehalose in spores, a rapid loss of the cytoplasm, organelles and viability of spores, and a dramatic reduction in tolerance of conidia to heat and oxidative stress. Moreover, the absence of vosA causes uncontrolled activation of asexual development, whereas the enhanced expression of vosA blocks sporulation, suggesting that VosA also functions in negative-feedback regulation of sporogenesis. VosA localizes in the nucleus of mature conidia and its C-terminal region contains a potential transcription activation domain, indicating that it may function as a transcription factor primarily controlling the late process of sporulation including trehalose biogenesis. VosA is conserved in most fungi and may define a new fungus-specific transcription factor family.
Health Risk Assessment on Rural Drinking Water Safety —A Case Study in Rain City District of Ya’an City of Sichuan Province  [PDF]
Fuquan NI, Guodong LIU, Huazhun REN, Shangchuan YANG, Jian YE, Xiuyuan LU, Min YANG
Journal of Water Resource and Protection (JWARP) , 2009, DOI: 10.4236/jwarp.2009.12017
Abstract: Taking Rain City District of Ya’an for example, this paper based on ComGIS (Component Object Model Geographic Information System) platform takes comprehensive and systematic detection on the exposure dose of chemical carcinogens and non-carcinogens from drinking water sources in this region and discusses health risk assessment of single factor and the whole health risk assessment. As, Hg, Cr, Pb, Cd and fluorides in some drinking water sources of Rain City District are analyzed according to Standards For Drinking Wa-ter Quality (GB5749-2006). A health risk assessment model called USEPA is also applied to drinking water health risk assessment and management countermeasure is proposed. The results show that the greatest health risk for individual person per year is caused by Cr(VI). The health risk of carcinogens is much higher than that of non-carcinogens: the greatest risk value due to non-carcinogen pollutants is caused by fluoride (F), achieving 1.05×10-8/a. The ranking of risk values due to non-carcinogen pollutants by drinking water is Pb>fluoride (F)>Hg, within Pb accounting for 44.77%, fluo-ride (F) accounting for 34.30% and Hg accounting for 20.92%. The average individual carcinogenesis annual risk of Cr(VI) is the greatest, achieving 8.91×10-4/a. The ranking of risk value due to chemical carcinogen by rural drinking water of Ya’an is Cr6+>As>Cd, within Cr6+ accounting for 91.12%, As accounting for 5.89% and Cd accounting for 3.00%. Based on this, the strategy and measures of the health risk management are put forward. This study has worked efficiently in practice. Compared with the same kind of methods which have been found, the paper has the outstanding results for the health risk assessment of the rural drinking water safety.
A New Simple Route to ZnS Quantized Particles with Tunable Size and Shape, and Size/Shape-Dependent Optical Properties  [PDF]
Pengfei Hu, Yali Cao, Yanyan Lou, Bo Lu, Min Shao, Jiansen Ni, Meng Cao
Advances in Materials Physics and Chemistry (AMPC) , 2013, DOI: 10.4236/ampc.2013.31003

With the features of convenience and eco-friendly, the low-temperature solid-state reaction synthesis was successfully developed as a new approach to prepare quantum-sized ZnS nanocrystals. One major achievement is that the size and shape of ZnS nanocrystals can be tuned by adjusting the surfactant and its feed. The UV-Vis absorption spectra of quasispherical and one-dimensional quantum-sized ZnS nanocrystals all showed a blue-shift from the bulk counterpart, indicating large quantum confinement effects of ZnS nanocrystals. These ZnS nanocrystals all showed well-defined excitonic emission features. Contrastive studies on photoluminescence performances indicated that the bandedge emission experienced only the size-dependent quantum confinement effect, while the trap-state emission experienced the size- and shape-dependences. So we can design a purposeful synthesis route to ZnS nanocrystals with target luminescence emission performances.


