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Search Results: 1 - 10 of 466417 matches for " Michelle A Vasconcelos "
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Home caregivers knowledge and practices of pressure ulcer: qualitative study.
Maria de LB da Silva,Michelle A Vasconcelos,Roberlandia E Lopes,Maria CGA Lima
Online Brazilian Journal of Nursing , 2009,
Abstract: The pressure ulcer (PU) emerges for mobility restrictions and patients with these limitations need a caretaker. The study is of exploratory-descriptive type, with qualitative approach which objectives were: to draw the home caretaker's profile; to evaluate the knowledge of these ones on PU; to identify the preventions completion by them and the factors that hinder and facilitate when caring, it was developed with seven caretakers. Data were collected through semi-structured interviews with seven caregivers of patients with pressure ulcers, being analyzed in accordance with the theme analysis approach. The study revealed that most of the caretakers were women and daughters with knowledge deficit about PU prevention. As an obstacle of caring was mentioned the weight and as facilitators love and affection. We concluded that as bedridden the patient requires caring related to PU prevention, nursing fits there to evaluate and to manage the patients' needs and the caretakers, which will contribute to the promotion of qualified attendance, and will make possible for the caretaker to be autonomous in the completion of the cares.
Pregnancy rates and predictors in women with HIV/AIDS in Rio de Janeiro, Southeastern Brazil
Friedman,Ruth Khalili; Bastos,Francisco I; Leite,Iuri Costa; Veloso,Valdiléa G; Moreira,Ronaldo I; Cardoso,Sandra W; Andrade,?ngela C Vasconcelos de; Sampaio,Michelle Cristina; Currier,Judith; Grinsztejn,Beatriz;
Revista de Saúde Pública , 2011, DOI: 10.1590/S0034-89102011000200016
Abstract: objective: to assess incidence and predictors of first pregnancy among women with hiv/aids. methods: prospective cohort study was conducted in rio de janeiro, southeastern brazil, between 1996 and 2003. this study comprised 225 women with hiv/aids followed up until their first pregnancy or first censored event (hysterectomy, tubal ligation, menopause, 50 years of age, loss to follow-up, death or the end of december 2003). pregnancy and abortion rates were estimated, and cox proportional hazards models were used to identify baseline characteristics associated with pregnancy risk. results: the women were followed up for 565 person/years with a median follow-up of 3 years per women. the mean age was 32 years (sd: 7), and 54.7% were white. there were 60 pregnancies in 39 women, and 18 were terminated (induced abortions), accounting for a rate of 6.9% and 2.1% women/year, respectively. repeated pregnancies occurred in 33.3% of the women (13/39). higher pregnancy risk was seen among younger women (hr=3.42; 95%ci: 1.69;6.95) and those living with their partners (hr=1.89; 95%ci: 1.00;3.57). lower pregnancy risk was associated with higher education level (hr=0.43; 95%ci: 0.19;0.99) and use of antiretroviral therapy (hr=061; 95%ci: 0.31;1.17). conclusions: lower pregnancy rates were found in our cohort than in the general population. sociodemographic characteristics should be taken into consideration in the management of reproductive health in hiv-positive childbearing age women. reproductive and family planning counseling must be incorporated into hiv/aids programs for women to help preventing hiv transmission to their partners and offspring.
Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
Bomfim,Kátia Michelle dos Anjos; Garcia,Carlos Alexandre Borges; Reis,Francisco Prado; Palmeira,José Arnaldo Vasconcelos; Scher,Ricardo; de Lucca Júnior,Waldecy; Arag?o,José Adeval; Vasconcelos,Francis Lima; Albuquerque Júnior,Ricardo Luiz Cavalcanti; Feitosa,Vera Lúcia Corrêa;
International Journal of Morphology , 2012, DOI: 10.4067/S0717-95022012000100021
Abstract: lead is one of the heavy metals most used in industry. poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. lead is highly toxic and can compromise the structural and functional patterns of organs and systems. the aim of this study was to examine the lungs and kidneys of fetuses from female wistar rats exposed to lead acetate. in this study, the lungs and kidneys of 20 fetuses from female rats that had previously been treated with lead acetate were dissected, fixed, embedded in paraffin and stained with hematoxylin and eosin. macroscopic changes to the shape, color and consistency of organs from fetuses treated with this heavy metal were observed, in comparison with organs from control fetuses. microscopic lesions characterized by vascular sclerosis, cell atrophy or hyperplasia, progressive interstitial fibrosis, inclusion bodies containing lead acetate and glomerular sclerosis were found in the kidneys. the lesions found in the lungs consisted of destructuring of the parenchyma, impregnation with lead acetate, formation of fibrosis, extravasation of vascular fluids, reduction of the alveolar spaces and formation of alveolar edema. these changes were correlated with the level of lead acetate absorption, as determined using atomic spectrophotometry.
