oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 58 )

2018 ( 97 )

2017 ( 97 )

2016 ( 109 )

Custom range...

Search Results: 1 - 10 of 69706 matches for " Mill José Geraldo "
All listed articles are free for downloading (OA Articles)
Page 1 /69706
Display every page Item
Alternate Angiotensin II-Forming Pathways and Their Importance in Physiological or Physiopathological Conditions
Resende Micheline Monteiro de,Mill José Geraldo
Arquivos Brasileiros de Cardiologia , 2002,
Abstract:
Influência do uso de fluoxetina sobre o tempo de corrida em esteira ergométrica em ratos n o treinados Efecto de la fluoxetina sobre el tiempo de ejecución en una cinta en ratas no entrenadas Influence of using fluoxetine on run-time in treadmill in rats un trained
Douglas Colombi Cuquetto,José Geraldo Mill,Fabian Tadeu do Amaral
Revista Brasileira de Educa??o Física e Esporte , 2012, DOI: 10.1590/s1807-55092012000300003
Abstract: Trabalhos de diferentes autores constataram que, um aumento na concentra o de serotonina (5-HT) no cérebro, durante exercício físico intenso e prolongado, está diretamente relacionado a um prejuízo na fun o do Sistema Nervoso Central (SNC), com correspondente desenvolvimento da fadiga e consequente diminui o do desempenho. No presente trabalho, 10 ratos Wistar foram submetidos a sess es de corrida até o esgotamento físico em esteira rolante. Os protocolos experimentais foram divididos em quatro fases: Fase 1 - avalia o do tempo médio de corrida dos animais até o esgotamento físico; Fase 2 - avalia o do tempo médio de corrida dos animais até o esgotamento físico, sob tratamento com fluoxetina; Fase 3 - "washout" de sete dias; Fase 4 - "washout" de 14 dias. Este estudo sugere que a administra o cr nica de fluoxetina aumenta substancialmente o tempo médio de corrida até o esgotamento físico em ratos submetidos a exercício em esteira rolante. Las obras de diferentes autores encontraron que un aumento en la concentración de la serotonina (5-HT) en el cerebro durante el ejercicio intenso y prolongado está directamente relacionado con deterioro de la función del Sistema Nervioso Central (SNC), con el correspondiente desarrollo de la fatiga y su consecuente reducción en el rendimiento. En este estudio, 10 ratas Wistar fueron sometidas a la ejecución de sesiones en una cinta hasta el agotamiento físico. Los protocolos experimentales fueron divididos en cuatro fases: Fase 1 - Evaluación de la carrera media de los animales al agotamiento físico, la Fase 2 - Evaluación de la carrera media de los animales al agotamiento físico, están en tratamiento con fluoxetina, la Fase 3 - "lavado "de siete días; Fase 4 -" lavado "de 14 días. Este estudio sugiere que la administración crónica de fluoxetina incrementa sustancialmente la tarifa media del agotamiento físico en ratas sometidas a ejercicio en una caminadora. Works of different authors have been shown that an increase in the concentration of serotonin (5-HT) in the brain during intense and long-term physical exercise, is directly associated with a harm in the function of the Central Nervous System (CNS), with corresponding development of the fatigue and consequence decrease of the performance. In the present work, 10 rats Wistar were submitted to run-sessions until the exhaustion in treadmill. The experimental protocols were splited in 4 phases: Phase 1: evaluation of the range run-time of the animals until the physical exhaustion. Phase 2: evaluation of the range run-time of the animals until the physical exhaus
Peso dos ventrículos cardíacos determinado em necropsia de indivíduos saudáveis mortos por causas externas
Rodrigues, Sérgio Lamêgo;Pimentel, Enildo Broetto;Mill, José Geraldo;
Arquivos Brasileiros de Cardiologia , 2007, DOI: 10.1590/S0066-782X2007001700001
Abstract: objective:to establish cardiac ventricular weights recorded during the autopsy of healthy individuals who died of external causes, aiming at determining normality patterns in our population. methods:a total of 94 hearts were evaluated at the forensics department of the city of vitória, espírito santo. after the heart removal and resection of the atria and epicardial fat, the right ventricle (rv) and the left ventricle (lv), including the septum, were separated and weighed and the mass was indexed by the height. the kolmogorov-smirnov test was used to test the normality of the distribution. data are presented as means± sd. results:after the exclusion of 12 hearts (possible cardiovascular disease detected post-mortem) 82 hearts were examined (52 males and 30 females, aged 16-68 yrs, 31±12 yrs). the weight of the lv was 181±25 g and 125±15 g, and the weight of the rv was 54±7 g and 38±6 g; the lv mass indexed by height was 105±14 g/m and 78±8 g/m, for males and females, respectively. the p95 of the lv weight was 218 g and 128 g/m in males and 148 g and 88 g/m in females. no significant correlation between ventricular mass and age was observed. conclusion:the weight of the lv in the males from our sample was higher than that reported in the contemporary literature. our results suggest that the presence of lv hypertrophy can be inferred in the presence of lv mass > 218 g or 128 g/m in males and 148 g or 88 g/m in females.
