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Search Results: 1 - 10 of 8824 matches for " Miaofei Gu "
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Carboxylation of Aromatics by CO2 under “Si/Al Based Frustrated Lewis Pairs” Catalytic System  [PDF]
Miaofei Gu, Zhenmin Cheng
Journal of Materials Science and Chemical Engineering (MSCE) , 2015, DOI: 10.4236/msce.2015.31015
Abstract:

Carboxylation of aromatics by CO2 to generate corresponding carboxylic acids is recently providing a novel approach to utilize the green gas CO2, in which the activation of CO2 is the key procedure. Among the many catalytic systems employed in the carboxylation, the concept of “Frustrated Lewis Pairs” (FLPs) was scarcely mentioned, which perform excellently in activating small molecules like CO2. The FLPs are combinations of Lewis acids and Lewis bases which failed to form adducts due to their bulky steric congestion. In this paper, we first attempted various Si/Al Based FLPs to catalyze the carboxylation of aromatics through the activation of CO2, and a good yield of 62% - 97% was obtained. The reaction mechanism was proposed, involving the activation of CO2 mainly contributed by AlCl3 in cooperation with organosilane, forming an intermediate consisting of CO2, AlCl3, and R4Si, as well as the subsequent electrophilic attack to aromatics, thus to promote the carboxylation reaction.

Genetic Variants in Meiotic Program Initiation Pathway Genes Are Associated with Spermatogenic Impairment in a Han Chinese Population
Chuncheng Lu, Miaofei Xu, Ying Wang, Yufeng Qin, Guizhen Du, Wei Wu, Xiumei Han, Chao Ji, Yanli Yang, Aihua Gu, Yankai Xia, Ling Song, Shoulin Wang, Xinru Wang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0053443
Abstract: Background The meiotic program initiation pathway genes (CYP26B1, NANOS1 and STRA8) have been proposed to play key roles in spermatogenesis. Objective To elucidate the exact role of the genetic variants of the meiosis initiation genes in spermatogenesis, we genotyped the potential functional genetic variants of CYP26B1, NANOS1 and STRA8 genes, and evaluated their effects on spermatogenesis in our study population. Design, Setting, and Participants In this study, all subjects were volunteers from the affiliated hospitals of Nanjing Medical University between March 2004 and July 2009 (NJMU Infertile Study). Total 719 idiopathic infertile cases were recruited and divided into three groups according to WHO semen parameters: 201 azoospermia patients (no sperm in the ejaculate even after centrifugation), 155 oligozoospermia patients (sperm counts <20×106/ml) and 363 infertility/normozoospermia subjects (sperm counts >20×106/ml). The control group consisted of 383 subjects with normal semen parameters, all of which had fathered at least one child without assisted reproductive technologies. Measurements Eight single nucleotide polymorphisms (SNPs) in CYP26B1, NANOS1 and STRA8 genes were determined by TaqMan allelic discrimination assay in 719 idiopathic infertile men and 383 healthy controls. Results and Limitations The genetic variant rs10269148 of STRA8 gene showed higher risk of spermatogenic impairment in the groups of abnormospermia (including azoospermia subgroup and oligozoospermia subgroup) and azoospermia than the controls with odds ratios and 95% confidence intervals of 2.52 (1.29–4.94) and 2.92 (1.41–6.06), respectively (P = 0.006, 0.002 respective). Notably, larger sample size studies and in vivo or in vitro functional studies are needed to substantiate the biological roles of these variants. Conclusions Our results provided epidemiological evidence supporting the involvement of genetic polymorphisms of the meiotic program initiation genes in modifying the risk of azoospermia and oligozoospermia in a Han-Chinese population.
A Factorial Validation of Knowledge-Sharing Motivation Construct  [PDF]
Qinxuan Gu, Yingting Gu
Journal of Service Science and Management (JSSM) , 2011, DOI: 10.4236/jssm.2011.41009
Abstract: While there is increasingly strategic importance in knowledge, it is facing new challenges to manage knowledge effectively. The paper studies the motivational construct model for knowledge sharing from the perspective of content theories and social motivation theories. The data collected by using the questionnaire survey from a variety of industries was analyzed on the basis of interviews and pretest. The results of exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) showed the motivational construct model for knowledge sharing was comprised of existence motivation, relatedness motivation, growth motivation and norm motivation. The results extended the perspectives for knowledge sharing motivation and provided theoretical evidences for facilitating knowledge sharing behavior.
Construction and Characterization of Gal-Chitosan Graft Methoxy Poly(Ethylene Glycol)(Gal-CS-mPEG) Nanoparticles as Efficient Gene Carrier Construction and Characterization of Gal-Chitosan Graft Methoxy Poly(Ethylene Glycol)(Gal-CS-mPEG) Nanoparticles as Efficient Gene Carrier
JIN Jiting,FU Wandong,LIAO Miaofei,HAN Baoqin,CHANG Jing,YANG Yan
- , 2017,
Abstract: In the present study, galactosylated chitosan(Gal-CS) was conjugated with methoxy poly(ethylene glycol)(m PEG) as a hydrophilic group. The structure of Gal-CS-m PEG polymer was characterized and the nanoparticles(NPs) were prepared using ironic gelation method. The study was designed to investigate the characteristics and functions of Gal-CS-m PEG NPs. The morphology of Gal-CS-m PEG NPs was observed by SEM and it was a compact and spherical shape. The size of the NPs was approximately 200 nm in diameter under the ideal process parameters. The interaction between Gal-CS-m PEG NPs and p DNA, and the protection of p DNA against DNase I and serum degradation by Gal-CS-m PEG NPs were evaluated. Agarose gel electrophoresis results showed that Gal-CS-m PEG NPs had strong interaction with p DNA at the weight ratio of 12:1, 4:1 and 2:1 and could protect p DNA from DNase I and serum degradation. Gal-CS-m PEG NPs exhibited high loading efficiency and sustainable in vitro release. The blood compatibility studies demonstrated that Gal-CS-m PEG NPs had superior compatibility with erythrocytes in terms of aggregation degree and hemolysis level. Gal-CS-m PEG NPs showed no cytotoxicity on L929 cells, which is a normal mouse connective tissue fibroblast, but showed inhibitory effects on the proliferation of Bel-7402 cells, which is a liver cancer cell line. In conclusion, Gal-CS-m PEG NP is a bio-safe and efficient gene carrier with potential application in gene delivery
Multi-objective Optimization of Multi-Agent Elevator Group Control System Based on Real-time Particle Swarm Optimization Algorithm  [PDF]
Yanwu Gu
Engineering (ENG) , 2012, DOI: 10.4236/eng.2012.47048
Abstract: In order to get a globally optimized solution for the Elevator Group Control System (EGCS) scheduling problem, an algorithm with an overall optimization function is needed. In this study, Real-time Particle Swarm Optimization (RPSO) is proposed to find an optimal solution to the EGCS scheduling problem. Different traffic patterns and controller mechanisms for EGCS are analyzed. This study focuses on up-peak traffic because of its critical importance to modern office buildings. Simulation results show that EGCS based on Multi-Agent Systems (MAS) using RPSO gives good results for up-peak EGCS scheduling problem. Besides, the elevator real-time scheduling and reallocation functions are realized based on RPSO in case new information is available or the elevator becomes busy because it is unavailable or full. This study contributes a new scheduling algorithm for EGCS, and expands the application of PSO.
Research on the Cultivation of “Managerial” Accounting Talents’ IT Quality  [PDF]
Lingyan Gu
Open Journal of Accounting (OJAcct) , 2012, DOI: 10.4236/ojacct.2012.11002
Abstract: The rapid development of information technology puts forward higher request on the accounting personnel’s IT quality. This paper begins with the analysis about the information technologies which impact on accounting personnel in order to discuss what IT quality should be possessed by accounting personnel. Then according to the target of “managerial” accounting talents cultivation mode, it proposes several suggestions for the university about how to cultivate the “managerial” accounting talents’ IT quality.
The Allocation of Family Guanxi-Oriented Control Rights
—Evidence from Family Listed Companies of Zhejiang China
 [PDF]

