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A Functional Architecture of Optic Flow in the Inferior Parietal Lobule of the Behaving Monkey
Milena Raffi, Ralph M. Siegel
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000200
Abstract: The representation of navigational optic flow across the inferior parietal lobule was assessed using optical imaging of intrinsic signals in behaving monkeys. The exposed cortex, corresponding to the dorsal-most portion of areas 7a and dorsal prelunate (DP), was imaged in two hemispheres of two rhesus monkeys. The monkeys actively attended to changes in motion stimuli while fixating. Radial expansion and contraction, and rotation clockwise and counter-clockwise optic flow stimuli were presented concentric to the fixation point at two angles of gaze to assess the interrelationship between the eye position and optic flow signal. The cortical response depended upon the type of flow and was modulated by eye position. The optic flow selectivity was embedded in a patchy architecture within the gain field architecture. All four optic flow stimuli tested were represented in areas 7a and DP. The location of the patches varied across days. However the spatial periodicity of the patches remained constant across days at ~950 and 1100 μm for the two animals examined. These optical recordings agree with previous electrophysiological studies of area 7a, and provide new evidence for flow selectivity in DP and a fine scale description of its cortical topography. That the functional architectures for optic flow can change over time was unexpected. These and earlier results also from inferior parietal lobule support the inclusion of both static and dynamic functional architectures that define association cortical areas and ultimately support complex cognitive function.
Experiences with waterjet hydrosurgery system in wound debridement
Raffi Gurunluoglu
World Journal of Emergency Surgery , 2007, DOI: 10.1186/1749-7922-2-10
Abstract: The Versajet? Hydrosurgery System utilizes a reusable power console with foot pedal activation, disposable handpiece and tubing assembly in conjunction with sterile saline and standard waste receptacle. The purpose of this paper is to report our experiences with this instrument in debridement of a variety of wounds prior to final reconstructive surgery. Technical details and pitfalls are discussed to facilitate clinical use.Efficient, safe and fast debridement was achieved in all patients using the hydrosurgery system. The actual time the hydrosurgery system was used for debridement averaged as 15.5 minutes. In ten patients, an adequately debrided wound bed was achieved with a single operative procedure, in four patients; two stages were required prior to reconstructive surgery. In one patient with recurrent sacral-iscial pressure sore, two debridements were carried out followed by long term vacuum assisted closure. The postoperative course was uneventful in all patients, but in three with a minor breakdown of the skin graft, which eventually healed with no surgical intervention.As a result of our clinical experience, the Versajet? enables surgeon to precisely target damaged and necrotic tissue and spare viable tissue. This modality may be a useful alternative tool for soft tissue debridement in certain cases. However, further studies are required to investigate its cost-effectiveness in wound management.Surgical debridement of necrotic tissue is an essential part of wound care prior to any reconstructive options. Sharp techniques utilized for this purpose have been the mainstay and are commonly used in combination with pulsed lavage and/or irrigation.Recently, a new device, the Versajet? Hydrosurgery system, has been described for debridement. The Versajet? hydrosurgery system utilizes high fluid technology for wound debridement. To date, few papers evaluating its role have been published in the literature [1-4]. The purpose of this paper is to report our experienc
Latino, ebraico e volgare illustre: la questione della nobiltà della lingua nel De Vulgari Eloquentia di Dante
Alessandro Raffi
Studi Linguistici e Filologici Online , 2004,
Abstract: In his De vulgari eloquentia (1306) Dante deals with the twofold problem of the origin of language and of the primary structure of the language of Adam, which Dante, such as everyone in the medieval period, identified as Hebrew. The Hebrew structural features give the normative paradigm for the elaboration of a taxonomy of the historical languages and of the Italian dialects, subdivided on the ground of their nobility . In such context, he also theorizes about the connection between the development of the job division and the linguistic differentiation in the mankind, starting from an unheard-of reading of the biblical episode of the tower of Babel. Dante s thought is particularly concerned with the difference between forma locutionis (comparable to Saussure s langue) and actus locutionis (comparable to Saussure s parole). Comparing Hebrew, Latin and the Illustrious Vulgar Language , Dante outlines a doctrine where the poetic language is interpreted as an attempt to take back the historical idioms to the nobility which was prerogative of the Edenic language.
On Some Basic Concepts of Genetic Algorithms as a Meta-Heuristic Method for Solving of Optimization Problems  [PDF]
Milena Bogdanovi?
Journal of Software Engineering and Applications (JSEA) , 2011, DOI: 10.4236/jsea.2011.48055
Abstract: The genetic algorithms represent a family of algorithms using some of genetic principles being present in nature, in order to solve particular computational problems. These natural principles are: inheritance, crossover, mutation, survival of the fittest, migrations and so on. The paper describes the most important aspects of a genetic algorithm as a stochastic method for solving various classes of optimization problems. It also describes the basic genetic operator selection, crossover and mutation, serving for a new generation of individuals to achieve an optimal or a good enough solution of an optimization problem being in question.
The Importance of Health Records  [PDF]
Milena Marini?
