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Search Results: 1 - 10 of 23526 matches for " Mi Hwi Kim "
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Polyphenol-Rich Fraction of Brown Alga Ecklonia cava Collected from Gijang, Korea, Reduces Obesity and Glucose Levels in High-Fat Diet-Induced Obese Mice
Eun Young Park,Eung Hwi Kim,Mi Hwi Kim,Young Wan Seo,Jung Im Lee,Hee Sook Jun
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/418912
Abstract: Ecklonia cava (E. cava) is a brown alga that has beneficial effects in models of type 1 and type 2 diabetes. However, the effects of E. cava extracts on diet-induced obesity and type 2 diabetes have not been specifically examined. We investigated the effects of E. cava on body weight, fat content, and hyperglycemia in high-fat diet- (HFD) induced obese mice and sought the mechanisms involved. C57BL/6 male mice were fed a HFD (60% fat) diet or normal chow. After 3 weeks, the HFD diet group was given extracts (200 mg/kg) of E. cava harvested from Jeju (CA) or Gijang (G-CA), Korea or PBS by oral intubation for 8 weeks. Body weights were measured weekly. Blood glucose and glucose tolerance were measured at 7 weeks, and fat pad content and mRNA expression of adipogenic genes and inflammatory cytokines were measured after 8 weeks of treatment. G-CA was effective in reducing body weight gain, body fat, and hyperglycemia and improving glucose tolerance as compared with PBS-HFD mice. The mRNA expression of adipogenic genes was increased, and mRNA expression of inflammatory cytokines and macrophage marker gene was decreased in G-CA-treated obese mice. We suggest that G-CA reduces obesity and glucose levels by anti-inflammatory actions and improvement of lipid metabolism.
Biodegradable stent  [PDF]
Doo Yeon Kwon, Jae Il Kim, Da Yeon Kim, Hwi Ju Kang, Bong Lee, Kang Woo Lee, Moon Suk Kim
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.54028
Abstract: The bare metal stent (BMS) used in the blood vessel caused the restenosis after the operation due to formation and proliferation of neointimal. Recently, as a method to overcome the problems of BMS, drug eluting stent (DES) is developed and being applied to human body which has drug reducing restenosis applied on the metal surface. DES has the advantage of greatly reducing the restenosis after the operation; however, metal stent remains in the body after the drug is released causing issues such as late thrombosis and restenosis so that currently the attention is increasing for biodegradable materials that reduce restenosis and thrombosis by degrading as a certain amount of time passes after the drug is released by the stent material. In this review, the study trend of biodegradable stent will be explained.
Latency Prolongation of P300 Event Related Potentials in Patients with and Without Asymptomatic Cerebral Infarction
Kim Kah Hwi,Chin Kah Chuan
Journal of Medical Sciences , 2005,
Abstract: In this study, we evaluate the changes on the Events-Related Potentials (ERPs) of P300 in patients with asymptomatic cerebral infarction which was detected by Magnetic Resonance Imaging (MRI). We examined 37 patients who visited University Hospital with complaint of headache or dizziness which had no episodes of stroke nor any neurological defect including obvious dementia between March 1988 to March 2000. MRI were performed and we found 23 cases of patients showed multiplelacunar infarction and 14 patients (8 male and 6 female) (with average age of 70) showed marked leuko-araiosis or periventricular high intensity with or without lacunar infarction in T2-weight image. We compared these two group with 13 healthy age-match (7 male and 6 female with average age of 68) as control group. ERPs was recorded with a band-pass filter of 0.01-120 c s-1. ERPs were derived from the Fz, Cz and Pz referenced to linked earlobe electrode and mini-mental test were performed in all subject. P300 ERPs were recorded by standard oddball paradigm with the subject seated in a reclined easy chair. In auditory paradigms, during the subject`s eyes were closed, 2,000 Hz tone were used as target and 1,000 Hz tone as none target through headphone. The target tone were presented in a random sequence at the rate of 20%. Then the subjects were instruct to count the number of target tone. Statistical analysis was performed using one factor ANOVA to determine inter-group differences. P300 latency in patients MRI showed multiple lacunar infarction (378.8 33.6 ms) and in patients MRI showed marked leuko-araiosis infarction (388.3 3.6 ms), were significantly prolonged as compare to normal healthy person (338.6 13.5 ms). However, the amplitude of P300 was remain unchanged. The scores obtained from Mini Mental State Test (MMST) were showed no significantly different between the normal elderly and patient with multiple lacunar infarction and in leuko-araiosis infarction patients Comparison the latency and amplitude of N100, P200 and N200 were also no significantly differences. The present finding, we found the P300 latency was significantly prolong in multiple lacunar infarction patients and in leuko-araiosis infarction patients. But there were no significant changes in the amplitude of P300. Thus, we can concluded that cognitive function was impaired with asymptomatic cerebral infarction.