Lingyan Gu
American Journal of Industrial and Business Management (AJIBM) , 2014, DOI: 10.4236/ajibm.2014.42016
Abstract:

Different from the market-oriented control mechanism in British and American, the guanxi-oriented control mechanism is a significant feature in Chinese family business. This paper proposes the concept of family guanxi-oriented control rights allocation for the first time. Based on the analysis about the influencing factors of the family guanxi-oriented control rights allocation, we use the sample companies coming from Zhejiang province of China to do further discussion. We find that 1) the actual controllers of Zhejiang family listed companies mainly have blood relationship; 2) parts of companies allocate the control rights between the family members who have more than three kinds of guanxi; 3) the controlling families prefer to control the board of the listed companies; 4) the intergenerational succession of control rights in Zhejiang family listed companies has been highlighted.

The Theoretical Analysis of the Allocation of Family Control Rights Based on Guanxi in China  [PDF]
Lingyan Gu
Open Journal of Business and Management (OJBM) , 2014, DOI: 10.4236/ojbm.2014.24037
Abstract: With the development of the family businesses, family members are coming from diversified source. Under this circumstance, guanxi and potential conflicts between family members are becoming complicated. The allocation of control rights among the family members plays an important role. This paper proposes the allocation concept of the family guanxi-oriented control rights for the first time. On the basis of the review of classical theories about the control rights allocation, it builds a theoretical analysis framework of family control rights allocation embedding guanxi.
Distorted Factor Markets, Government Intervention, and Excess Capital Accumulation: The Case of China  [PDF]
Tao Gu
Theoretical Economics Letters (TEL) , 2014, DOI: 10.4236/tel.2014.49102
Abstract: This paper develops a simple growth model that embeds distorted factor markets and government intervention that achieves high economic growth, low consumption, and high investment simultaneously. All of these phenomena are consistent with Chinese macroeconomic data since the 1990s, implying the inefficiency of economic growth.
Automated Scanning Electron Microscope Based Mineral Liberation Analysis An Introduction to JKMRC/FEI Mineral Liberation Analyser  [PDF]
Ying Gu
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2003, DOI: 10.4236/jmmce.2003.21003
Abstract: This paper presents the methods and techniques used in the recently developed JKMRC/FEI Mineral Liberation Analyser (MLA). The MLA system consists of a specially developed software package and a standard modern SEM fitted with an energy dispersive spectrum (EDS) analyser. The on-line program of the MLA software package controls the SEM, captures sample images, performs necessary image analysis and acquires EDS x-ray spectra unattended. Typically, 40 to 100 images (containing 4000 to 10,000 particles) are acquired for each sample block and a dozen blocks (of 30 mm in diameter) are measured overnight. The MLA off-line processing program transforms raw particle image with x-ray data into particle mineral maps and calculates bulk and liberation data from particle mineral maps.
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