Effects of Arsenic Treatments on Saponin Content and Heterogeneity Extracted from Rhizome and Main Root of Panax notoginseng Plants Grown in Shaded Field  [PDF]
Yanqun Zu, Jinjin Sun, Ni Ma, Qiang Min, Guangquan Feng, Jiong Wu, Yuan Li
Journal of Geoscience and Environment Protection (GEP) , 2016, DOI: 10.4236/gep.2016.47003
Abstract: As contamination is one of important factors to Panax notoginseng quality and safety. Saponin is one of important compounds with the medicinal values of P. notoginseng. The impact of soil As on production of saponin of P. notoginseng knew very little. This study was performed to determine content and heterogeneity of saponins from P. notoginseng and its mechanisms upon treatments with different concentration levels of As in soil. Plants of P. notoginseng were treated with arsenic [As (V)] at 0, 20, 80, 140, 20 and 260 mg/kg concentration levels which were supplied as sodium arsenate (Na3AsO4). These experimental plants were grown in shade condition in a greenhouse. Plants were harvested at vigorous vegetative growth and fruit ripening stages, separately. Effects of As treatments on saponin content, and heterogeneity of monomers in the mixtures of notoginesenosides and ginsenosides, enzymatic activity and gene expression level of squalene synthetase were determined for rhizome and main root tissues. Results show that(1) Of all the As treatments from the lowest to the highest concentration levels, the As content in both rhizome and main roots from As-treated plants was within the standard level for superior products derived from P. notoginseng. The content of notoginsenosides from all tissues except the main roots at fruit ripening stage, was 5% higher than the standard level specified in the Chinese Pharmacopoeia; (2) The treatment of As at 20 mg/kg led to an 3.5% - 183.9% increases in total notoginesenosides content in rhizome and main roots, respectively. Treatments with the highest As concentration at 260 mg/kg resulted in a significant decline in total notoginsenosides content, and lower enzymatic activity and gene expression levels of squalene synthetase; (3) Under As treatment conditions, the ratio of Rb1/Rg1 decreased but the ratio of (Rb1 + Rg1)/R1 increased in both?rhizomes and main roots. Conclusively, this study demonstrated that low As concentration (20 - 80 mg/kg) treatments resulted in higher notoginsenoside content in P. notoginseng. However, treatments with high As concentrations had an adverse effect.
Texture/Microstructural Evolution and Mechanical Properties of a Hot and Cold Rolled Al-Mg-Si-Cu Alloy  [PDF]
Yihan Wang, Lixin Zhang, Xiaohui Yang, Kai Li, Song Ni, Yong Du, Min Song
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2017, DOI: 10.4236/jmmce.2017.54018
Abstract: The evolutions of texture, microstructure as well as mechanical properties of an Al-Mg-Si-Cu alloy during hot and cold rolling were investigated by TEM, EBSD and X-ray diffraction in this study. The results revealed that formation of sub-grain boundaries and <110>//RD fiber texture after hot rolling is beneficial to the increase of the elongation of the alloy. The shear texture of <110>//RD fiber and γ-fiber occupies a dominant role during the hot rolling process, while the main texture during the cold rolling process is the rolling texture of β-fiber. β-fiber and τ-fiber texture components are identified as two main types of texture components during cold rolling, and the Brass component {011}<211> is transformed into Goss component {011}<100> with the increase of the deformation.
Treatment Outcome of Papillary Carcinoma Confined to the Thyroid Isthmus  [PDF]
Hui Huang, Shao-Yan Liu, Song Ni, Zong-Min Zhang, Xiao-Lei Wang, Zhen-Gang Xu
Journal of Cancer Therapy (JCT) , 2016, DOI: 10.4236/jct.2016.712093
Abstract: Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. Methods: Thirty-four patients with PTC in isthmus are managed by surgery in National Cancer Center/Cancer Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College from 1985-2008. Demographic data, surgical procedures, pathological features, stages and outcomes are analyzed. Results: Seven patients were men and 27 were women. The median age was 41 years (range, 20 - 71). Twenty-five patients were treated with thyroid isthmusectomy or wide field isthmusectomy, five with hemithyroidectomy (lobectomy and isthmusectomy) and four with hemithyroidectomy and partial resection of the contralateral lobe. Twenty-eight patients had a pathologically T1 lesion (pT1); two patients had a pT2 lesion and four had a pT3 lesion. Five patients (14.7%) had papillary carcinoma detected in one of the pretracheal lymph nodes. Thirty-two patients had a solitary lesion confined to the thyroid isthmus. One patient had two lesions in the thyroid isthmus and another one had two lesions located in the thyroid isthmus and right lobe respectively. With a median follow-up of 94 months (range, 12 - 274), two patients had a recurrence and both survived after a re-operation. There was no regional lymph node or distant organ recurrences. No deaths occurred. Conclusions: Isthmusectomy or wide field isthmusectomy could be a
