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Search Results: 1 - 10 of 173706 matches for " Michael V. Maciosek "
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Cholesterol Levels and Statin Use in Patients With Coronary Heart Disease Treated in Primary Care Settings
Patrick J. O’Connor, MD, MPH,Richard J. Gray, MD,Michael V. Maciosek, PhD,Kelly M. Fillbrandt, BS
Preventing Chronic Disease , 2005,
Abstract: Introduction Therapy with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, has proven to be effective in the treatment of lipid disorders. However, statin therapy continues to be underused, even though statins are a relatively safe and well-tolerated class of agents. In this study, we assessed trends in lipid control in patients with heart disease who receive most of their health care in primary care clinics. The objective was to determine whether systems of care implemented within a large medical group are associated with improved treatment and control of dyslipidemia in a high-risk group of coronary heart disease patients. Methods All adults with heart disease in a Minnesota medical group (N = 2947) were identified using diagnosis and procedure codes related to coronary heart disease (sensitivity = 0.85; positive predictive value = 0.89) in 1996. Study subjects were observed from 1995 to 1998. Subjects had a baseline and follow-up test for low-density lipoprotein cholesterol and high-density lipoprotein cholesterol. Changes between baseline and follow-up measurements and trends in the use of statins and other lipid-active agents among the study subjects were analyzed. Results Among 1388 subjects with two or more eligible lipid measurements, mean low-density lipoprotein cholesterol improved from 137.6 mg/dL to 111.0 mg/dL (P < .001), and mean high-density lipoprotein cholesterol improved from 42.3 mg/dL to 46.3 mg/dL (P < .001). The percentage of patients with low-density lipoprotein cholesterol ≤100 mg/dL rose from 12.5% to 39.8% (P < .001), and the percentage with high-density lipoprotein cholesterol ≥40 mg/dL rose from 52.5% to 67.6% (P < .001). In multivariate models, statin use was identified as the main factor that contributed to the improvement in low-density lipoprotein cholesterol (P < .001). Men had greater decreases in low-density lipoprotein cholesterol than women after adjusting for other variables (P < .001). Statin use rose from 24.3% at baseline to 69.6% at follow-up. The statin discontinuation rate was 8.3% for baseline statin users and 12.2% for subjects who used statins at any time during the study period. Conclusion Investment in better heart disease care for patients in primary care clinics led to major improvement in lipid control over 30 months, primarily due to increased statin use. Improvements in low-density lipoprotein cholesterol and high-density lipoprotein cholesterol were sufficient to substantially reduce risk of subsequent major cardiovascular events.
Peak Power Effect on Skin Rejuvenation Using IPL: Lumecca IPL Evaluation  [PDF]
E. V. Ross, Michael Kreindel
Advances in Aging Research (AAR) , 2016, DOI: 10.4236/aar.2016.53008
Abstract: A high peak power IPL system (Lumecca) was tested to determine the correlation between a high peak power and the successful treatment of pigmented and vascular lesions. Short pulse duration in the millisecond range and high peak power of 3.3 kW/cm2 enabled selective and effective destruction, not only of pigment, but also of vessels in a comparable manner to a pulsed dye laser. Only one treatment session at a low fluence (8 - 16 J/cm2) was sufficient to achieve the desired results.
Use of motor learning principles to improve motor adaptation in adult obesity  [PDF]
Simone V. Gill, Michael K. Walsh
Health (Health) , 2012, DOI: 10.4236/health.2012.412A206

Obesity is an epidemic in the United States, and weight loss is key component to overcoming the problem. However, the risk of falling and injury in the obese population may hinder their engagement in the amount and intensity of physical activity needed to lose weight. The risks of falling and injury have been attributed to differences in temporospatial walking parameters, musculoskeletal structure, and cognitive processing: all of which affect the obese population’s ability to adapt while walking. We have proposed that an intervention using motor learning principles with an implicit learning task could improve the adaptive abilities of obese individuals during movement and thus, allow for safer participation in physical activity during weight loss interventions.

