oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 10 of 2998 matches for " Mery Guerrero "
All listed articles are free for downloading (OA Articles)
Page 1 /2998
Display every page Item
estatinas afectan la viabilidad de líneas celulares de leucemia y linfoma humanas in vitro
Guerrero,Mery; Di Giulio,Camilo; De Sanctis,Juan Bautista;
Revista de la Facultad de Medicina , 2010,
Abstract: statins have been proposed to induce apoptosis of tumor cells. in order to test this hypothesis, the effect of atorvastatin, fluvastatin, lovastatin, mevastatin, pravastatin, simvastatin on cell viability was assessed by in vitro culture for 48 hr, at concentrations ranging from 1 pm to 100 μm on human cell lines jurkat e6.1, jurkat d1.1 (t cell lymphoma), daudi (b cell lymphoma), u937 (monocitic leukemia) and hl-60 (pro mielomonocitic leukemia) and analyzed the oxidation of (3-(4.5-dimethylthiazol-2-yl)-2.5- diphenyltetrazolium bromide (mtt). lovastatin and mevastatin are the most potent inductors of cell death independently of the cell type (ic 50 between 12 and 50 μm). differences in the ic50 are observed depending on the cell line: atorvastatina (38.1 and 48.6 μm jurkats, 55.3 μm daudi y 100 μm for the others lines), pravastatin (25 μm hl-60, 55.6 y 60.7 μm jurkats and ≥ 100 μm daudi and u937), simvastatin (25.1 μm jurkat d1.1, 50.2 μm jurkat e6.1, 45.2 μm daudi and 51,3 μm hl-60, and > 100 μm u937) and for fluvastatin > 100 μm in all cases. the decrease in cell viability is reverted completely when the cells were incubated with 10 μm mevalonate. it is concluded that lovastatin and mevastatin are the most potent inductors of cell death followed by atorvastatin, pravastatin and simvastatin whose effect depends upon the cell type and fluvastatin does not have any important effects on cell viability on the cell lines studied.
estatinas afectan la viabilidad de líneas celulares de leucemia y linfoma humanas in vitro
Mery Guerrero,Camilo Di Giulio,Juan Bautista De Sanctis
Revista de la Facultad de Medicina , 2010,
Abstract: Se ha propuesto que las estatinas inducen apoptosis sobre células tumorales. Para probar dicha hipótesis, se analizó el efecto de las estatinas atorvastatina, fluvastatina, lovastatina, mevastatina, pravastatina y simvastatina en el rango de concentraciones de 1 pM hasta 100 μM, sobre la viabilidad de las líneas celulares humanas Jurkat E6.1, Jurkat D1.1 (Linfoma T) , Daudi (Linfoma B), U937 (leucemia monocítica) y HL-60 (leucemia promielomonocítica) in vitro en cultivos de 48 horas, analizados por la técnica de hidrolización del compuesto bromuro de 3-(4,5-dimetiltiazol-2-il)-2,5-difenilltetrazolio (MTT). Lovastatina y mevastatina son los más potentes inductores de muerte celular independientemente del tipo celular (Ic 50 entre 12 y 50 μM). Para las otras estatinas se observan diferencias en el Ic50 según la línea celular atorvastatina (38,1 y 48,6 μM Jurkats, 55,3 μM Daudi y 100 μM para las otras líneas), pravastatina (25 μM HL-60, 55,6 y 60,7 μM Jurkats y ≥ 100 μM Daudi y U937), simvastatina (25,1 μM Jurkat D1.1, 50,2 μM Jurkat E6.1, 45,2 μM Daudi y 51,3 μM HL-60, y > 100 μM U937) y para fluvastatina en todos los casos > 100 μM. La disminución de la viabilidad celular se revierte completamente cuando las células son incubadas con 10 μM mevalonato. Se concluye que la lovastatina y mevastatina son las más potentes inductoras de muerte seguida por atorvastatina, pravastatina y simvastatina cuyo efecto depende del tipo de línea celular y la fluvastatina no tiene efectos importantes en la viabilidad de las líneas celulares estudiadas. Statins have been proposed to induce apoptosis of tumor cells. In order to test this hypothesis, the effect of atorvastatin, fluvastatin, lovastatin, mevastatin, pravastatin, simvastatin on cell viability was assessed by in vitro culture for 48 hr, at concentrations ranging from 1 pM to 100 μM on human cell lines Jurkat E6.1, Jurkat D1.1 (T cell lymphoma), Daudi (B cell lymphoma), U937 (monocitic leukemia) and HL-60 (pro mielomonocitic leukemia) and analyzed the oxidation of (3-(4.5-Dimethylthiazol-2-yl)-2.5- diphenyltetrazolium bromide (MTT). Lovastatin and mevastatin are the most potent inductors of cell death independently of the cell type (Ic 50 between 12 and 50 μM). Differences in the Ic50 are observed depending on the cell line: atorvastatina (38.1 and 48.6 μM Jurkats, 55.3 μM Daudi y 100 μM for the others lines), pravastatin (25 μM HL-60, 55.6 y 60.7 μM Jurkats and ≥ 100 μM Daudi and U937), simvastatin (25.1 μM Jurkat D1.1, 50.2 μM Jurkat E6.1, 45.2 μM Daudi and 51,3 μM HL-60, and > 100 μM U937) and for fluvastatin >
Tecnología y Neurocirugía Technology and Neurosurgery
Francisco Mery
Revista Chilena de Neuro-Psiquiatría , 2010,
Abstract:
Book Review - A Linguagem das Coisas
Mery Blanck
Revista de Administra??o Contemporanea , 2011,
Abstract:
Las aficiones musicales de los alumnos de las diplomaturas de magisterio
Israel, Mery
Revista de la Lista Electrónica Europea de Música en la Educación , 2003,
Abstract: Este artículo es parte de una investigación realizada a los alumnos de las Diplomaturas de Magisterio de la Comunidad Autónoma Andaluza, en la que se pretendía conocer entre otros aspectos sus aficiones musicales. En particular hemos intentado plasmar la importancia de fomentar las aficiones musicales por la repercusión que a nivel personal y como medio educativo de formación intelectual e instructivo tienen para quienes las practican, así como su repercusión sociocultural. Dando así mismo una visión de las aficiones musicales más destacadas entre los alumnos encuestados.