Health (Health) , 2015, DOI: 10.4236/health.2015.75073
Abstract: Health records have played an increasingly important role throughout history as an important legal document for the exercise of individuals’ rights. However, domestic legislation fails to define health records as a legally important collection of health data and documents. Recording facts and storing legally important documents are therefore the tasks of the operator. Using the prescriptive method we will determine which laws are governing the management of medical records, their safety and accessibility. Based on the descriptive method, we will describe the process of handling health records by the provider of health treatment, focusing on exposed regulatory gaps in the area of the protection of the rights of an individual. Through the analysis of the laws governing the management of health records, even after death and operator terminating the service, we will carry out inductive reasoning and provide conclusions regarding the attitude towards health records. Considering different results we can conclude that health information, especially documents relevant to the protection of individual’s rights, is not transparent. Above all, the documents in the collection are not recorded properly, thus allowing for their removal. Even the transfer of health records by the provider of health treatment is not defined, which could result in the disposal of the entire health documentation.
Travel Time Estimation Using Floating Car Data
Raffi Sevlian,Ram Rajagopal
Computer Science , 2010,
Abstract: This report explores the use of machine learning techniques to accurately predict travel times in city streets and highways using floating car data (location information of user vehicles on a road network). The aim of this report is twofold, first we present a general architecture of solving this problem, then present and evaluate few techniques on real floating car data gathered over a month on a 5 Km highway in New Delhi.
Feeder Topology Identification
Raffi Sevlian,Ram Rajagopal
Computer Science , 2015,
Abstract: Advanced control of distributed energy resources at the consumer level requires full situational awareness of the the distribution system. One important problem is that of feeder topology identification, due to changing switch configurations, given a sparse number of measurements. We formulate the problem for residential feeders as a spanning tree identification problem over a general graph. Given a set of power flow measurements and load pseudo measurements, we show that the underlying graph structure is crucial in defining identifiability of the correct spanning tree on the graph. First we solve the deterministic case of known true loads and measured power flow. We show that the placement of sensors on the network alone determine whether the set of spanning trees can be correctly identified. In the stochastic case where loads are in the form of noisy forecasts, we present a locally optimal sensor placement algorithm.
Short Term Electricity Load Forecasting on Varying Levels of Aggregation
Raffi Sevlian,Ram Rajagopal
Statistics , 2014,
Abstract: We propose a simple empirical scaling law that describes load forecasting accuracy at different levels of aggregation. The model is justified based on a simple decomposition of individual consumption patterns. We show that for different forecasting methods and horizons, aggregating more customers improves the relative forecasting performance up to specific point. Beyond this point, no more improvement in relative performance can be obtained.
Multiple choices for HIV therapy with integrase strand transfer inhibitors
Raffi Francois,Wainberg Mark A
Retrovirology , 2012, DOI: 10.1186/1742-4690-9-110
Abstract: Two integrases inhibitors, raltegravir and elvitegravir, have now been approved by regulatory agencies for use in the treatment of HIV-infected patients; and the approval of a third such drug, dolutegravir, is expected during 2013 on the basis of several phase 3 clinical trials. The advent of this new class of antiretroviral (ARV) medications represents a major advance in the management of HIV infection, and each of these three drugs can be expected to continue to be an important component of ARV combination regimens.
Skin avulsion injury during endotracheal tube extubation – case report of an unusual complication
Berkhan Yilmaz, Kutay Colakoglu, Raffi Gurunluoglu
Patient Safety in Surgery , 2008, DOI: 10.1186/1754-9493-2-12
Abstract: Endotracheal tubes that are used for airway maintenance must be securely placed and fixated in order to avoid complications such as accidental extubations, tracheal injuries or swallowed endotracheal tube [1].We report a 75-year-old patient in whom a full-thickness skin avulsion injury occurred during extubation due to securing tape used to fixate the endotracheal tube. In addition, plausable reasons of this rare complication are discussed.A 75-year-old Caucasian female was admitted to the emergency department after falling down the stairs. On examination, there was a severe tenderness on her right hip and bruises on her both cheeks, on right malar region and dorsal region of her left forearm. No open wound was detected. Her skin turgor and tonus were seriously decreased. Her medical history was normal. Radiological studies showed a right hip fracture. A total hip joint replacement as an emergency procedure was planned by orthopedics. The patient was intubated by an anesthesiologist with an endotracheal tube and the tube was fixated and secured to the patient's right cheek by using tapes (Hypafix?;BSN medical GmgH & Co. KG, Hamburg, Germany) in a standard fashion [2] (Fig. 1). During a standard extubation, a piece of full-thickness skin avulsed as attached to the securing tape from the patient's right cheek. Plastic surgery department was urgently consulted. The skin graft was removed from the tape, and it was preserved in a gauze soaked into saline (Fig. 2). On examination, a full-thickness skin loss 3 × 8 cm in size was detected on the right cheek (Fig. 3). The avulsed skin was sutured back to its original place by 5/0 plain catgut sutures under sedation and local anesthesia. Being aware of the patient's fragile skin, the tie-over sutures used routinely to immobilize the graft were passed deep enough to avoid undue tears of the overlying epithelium. Seven days later after an uneventful healing period, the tie-over dressing was opened and the graft was found to hea
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