Associa??o entre a raz?o cintura-estatura e hipertens?o e síndrome metabólica: estudo de base populacional
Rodrigues, Sérgio Lamêgo;Baldo, Marcelo Perim;Mill, José Geraldo;
Arquivos Brasileiros de Cardiologia , 2010, DOI: 10.1590/S0066-782X2010005000073
Abstract: background: hypertension and metabolic syndrome are cardiovascular risk factors associated with increased adiposity. in a previous study, waist-to-stature ratio (wsr) was identified as the best obesity index associated with left ventricular hypertrophy. objective: in this study we compared the ability of this index to identify hypertension and metabolic syndrome with other obesity indexes (body mass index - bmi; waist circumference - wc; and waist-to-hip ratio - whr) by receiver operating characteristic (roc) curve analyses. methods: 1,655 (45.8% men) participants of the monica-who/vitoria project, mean age 45 ± 11 y were investigated. metabolic syndrome prevalence (atp-iii criteria) was 32.9%, hypertension was 42.4% and obesity was 19.2%. results: regarding the ability to identify hypertension, there was a significant wsr superiority in relation to bmi and wc (p < 0.05) regardless of gender, but whr (p > 0.05). in relation to the ability to identify metabolic syndrome, there was a significant wsr superiority in relation to whr in men (p < 0.001), but bmi and wc (p = 0.16 and p = 0.9), respectively. however, in women wsr was significantly superior in relation to whr (p < 0.001) and bmi (p = 0.025), but wc (p = 0.8). the optimal wsr cutoffs are 0.52 and 0.53 for hypertension and 0.53 and 0.54 for metabolic syndrome, for men and women, respectively. conclusion: abdominal obesity, identified by wsr as a surrogate, and not overall obesity (bmi as surrogate), is the simplest and best applicable obesity index associated to hypertension and metabolic syndrome in our population.
Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan
Avanza Jr, Ant?nio Carlos;El Aouar, Lilian Mameri;Mill, José Geraldo;
Arquivos Brasileiros de Cardiologia , 2000, DOI: 10.1590/S0066-782X2000000200001
Abstract: objective: to compare the regression of left ventricular hypertrophy in patients with moderate hypertension treated with enalapril, losartan or a combination of the two drugs at lower doses. methods: patients of both sexes with moderate hypertension confirmed by ambulatory monitoring of arte-rial blood pressure and with left ventricular hypertrophy on echocardiogram were assigned to three groups: enalapril (35 mg/day, n=15), losartan (175 mg/day, n=15) and enalapril+losartan (15 mg+100 mg/day, n=16). the patients received the drugs for 10 months. results: the three therapeutic regimens were equally effective in reducing blood pressure and left ventricular mass index (lvmi, g/m2): 141±3.9 to 123±3.6 in the enalapril group (p<0.05), from 147±3.8 to 133±2.8 in the losartan group (p<0.05), and from 146±3.0 to 116±4.0 in the enalapril+losartan group (p<0.05). however, the percent reduction of lvmi was significantly greater (p<0.01) in the enalapril+losartan group (20.5±5.0%) than in enalapril (12.4±3.2%) and the losartan (9.1±2.1%) groups. normalization of lvmi was obtained in 10 out of the 16 patients who received enalapril+ losartan, in 6 out of the 15 patients who received only enalapril and in 4 out of the 15 patients treated with losartan. conclusion: the combination of an angiotensin-converting enzyme inhibitor and an angiotensin ii receptor antagonist (at1 receptor antagonist) in patients produced an additional effect on the reduction of left ventricular hypertrophy. this finding may depend on a more complete inhibition of the cardiac renin-angiotensin.