Pólipos e Cancro do Cólon e Recto
Teixeira,A. Vasconcelos;
Arquivos de Medicina , 2009,
Abstract: introduction: colorectal cancer (crc) in non-smoking patients of both genders is the most frequent in usa, australia, new zeland and western europe. in portugal the crc is the leading cause of death from malignant tumor.the most common initial symptoms are rectal hemorrhage and changes in the intestinal transit. the survival rate within the ?rst ?ve years can be superior to 90%, providing the diagnosis is made at an early stage. therefore, screening is very important and should be based on risk grading. since most crc (95%) originate from adenoma - precursor lesion-, removing the adenomatous polyps reduces the cases of crc in 76% to 96%. consequently, colonoscopy plays an important role in polyps diagnosis and their removal by polypectomy. however, this tecnique has got some restrictions and complications, wich has led to new diagnosis and therapeutic methods. it is importantto follow the patients with polyps according to quite consensual guidelines. methods: between june 2004 and october 2008 1114 cases for colonoscopy were referred to us. after appropriate preparation, we have done the total colonoscopy (observed cecum in 95% of the cases), under anesthesia with propofol. results: polyps were diagnosed in 32.3% of the cases and 205 polypectomies were done. approximately 54% of the polyps were adenomatous. high-grade dysplasia was diagnosed in 5 cases and adenocarcinoma in 3 cases. the treatment of these cases requires collaboration with surgery. conclusions: the crc is a serious public health problem. colonoscopy is considered to be the gold standard method in screening the crc. it provides the opportunity to detect the pre-malignant lesion - adenoma- and its removal in good time, in spite of the limits of our knowledge about the biology of the polyps and of the crc. the results by different authors reveals the importance of the colonoscopy with polypectomy in crc prevention.
Endomycorrhizal Fungi and Opuntia ficus-indica Seed Germination on a Lunar Regolith Simulant  [PDF]
Gertrud Konings-Dudin, Michelle J. Butcher, Jesus A. Castor-Macías, Benjamin Kohanloo, Michelle Garcia
Advances in Microbiology (AiM) , 2014, DOI: 10.4236/aim.2014.410068

Endomycorrhizal fungi play an important role in the survival of plants on poor soils. Planting seeds into lunar soil at a lunar colony will be a challenge for seeds of any plant. The seeds will need a special microbial “tool kit” that will help them germinate and the young seedlings establish themselves. In this study, seeds of the prickly pear cactus, Opuntia ficus-indica, were chosen to examine the presence of fungus spores in the soil, inside the seeds and after germination in the rhizosphere, roots and other tissues of the young seedlings. The nutrient poor lunar regolith simulant JSC-1A was used as autoclaved or untreated growth medium. The mycorrhizal fungus Trichoderma viride was predominantly identified on the roots of new seedlings. This fungus also demonstrated the strongest effect on the germination rate of the seeds in comparison with other fungi isolated from the rhizosphere of Opuntia plants. T. viride was not detected within seeds and also not within seedlings, besides the root tips, whereas an arbuscular mycorrhizal Glomus species was seed-borne and present throughout most of the seedling. A close association between T. viride and a Glomus species associated with O. ficus-indica

Michelle Mojica Nore?a
El Agora USB , 2011,
Abstract: El presente artículo presenta resultados de una investigación que busca brindar elementos que den cuenta de la validez o sustento y justificación del apelativo de Terrrorista al grupo aramado de las FARC – EP. grupo insurgente alzado en Armas en Colombia y protagonista del conflicto interno en Colombia ya hace más de 45 a os No solo es importante ver cuál es el contexto en el que surgen estos calificativos, sino sentar las bases para un estudio riguroso del caso apoyándose en datos que confirmen las tesis aquí planteadas.Abstract:This article presents the research results whose aim is to provide elements that report the validity or the support and the justification of the nickname of Terrorist to the FARC - EP group. It is an armed insurgent group in Colombia and main figure of the internal conflict in Colombia for more than 45 years. Not only is it important to see the context in which these nicknames appear, but also to lay the foundations for a rigorous analysis of the case by relying on the data that confirm the theses raised in this study.
Pointing at the moon: teaching and learning without resistance
Michelle A. Massé
ETD : Educa??o Temática Digital , 2011,
Abstract: Teachers often embrace narratives in which students' resistance to our teaching marks repression of the truths delivered by our learned selves. In students' counter-narratives, the tale of resistance can morph into one about principled refusal of powerful figures trying to force them into stances not their own. Both stories have strong temporal dimensions in which closure, even if it comes decades later, reveals that one party or the other was indeed influenced and changed, whether or not that change was evident at semester's end. My interest here is in how to question premature closure and how to work instead within the suspended liminal time of knowing/not knowing for teacher and student.