Quantum Nature of Distortion and Delay of Satellite Signals II  [PDF]
Gennady V. Golubkov, Michael I. Manzhelii, Lev V. Eppelbaum
Positioning (POS) , 2018, DOI: 10.4236/pos.2018.93004
Abstract: A detailed analysis of the influence of Rydberg states to the behavior of GPS satellite signals in the D and E atmospheric layers has been carried out. It is demonstrated that these states are the main reason for the GPS signal distortion. It is shown that the behavior of satellite signals is associated with the spectral characteristics of the UHF radiation of the Rydberg states depending on the geomagnetic conditions of ionosphere. The foundations of the quantum theory of distortion and delay of GPS satellite signal propagation through D and E atmospheric layers are analyzed and expounded. The problem reduces to the resonant scattering of photons, moving in the electromagnetic field of the signal, to the Rydberg complexes populated in a two-temperature non-equilibrium plasma. The processes of creation of additional photons because of stimulated emission and resonance scattering of photons are considered. In the present work, the quantum theory of the propagation of a satellite signal in the Earth’s upper atmosphere, firstly earlier proposed by the same authors, is described in detail. The general problems of the theory and possible theoretical and applied consequences are discussed. It is explained that two main processes occurring here, are directly related to the resonant quantum properties of the propagation medium. The first process leads to a direct increase in the power of the received signal, and second—to a shift in the signal carrier frequency?\"\"and the time delay?\"\"of its propagation. The main reasons of the processes are scattering of the Rydberg electron by the ion core and presence of the neutral medium molecule in the intermediate autoionization states of the composite system populated by the strong non-adiabatic coupling of electron and nuclear motions. The main purposes of our investigation are the physical justification of the formation of parameters \"\"and?
On filtering over ?to-Volterra observations
Michael V. Basin
International Journal of Stochastic Analysis , 2000, DOI: 10.1155/s1048953300000319
Abstract: In this paper, the Kalman-Bucy filter is designed for an Îto-Volterra process over Ito-Volterra observations that cannot be reduced to the case of a differential observation equation. The Kalman-Bucy filter is then designed for an Ito-Volterra process over discontinuous Ito-Volterra observations. Based on the obtained results, the filtering problem over discrete observations with delays is solved. Proofs of the theorems substantiating the filtering algorithms are given.
The trematodes and cestodes of Sorex araneus L. in Valaam Island (Ladoga Lake, USSR). 1
Novikov, Michael V.;
Memórias do Instituto Oswaldo Cruz , 1992, DOI: 10.1590/S0074-02761992000500031
Abstract: the trematode and the cestode fauna was examined in 50 specimens of common shrews sorex araneus l. (insectivora: soricidae) cillected in valaam island, urss during 1988 and 1989. two species of trematoda and seven species of cestoda were identified; prevalence of infection was as follows: brachulaemus fulvus (86% ), rubenstrema exasperatum (4% ), hymenolepis scutigera (54% ), neoskrjabinolepis schaldybini (26% ), vigisolepis spinulosa (4% ), choanotaenia crassiscolex (86% ), choanotaenia hepatica (6% ), dilepis undula (2% ) and polycercus sp. (2% ).
Nest emergence of smooth softshell turtle (Apalone mutica) hatchlings
Michael V. Plummer
Herpetological Conservation and Biology , 2007,
Abstract: I collected eggs from natural nests of Apalone mutica and reburied them in artificial nests constructed in a largeoutdoor enclosure. Toward the end of a known incubation period, nests were videotaped continuously until hatchlingsemerged. Most hatchlings emerged within a short period during a single day. Individuals emerged quickly and singly andmaintained brisk movement on the surface after emergence. Emergence times were normally distributed around a mediantime that corresponded with local sunset. Turtles emerged on sunny days when both nest and surface temperatures werebelow 36°C and on overcast days when nest and surface temperatures were relatively low and invariable. Timing of nestemergence has fitness consequences for hatchling freshwater turtles.
On a unique solution of a differential equation in vector distribution
Michael V. Basin
International Journal of Stochastic Analysis , 1994, DOI: 10.1155/s1048953394000468
On an infinite-dimensional differential equation in vector distribution with discontinuous regular functions in a right hand side
Michael V. Basin
International Journal of Stochastic Analysis , 1996, DOI: 10.1155/s1048953396000019
Abstract: An infinite-dimensional differential equation in vector distribution in a Hilbert space is studied in case of an unbounded operator and discontinuous regular functions in a right-hand side. A unique solution (vibrosolution) is defined for such an equation, and the necessary and sufficient existence conditions for a vibrosolution are proved. An equivalent equation with a measure, which enables us to directly compute jumps of a vibrosolution at discontinuity points of a distribution function, is also obtained. The application of the obtained results to control theory is discussed in the conclusion.
Pro- and Anti-Inflammatory Cytokine Networks in Atherosclerosis
Michael V. Autieri
ISRN Vascular Medicine , 2012, DOI: 10.5402/2012/987629
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