Importancia del diagnóstico confirmatorio en enfermedades exantemáticas de etiología viral en el estado Zulia, Venezuela: una revisión del problema
Valero,Nereida; Maldonado,Mery;
Investigación Clínica , 2006,
Abstract: a great variety of viruses which cause exanthema share other clinical manifestations, making etiologic identification relying exclusively on clinical examination a very difficult task. the most common agents include the measles virus, rubella, dengue, varicella, cytomegalovirus, epstein barr, enteroviruses, human parvovirus b19 and type 6 human herpes virus. the fact that most these diseases are self limited represents an important challenge to the development of clinical and epidemiological resources, identification of new infectious agents, monitor changes in their behavior, and to evaluate the impact of immunization on the modification of viral disease with cutaneous manifestations that are considered along whit classical exanthematic pathology, and specially the macullopapular type. in spite the fact that viral exanthematic diseases are common in zulia state, several difficulties are encountered in order to determine a precise etiologic diagnosis. even though some are fairly benign and self limited, some represent an important risk to certain age groups, gravid and immunocompromized patients, since they can progress to more serious processes. therefore it is of great importance to ascertain the etiological diagnosis that might be implicated with viral exanthematic diseases in order to guarantee an adequate treatment and to establish the required measures for disease control.
La gestación: proceso de preparación de la mujer para el nacimiento de su hijo(a)
HERNáNDEZ,LUZ MERY;
Avances en Enfermería , 2008,
Abstract: the objective of this research is to describe the meaning of self care of one self as well as of the unborn child based on values, beliefs and practices, for a group of gestating women from the district of engativá. this is a qualitative ethnographic study using the ethnonursing method developed by madeleine leininger. this research was carried out with the participation of 8 gestating women, aged between 18 and 30 years of age, with low risk gestation, who attended prenatal control at the upa la espa?ola from "localidad 10" in bogotá, during the period between january and august 2005, who shared on an everyday basis their knowledge and experiences in a natural and spontaneous way with the researcher, who, to achieve this, behaved as a apprentice. based on this dynamics, the transmission of cultural knowledge by the gestating women was encouraged, and the subject "gestation: process of preparation of women's cultural knowledge for her child's birth", from which two different cultural domains arise: readiness for their child's birth and appropriate feeding practices.
Estructura organizativa y trayectoria de un grupo de investigación científica de relaciones internacionales
Hamui Sutton, Mery;
Perfiles educativos , 2011,
Abstract: in this article, the author carries out a theoretical-empirical comparison about the way in which the organization structure and the logics of change are brought about in a succesful research team in social sciences (international relations) in the public sector by analyzing its career experience. the measurements of the organizational structures were: a) functional stabilization, which includes its composition, orientation, regulating action, differentiation and leaderschip; and b) emotional stabilization, which considers the status of membership. about this particular aspect the author shows how the member of the team uses to estimate the costs and benefits to be member of the group for the production of knowledge, to build up an ethos, roles, identities and power in the interaction logics. the author also compares the typical model of career of the research teams with this particular team in three specific moments: forming, transition to consolidation and consolidation.
Ethos en la trayectoria de dos grupos de investigación científica de ciencias básicas de la salud
Hamui Sutton, Mery;
Revista de la educación superior , 2010,
Abstract: from theoretical and empirical elements, the ethos is analyzed in the trajectory of two groups of the basic sciences of health, immunochemistry and immunology, to explain how they produce scientific knowledge. for the ethos, the identity and the relations between the type of knowledge and the own guidelines of interaction of discipline, training and the attitude of the members reflect the actions among others were analyzed. an explanation over the path followed in the conformation, transition and consolidation of the ethos of the studied groups its also presented.
Estructura de organización en la trayectoria de dos grupos de investigación científica de Ciencias Básicas de la Salud en la generación de conocimiento
Hamui Sutton, Mery;
Revista mexicana de investigación educativa , 2010,
Abstract: this article attempts to show how organizational structure operates as a source of emotional and functional stability for the production of scientific knowledge, as well as the logic of change, in successful scientific research groups in academia and the public sector. the paper presents the results of the organizational structure of two research groups-immunochemistry and immunology-in two dimensions: a) functional stabilization and relative permanence of a group, including composition, orientation, normative action, differentiation and leadership, and b) emotional stabilization, whose dimensions are belonging, in which the group member calculates the costs and benefits of being a member to attain ends, the construction of an ethos, roles, identities, and power in the logic of interaction. also shown is the process of conforming a new group in immunology during the consolidation of the trajectory of the immunochemistry group, as a process of reproduction of research groups in new lines of specialized knowledge.
Page 1 /2998
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.