Hipertens?o arterial e consumo de sal em popula??o urbana
Bisi Molina,Maria del Carmen; Cunha,Roberto de Sá; Herkenhoff,Luis Fernando; Mill,José Geraldo;
Revista de Saúde Pública , 2003, DOI: 10.1590/S0034-89102003000600009
Abstract: objective: to evaluate the salt intake and urinary na+/k+ ratio in a randomized sample from an ethnically mixed urban population. methods: a randomized residential sample of 2,268 individuals aged 25-64 in vitória, es, was selected, of whom 1,663 (73.3%) reported to the hospital for standardized tests. salt, na+ and k+ intake was estimated from 12-hour urine excretion (7 p.m. to 7 a.m.) and from the monthly salt consumption at home reported in the interview. clinic arterial pressure was measured twice under standard conditions by two trained investigators, using mercury sphygmomanometry. the student t and tukey tests were utilized for statistical analysis. results: urinary na+ excretion was higher in men and individuals of lower socioeconomic level (p<0.000). no difference between ethnic groups was observed. k+ excretion was unrelated to socioeconomic level and ethnicity, but was significantly higher among men (25±18 vs. 22±18 meq/12h; p=0.002). positive linear correlation was observed between urinary na+ excretion and systolic (r=0.15) and diastolic (r=0.19) arterial pressure. hypertensive individuals showed higher urinary na+ excretion and na+/k+ ratio than normotensive individuals. reported salt intake was around 50% of the intake estimated from 12-hour urine collection (around 45% of 24-hour urinary excretion). conclusions: salt intake is strongly influenced by socioeconomic level and may partially explain the higher prevalence of hypertension in lower socioeconomic classes.
Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan
Avanza Jr Ant?nio Carlos,El Aouar Lilian Mameri,Mill José Geraldo
Arquivos Brasileiros de Cardiologia , 2000,
Abstract: OBJECTIVE: To compare the regression of left ventricular hypertrophy in patients with moderate hypertension treated with enalapril, losartan or a combination of the two drugs at lower doses. METHODS: Patients of both sexes with moderate hypertension confirmed by ambulatory monitoring of arte-rial blood pressure and with left ventricular hypertrophy on echocardiogram were assigned to three groups: enalapril (35 mg/day, n=15), losartan (175 mg/day, n=15) and enalapril+losartan (15 mg+100 mg/day, n=16). The patients received the drugs for 10 months. RESULTS: The three therapeutic regimens were equally effective in reducing blood pressure and left ventricular mass index (LVMI, g/m2): 141±3.9 to 123±3.6 in the enalapril group (p<0.05), from 147±3.8 to 133±2.8 in the losartan group (p<0.05), and from 146±3.0 to 116±4.0 in the enalapril+losartan group (p<0.05). However, the percent reduction of LVMI was significantly greater (p<0.01) in the enalapril+losartan group (20.5±5.0%) than in enalapril (12.4±3.2%) and the losartan (9.1±2.1%) groups. Normalization of LVMI was obtained in 10 out of the 16 patients who received enalapril+ losartan, in 6 out of the 15 patients who received only enalapril and in 4 out of the 15 patients treated with losartan. CONCLUSION: The combination of an angiotensin-converting enzyme inhibitor and an angiotensin II receptor antagonist (AT1 receptor antagonist) in patients produced an additional effect on the reduction of left ventricular hypertrophy. This finding may depend on a more complete inhibition of the cardiac renin-angiotensin.
Hipertens o arterial e consumo de sal em popula o urbana
Bisi Molina Maria del Carmen,Cunha Roberto de Sá,Herkenhoff Luis Fernando,Mill José Geraldo
Revista de Saúde Pública , 2003,
Abstract: OBJETIVO: Avaliar o consumo de sal e a rela o sódio/potássio urinário em amostra randomizada de popula o urbana etnicamente miscigenada. MéTODOS: Foi selecionada uma amostra rand mica de 2.268 residentes de Vitória, ES, entre 25 e 64 anos de idade. Os indivíduos foram escolhidos por amostragem domiciliar realizada em 1999/2000, dos quais 1.663 (73,3%) compareceram ao hospital para a realiza o de exames padronizados. O consumo estimado de sal, Na+ e K+ foi determinado por meio da coleta de urina de 12h no período noturno (19h às 7h) e do gasto mensal de sal domiciliar referido durante a entrevista. A press o arterial clínica foi medida duas vezes por diferentes pesquisadores treinados em condi es padronizadas, usando esfignomam metro de mercúrio. Para análise estatística foram utilizados o teste de Student e o teste de Tukey. RESULTADOS: A excre o urinária de Na+ foi mais alta em homens e em indivíduos de menores condi es socioecon micas (P<0,000). N o foi observada diferen a entre os grupos étnicos. A excre o de K+ n o se relacionou com nível socioecon mico e ra a, mas foi significativamente mais alta entre os homens (25±18 x 22±18 mEq/12h; P=0,002). Foi observada uma correla o linear positiva entre a excre o urinária de Na+ e press o arterial sistólica (r=0,15) e diastólica (r=0,19). Indivíduos hipertensos apresentaram maior excre o urinária de Na+ e rela o Na/K, quando comparados com indivíduos normotensos. O consumo de sal relatado foi aproximadamente 50% do consumo estimado pela excre o urinária de 12h (em torno de 45% da excre o urinária de 24h). CONCLUS ES: A ingest o de sal é fortemente influenciada pelo nível socioecon mico e pode, parcialmente, explicar a alta prevalência de hipertens o arterial nas classes socioecon micas mais baixas.