A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis
Crystal Y. Chen equal contributor,Dan Huang equal contributor,Richard C. Wang,Ling Shen,Gucheng Zeng,Shuyun Yao,Yun Shen,Lisa Halliday,Jeff Fortman,Milton McAllister,Jim Estep,Robert Hunt,Daphne Vasconcelos,George Du,Steven A. Porcelli,Michelle H. Larsen,William R. Jacobs Jr.,Barton F. Haynes,Norman L. Letvin,Zheng W. Chen
PLOS Pathogens , 2009, DOI: 10.1371/journal.ppat.1000392
Abstract: The role of CD8 T cells in anti-tuberculosis immunity in humans remains unknown, and studies of CD8 T cell–mediated protection against tuberculosis in mice have yielded controversial results. Unlike mice, humans and nonhuman primates share a number of important features of the immune system that relate directly to the specificity and functions of CD8 T cells, such as the expression of group 1 CD1 proteins that are capable of presenting Mycobacterium tuberculosis lipids antigens and the cytotoxic/bactericidal protein granulysin. Employing a more relevant nonhuman primate model of human tuberculosis, we examined the contribution of BCG- or M. tuberculosis-elicited CD8 T cells to vaccine-induced immunity against tuberculosis. CD8 depletion compromised BCG vaccine-induced immune control of M. tuberculosis replication in the vaccinated rhesus macaques. Depletion of CD8 T cells in BCG-vaccinated rhesus macaques led to a significant decrease in the vaccine-induced immunity against tuberculosis. Consistently, depletion of CD8 T cells in rhesus macaques that had been previously infected with M. tuberculosis and cured by antibiotic therapy also resulted in a loss of anti-tuberculosis immunity upon M. tuberculosis re-infection. The current study demonstrates a major role for CD8 T cells in anti-tuberculosis immunity, and supports the view that CD8 T cells should be included in strategies for development of new tuberculosis vaccines and immunotherapeutics.
ALDH1A2 (RALDH2) genetic variation in human congenital heart disease
Marilene Pavan, Viviane F Ruiz, Fábio A Silva, Tiago J Sobreira, Roberta M Cravo, Michelle Vasconcelos, Lívia P Marques, Sonia MF Mesquita, José E Krieger, Ant?nio AB Lopes, Paulo S Oliveira, Alexandre C Pereira, José Xavier-Neto
BMC Medical Genetics , 2009, DOI: 10.1186/1471-2350-10-113
Abstract: One-hundred and thirty-three CHD patients were screened for genetic variation at the ALDH1A2 locus through bi-directional sequencing. In addition, six SNPs (rs2704188, rs1441815, rs3784259, rs1530293, rs1899430) at the same locus were studied using a TDT-based association approach in 101 CHD trios. Observed mutations were modeled through molecular mechanics (MM) simulations using the AMBER 9 package, Sander and Pmemd programs. Sequence conservation of observed mutations was evaluated through phylogenetic tree construction from ungapped alignments containing ALDH8 s, ALDH1Ls, ALDH1 s and ALDH2 s. Trees were generated by the Neighbor Joining method. Variations potentially affecting splicing mechanisms were cloned and functional assays were designed to test splicing alterations using the pSPL3 splicing assay.We describe in Tetralogy of Fallot (TOF) the mutations Ala151Ser and Ile157Thr that change non-polar to polar residues at exon 4. Exon 4 encodes part of the highly-conserved tetramerization domain, a structural motif required for ALDH oligomerization. Molecular mechanics simulation studies of the two mutations indicate that they hinder tetramerization. We determined that the SNP rs16939660, previously associated with spina bifida and observed in patients with TOF, does not affect splicing. Moreover, association studies performed with classical models and with the transmission disequilibrium test (TDT) design using single marker genotype, or haplotype information do not show differences between cases and controls.In summary, our screen indicates that ALDH1A2 genetic variation is present in TOF patients, suggesting a possible causal role for this gene in rare cases of human CHD, but does not support the hypothesis that variation at the ALDH1A2 locus is a significant modifier of the risk for CHD in humans.Congenital heart disease (CHD) was thought to be a multi-factorial, polygenic disease whose genes were as inscrutable as its postulated environmental agents [1]. Now
Trabalho for?ado, tráfico de pessoas e gênero: algumas reflex?es
Vasconcelos, Marcia;Bolzon, Andréa;
Cadernos Pagu , 2008, DOI: 10.1590/S0104-83332008000200004
Abstract: the core of the concept of trafficking in persons, defined in the palermo protocol, is based on the notion of exploitation. this text approaches trafficking in persons as a labor issue with a view to helping clarify this notion. the forced labor concept, formulated by the international labor organization, supports this discussion. this concept is considered in its dialog with gender dimensions and with the supply-demand aspects that steer migratory movements.
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