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Search Results: 1 - 10 of 21459 matches for " Miguel; Vazquez Rodriguez "
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Reflexiones sobre los Tribunales de las Oposiciones Universitarias
Vazquez Mata,Guillermo; Rodriguez Castro,Felipe; Alcaraz Sala,Rodolfo; Novoa Mogollon,Francisco Javier; Gurgui Ferrer,Mercedes; Santos Rodriguez,Miguel; Vazquez Rodriguez,Juan José;
Educación Médica , 2006, DOI: 10.4321/S1575-18132006000300003
Abstract: medicine is undergoing clinical, therapeutic and technological changes, and this is coinciding with demographic, cultural and epidemiological variations. these factors, and the speed with which innovations occur in all fields, requires a rethink of doctors' training, not only during their initial university studies but also throughout their professional life. those responsible for appointing medical school lecturers must take into account all these aspects in order to ensure that the teaching staff of the future will transmit these values to students. in turn, candidates must be aware of the key aspects around which they should develop their curriculum.
Application of GPUs for the Calculation of Two Point Correlation Functions in Cosmology
Rafael Ponce,Miguel Cardenas-Montes,Juan Jose Rodriguez-Vazquez,Eusebio Sanchez,Ignacio Sevilla
Physics , 2012,
Abstract: In this work, we have explored the advantages and drawbacks of using GPUs instead of CPUs in the calculation of a standard 2-point correlation function algorithm, which is useful for the analysis of Large Scale Structure of galaxies. Taking into account the huge volume of data foreseen in upcoming surveys, our main goal has been to accelerate significantly the analysis codes. We find that GPUs offer a 100-fold increase in speed with respect to a single CPU without a significant deviation in the results. For comparison's sake, an MPI version was developed as well. Some issues, like code implementation, which arise from using this option are discussed.
Garlic and Onion Attenuates Vascular Inflammation and Oxidative Stress in Fructose-Fed Rats
Marcela Alejandra Vazquez-Prieto,Cecilia Rodriguez Lanzi,Carina Lembo,Claudio Rómulo Galmarini,Roberto Miguel Miatello
Journal of Nutrition and Metabolism , 2011, DOI: 10.1155/2011/475216
Abstract: This study evaluates the antioxidant and the anti-inflammatory properties of garlic (G) and onion (O) in fructose-fed rats (FFR). Thirty-day-old male Wistar rats were assigned to control (C), F (10% fructose in drinking water), F
Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease
Miguel A Gonzalez-Gay, Carlos Gonzalez-Juanatey, Tomas R Vazquez-Rodriguez, Javier Martin, Javier Llorca
Arthritis Research & Therapy , 2008, DOI: 10.1186/ar2409
Abstract: We recently reported [2] that carotid artery IMT had good ability to predict development of cardiovascular events over a 5-year period of follow up in 47 patients with RA without clinically evident cardiovascular disease at the time of evaluation by carotid ultrasonography. In our study carotid IMT, categorized in quartiles, was strongly associated with cardiovascular events; specifically, none of the RA patients with carotid IMT less than 0.77 mm suffered cardiovascular events. However, six of the 10 patients with carotid IMT greater than 0.91 mm experienced cardiovascular events. When logistic regression models were performed, carotid IMT at the time of ultrasonographic study had high power to predict development of cardiovascular events over the 5-year period of follow up. Although the area under the receiver operating characteristic curve was 0.86 when using age at the onset of the study, it was greater in models that included carotid IMT. In this regard, the area under the receiver operating characteristic curve was 0.93 for a model that included only carotid IMT. Based on these findings, we propose that ultrasonographic assessment of the carotid artery should be performed in all patients with RA in order to identify the subgroup of patients at high risk for cardiovascular complications.In the same editorial, Veldhuijzen van Zanten and Kitas [1] emphasize that endothelial function is highly dependent on current levels of inflammation. We agree entirely with the authors on this point; we observed endothelial dysfunction in patients with biopsy-proven giant cell arteritis (GCA) – an inflammatory disease that involves large and middle-sized blood vessels. However, steroid therapy was able to improve endothelial function. This effect was observed when laboratory markers of inflammation returned to normal levels [3]. Whether normalization of endothelial function might lead to 'protection' against development of accelerated atherosclerosis in chronic inflammatory dis
Garlic and Onion Attenuates Vascular Inflammation and Oxidative Stress in Fructose-Fed Rats