Revis?o dos critérios de Sokolow-Lyon-Rappaport e cornell para hipertrofia do ventrículo esquerdo
Rodrigues, Sérgio Lamêgo;D?Angelo, Lílian;Pereira, Alexandre Costa;Krieger, José Eduardo;Mill, José Geraldo;
Arquivos Brasileiros de Cardiologia , 2008, DOI: 10.1590/S0066-782X2008000100008
Abstract: background: electrocardiographically-detected left ventricular hypertrophy (lvh) is a strong predictor of cardiovascular morbidity and mortality. objective: to assess the performance of the sokolow-lyon-rappaport (slr) and cornell voltage criteria in a population sample regarding the diagnosis of lvh on echocardiogram (echo). methods: a total of 641 out of the 682 participants of the second phase of the monica-vitória project were assessed using electrocardiogram and echocardiogram. a subgroup of healthy individuals (n=269) was used to generate reference values of lv mass (lvm). sensitivities and specificities of the electrocardiographic criteria were determined by the roc (receptor-operator characteristics) curve in relation to the diagnosis of lvh, as defined by the internal echocardiographic criterion (lvm > 48 and 46 g/m2.7 for males and females, respectively). results: the prevalence of lvh as detected by echo was 23.7% in the total sample, in which 49% of the individuals were hypertensive. the cornell criterion showed a better association with the lvm as estimated by echo (r= 0.37, p < 0.01) than the slr criterion (r= 0.19) as well as a better performance in the analysis of the area under the roc curve. the new cut-off points for the internally-defined cornell voltage criterion (2.3 mv for males and 1.9 mv for females) showed an acceptable combination of sensitivity (22.5 and 28% for males and females, respectively), with a high specificity (95%). conlusion: the classic slr and cornell voltage criteria showed a low performance in relation to lvh as detected by the echo. however, this accuracy may be improved by using the cornell voltage criteria defined in the present study.
Risco cardiovascular em vegetarianos e onívoros: um estudo comparativo
Teixeira, Rita de Cássia Moreira de Almeida;Molina, Maria del Carmen Bisi;Zandonade, Eliana;Mill, José Geraldo;
Arquivos Brasileiros de Cardiologia , 2007, DOI: 10.1590/S0066-782X2007001600005
Abstract: background: clinical and epidemiological studies have demonstrated a strong association between eating habits and chronic diseases, particularly cardiovascular events, although not all the mechanisms of action are understood. objective: to describe and analyze the cardiovascular risk (cvr) in vegetarians and omnivores residing in greater vitória, state of espírito santo, brazil, in the age range from 35 to 64 years. methods: to evaluate cvr in the groups, a historical cohort study with 201 individuals was conducted. sixty seven individuals who had been following a vegetarian diet for at least five years, and who were from greater vitória, as well as 134 omnivores participating in the monica project/vitória matched for socioeconomic class, gender, age and race were included. biochemical and hemodynamic measurements were obtained in the cardiovascular investigation clinic of ufes. for comparison of proportions, the c2 test was used, and the prevalence ratio was calculated. the cvr was calculated using the framingham algorithm for the group as a whole, and for separate genders. results: the mean age of the group was 47±8 years and the mean duration of vegetarianism was 19±10 years; the lacto-ovo vegetarian diet was followed by 73% of the vegetarians. blood pressure, fasting plasma glucose, total cholesterol, ldl-c, and triglycerides were lower among vegetarians (p<0.001). hdl-c levels were not different between the groups. according to the framingham algorithm, vegetarians had a lower cvr (p<0.001). conclusion: unbalanced omnivorous diet with excess animal protein and fat may be implicated, to a great extent, in the development of noncommunicable diseases and conditions, especially in the cvr.
Page 1 /69706
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.