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Search Results: 1 - 10 of 200635 matches for " Michael H. Joseph "
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Evaluation of 2,4-D-Choline Based Herbicide Systems in 2,4-D Tolerant Soybean (Glycine max L.)  [PDF]
Dwayne D. Joseph, Colton H. Sanders, Michael W. Marshall
Agricultural Sciences (AS) , 2017, DOI: 10.4236/as.2017.85029
Abstract: Weeds are the most limiting factor in soybean production in South Carolina. With early emergence and rapid growth, weeds effectlively compete for water, nutrients, and light resources. The recent evolution of herbicide resistant weeds has made it increasingly difficult for growers to effectively control weeds in soybean. Glyphosate and ALS-resistant Palmer amaranth biotypes have spread rapidly throughout South Carolina, especially in areas where resistance management is lacking. Soybean varieties have been recently developed with tolerance to 2,4-D. Field experiments were conducted at the Clemson University Edisto Research and Education Center located near Blackville, SC in 2012 and 2013 to evaluate selected 2,4-D choline based herbicide programs for weed management in 2,4-D tolerant soybean. Overall, all herbicide treatments were effective in controlling weeds at the POST2 timing. Palmer amaranth control was excellent; however, pitted morningglory was the most difficult. The 2,4-D plus glyphosate pre-mixture provided excellent control for all three weed species with >95% control at POST2 timing. In these treatments, the rate of 2,4-D choline plus glyphosate (1.09 kg ae ha-1 or 1.64 kg ae ha-1) did not have a significant effect on weed control (P = 0.3772). There was a decrease in pitted morningglory control 3 WAP in 2012 vs 2013 in plots treated with S-metolachlor + fomesafen because of a lack of activating soil moisture in 2012. Results from this study showed that all treatments evaluated provided good to excellent control of all 3 weed species. Based on the herbicide programs evaluated in the study, herbicide resistant weeds, such as Palmer amaranth, can be effectively controlled when treated at the correct growth stage.
Efficacy of Selected Herbicide Programs in 2,4-D Tolerant Cotton (Gossypium hirsutum L.)  [PDF]
Colton H. Sanders, Dwayne D. Joseph, Michael W. Marshall
Agricultural Sciences (AS) , 2017, DOI: 10.4236/as.2017.810084
The use of transgenic crops has grown significantly over the past couple of decades. Many agronomic crops produced today are tolerant to glyphosate. Glyphosate-tolerant crops were commercially introduced in 1996, and, about nine years later, glyphosate-resistant Palmer amaranth was confirmed in Georgia. Glyphosate-resistant weeds arose from reliance on postemergence only glyphosate programs to control weeds in crops. New transgenic traits for glufosinate and 2,4-D choline have been developed, and evaluations of stacked traits and concurrent use of multiple herbicides have provided additional tools in the management of glyphosate-resistant weeds. Field experiments were conducted in 2012 and 2013 at the Edisto Research and Education Center near Blackville, SC, USA to determine the efficacy of 2,4-D-based herbicide programs in transgenic cotton tolerant to 2,4-D choline, glyphosate, and glufosinate. The treatments provided good to excellent Palmer amaranth and pitted morningglory control in 2012 and 2013. Seed cotton yields across treatments ranged from 0 to 2057 kg ha-1. This new trait technology package in cotton permits in-season postemergence use of 2,4-D choline, a herbicide mode of action not previously used postemergence in cotton, which can control resistant weeds, including Palmer amaranth if applied at the proper growth stage.
Palmer Amaranth (Amaranthus palmeri S. Wats.) and Pitted Morningglory (Ipomoea lacunosa L.) Control in Dicamba Tolerant Soybean (Glycine max L.)  [PDF]
Dwayne D. Joseph, Michael W. Marshall, Colton H. Sanders
American Journal of Plant Sciences (AJPS) , 2017, DOI: 10.4236/ajps.2017.813230
Abstract: Palmer amaranth and pitted morningglory are difficult to manage weeds present in South Carolina soybean production fields. Glyphosate and ALS-resistant Palmer amaranth biotypes have spread rapidly throughout South Carolina making the control of these weeds more difficult. Recently, soybean varieties with tolerance to dicamba have been introduced along with several new ultra-low volatility formulations of dicamba to help with the problem. Field experiments were conducted near Blackville, SC in 2012 and 2013 to evaluate dicamba herbicide programs for broadleaf weed management in dicamba tolerant soybean. At 2 weeks after POST1 (2 WAP1), Palmer amaranth control ranged from 93% to 100% across the PRE followed by POST treatments in 2012 and 2013. By 2 weeks after POST2 (2 WAP2), control was 95% or better. Treatments containing two or three herbicide applications (PRE, POST1 and POST2) offered good to excellent (92% - 100%) pitted morningglory control. No differences in weed control were observed among treatments with 3 application times compared to those applied twice. In general, all treatments with a PRE followed by at least one POST application provided good to excellent control of Palmer amaranth and pitted morningglory. Overall, a PRE (either dicamba or flumioxazin) followed by a dicamba or a non-dicamba containing POST treatment provided good to excellent control of Palmer amaranth and pitted morningglory when applied at the correct growth stage.