Alternanthera sessilis Red Ethyl Acetate Fraction Exhibits Antidiabetic Potential on Obese Type 2 Diabetic Rats
Kok Keong Tan,Kah Hwi Kim
Evidence-Based Complementary and Alternative Medicine , 2013, DOI: 10.1155/2013/845172
Temporal Variations on Soil Salinity and Cation Displacement at Saemangeum and Yeongsangang Reclaimed Tidal Lands  [PDF]
Sanghun Lee, Hui-Su Bae, Hong-Kyu Kim, Tae-Hwan Noh, Geon-Hwi Lee
Journal of Agricultural Chemistry and Environment (JACEN) , 2014, DOI: 10.4236/jacen.2014.34014
Abstract: Soil salinity at reclaimed tidal land in Korea is highly variable and depending on soil characteristics and weather conditions. The objective of this study was to evaluate the temporal changes on soil salinity and the relationships between soil salinity and salinity parameters in reclaimed tidal lands. Soil samples were periodically collected at 0 - 20 cm (surface) and 20 - 40 cm (subsurface) layer at Saemangeum (sandy loam) and Yeongsangang (silty loam) reclaimed tidal land. Electrical conductivity (EC) had a wide range from 0.0 to 34.3 dS·m-1 during the experimental period. The average soil EC was 6.4 and 3.4 dS·m-1 at Saemangeum and Yeongsangang reclaimed tidal land, respectively. Soluble sodium concentration had great variations and it was the most important single factor for temporal variations of soil EC regardless of soil textural properties. Calcium concentration was negatively correlated with soil EC and soluble sodium. Soil exchangeable sodium percentage (ESP) was estimated as a function of soil sodium adsorption ratio (SAR) and a linear regression model (ESP = 6.075 (SAR) + 0.677 for Saemangeum and ESP = 3.925 (SAR) + 0.421 for Yeongsangang reclaimed tidal soil) was suggested for predicting soil ESP from soil SAR. The characteristics of reclaimed tidal lands had different shares of saline and sodic properties during the experimental period. Saemangeum reclaimed tidal soil was highly characterized by sodium, but the effect of sodium on Yeongsangang soil was less pronounced. Our results indicate that persistent monitoring and modeling on soil salinity at reclaimed tidal soil is fundamental and the results can provide some useful information for deciding management plans for diverse utilization or to reduce salt damage for stable crop production at reclaimed tidal land.
Reduction of Oxidative Stress Attenuates Lipoapoptosis Exacerbated by Hypoxia in Human Hepatocytes
Sang Youn Hwang,Su Jong Yu,Jeong-Hoon Lee,Hwi Young Kim,Yoon Jun Kim
International Journal of Molecular Sciences , 2015, DOI: 10.3390/ijms16023323
Abstract: Chronic intermittent hypoxia, a characteristic of obstructive sleep apnea (OSA), is associated with the progression of simple hepatic steatosis to necroinflammatory hepatitis. We determined whether inhibition of a hypoxia-induced signaling pathway could attenuate hypoxia-exacerbated lipoapoptosis in human hepatocytes. The human hepatocellular carcinoma cell line (HepG2) was used in this study. Palmitic acid (PA)-treated groups were used for two environmental conditions: Hypoxia (1% O 2) and normoxia (20% O 2). Following the treatment, the cell viability was determined by the 3,4-(5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt (MTS) assay, and the mechanism of lipoapoptosis was evaluated by Western blotting. Hypoxia exacerbated the suppression of hepatocyte growth induced by palmitic acid via activation of mitochondrial apoptotic pathways as a result of endoplasmic reticulum (ER) and oxidative stresses. Ammonium pyrrolidine dithiocarbamate, a scavenger of reactive oxygen species, attenuated the hypoxia-exacerbated lipoapoptosis in hepatocytes, whereas glycerol, which reduces ER stress, did not. This may have been because inhibition of oxidative stress decreases the expression of pro-apoptotic proteins, such as caspase 9 and cytochrome c. These results suggested that modulation of apoptotic signaling pathways activated by oxidative stress can aid in identifying novel therapeutic strategies for the treatment of nonalcoholic steatohepatitis (NASH) with OSA. Further in vivo studies are necessary to understand the pathophysiologic mechanism of NASH with OSA and to prove the therapeutic effect of the modulation of the signaling pathways.