Marcela Alejandra Vazquez-Prieto,Cecilia Rodriguez Lanzi,Carina Lembo,Claudio Rómulo Galmarini,Roberto Miguel Miatello
Journal of Nutrition and Metabolism , 2011, DOI: 10.1155/2011/475216
Abstract: This study evaluates the antioxidant and the anti-inflammatory properties of garlic (G) and onion (O) in fructose-fed rats (FFR). Thirty-day-old male Wistar rats were assigned to control (C), F (10% fructose in drinking water), F+T (tempol 1?mM as control antioxidant), F+G, and F+O. Aqueous G and O extracts were administered orally in doses of 150 and 400?mg/kg/d respectively, and along with tempol, were given during the last 8 weeks of a 14-week period. At the end of the study, FFR had developed insulin resistance, aortic NADPH oxidase activity, increased SBP, plasma TBARS and vascular cell adhesion molecule-1 (VCAM-1) expression in mesenteric arteries, and a decrease in heart endothelial nitric oxide synthase (eNOS). Garlic and onion administration to F rats reduced oxidative stress, increased eNOS activity, and also attenuated VCAM-1 expression. These results provide new evidence showing the anti-inflammatory and antioxidant effect of these vegetables. 1. Introduction Metabolic syndrome (METS), characterized by hypertension, hyperlipidemia, diabetes mellitus, and obesity is an important risk factor for cardiovascular disease [1]. One of the most important causes that contribute to the growing worldwide prevalence of METS, obesity, and type 2 diabetes is the change of dietary habits principally due to the increased intake of simple sugars, mainly fructose, commonly used in the food industry and sugar-sweetened drinks [2]. Feeding carbohydrate-enriched diets to normal rats has been shown to induce insulin resistance and hyperinsulinemia associated with an elevation of systolic blood pressure (SBP) [3]. Fructose-fed rats (FFRs) provide a model of dietary-induced insulin resistance, which has been used to assess the pathophysiological mechanisms of the metabolic and cardiovascular changes associated with METS [4, 5]. Endothelial dysfunction is also associated with this experimental model [6]. Our group previously reported a decrease of the endothelial nitric oxide synthase activity (eNOS) at cardiovascular level, and an increase in oxidative stress and vascular alterations [5, 7]. The major sources of reactive oxygen species (ROS) in vascular tissue are membrane-associated NAD(P)H oxidases [8]. An increase in ROS has been implicated as an important mechanism contributing to endothelial dysfunction and to the pathogenesis of many cardiovascular diseases and their risk factors like METS [9]. ROS induce the expression of different molecules in the endothelial cell surface such as vascular cell adhesion molecule-1 (VCAM-1), which stimulates monocyte binding
Population Fluctuation of Horn Fly (Haematobia irritans) in an Organic Dairy Farm
Ema Maldonado-Siman,Pedro Arturo Martinez-Hernandez,Hector Sumano-Lopez,Carlos Cruz-Vazquez,Raymundo Rodriguez de Lara,Miguel Angel Alonso-Diaz
Journal of Animal and Veterinary Advances , 2012,
Abstract: Haematobia irritans (Linnaeus) is an economically important pest of livestock. Its infestation causes significant losses in meat and milk production, as well as damaging skin quality. Organic livestock production has increased because of market demands with emphasis on high standards in animal health and welfare and therefore, good production practices are warranted. To achieve this goal, epidemiological studies are needed to devise integrated pest management programs capable of reducing parasite burden to an economic threshold for organic dairy production. Consequently, the objective of the study was to determine Haematobia irritans population seasonality and to relate these changes with weather factors. Field phase was developed in an organic dairy farm located in a Mexican temperate climate throughout a 2 years period (2003 and 2004). Weekly horn fly counts and 4 weathers parameters were measured and correlated for each year and years combined. Flies were found on cattle year round in both years the highest loads were 130 flies cow-1 in 2003 and 255 flies cow-1 in 2004 both in summer. Rainfall showed the highest correlation (r = 0.68) with horn fly in 2004 and for years combined (r = 0.67), while in 2003, it was relative humidity with a correlation of r = 0.75. The lower counts of horn flies on cattle found in winter and early spring were associated with a drier environment and relative lower air temperatures; however, none of the weather factors were severe enough to achieve a complete elimination of flies, the year round presence and summer peaks of flies can be a constraint to animal welfare and production. It was concluded that yearly fly population changes can be associated to weather factors and mild temperatures in winter allows finding flies on cattle year-round.