Efficacy of 2,4-D, Dicamba, Glufosinate and Glyphosate Combinations on Selected Broadleaf Weed Heights  [PDF]
Dwayne D. Joseph, Michael W. Marshall, Colton H. Sanders
American Journal of Plant Sciences (AJPS) , 2018, DOI: 10.4236/ajps.2018.96097
Abstract: Palmer amaranth, sicklepod and pitted morningglory are the three most common and troublesome weeds in soybean in South Carolina. They exhibit very aggressive growth capabilities and if left uncontrolled in fields will cause significant reductions in soybean yields. Dicamba and 2,4-D herbicides are currently having a resurgence in usage due to the recent commercialization of soybean trait technologies with tolerance to these herbicides. Dicamba and 2,4-D when tank mixed with glufosinate and glyphosate may offer additional weed control to resistant weeds through the process of herbicide synergism. Greenhouse experiments were conducted in 2013 at Edisto Research and Education Center near Blackville, SC to evaluate the efficacy of glyphosate, glufosinate, dicamba and 2,4-D treatments alone and in combination on Palmer amaranth, sicklepod, and pitted morningglory at selected heights. Results suggested that glufosinate alone provided the overall best control for all 3 weed species. Glyphosate alone provided the lowest control of all 3 species at all heights. Synergism or improved sicklepod control was observed when glufosinate was tank mixed with dicamba. However, as sicklepod increased in height, glufosinate + 2,4-D or dicamba combination offered the best control compared to glufosinate alone (90% versus 86% in 20 cm plants and 87% versus 85% in 30 cm plant). In the 5 cm Palmer amaranth, decreased control was observed when glyphosate or glufosinate was tank mixed with 2,4-D. These experiments showed that glufosinate alone and/or in combination with 2,4-D or dicamba was the overall best treatment on the three broadleaf weed species.
On the independence of Heegner points associated to distinct quadratic imaginary fields
Michael Rosen,Joseph H. Silverman
Mathematics , 2005,
Abstract: Let E/Q be an elliptic curve with a fixed modular parametrization F : X_0(N) --> E and let P_1,...,P_r be Heegner points on E attached to the rings of integers of distinct quadratic imaginary field k_1,...,k_r. We prove that if the odd parts of the class numbers of k_1,...,k_r are larger than a constant C=C(E,F) depending only on E and F, then the points P_1,...,P_r are independent in E/(torsion). We also discuss a possible application to the elliptic curve discrete logarithm problem.
Landen transforms as families of (commuting) rational self-maps of projective space
Michael Joyce,Shu Kawaguchi,Joseph H. Silverman
Mathematics , 2013,
Abstract: The classical (m,k)-Landen transform F_{m,k} is a self-map of the field of rational functions C(z) obtained by forming a weighted average of a rational function over twists by m'th roots of unity. Identifying the set of rational maps of degree d with an affine open subset of P^{2d+1}, we prove that F_{m,0} induces a dominant rational self-map R_{d,m,0} of P^{2d+1} of algebraic degree m, and for 0 < k < m, the transform F_{m,k} induces a dominant rational self-map R_{d,m,k} of algebraic degree m of a certain hyperplane in P^{2d+1}. We show in all cases that R_{d,m,k} extends nicely to a map of P^{2d+1} over Spec(Z), and that {R_{d,m,0} : m \ge 0} is a commuting family of maps.
On the Insignificant Cross-Sectional Risk-Return Relationship  [PDF]
Gerald H. L. Cheang, Joseph C. S. Kang, Michael Z. F. Li
Journal of Mathematical Finance (JMF) , 2012, DOI: 10.4236/jmf.2012.21004
Abstract: In their paper, “On the Cross-sectional Relation between Expected Returns and Betas”, Roll and Ross (1994) demonstrated that the expected returns and betas can have zero relationship even when the underlying market portfolio proxies are nearby the efficient frontier. In this note, we provide the mathematical details that lead to their conclusion and further show that their claim needs not hold for the entire set of MV portfolios.
“New-Look” Opioids: Biased Ligands  [PDF]
Joseph V. Pergolizzi, Michael H. Ossipov, Robert Taylor, Robert B. Raffa
Pharmacology & Pharmacy (PP) , 2018, DOI: 10.4236/pp.2018.97018
Abstract: Between the illicit use of opioids and attendant overdoses, and accidental overdoses with prescribed drugs, overuse of opioids has become a serious problem. At the same time, finding that fine balance between minimizing the risk of opioid misuse and abuse while at the same time providing access to treatment for patients who need pain control presents an ongoing challenge. Efforts to discover and develop better agents have led to what we term new-look opioids. We summarize here one such approach—known as biased ligands. By targeting a subset of GPCR signal transduction, this approach attempts to increase the separation between therapeutic and adverse effects.