Fast Neutron Detector for Fusion Reactor KSTAR Using Stilbene Scintillator
Seung Kyu Lee,Byoung-Hwi Kang,Gi-Dong Kim,Yong-Kyun Kim
Physics , 2011, DOI: 10.1088/1748-0221/7/06/C06013
Abstract: Various neutron diagnostic tools are used in fusion reactors to evaluate different aspects of plasma performance, such as fusion power, power density, ion temperature, fast ion energy, and their spatial distributions. The stilbene scintillator has been proposed for use as a neutron diagnostic system to measure the characteristics of neutrons from the Korea Superconducting Tokamak Advanced Research (KSTAR) fusion reactor. Specially designed electronics are necessary to measure fast neutron spectra with high radiation from a gamma-ray background. The signals from neutrons and gamma-rays are discriminated by the digital charge pulse shape discrimination (PSD) method, which uses total to partial charge ratio analysis. The signals are digitized by a flash analog-to-digital convertor (FADC). To evaluate the performance of the fabricated stilbene neutron diagnostic system, the efficiency of 10 mm soft-iron magnetic shielding and the detection efficiency of fast neutrons were tested experimentally using a 252Cf neutron source. In the results, the designed and fabricated stilbene neutron diagnostic system performed well in discriminating neutrons from gamma-rays under the high magnetic field conditions during KSTAR operation. Fast neutrons of 2.45 MeV were effectively measured and evaluated during the 2011 KSTAR campaign.
The Reducibility of a Special Binary Pentanomial
Ryul Kim,Yun Mi Kim
Algebra , 2014, DOI: 10.1155/2014/482837
Abstract: Swan’s theorem determines the parity of the number of irreducible factors of a binary trinomial. In this work, we study the parity of the number of irreducible factors for a special binary pentanomial with even degree , where , and exactly one of?? ,??and?? is odd. This kind of irreducible pentanomials can be used for a fast implementation of trace and square root computations in finite fields of characteristic 2. 1. Introduction Irreducible polynomials of low weight over a finite field are frequently used in many applications such as coding theory and cryptography due to efficient arithmetic implementation in an extension field and, thus, it is important to determine the irreducibility of such polynomials. The weight of a polynomial means the number of its nonzero coefficients. Characterization of the parity of the number of irreducible factors of a given polynomial is of significance in this context. If a polynomial has an even number of irreducible factors, then it is reducible and, thus, the study on the parity of this number can give a necessary condition for irreducibility. Swan [1] gives the first result determining the parity of the number of irreducible factors of trinomials over . Vishne [2] extends Swan’s theorem to trinomials over an even-dimensional extension of . Many Swan-like results focus on determining the reducibility of higher weight polynomials over ; see for example [3, 4]. Some researchers obtain the results on the reducibility of polynomials over a finite field of odd characteristic. We refer to [5, 6]. On the other hand, Ahmadi and Menezes [7] estimate the number of trace-one elements on the trinomial and pentanomial bases for a fast and low-cost implementation of trace computation. They also present a table of irreducible pentanomials whose corresponding polynomial bases have exactly one trace-one element. Each pentanomial of even degree in this table is of the form , where , and exactly one of ,??and?? is odd. In this work, we characterize the parity of the number of irreducible factors of this pentanomial. We describe some preliminary results related to Swan-like results in Section 2 and determine the reducibility of the pentanomial mentioned above in Section 3. 2. Preliminaries In this section, we recall Swan’s theorem determining the parity of the number of irreducible factors of a polynomial over and some results about the discriminant and the resultant of polynomials. Let be a field and let , where are the roots of in an extension of . The discriminant of is defined by From the definition, it is clear that has a repeated
The 'Instrumental' Reality of Phlogiston
Mi Gyung Kim
Hyle : International Journal for Philosophy of Chemistry , 2008,
Abstract: The stability of phlogiston in eighteenth-century French chemistry depended not on its role as a comprehensive theory, but on its operational (instrumental), theoretical, and philosophical (speculative) identities that were forged in different contexts, yet were interwoven to designate a single substance. It was as 'real' as any other chemical substance to the degree that it was obtained through material operations, occupied a place in the theoretical edifice of the affinity table, and was endowed with a corpuscular ontology. Lavoisier labeled it as an 'imaginary' substance because it offered a unique resistance to his vision of the new chemistry based on 'metric' measurements and algebraic representations.
Wilhelm Ostwald (1853-1932) (biography)
Mi Gyung Kim
Hyle : International Journal for Philosophy of Chemistry , 2006,
Abstract: biography of Wilhelm Ostwald (1853-1932)
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