Hypersensitive to Red and Blue 1 and Its Modification by Protein Phosphatase 7 Are Implicated in the Control of Arabidopsis Stomatal Aperture
Xiaodong Sun equal contributor,Xiaojun Kang equal contributor,Min Ni
PLOS Genetics , 2012, DOI: 10.1371/journal.pgen.1002674
Abstract: The stomatal pores are located on the plant leaf epidermis and regulate CO2 uptake for photosynthesis and the loss of water by transpiration. Their stomatal aperture therefore affects photosynthesis, water use efficiency, and agricultural crop yields. Blue light, one of the environmental signals that regulates the plant stomatal aperture, is perceived by the blue/UV-A light-absorbing cryptochromes and phototropins. The signal transduction cascades that link the perception of light to the stomatal opening response are still largely unknown. Here, we report two new players, Hypersensitive to Red and Blue 1 (HRB1) and Protein Phosphatase 7 (PP7), and their genetic and biochemical interactions in the control of stomatal aperture. Mutations in either HRB1 or PP7 lead to the misregulation of the stomatal aperture and reduce water loss under blue light. Both HRB1 and PP7 are expressed in the guard cells in response to a light-to-dark or dark-to-light transition. HRB1 interacts with PP7 through its N-terminal ZZ-type zinc finger motif and requires a functional PP7 for its stomatal opening response. HRB1 is phosphorylated in vivo, and PP7 can dephosphorylate HRB1. HRB1 is mostly dephosphorylated in a protein complex of 193 kDa in the dark, and blue light increases complex size to 285 kDa. In the pp7 mutant, this size shift is impaired, and HRB1 is predominately phosphorylated. We propose that a modification of HRB1 by PP7 under blue light is essential to acquire a proper conformation or to bring in new components for the assembly of a functional HRB1 protein complex. Guard cells control stomatal opening in response to multiple environmental or biotic stimuli. This study may furnish strategies that allow plants to enjoy the advantages of both constitutive and ABA-induced protection under water-limiting conditions.
Security Enhancement Mechanism Based on Contextual Authentication and Role Analysis for 2G-RFID Systems
Wan Tang,Min Chen,Jin Ni,Ximin Yang
Sensors , 2011, DOI: 10.3390/s110706743
Abstract: The traditional Radio Frequency Identification (RFID) system, in which the information maintained in tags is passive and static, has no intelligent decision-making ability to suit application and environment dynamics. The Second-Generation RFID (2G-RFID) system, referred as 2G-RFID-sys, is an evolution of the traditional RFID system to ensure better quality of service in future networks. Due to the openness of the active mobile codes in the 2G-RFID system, the realization of conveying intelligence brings a critical issue: how can we make sure the backend system will interpret and execute mobile codes in the right way without misuse so as to avoid malicious attacks? To address this issue, this paper expands the concept of Role-Based Access Control (RBAC) by introducing context-aware computing, and then designs a secure middleware for backend systems, named Two-Level Security Enhancement Mechanism or 2L-SEM, in order to ensure the usability and validity of the mobile code through contextual authentication and role analysis. According to the given contextual restrictions, 2L-SEM can filtrate the illegal and invalid mobile codes contained in tags. Finally, a reference architecture and its typical application are given to illustrate the implementation of 2L-SEM in a 2G-RFID system, along with the simulation results to evaluate how the proposed mechanism can guarantee secure execution of mobile codes for the system.
Shot Boundary Detection with Main Color

Zhi Min,Cai An-Ni,

自动化学报 , 2007,
Abstract: Shot boundary detection is one of the critical techniques in video browsing and indexing systems. In this paper, we propose a main color based shot boundary detection algorithm on DC images. We use the bit-rate information to decrease the number of I frames that take part in the shot change detection. Then we obtain local adaptive thresholds based on the main color of a segment of the video sequence. Finally, we detect shot change based on twin-comparison method. Experimental results show that our algorithm can detect shot boundary from a long video sequence with reduced computation, and at the same time solve the problems that are caused by object moving and camera panning in shot change detection.
Min-Hui Cao,Jun Zhu,De-Jiang Ni
Acta Crystallographica Section E , 2008, DOI: 10.1107/s1600536807061521
Abstract: In the crystal structure of the title compound, C23H21N3O2S, all ring atoms of the imidazo[1,2-a]benzothieno[3,2-d]pyrimidine system are essentially coplanar and the phenyl ring is twisted with respect to it [dihedral angle = 72.60 (9)°]. The crystal packing is mainly governed by C—H...π hydrogen bonds and intermolecular π–π interactions, with interplanar distances of 3.54 (1) and 3.56 (1) , and with distances between adjacent ring centroids of 3.72 (1) and 3.80 (1) . The three terminal C atoms of the butyl group are disordered over two positions; the site occupancy factors are ca 0.6 and 0.4.
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