A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis
Rogelio Palomino-Morales, Carlos Gonzalez-Juanatey, Tomas R Vazquez-Rodriguez, Luis Rodriguez, Jose A Miranda-Filloy, Benjamin Fernandez-Gutierrez, Javier Llorca, Javier Martin, Miguel A Gonzalez-Gay
Arthritis Research & Therapy , 2010, DOI: 10.1186/ar2989
Abstract: Six hundred and twelve patients fulfilling the 1987 American College of Rheumatology classification criteria for RA, seen at the rheumatology outpatient clinics of Hospital Xeral-Calde, Lugo and Hospital San Carlos, Madrid, were studied. Patients and controls (n = 865) were genotyped using predesigned TaqMan SNP genotyping assays.No significant differences in allele or genotype frequencies for the MTHFR gene polymorphisms between RA patients and controls were found. Also, no association between the MTHFR 677 C>T polymorphism and CV events or endothelial dysfunction was observed. However, the MTHFR 1298 allele C frequency was increased in patients with CV events after 5 years (38.7% versus 30.3%; odds ratio = 1.45; 95% confidence interval = 1.00 to 2.10; P = 0.04) and 10 years (42.2% versus 31.0%; odds ratio = 1.62; 95% confidence interval = 1.08 to 2.43; P = 0.01) follow up. Moreover, patients carrying the MTHFR 1298 AC and CC genotypes had a significantly decreased flow-mediated endothelium-dependent vasodilatation (4.3 ± 3.9%) compared with those carrying the MTHFR 1298 AA genotype (6.5 ± 4.4%) (P = 0.005).Our results show that the MTHFR 1298 A>C gene polymorphism confers an increased risk for subclinical atherosclerosis and CV events in patients with RA.Patients with rheumatoid arthritis (RA) have increased risk of cardiovascular (CV) disease due to accelerated atherosclerosis [1]. Besides classic CV risk factors, a number of nontraditional CV risk factors have also been implicated in the elevated CV mortality observed in these patients [2].In this regard, chronic inflammation and the genetic background increase the risk of CV events in RA regardless of the presence of traditional CV risk factors [3]. Hyperhomocysteinemia has been found to be an independent nontraditional risk factor for CV disease, including coronary disease, in the general population [4]. Homocysteine is an intermediary amino acid formed during the conversion of methionine to cysteine. High ele
Canonical extension of submanifolds and foliations in noncompact symmetric spaces
Miguel Dominguez-Vazquez
Mathematics , 2014,
Abstract: We propose a method to extend submanifolds, singular Riemannian foliations and isometric actions from a boundary component of a noncompact symmetric space to the whole space. This extension method preserves minimal submanifolds, isoparametric foliations and polar actions, among other properties. One of the several applications yields the first examples of inhomogeneous isoparametric hypersurfaces in noncompact symmetric spaces of rank at least two.
Isoparametric foliations on complex projective spaces
Miguel Dominguez-Vazquez
Mathematics , 2012,
Abstract: Irreducible isoparametric foliations of arbitrary codimension q on complex projective spaces CP^n are classified, except if n=15 and q=1. Remarkably, there are noncongruent examples that pull back under the Hopf map to congruent foliations on the sphere. Moreover, there exist many inhomogeneous isoparametric foliations, even of higher codimension. In fact, every irreducible isoparametric foliation on the complex projective n-space is homogeneous if and only if n+1 is prime. The main tool developed in this work is a method to study singular Riemannian foliations with closed leaves on complex projective spaces. This method is based on certain graph that generalizes extended Vogan diagrams of inner symmetric spaces.
Asymptotic Distribution Of The Roots Of The Ehrhart Polynomial Of The Cross-Polytope
Miguel Rodriguez
Mathematics , 2010,
Abstract: We use the method of steepest descents to study the root distribution of the Ehrhart polynomial of the $d$-dimensional cross-polytope, namely $\mathcal{L}_{d}$, as $d\rightarrow \infty$. We prove that the distribution function of the roots, approximately, as $d$ grows, by variation of argument of the generating function $\sum_{m\geq 0}\mathcal{L}_{d}(m)t^{m+x-1}=(1+t)^{d}(1-t)^{-d-1}t^{x-1}$, as $t$ varies appropriately on the segment of the imaginary line contained inside the unit disk.
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