Chylous ascites associated with chylothorax; a rare sequela of penetrating abdominal trauma: a case report
Joseph M Plummer, Michael E McFarlane, Arhcibald H McDonald
Journal of Medical Case Reports , 2007, DOI: 10.1186/1752-1947-1-149
Abstract: Although traumatic chylous ascites was first described in the 17th century by Morton [1] fewer than 100 cases have been reported in the world literature [2]. We recently managed a patient with chylous ascites resulting from penetrating trauma and who developed a right-sided chylous pleural effusion during the course of his treatment. This is the only case of combined chylous ascites and chylous pleural effusion resulting from penetrating trauma that we are aware of in the English medical literature. The management of this rare but potentially debilitating condition is discussed.A 19-year-old male was seen by the surgical team 14 hours after suffering a gunshot wound to the upper abdomen. On examination he was haemodynamically normal but he had a right pneumothorax for which a thoracostomy tube was inserted. His abdomen was distended with an entry gun-shot wound in the epigastrium four centimeters to the left of the midline and exit gun-shot wound posteriorly on the right at the level of the twelfth thoracic vertebra, eight centimeters from the midline. Neurological examination revealed lower limb paresis but there was no sensory deficit. Plain x-rays revealed full expansion of the lungs and a comminuted fracture to the lateral body of the T12 vertebra and the associated twelfth rib.He underwent mandatory exploratory laparotomy, which revealed 3.0 litres of blood, haemoperitoneum and a liver injury to segment four which was not actively bleeding. A small amount of clear fluid was noted to be accumulating in the retroperitoneum of the upper abdomen but its origin was unclear.His thoracostomy tube was removed and he was discharged five days after the laparotomy. The management plan for his vertebral fracture was non-operative with a brace and bed rest.The patient re-presented three weeks later with painless abdominal distension and shortness of breath. There was no history of vomiting or constipation. Examination of the abdomen revealed a non-tender distended abdomen w
Review of Salvage Therapy for Biochemically Recurrent Prostate Cancer: The Role of Imaging and Rationale for Systemic Salvage Targeted Anti-Prostate-Specific Membrane Antigen Radioimmunotherapy
Satyajit Kosuri,Naveed H. Akhtar,Michael Smith,Joseph R. Osborne,Scott T. Tagawa
Advances in Urology , 2012, DOI: 10.1155/2012/921674
Abstract: Despite local therapy with curative intent, approximately 30% of men suffer from biochemical relapse. Though some of these PSA relapses are not life threatening, many men eventually progress to metastatic disease and die of prostate cancer. Local therapy is an option for some men, but many have progression of disease following local salvage attempts. One significant issue in this setting is the lack of reliable imaging biomarkers to guide the use of local salvage therapy, as the likely reason for a low cure rate is the presence of undetected micrometastatic disease outside of the prostate/prostate bed. Androgen deprivation therapy is a cornerstone of therapy in the salvage setting. While subsets may benefit in terms of delay in time to metastatic disease and/or death, research is ongoing to improve salvage systemic therapy. Prostate-specific membrane antigen (PSMA) is highly overexpressed by the majority of prostate cancers. While initial methods of exploiting PSMA’s high and selective expression were suboptimal, additional work in both imaging and therapeutics is progressing. Salvage therapy and imaging modalities in this setting are briefly reviewed, and the rationale for PSMA-based systemic salvage radioimmunotherapy is described. 1. Prostate-Specific Antigen and Biochemical Relapse Clinically localized prostate cancer (PC) may have a variable, often protracted course from first diagnosis to metastasis [1, 2]. Despite recent controversies, prostate-specific antigen (PSA) has not only revolutionized diagnosis but is also used to monitor disease recurrence after primary treatment options such as radical prostatectomy (RP) or local definitive radiotherapy (RT). An important aspect of monitoring is the concept of biochemical recurrence (BCR) which can be defined within the framework of PSA. A primary definition had proven elusive as there are considerable differences between the primary therapies in regards to their PSA kinetics [3]. Following prostatectomy, absolute PSA values of 0.2–0.4?ng/mL are commonly used to define BCR, with a PSA of 0.4?ng/mL followed by another increase suggested for inclusion in clinical trials for men with BCR following RP [4, 5]. In the post-RT setting, an increase of 2?ng/mL from the patients’ post-RT nadir is used as the marker for recurrent/persistent disease (biochemical failure) [6]. In many parts of the world, the majority of men diagnosed with PC are usually well suited for local curative attempts with RP or RT. In this population it has been shown that BCR occurs in 12–42% [7] and 22–69% [8], respectively, overall
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